POLI, GIULIO
 Distribuzione geografica
Continente #
NA - Nord America 3.394
EU - Europa 1.802
AS - Asia 446
AF - Africa 44
SA - Sud America 11
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 5.700
Nazione #
US - Stati Uniti d'America 3.347
IT - Italia 976
SE - Svezia 315
CN - Cina 177
BG - Bulgaria 166
VN - Vietnam 100
AT - Austria 89
SG - Singapore 83
GB - Regno Unito 76
FR - Francia 67
DE - Germania 56
CA - Canada 47
HK - Hong Kong 42
CI - Costa d'Avorio 26
FI - Finlandia 12
KR - Corea 11
IN - India 10
BE - Belgio 9
CH - Svizzera 9
TR - Turchia 8
SN - Senegal 7
UA - Ucraina 7
JP - Giappone 6
NG - Nigeria 6
BR - Brasile 5
RU - Federazione Russa 5
CO - Colombia 4
DZ - Algeria 4
PL - Polonia 4
GR - Grecia 3
AU - Australia 2
IR - Iran 2
KW - Kuwait 2
NL - Olanda 2
AR - Argentina 1
BD - Bangladesh 1
CL - Cile 1
CZ - Repubblica Ceca 1
EG - Egitto 1
EU - Europa 1
HR - Croazia 1
HU - Ungheria 1
ID - Indonesia 1
IQ - Iraq 1
IS - Islanda 1
KZ - Kazakistan 1
LK - Sri Lanka 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 5.700
Città #
Fairfield 593
Woodbridge 347
Serra 323
Ashburn 277
Seattle 253
Houston 244
Chandler 213
Wilmington 201
Cambridge 177
Sofia 165
Milan 150
Ann Arbor 148
New York 110
Princeton 105
Beijing 85
Vienna 75
Lawrence 63
Medford 62
Pisa 55
London 53
Boulder 44
Dong Ket 44
Hong Kong 42
Ottawa 40
Marseille 33
Des Moines 32
Nanjing 28
Rome 28
Redwood City 27
Abidjan 26
San Diego 24
Livorno 22
Florence 16
Dearborn 15
Los Angeles 15
Pessac 13
Pistoia 13
Guangzhou 10
Pescara 10
San Francisco 10
Munich 8
Seongbuk-gu 8
Castel Focognano 7
Dakar 7
Frankfurt am Main 7
Hebei 7
Jacksonville 7
Nanchang 7
Norwalk 7
Bern 6
Brussels 6
Dallas 6
Lagos 6
Singapore 6
Talence 6
Tokyo 6
Izmir 5
Massa Marittima 5
Ogden 5
Pune 5
Toronto 5
Campiglia Marittima 4
Cascina 4
Fort Worth 4
Lucca 4
Montopoli in Val d'Arno 4
Rho 4
Shanghai 4
Shenyang 4
Siena 4
Warsaw 4
Washington 4
Zhengzhou 4
Bientina 3
Cesa 3
Detroit 3
Genoa 3
Hangzhou 3
Indiana 3
Kunming 3
Massa 3
Massarosa 3
Pieve 3
Piombino 3
São Paulo 3
Viareggio 3
Vicopisano 3
Zurich 3
Ürümqi 3
Auburn Hills 2
Calci 2
Camerino 2
Castelfidardo 2
Catania 2
Cecina 2
Chengdu 2
Chicago 2
Chiesina Uzzanese 2
Da Nang 2
Delhi 2
Totale 4.441
Nome #
Anticancer activity of euplotin C, isolated from the marine ciliate euplotes crassus, against human melanoma cells 190
Receptor-based virtual screening evaluation for the identification of estrogen receptor β ligands 181
Identification of Lactate Dehydrogenase 5 Inhibitors using Pharmacophore- Driven Consensus Docking 163
Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system 147
Synthesis and Biological Evaluation of New Glycoconjugated LDH Inhibitors as Anticancer Agents 141
Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor 137
Aldose reductase differential inhibitors in green tea 127
Identification of new FYN kinase inhibitors using a FLAP-based approach 124
A Virtual Screening Study for Lactate Dehydrogenase 5 Inhibitors by using a Pharmacophore-Based Approach 122
Reliability analysis and optimization of the consensus docking approach for the development of virtual screening studies 121
The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation 117
Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors 115
Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors 108
Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors 108
Identification of a new STAT3 dimerization inhibitor through a pharmacophore-based virtual screening approach 107
Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors 105
Extensive consensus docking evaluation for ligand pose prediction and virtual screening studies 104
Novel 8-substituted coumarins that selectively inhibit human carbonic anhydrase IX and XII 99
null 98
