CINECA IRIS Institutional Research Information System

CICCONE, LIDIA
 Distribuzione geografica
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Continente #
NA - Nord America 2.442
EU - Europa 1.124
AS - Asia 616
AF - Africa 31
OC - Oceania 7
SA - Sud America 7
Continente sconosciuto - Info sul continente non disponibili 1
Totale 4.228
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Nazione #
US - Stati Uniti d'America 2.409
IT - Italia 515
SG - Singapore 253
CN - Cina 212
SE - Svezia 159
FR - Francia 107
DE - Germania 93
BG - Bulgaria 81
GB - Regno Unito 62
IN - India 44
CA - Canada 33
VN - Vietnam 32
RU - Federazione Russa 29
FI - Finlandia 20
HK - Hong Kong 20
TR - Turchia 18
JP - Giappone 13
NG - Nigeria 13
SN - Senegal 10
UA - Ucraina 10
PL - Polonia 8
BE - Belgio 7
KR - Corea 7
AT - Austria 6
AU - Australia 6
CH - Svizzera 6
NL - Olanda 6
IR - Iran 4
MA - Marocco 4
BR - Brasile 3
ES - Italia 3
IL - Israele 3
TW - Taiwan 3
AE - Emirati Arabi Uniti 2
CI - Costa d'Avorio 2
CO - Colombia 2
CZ - Repubblica Ceca 2
EE - Estonia 2
EG - Egitto 2
HR - Croazia 2
RO - Romania 2
BD - Bangladesh 1
BY - Bielorussia 1
CL - Cile 1
DK - Danimarca 1
EU - Europa 1
GR - Grecia 1
KH - Cambogia 1
MO - Macao, regione amministrativa speciale della Cina 1
NZ - Nuova Zelanda 1
OM - Oman 1
PT - Portogallo 1
TH - Thailandia 1
VE - Venezuela 1
Totale 4.228
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Città #
Santa Clara 392
Fairfield 227
Woodbridge 197
Singapore 153
Houston 146
Ashburn 133
Chandler 132
Ann Arbor 128
Serra 116
Boardman 95
New York 90
Cambridge 85
Seattle 84
Sofia 81
Wilmington 72
Milan 69
Princeton 59
Florence 55
Frankfurt am Main 51
Beijing 38
Lawrence 36
Medford 34
Pisa 32
Pessac 31
London 29
Ottawa 26
Redwood City 26
Ogden 24
Bures-sur-Yvette 23
San Diego 21
Hong Kong 19
Des Moines 17
Marseille 17
Pune 17
Dong Ket 16
Nanjing 16
Shanghai 16
Rome 15
Istanbul 14
Lagos 13
Bremen 12
Hangzhou 11
Talence 11
Dakar 10
Fuzhou 10
Dearborn 9
Los Angeles 9
Bengaluru 7
Dundee 7
Gif-sur-yvette 7
Lucca 7
San Francisco 7
Toronto 7
Jiaxing 6
Paris 6
Quanzhou 6
Vienna 6
Dallas 5
Naples 5
Norwalk 5
Tagliacozzo 5
Tokyo 5
Bern 4
Brussels 4
Cagliari 4
Capannoli 4
Cascina 4
Cerveteri 4
Guangzhou 4
Helsinki 4
Livorno 4
Malappuram 4
Ravenna 4
Warsaw 4
Washington 4
Calci 3
Castelliri 3
Changsha 3
Faggiano 3
Gainesville 3
Hebei 3
Hefei 3
Hyderabad 3
Jacksonville 3
Kunming 3
New Haven 3
Oxford 3
Phoenix 3
Pohang 3
Sassari 3
Shenyang 3
Sydney 3
Vicopisano 3
Volterra 3
Abidjan 2
Amsterdam 2
Armenia 2
Atlanta 2
Buffalo 2
Casablanca 2
Totale 3.129
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Nome #
Application of PROTAC strategy to TTR-Aβ protein-protein interaction for the development of Alzheimer’s disease drugs 230
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization 173
Copper mediated amyloid-β binding to Transthyretin 158
N-(aroyl)-N-(arylmethyloxy)-α-alanines: selective inhibitors of aldose reductase 157
Synthesis and cycloxygenase inhibitory properties of new naphthalene-methylsulfonamido, naphthalene-methylsulfonyl and tetrahydronaphthalen-methylsulfonamido compounds 135
Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies 129
Comparison of helical scan and standard rotation methods in single-crystal X-ray data collection strategies 124
Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors 121
Targeting Different Transthyretin Binding Sites with Unusual Natural Compounds 121
A new crystal form of human transthyretin obtained with a curcumin derived ligand 114
X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors 110
Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide 106
Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators 104
Exploring the binding of quercetin-3-O-metabolites with transthyretin 103
Cryoprotection and ligand solubilization: Evaluation of multicomponent mixtures 100
