CINECA IRIS Institutional Research Information System

ORLANDI, PAOLA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 5.995
EU - Europa 2.334
AS - Asia 1.278
SA - Sud America 121
AF - Africa 115
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 2
AN - Antartide 1
Totale 9.853
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 5.896
IT - Italia 809
CN - Cina 553
SE - Svezia 422
SG - Singapore 378
DE - Germania 342
BG - Bulgaria 187
GB - Regno Unito 135
BR - Brasile 103
VN - Vietnam 97
CA - Canada 95
HK - Hong Kong 85
TR - Turchia 83
RU - Federazione Russa 77
FI - Finlandia 73
CI - Costa d'Avorio 67
UA - Ucraina 67
AT - Austria 51
FR - Francia 43
IN - India 37
BE - Belgio 27
CH - Svizzera 26
NG - Nigeria 23
SN - Senegal 18
PL - Polonia 17
NL - Olanda 12
AU - Australia 7
CZ - Repubblica Ceca 7
DK - Danimarca 7
EC - Ecuador 7
IR - Iran 7
CO - Colombia 4
GR - Grecia 4
HU - Ungheria 4
IE - Irlanda 4
JP - Giappone 4
LT - Lituania 4
NO - Norvegia 4
PK - Pakistan 4
AR - Argentina 3
ES - Italia 3
IQ - Iraq 3
KR - Corea 3
PH - Filippine 3
RO - Romania 3
UZ - Uzbekistan 3
VE - Venezuela 3
AM - Armenia 2
AZ - Azerbaigian 2
BJ - Benin 2
JO - Giordania 2
MA - Marocco 2
MX - Messico 2
MY - Malesia 2
RS - Serbia 2
ZA - Sudafrica 2
A1 - Anonimo 1
BA - Bosnia-Erzegovina 1
BN - Brunei Darussalam 1
CL - Cile 1
CY - Cipro 1
DO - Repubblica Dominicana 1
EE - Estonia 1
EU - Europa 1
GS - Georgia del Sud e Isole Sandwich Australi 1
ID - Indonesia 1
IL - Israele 1
KH - Cambogia 1
LB - Libano 1
MD - Moldavia 1
NI - Nicaragua 1
NP - Nepal 1
PT - Portogallo 1
SA - Arabia Saudita 1
TH - Thailandia 1
TN - Tunisia 1
TW - Taiwan 1
Totale 9.853
Salva come PNG Salva come JPEG
Città #
Woodbridge 833
Fairfield 612
Ann Arbor 603
Chandler 458
Houston 456
Santa Clara 412
Ashburn 324
Seattle 303
Wilmington 255
Cambridge 231
Serra 217
Sofia 187
Shanghai 182
Singapore 135
New York 131
Milan 130
Beijing 111
Boardman 109
Ottawa 85
Princeton 84
Hong Kong 83
Lawrence 75
Medford 69
Abidjan 67
Jacksonville 62
Dong Ket 60
Des Moines 58
Dearborn 53
Izmir 49
Pisa 47
Vienna 45
Florence 41
Nanjing 38
London 37
Rome 34
Istanbul 31
Ogden 31
Boulder 29
Brussels 27
San Diego 27
Frankfurt am Main 25
Los Angeles 25
Falls Church 24
Fuzhou 24
Bremen 23
Düsseldorf 23
Lagos 23
Nanchang 23
Bern 20
Marseille 19
Dakar 18
Helsinki 18
Redwood City 18
Pune 15
Warsaw 15
Nürnberg 14
Munich 13
Quanzhou 13
Rho 12
Shenyang 12
Council Bluffs 11
Hebei 11
Kunming 11
Norwalk 11
Vicopisano 11
Jüchen 10
Lancaster 10
Lucca 10
Seacroft 10
Auburn Hills 8
Phoenix 8
Dallas 7
Dülmen 7
Jiaxing 7
Sezze 7
São Paulo 7
Guangzhou 6
Hangzhou 6
Rio de Janeiro 6
Toronto 6
Belo Horizonte 5
Calci 5
Changsha 5
Hefei 5
Quito 5
Shirvan 5
Tianjin 5
Amsterdam 4
Brno 4
Budapest 4
Chongqing 4
Copenhagen 4
Indiana 4
Moscow 4
Nuremberg 4
Palo del Colle 4
Shenzhen 4
Tappahannock 4
Washington 4
Xiamen 4
Totale 7.455
Salva come PNG Salva come JPEG
Nome #
1,2-Benzisothiazole Derivatives Bearing 4-, 5-, or 6-Alkyl/arylcarboxamide Moieties Inhibit Carbonic Anhydrase Isoform IX (CAIX) and Cell Proliferation under Hypoxic Conditions 343
VEGF-A polymorphisms predict short-term functional response to intravitreal ranibizumab in exudative age-related macular degeneration 209
Association of Glutathione S-Transferase P-1 (GSTP-1) rs1695 polymorphism with overall survival in glioblastoma patients treated with combined radio-chemotherapy 208
A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients. 202
Antiproliferative and Proapoptotic Activity of Sunitinib on Endothelial and Anaplastic Thyroid Cancer Cells via Inhibition of Akt and ERK1/2 Phosphorylation and by Down-Regulation of Cyclin-D1. 201
