CINECA IRIS Institutional Research Information System

CICCONE, LIDIA
 Distribuzione geografica
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Continente #
NA - Nord America 4.333
AS - Asia 3.219
EU - Europa 1.701
SA - Sud America 574
AF - Africa 92
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 2
Totale 9.933
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Nazione #
US - Stati Uniti d'America 4.207
SG - Singapore 1.041
CN - Cina 848
IT - Italia 626
HK - Hong Kong 507
BR - Brasile 475
VN - Vietnam 253
DE - Germania 183
FR - Francia 181
SE - Svezia 174
GB - Regno Unito 133
JP - Giappone 118
IN - India 114
KR - Corea 95
BG - Bulgaria 83
RU - Federazione Russa 72
FI - Finlandia 71
CA - Canada 70
BD - Bangladesh 41
TR - Turchia 34
AR - Argentina 33
IQ - Iraq 30
MX - Messico 28
AT - Austria 27
NL - Olanda 25
PL - Polonia 25
UA - Ucraina 20
PK - Pakistan 19
ID - Indonesia 18
MA - Marocco 18
ES - Italia 17
ZA - Sudafrica 17
EC - Ecuador 16
NG - Nigeria 16
CO - Colombia 15
PE - Perù 12
CH - Svizzera 11
SN - Senegal 11
AU - Australia 10
SA - Arabia Saudita 10
TH - Thailandia 10
DK - Danimarca 8
PH - Filippine 8
VE - Venezuela 8
BE - Belgio 7
CZ - Repubblica Ceca 7
IL - Israele 7
JM - Giamaica 7
KE - Kenya 7
IR - Iran 6
NP - Nepal 6
EG - Egitto 5
HR - Croazia 5
KZ - Kazakistan 5
MY - Malesia 5
TW - Taiwan 5
AE - Emirati Arabi Uniti 4
AZ - Azerbaigian 4
BH - Bahrain 4
BO - Bolivia 4
CL - Cile 4
ET - Etiopia 4
JO - Giordania 4
OM - Oman 4
PA - Panama 4
TN - Tunisia 4
UY - Uruguay 4
UZ - Uzbekistan 4
BY - Bielorussia 3
CI - Costa d'Avorio 3
DO - Repubblica Dominicana 3
DZ - Algeria 3
HU - Ungheria 3
IE - Irlanda 3
KG - Kirghizistan 3
LB - Libano 3
LT - Lituania 3
PY - Paraguay 3
RO - Romania 3
TT - Trinidad e Tobago 3
BB - Barbados 2
CG - Congo 2
CR - Costa Rica 2
EE - Estonia 2
GR - Grecia 2
HN - Honduras 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
AL - Albania 1
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
DM - Dominica 1
EU - Europa 1
GT - Guatemala 1
JE - Jersey 1
KH - Cambogia 1
LV - Lettonia 1
ML - Mali 1
MM - Myanmar 1
Totale 9.922
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Città #
Singapore 595
Hong Kong 501
Ashburn 447
Santa Clara 400
Dallas 392
San Jose 326
Fairfield 227
Shanghai 211
Woodbridge 197
Hefei 152
Houston 152
Chandler 132
Ann Arbor 128
Serra 118
New York 116
Beijing 105
Tokyo 101
Boardman 99
Council Bluffs 99
Los Angeles 99
Seoul 88
Seattle 87
Cambridge 85
Milan 84
Sofia 82
Ho Chi Minh City 75
Wilmington 73
London 64
Florence 60
Frankfurt am Main 60
Princeton 59
Munich 56
Lauterbourg 43
São Paulo 43
Hanoi 41
Pisa 41
Redondo Beach 38
Buffalo 36
Lawrence 36
Medford 34
Helsinki 32
Pessac 29
Rome 27
Ottawa 26
Pune 26
Redwood City 26
Ogden 24
Bures-sur-Yvette 23
San Diego 22
Chicago 20
Orem 19
Rio de Janeiro 19
Istanbul 18
Des Moines 17
Marseille 17
Vienna 17
Columbus 16
Dong Ket 16
Nanjing 16
Nuremberg 16
Turku 16
Warsaw 16
Lucca 15
Baltimore 14
Brooklyn 14
Chennai 14
Elk Grove Village 14
Lagos 14
Toronto 14
Atlanta 13
Hangzhou 13
Bremen 12
Stockholm 12
Amsterdam 11
Brasília 11
Dakar 11
Dhaka 11
Haiphong 11
Salt Lake City 11
Talence 11
Baghdad 10
Curitiba 10
Da Nang 10
Fuzhou 10
Johannesburg 10
Paris 10
San Francisco 10
Belo Horizonte 9
Bengaluru 9
Dearborn 9
Denver 9
Düsseldorf 9
Guangzhou 9
Livorno 9
Abha 8
Atibaia 8
Jakarta 8
Lappeenranta 8
Poplar 8
Aarhus 7
Totale 6.646
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Nome #
Application of PROTAC strategy to TTR-Aβ protein-protein interaction for the development of Alzheimer’s disease drugs 324
N-(aroyl)-N-(arylmethyloxy)-α-alanines: selective inhibitors of aldose reductase 252
Targeting Different Transthyretin Binding Sites with Unusual Natural Compounds 232
Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies 220
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization 214
Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators 204
Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide 201
Copper mediated amyloid-β binding to Transthyretin 194
Synthesis and cycloxygenase inhibitory properties of new naphthalene-methylsulfonamido, naphthalene-methylsulfonyl and tetrahydronaphthalen-methylsulfonamido compounds 194
Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors 189
Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels 186
Antioxidant quercetin 3-O-glycosylated plant flavonols contribute to Transthyretin stabilization 186
Resveratrol-like Compounds as SIRT1 Activators 180