Transthyretin complexes with curcumin and bromo-estradiol: Evaluation of solubilizing multicomponent mixtures 98
Higher Crystallization Success Obtained for TTR-ligand Complexes Using a New Approach 95
Multicomponent mixtures for cryoprotection and ligand solubilization 95
Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR) 88
A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone 85
Oxy-imino saccharidic derivatives as a new structural class of aldose reductase inhibitors endowed with anti-oxidant activity 82
Human TTR conformation altered by rhenium tris-carbonyl derivatives 80
null 80
Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis 78
Synthesis and cycloxygenase inhibitory activity of new naphthalene-methylsulfonamido and naphthalene-methylsulfonyl compounds. 77
null 77
NEW CLASS OF INHIBITORS OF TTR AMYLOID FIBRIL FORMATION 75
Antioxidant quercetin 3-O-glycosylated plant flavonols contribute to Transthyretin stabilization 65
Natural marine and terrestrial compounds as modulators of matrix metalloproteinases-2 (MMP-2) and MMP-9 in alzheimer’s disease 60
Multifunctional Small Molecules as Potential Anti-Alzheimer's Disease Agents 57
Carbonic anhydrase inhibitors and epilepsy: State of the art and future perspectives 56
The positive side of the Alzheimer's disease amyloid cross-interactions: The case of the Aβ 1-42 peptide with tau, TTR, CysC, and ApoA1 53
Natural compounds as inhibitors of transthyretin amyloidosis and neuroprotective agents: analysis of structural data for future drug design 51
null 45
Physiological metals can induce conformational changes in transthyretin structure: Neuroprotection or misfolding induction? 43
Compounds with a benzo [a]carbazole structure for use in the prevention and/or treatment of infectious diseases 42
Neuroglobin and neuroprotection: The role of natural and synthetic compounds in neuroglobin pharmacological induction 37
Omega-3 PUFAs as a Dietary Supplement in Senile Systemic Amyloidosis 36
New isoxazolidinyl-based N-alkylethanolamines as new activators of human brain carbonic anhydrases 36
Inorganic Drugs as a Tool for Protein Structure Solving and Studies on Conformational Changes 34
Resveratrol-like Compounds as SIRT1 Activators 33
Identification of a Novel p53 Modulator Endowed with Antitumoural and Antibacterial Activity through a Scaffold Repurposing Approach 32
Protein Data Bank 6TJN (pdb) Human transthyretin (TTR) complexed with (E)-3-(((4-hydroxybenzylidene)amino)oxy)propanoic acid 31
Human transthyretin (TTR) complexed with Quercetin 3-O-beta-D-galactoside 27
New Hybrid Compounds Incorporating Natural Products as Multifunctional Agents against Alzheimer's Disease 27
Synthesis and Evaluation of Monoaryl Derivatives as Transthyretin Fibril Formation Inhibitors 26
Targeting Aggrecanases for Osteoarthritis Therapy: From Zinc Chelation to Exosite Inhibition 25
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated triazole-linked carboxylate chelator water-soluble inhibitor (DC32) 25
Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study 25
Nature-Inspired O-Benzyl Oxime-Based Derivatives as New Dual-Acting Agents Targeting Aldose Reductase and Oxidative Stress 25
Pterostilbene fluorescent probes as potential tools for targeting neurodegeneration in biological applications 25
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated triazole-linked carboxylate zinc-chelator water-soluble inhibitor (DC28) 24
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated arylsulfonamide carboxylate water-soluble inhibitor (DC27) 24
Pomegranate: A Source of Multifunctional Bioactive Compounds Potentially Beneficial in Alzheimer’s Disease 24
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated triazole-linked carboxylate chelating water-soluble inhibitor (DC24) 24
Discovery of Dimeric Arylsulfonamides as Potent ADAM8 Inhibitors 23