Development of a Fingerprint-Based Scoring Function for the Prediction of the Binding Mode of Carbonic Anhydrase II Inhibitors 97
Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment 93
Computational Approaches for the Identification and Optimization of Src Family Kinases Inhibitors. 92
Three-dimensional analysis of the interactions between hLDH5 and its inhibitors 91
First-of-its-kind STARD 3 Inhibitor: In Silico Identification and Biological Evaluation as Anticancer Agent 89
Targeting GLUT1 in acute myeloid leukemia to overcome cytarabine resistance 88
Synthesis and structure activity relationship investigation of triazolo[1,5-a]pyrimidines as CB2 cannabinoid receptor inverse agonists 85
New diterpenes from Salvia pseudorosmarinus and their activity as inhibitors of monoacylglycerol lipase (MAGL) 84
Drug Affinity Responsive Target Stability (DARTS) Identifies Laurifolioside as a New Clathrin Heavy Chain Modulator 83
Application of MM-PBSA methods in virtual screening 82
The acyl-glucuronide metabolite of ibuprofen has analgesic and anti-inflammatory effects via the TRPA1 channel 79
New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents 78
Extensive reliability evaluation of docking-based target-fishing strategies 78
Pyridazinone-substituted benzenesulfonamides display potent inhibition of membrane-bound human carbonic anhydrase IX and promising antiproliferative activity against cancer cell lines 77
null 77
Design, synthesis, docking studies and monoamine oxidase inhibition of a small library of 1-acetyl- and 1-thiocarbamoyl-3,5-diphenyl-4,5-dihydro-(1h)-pyrazoles 76
Discovery and development of novel salicylate synthase (MbtI) furanic inhibitors as antitubercular agents 76
3D Pharmacophore Modeling Techniques in Computer-Aided Molecular Design Using LigandScout 73
An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present) 73
Application of a FLAP-Consensus Docking Mixed Strategy for the Identification of New FAAH Inhibitors 72
Virtual screening identifies a PIN1 inhibitor with possible antiovarian cancer effects 72
null 71
New Chromane-Based Derivatives as Inhibitors of Mycobacterium tuberculosis Salicylate Synthase (MbtI): Preliminary Biological Evaluation and Molecular Modeling Studies 70
Antibacterial and ATP Synthesis Modulating Compounds from Salvia tingitana 70
N-aryl-N’-ureido-O-sulfamates: Potent and selective inhibitors of the human Carbonic Anhydrase VII isoform with neuropathic pain relieving properties 69
1,3-Dipolar Cycloaddition, HPLC Enantioseparation, and Docking Studies of Saccharin/Isoxazole and Saccharin/Isoxazoline Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors 66
Conformational sampling of small molecules with iCon: Performance assessment in comparison with OMEGA 65
Rutin as promising drug for the treatment of Parkinson’s disease: an assessment of MAO-B inhibitory potential by docking, molecular dynamics and DFT studies 65
Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site-directed mutagenesis 64
Novel broad spectrum virucidal molecules against enveloped viruses 63
The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis 63
Rhodanine derivatives as potent anti-HIV and anti-HSV microbicides 61
Nuovi inibitori reversibili della monoacilglicerolo lipasi (MAGL) quali potenziali agenti antitumorali, antiinfiammatori e neuroprotettivi. 61
Largazole Analogues as Histone Deacetylase Inhibitors and Anticancer Agents: An Overview of Structure–Activity Relationships 55
L-DOPA-quinone Mediated Recovery from GIRK Channel Firing Inhibition in Dopaminergic Neurons 55
null 51
Discovery of novel µ-opioid receptor inverse agonist from a combinatorial library of tetrapeptides through structure-based virtual screening 44
null 44
Consensus Docking in Drug Discovery 44
Three-dimensional interactions analysis of the anticancer target c-src kinase with its inhibitors 43