Exploring the binding of quercetin-3-O-metabolites with transthyretin 177
Targeting Aggrecanases for Osteoarthritis Therapy: From Zinc Chelation to Exosite Inhibition 168
Compounds with a benzo [a]carbazole structure for use in the prevention and/or treatment of infectious diseases 163
Synthesis and Evaluation of Monoaryl Derivatives as Transthyretin Fibril Formation Inhibitors 161
Oxy-imino saccharidic derivatives as a new structural class of aldose reductase inhibitors endowed with anti-oxidant activity 156
Omega-3 PUFAs as a Dietary Supplement in Senile Systemic Amyloidosis 154
New Hybrid Compounds Incorporating Natural Products as Multifunctional Agents against Alzheimer's Disease 151
A new crystal form of human transthyretin obtained with a curcumin derived ligand 151
Comparison of helical scan and standard rotation methods in single-crystal X-ray data collection strategies 150
X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors 149
Inorganic Drugs as a Tool for Protein Structure Solving and Studies on Conformational Changes 147
Pomegranate: A Source of Multifunctional Bioactive Compounds Potentially Beneficial in Alzheimer’s Disease 147
Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR) 147
Nature-Inspired O-Benzyl Oxime-Based Derivatives as New Dual-Acting Agents Targeting Aldose Reductase and Oxidative Stress 146
Proteolytically Stable Diaza-Peptide Foldamers Mimic Helical Hot Spots of Protein-Protein Interactions and Act as Natural Chaperones 142
Transthyretin complexes with curcumin and bromo-estradiol: Evaluation of solubilizing multicomponent mixtures 139
Natural marine and terrestrial compounds as modulators of matrix metalloproteinases-2 (MMP-2) and MMP-9 in alzheimer’s disease 139
Pterostilbene fluorescent probes as potential tools for targeting neurodegeneration in biological applications 138
Cryoprotection and ligand solubilization: Evaluation of multicomponent mixtures 138
Carbonic anhydrase inhibitors and epilepsy: State of the art and future perspectives 138
Higher Crystallization Success Obtained for TTR-ligand Complexes Using a New Approach 137
Multicomponent mixtures for cryoprotection and ligand solubilization 136
Multifunctional Small Molecules as Potential Anti-Alzheimer's Disease Agents 133
Human TTR conformation altered by rhenium tris-carbonyl derivatives 130
Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis 129
The positive side of the Alzheimer's disease amyloid cross-interactions: The case of the Aβ 1-42 peptide with tau, TTR, CysC, and ApoA1 128
Identification of a Novel p53 Modulator Endowed with Antitumoural and Antibacterial Activity through a Scaffold Repurposing Approach 121
NEW CLASS OF INHIBITORS OF TTR AMYLOID FIBRIL FORMATION 121
Neuroglobin and neuroprotection: The role of natural and synthetic compounds in neuroglobin pharmacological induction 120
Resveratrol Analogs and Prodrugs Differently Affect the Survival of Breast Cancer Cells Impairing Estrogen/Estrogen Receptor α/Neuroglobin Pathway 117
Cymodocea nodosa, a Promising Seagrass of Nutraceutical Interest: Overview of Phytochemical Constituents and Potential Therapeutic Uses 116
Tetrameric Transthyretin as a Protective Factor Against Alzheimer’s Disease 113
Structural and functional properties of the Kunitz-type and C-terminal domains of Amblyomin-X supporting its antitumor activity 113
A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone 113
A series of benzensulfonamide derivatives as new potent carbonic anhydrase IX and XII inhibitors 112
Synthesis and cycloxygenase inhibitory activity of new naphthalene-methylsulfonamido and naphthalene-methylsulfonyl compounds. 112
New isoxazolidinyl-based N-alkylethanolamines as new activators of human brain carbonic anhydrases 111
Natural compounds as inhibitors of transthyretin amyloidosis and neuroprotective agents: analysis of structural data for future drug design 106
A Snapshot of the Most Recent Transthyretin Stabilizers 102
Human transthyretin (TTR) complexed with Quercetin 3-O-beta-D-galactoside 102
Discovery of a new ATP-citrate lyase (ACLY) inhibitor identified by a pharmacophore-based virtual screening study 100
Discovery of Dimeric Arylsulfonamides as Potent ADAM8 Inhibitors 97
Physiological metals can induce conformational changes in transthyretin structure: Neuroprotection or misfolding induction? 97
Dimolybdenum (II,II) paddlewheel complexes bearing non-steroidal anti-inflammatory drug ligands: Insights into the chemico-physical profile and first biological assessment 89
