POLI, GIULIO
 Distribuzione geografica
Continente #
NA - Nord America 3.520
EU - Europa 1.830
AS - Asia 532
AF - Africa 44
SA - Sud America 11
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.940
Nazione #
US - Stati Uniti d'America 3.473
IT - Italia 997
SE - Svezia 315
CN - Cina 175
BG - Bulgaria 166
SG - Singapore 157
VN - Vietnam 100
AT - Austria 88
GB - Regno Unito 77
DE - Germania 61
FR - Francia 60
CA - Canada 47
HK - Hong Kong 38
CI - Costa d'Avorio 26
IN - India 25
KR - Corea 13
FI - Finlandia 12
CZ - Repubblica Ceca 11
BE - Belgio 9
CH - Svizzera 9
TR - Turchia 8
SN - Senegal 7
UA - Ucraina 7
JP - Giappone 6
NG - Nigeria 6
BR - Brasile 5
RU - Federazione Russa 5
CO - Colombia 4
DZ - Algeria 4
GR - Grecia 3
PL - Polonia 3
AU - Australia 2
IR - Iran 2
KW - Kuwait 2
NL - Olanda 2
AR - Argentina 1
BD - Bangladesh 1
CL - Cile 1
EG - Egitto 1
EU - Europa 1
HR - Croazia 1
HU - Ungheria 1
ID - Indonesia 1
IQ - Iraq 1
IS - Islanda 1
KZ - Kazakistan 1
LK - Sri Lanka 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
SY - Repubblica araba siriana 1
Totale 5.940
Città #
Fairfield 593
Woodbridge 347
Serra 323
Ashburn 277
Seattle 253
Houston 244
Chandler 213
Wilmington 201
Cambridge 177
Sofia 165
Milan 152
Ann Arbor 148
New York 108
Princeton 105
Boardman 103
Beijing 84
Vienna 74
Lawrence 63
Pisa 63
Medford 62
London 54
Singapore 51
Boulder 44
Dong Ket 44
Ottawa 40
Hong Kong 38
Des Moines 32
Marseille 32
Rome 31
Nanjing 28
Redwood City 27
Abidjan 26
Livorno 25
San Diego 24
Ogden 22
Florence 20
Dearborn 15
Hyderabad 15
Munich 14
Los Angeles 13
Pistoia 13
Brno 10
Guangzhou 10
San Francisco 10
Pessac 9
Seongbuk-gu 9
Dallas 8
Dakar 7
Frankfurt am Main 7
Hebei 7
Jacksonville 7
Nanchang 7
Norwalk 7
Bern 6
Brussels 6
Lagos 6
Tokyo 6
Genoa 5
Izmir 5
Massa Marittima 5
Pune 5
Toronto 5
Campiglia Marittima 4
Cascina 4
Fisciano 4
Fort Worth 4
Lucca 4
Montopoli in Val d'Arno 4
Palermo 4
Pescara 4
Rho 4
Shanghai 4
Shenyang 4
Siena 4
Talence 4
Zhengzhou 4
Bientina 3
Cesa 3
Detroit 3
Hangzhou 3
Indiana 3
Kunming 3
Massa 3
Massarosa 3
Pieve 3
Piombino 3
São Paulo 3
Treviso 3
Viareggio 3
Vicopisano 3
Warsaw 3
Washington 3
Zurich 3
Ürümqi 3
Auburn Hills 2
Calci 2
Camerino 2
Castelfidardo 2
Catania 2
Cecina 2
Totale 4.632
Nome #
Anticancer activity of euplotin C, isolated from the marine ciliate euplotes crassus, against human melanoma cells 192
Receptor-based virtual screening evaluation for the identification of estrogen receptor β ligands 183
Identification of Lactate Dehydrogenase 5 Inhibitors using Pharmacophore- Driven Consensus Docking 166
Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system 149
Synthesis and Biological Evaluation of New Glycoconjugated LDH Inhibitors as Anticancer Agents 144
Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor 140
Aldose reductase differential inhibitors in green tea 131
Identification of new FYN kinase inhibitors using a FLAP-based approach 126
A Virtual Screening Study for Lactate Dehydrogenase 5 Inhibitors by using a Pharmacophore-Based Approach 125
Reliability analysis and optimization of the consensus docking approach for the development of virtual screening studies 124
The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation 119
Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors 116
Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors 112
Identification of a new STAT3 dimerization inhibitor through a pharmacophore-based virtual screening approach 110
Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors 110
Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors 108
Extensive consensus docking evaluation for ligand pose prediction and virtual screening studies 105
Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system 103
Novel 8-substituted coumarins that selectively inhibit human carbonic anhydrase IX and XII 102
Development of a Fingerprint-Based Scoring Function for the Prediction of the Binding Mode of Carbonic Anhydrase II Inhibitors 100
Computational Approaches for the Identification and Optimization of Src Family Kinases Inhibitors. 95
Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment 95
Three-dimensional analysis of the interactions between hLDH5 and its inhibitors 93
First-of-its-kind STARD 3 Inhibitor: In Silico Identification and Biological Evaluation as Anticancer Agent 91
Targeting GLUT1 in acute myeloid leukemia to overcome cytarabine resistance 90
Drug Affinity Responsive Target Stability (DARTS) Identifies Laurifolioside as a New Clathrin Heavy Chain Modulator 89
New diterpenes from Salvia pseudorosmarinus and their activity as inhibitors of monoacylglycerol lipase (MAGL) 86
Synthesis and structure activity relationship investigation of triazolo[1,5-a]pyrimidines as CB2 cannabinoid receptor inverse agonists 86
Application of MM-PBSA methods in virtual screening 84
Extensive reliability evaluation of docking-based target-fishing strategies 81
The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel 81
New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents 80
Pyridazinone-substituted benzenesulfonamides display potent inhibition of membrane-bound human carbonic anhydrase IX and promising antiproliferative activity against cancer cell lines 79
Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles 78
An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present) 78
Discovery and development of novel salicylate synthase (MbtI) furanic inhibitors as antitubercular agents 78
3D Pharmacophore Modeling Techniques in Computer-Aided Molecular Design Using LigandScout 77
null 77
