This invention describes a class of compounds able to activate the human SIRT1 enzyme and regulate many metabolic functions. This invention consists of compounds that can be employed in medical applications, specifically for the treatment or prevention of cardiometabolic diseases, such as diabetes, and of cardiovascular disorders, such as coronaropathy, heart failure and atherosclerosis.
New activators of SIRT1 enzyme for the treatment of cardiovascular and cardiometabolic pathologies
CALDERONE Vincenzo;MINUTOLO Filippo;TUCCINARDI Tiziano;TESTAI Lara;GRANCHI Carlotta;MARTELLI Alma;CITI Valentina;
2019-01-01
Abstract
This invention describes a class of compounds able to activate the human SIRT1 enzyme and regulate many metabolic functions. This invention consists of compounds that can be employed in medical applications, specifically for the treatment or prevention of cardiometabolic diseases, such as diabetes, and of cardiovascular disorders, such as coronaropathy, heart failure and atherosclerosis.File in questo prodotto:
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Patent_SIRT_WO2019162911A1_Original_document_20200116145118.pdf
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21.U0053.12.WO.5@Pub_(WO2019-162911-A8)_risposta depositata.pdf
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