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Morpholine Prevents the Formation of Aspartimide from β-allyl ester aspartic acid during Fmoc Cleavage in SPPS of Stapled Peptides 79
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Crystal structure of a dimeric based inhibitor JG34 in complex with the MMP-12 catalytic domain 76
Protein Data Bank 6TJN (pdb) Human transthyretin (TTR) complexed with (E)-3-(((4-hydroxybenzylidene)amino)oxy)propanoic acid 69
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated arylsulfonamide carboxylate water-soluble inhibitor (DC27) 66
Synthesis and characterization of divalent metal–betaine–bistriflimide complexes: a property comparison with metal bistriflimide salts 64
Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines 60
Human TTR altered conformation from soaking in iron chloride 58
Crystal structure of the catalytic domain of MMP-9 in complex with a selective sugar-conjugated arylsulfonamide carboxylate water-soluble inhibitor (DC27) 56
MT9, a natural peptide from black mamba venom antagonizes the muscarinic type 2 receptor and reverses the M2R-agonist-induced relaxation in rat and human arteries 54
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated triazole-linked carboxylate chelating water-soluble inhibitor (DC24) 52
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated triazole-linked carboxylate chelator water-soluble inhibitor (DC32) 49
Crystal structure of MMP12 in complex with inhibitor BE4 49
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated triazole-linked carboxylate zinc-chelator water-soluble inhibitor (DC28) 48
Crystal structure of toxin MT9 from mamba venom 47
Crystal structure of the catalytic domain of MMP-12 in complex with a selective sugar-conjugated thiourea-linked carboxylate zinc-chelator water-soluble inhibitor (DC31) 47
null 45
Crystal structure of MMP12 in complex with inhibitor BE7 43
Human transthyretin (TTR) complexed with (E)-3-(((3,5-dibromo-2-hydroxybenzylidene)amino)oxy)propanoic acid 41
Crystal structure of MMP9 in complex with inhibitor BE4 40
Complete PCSK9 C-ter domain in complex with VHH P1.40 33
Human TTR crystals soaked in manganese chloride 31
Human transthyretin (TTR) complexed with ferulic acid and curcumin 31
Human transthyretin (TTR) complexed with (E)-3-(((4-hydroxybenzylidene)amino)oxy)propanoic acid 30
Human TTR altered conformation from soaking in CuCl2 30
UbiJ-SCP2 Ubiquinone synthesis protein 29
Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)ethanoic acid 29
UbiJ-SCP2 Ubiquinone synthesis protein 27
Human transthyretin (TTR) complexed with (R)-3-(9H-fluoren-9-ylideneaminooxy)-2-methyl-N-(methylsulfonyl) propionamide in a dual binding mode 27
Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid in a dual binding mode 27
UbiJ-SCP2 Ubiquinone synthesis protein 25
Human TTR altered by a rhenium tris-carbonyl Pyta-C8 derivative 25
Human transthyretin (TTR) complexed with (Z)-((3,4-Dichloro-phenyl)-methyleneaminooxy)-acetic acid 24
Human transthyretin (TTR) complexed with (2,7-Dibromo-fluoren-9-ylideneaminooxy)-acetic acid 24
Human transthyretin (TTR) complexed with curcumin 23
Human TTR altered by a rhenium tris-carbonyl Pyta-C12 derivative 22
Human transthyretin (TTR) complexed with (2,7-Dichloro-fluoren-9-ylideneaminooxy)-acetic acid 21
Human transthyretin (TTR) complexed with 16-alpha-bromo-estradiol 21
Dual binding mode for 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid binding to Human transthyretin (TTR) 20
From simple to complex: multiscale modeling of metal-mediated protein interactions to uncover mechanistic insights into the action of inorganic drugs 16
Profiling plasma transthyretin in healthy subjects and patients with cardiac ATTR amyloidosis by native electrophoresis 14
Current Standards and Perspectives in Proteomics for Cardiac Amyloidosis 12
Totale 10.274
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Categoria #
all - tutte 29.802
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 29.802
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202190 0 0 0 0 0 0 0 0 0 0 32 58
2021/2022638 17 134 19 20 82 79 34 33 26 8 43 143
2022/2023716 68 101 62 31 95 72 5 44 143 2 64 29
2023/2024640 57 46 55 32 127 98 45 12 12 10 84 62
2024/20252.963 9 97 115 130 291 273 296 128 344 283 381 616
2025/20263.662 268 542 502 421 350 236 481 146 293 342 81 0
Totale 10.281