Application of a FLAP-Consensus Docking Mixed Strategy for the Identification of New FAAH Inhibitors 75
Virtual screening identifies a PIN1 inhibitor with possible antiovarian cancer effects 74
New Chromane-Based Derivatives as Inhibitors of Mycobacterium tuberculosis Salicylate Synthase (MbtI): Preliminary Biological Evaluation and Molecular Modeling Studies 72
Antibacterial and ATP Synthesis Modulating Compounds from Salvia tingitana 72
N-aryl-N’-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties 71
null 71
1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors 68
Conformational sampling of small molecules with iCon: Performance assessment in comparison with OMEGA 67
Rutin as promising drug for the treatment of Parkinson’s disease: an assessment of MAO-B inhibitory potential by docking, molecular dynamics and DFT studies 67
Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site-directed mutagenesis 66
The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis 66
Novel broad spectrum virucidal molecules against enveloped viruses 65
Nuovi inibitori reversibili della monoacilglicerolo lipasi (MAGL) quali potenziali agenti antitumorali, antiinfiammatori e neuroprotettivi. 64
Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides 63
Largazole Analogues as Histone Deacetylase Inhibitors and Anticancer Agents: An Overview of Structure–Activity Relationships 57
L-DOPA-quinone Mediated Recovery from GIRK Channel Firing Inhibition in Dopaminergic Neurons 57
New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2 54
null 51
Discovery of novel µ-opioid receptor inverse agonist from a combinatorial library of tetrapeptides through structure-based virtual screening 46
Consensus Docking in Drug Discovery 46
Three-dimensional interactions analysis of the anticancer target c-src kinase with its inhibitors 45
null 44
New Synthetic Analogues of Natural Polyphenols as Sirtuin 1-Activating Compounds 44
Monoacylglycerol lipase (MAGL) Inhibitors 42
Discovery of monoacylglycerol lipase (MAGL) inhibitors based on a pharmacophore-guided virtual screening study 41
Mealworm (Tenebrio molitor): Potential and challenges to promote circular economy 38
Carbonic Anhydrase Inhibitors: Identifying Therapeutic Cancer Agents Through Virtual Screening 38
Recent advances in in silico target fishing 34
Nuovi agenti antivirali a struttura N-idrossiindrol-carbossamidica 33
From Anti-infective Agents to Cancer Therapy: a Drug Repositioning Study Revealed a New Use for Nitrofuran Derivatives 33
Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors 32
Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design 31
Dissecting the Activity of Catechins as Incomplete Aldose Reductase Differential Inhibitors through Kinetic and Computational Approaches 30
Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives 30
null 30
Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives 28
New PIN1 inhibitors identified through a pharmacophore-driven, hierarchical consensus docking strategy 25
Virtual screening and crystallographic studies reveal an unexpected γ-lactone derivative active against MptpB as a potential antitubercular agent 25
Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study 23
Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1H)-One Scaffold 22
Predicting potentially pathogenic effects of hRPE65 missense mutations: a computational strategy based on molecular dynamics simulations 17
Antibacterial alkylguanidino ureas: Molecular simplification approach, searching for membrane-based MoA 17
Monoacylglycerol lipase (MAGL) inhibitors based on a diphenylsulfide-benzoylpiperidine scaffold 14
Resveratrol Analogues as Dual Inhibitors of Monoamine Oxidase B and Carbonic Anhydrase VII: A New Multi-Target Combination for Neurodegenerative Diseases? 14
Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin 13
Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors 13
VenomPred: A Machine Learning Based Platform for Molecular Toxicity Predictions 13
Sirtuin 1-activating derivatives belonging to the anilinopyridine class displaying in vivo cardioprotective activities 12
Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study 11
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety 11
Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors 10
An in silico toolbox for the prediction of the potential pathogenic effects of missense mutations in the dimeric region of hRPE65 9
Identification of New GSK3β Inhibitors through a Consensus Machine Learning-Based Virtual Screening 8
A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration 6
Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors 5
An update on antibacterial AlkylGuanidino Ureas: Design of new derivatives, synergism with colistin and data analysis of the whole library 4
miRNA-203b-3p Induces Acute and Chronic Pruritus through 5-HTR2B and TRPV4 4
MolBook UNIPI─Create, Manage, Analyze, and Share Your Chemical Data for Free 4
N-aryl-N′-ureido-O-sulfamates as potent and selective inhibitors of hCA VB over hCA VA: Deciphering the binding mode of new potential agents in mitochondrial dysfunctions 2
Totale 6.210
Categoria #
all - tutte 21.044
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.044


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.219 0 0 86 110 136 166 139 128 140 111 84 119
2020/2021839 87 64 43 39 41 85 23 59 140 76 50 132
2021/2022913 46 45 26 63 123 142 33 46 52 46 46 245
2022/20231.027 131 162 110 74 83 118 30 74 145 10 54 36
2023/2024939 70 92 93 56 137 139 82 26 14 27 73 130
2024/2025147 42 105 0 0 0 0 0 0 0 0 0 0
Totale 6.210