New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2 42
null 41
New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2 38
Discovery of monoacylglycerol lipase (MAGL) inhibitors based on a pharmacophore-guided virtual screening study 38
Mealworm (Tenebrio molitor): Potential and challenges to promote circular economy 36
Carbonic Anhydrase Inhibitors: Identifying Therapeutic Cancer Agents Through Virtual Screening 36
Monoacylglycerol lipase (MAGL) Inhibitors 36
Recent advances in in silico target fishing 31
null 30
Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design 29
From Anti-infective Agents to Cancer Therapy: a Drug Repositioning Study Revealed a New Use for Nitrofuran Derivatives 28
Dissecting the Activity of Catechins as Incomplete Aldose Reductase Differential Inhibitors through Kinetic and Computational Approaches 27
Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors 24
Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives 23
Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives 22
Virtual screening and crystallographic studies reveal an unexpected γ-lactone derivative active against MptpB as a potential antitubercular agent 22
New PIN1 inhibitors identified through a pharmacophore-driven, hierarchical consensus docking strategy 20
Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study 19
Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1H)-One Scaffold 16
Predicting potentially pathogenic effects of hRPE65 missense mutations: a computational strategy based on molecular dynamics simulations 14
Antibacterial alkylguanidino ureas: Molecular simplification approach, searching for membrane-based MoA 13
Nuovi agenti antivirali a struttura N-idrossiindrol-carbossamidica 12
VenomPred: A Machine Learning Based Platform for Molecular Toxicity Predictions 11
New Synthetic Analogues of Natural Polyphenols as Sirtuin 1-Activating Compounds 10
Co-Inhibition of P-gp and Hsp90 by an Isatin-Derived Compound Contributes to the Increase of the Chemosensitivity of MCF7/ADR-Resistant Cells to Doxorubicin 10
null 10
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety 9
Resveratrol Analogues as Dual Inhibitors of Monoamine Oxidase B and Carbonic Anhydrase VII: A New Multi-Target Combination for Neurodegenerative Diseases? 9
Monoacylglycerol lipase (MAGL) inhibitors based on a diphenylsulfide-benzoylpiperidine scaffold 8
Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system 8
Design, synthesis and biological evaluation of second-generation benzoylpiperidine derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors 6
Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study 5
An in silico toolbox for the prediction of the potential pathogenic effects of missense mutations in the dimeric region of hRPE65 5
Sirtuin 1-activating derivatives belonging to the anilinopyridine class displaying in vivo cardioprotective activities 5
A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration 4
Identification of New GSK3β Inhibitors through a Consensus Machine Learning-Based Virtual Screening 3
Development of a cheminformatics platform for selectivity analyses of carbonic anhydrase inhibitors 2
miRNA-203b-3p Induces Acute and Chronic Pruritus through 5-HTR2B and TRPV4 2
MolBook UNIPI─Create, Manage, Analyze, and Share Your Chemical Data for Free 1
Totale 5.958
Categoria #
all - tutte 18.612
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 18.612


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019263 0 0 0 0 0 0 0 0 0 0 152 111
2019/20201.425 107 99 86 110 136 166 139 128 140 111 84 119
2020/2021839 87 64 43 39 41 85 23 59 140 76 50 132
2021/2022913 46 45 26 63 123 142 33 46 52 46 46 245
2022/20231.041 131 162 110 74 83 118 30 74 154 11 54 40
2023/2024820 71 96 102 59 144 142 93 29 14 30 40 0
Totale 5.958