Tetrameric Transthyretin as a Protective Factor Against Alzheimer’s Disease 21
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated thiourea-linked carboxylate zinc-chelator water-soluble inhibitor (DC31) 21
Crystal structure of the catalytic domain of MMP-9 in complex with a selective sugar-conjugated arylsulfonamide carboxylate water-soluble inhibitor (DC27) 21
Crystal structure of a dimeric based inhibitor JG34 in complex with the MMP-12 catalytic domain 20
Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels 19
Structural and functional properties of the Kunitz-type and C-terminal domains of Amblyomin-X supporting its antitumor activity 19
Resveratrol Analogs and Prodrugs Differently Affect the Survival of Breast Cancer Cells Impairing Estrogen/Estrogen Receptor α/Neuroglobin Pathway 19
MT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries 19
Crystal structure of MMP12 in complex with inhibitor BE4 18
Dimolybdenum (II,II) paddlewheel complexes bearing non-steroidal anti-inflammatory drug ligands: Insights into the chemico-physical profile and first biological assessment 18
Crystal structure of MMP9 in complex with inhibitor BE4 17
Crystal structure of MMP12 in complex with inhibitor BE7 17
Human transthyretin (TTR) complexed with (R)-3-(9H-fluoren-9-ylideneaminooxy)-2-methyl-N-(methylsulfonyl) propionamide in a dual binding mode 16
Human transthyretin (TTR) complexed with (E)-3-(((3,5-dibromo-2-hydroxybenzylidene)amino)oxy)propanoic acid 16
Proteolytically Stable Diaza-Peptide Foldamers Mimic Helical Hot Spots of Protein-Protein Interactions and Act as Natural Chaperones 15
Human transthyretin (TTR) complexed with ferulic acid and curcumin 15
Complete PCSK9 C-ter domain in complex with VHH P1.40 15
Human transthyretin (TTR) complexed with (E)-3-(((4-hydroxybenzylidene)amino)oxy)propanoic acid 13
Crystal structure of toxin MT9 from mamba venom 13
A Snapshot of the Most Recent Transthyretin Stabilizers 11
UbiJ-SCP2 Ubiquinone synthesis protein 11
Human TTR altered conformation from soaking in iron chloride 11
UbiJ-SCP2 Ubiquinone synthesis protein 10
UbiJ-SCP2 Ubiquinone synthesis protein 9
Human TTR altered by a rhenium tris-carbonyl Pyta-C8 derivative 9
Human TTR crystals soaked in manganese chloride 9
Human TTR altered conformation from soaking in CuCl2 9
Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)ethanoic acid 9
Human transthyretin (TTR) complexed with curcumin 9
Human transthyretin (TTR) complexed with (2,7-Dibromo-fluoren-9-ylideneaminooxy)-acetic acid 9
Human transthyretin (TTR) complexed with (Z)-((3,4-Dichloro-phenyl)-methyleneaminooxy)-acetic acid 8
Human transthyretin (TTR) complexed with (2,7-Dichloro-fluoren-9-ylideneaminooxy)-acetic acid 8
Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid in a dual binding mode 8
Human transthyretin (TTR) complexed with 16-alpha-bromo-estradiol 8
null 7
Human TTR altered by a rhenium tris-carbonyl Pyta-C12 derivative 7
Dual binding mode for 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid binding to Human transthyretin (TTR) 7
Morpholine Prevents the Formation of Aspartimide from β-allyl ester aspartic acid during Fmoc Cleavage in SPPS of Stapled Peptides 5
Synthesis and characterization of divalent metal–betaine–bistriflimide complexes: a property comparison with metal bistriflimide salts 4
Totale 4.530
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Categoria #
all - tutte 15.940
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 15.940
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020293 0 0 0 0 0 56 49 46 49 32 32 29
2020/2021457 21 26 8 5 30 77 43 48 72 37 32 58
2021/2022638 17 134 19 20 82 79 34 33 26 8 43 143
2022/2023716 68 101 62 31 95 72 5 44 143 2 64 29
2023/2024648 57 46 55 32 128 100 46 12 12 10 88 62
2024/2025866 9 98 116 132 295 216 0 0 0 0 0 0
Totale 4.530