Pharmacogenetic interaction analysis of VEGFR-2 and IL-8 polymorphisms in advanced breast cancer patients treated with paclitaxel and bevacizumab. 194
CLM29, a multi-target pyrazolopyrimidine derivative, has anti-neoplastic activity in medullary thyroid cancer in vitro and in vivo 180
First-line metronomic chemotherapy in a metastatic model of spontaneous canine tumours: a pilot study 178
Clinical, pharmacodynamic and pharmacokinetic results of a prospective phase II study on oral metronomic vinorelbine and dexamethasone in castration-resistant prostate cancer patients 175
EGFR ligands as pharmacodynamic biomarkers in metastatic colorectal cancer patients treated with cetuximab and irinotecan 174
Clinical, pharmacokinetic and pharmacodynamic evaluations of metronomic UFT and cyclophosphamide plus celecoxib in patients with advanced refractory gastrointestinal cancers 167
Association of XRCC3 rs1799794 polymorphism with survival of glioblastoma multiforme patients treated with combined radio-chemotherapy 161
Pharmacogenetics of antiangiogenic and antineovascular therapies of age-related macular degeneration. 158
The rs2071559 AA VEGFR-2 genotype frequency is significantly lower in neovascular age-related macular degeneration patients. 157
Vandetanib has antineoplastic activity in anaplastic thyroid cancer, in vitro and in vivo 157
Gender, MGMT methylation, and levetiracetam plasma levels correlate with survival benefit in glioblastoma patients treated with adjuvant temozolomide: results from a non-interventional retrospective clinical study 157
Docetaxel plus oral metronomic cyclophosphamide: A phase II study with pharmacodynamic and pharmacogenetic analyses in castration-resistant prostate cancer patients 155
Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer. 154
Exploratory analysis of circulating pro-and anti-angiogenic factors in metastatic colorectal cancer (MCRC) patients, treated with GONO-folfoxiri plus bevacizumab (BV) 141
Structure-Based Optimization of Tyrosine Kinase Inhibitor CLM3. Design, Synthesis, Functional Evaluation, and Molecular Modeling Studies. 141
Melanocortin Receptor-4 Gene Polymorphisms in Glioblastoma Patients Treated with Concomitant Radio-Chemotherapy 139
Lenvatinib exhibits antineoplastic activity in anaplastic thyroid cancer in vitro and in vivo 139
Circulating amphiregulin (AR) plasma levels as surrogate pharmacodynamic markers of EGFR inhibition with cetuximab in metastatic colorectal cancer (MCRC) patients 138
Melanocortin Receptor-4 and Glioblastoma Cells: Effects of the Selective Antagonist ML00253764 Alone and in Combination with Temozolomide In Vitro and In Vivo 137
Low-dose metronomic cyclophosphamide plus celecoxib and dexamethasone in advanced hormone refractory prostate cancer (HRPC): a phase II clinical trial with evaluation of clinical, biologic and pharmacodynamic effects of the combination 136
Investigation of new 2-aryl substituted Benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors targeting vascular endothelial growth factor receptor 2 136
Phase II clinical trial of metronomic cyclophosphamide (CTX) plus celecoxib ( C ) and dexamethasone (DEX) in advanced hormone refractory prostate cancer (HRPC): preliminary clinical and pharmacodynamic results 134
Circulating angiogenic factors as predictors of benefit from bevacizumab (bev) beyond progression in metastatic colorectal cancer (mCRC): Translational analyses from the phase III BEBYP trial. 134
Discordant somatic and germline VEGF-A genotype in a cancer patient resistant to paclitaxel/bevacizumab with chemosensitive hepatic metastasis. 128
Chemotherapeutic and antiangiogenic drugs beyond tumor progression in colon cancer: evaluation of the effects of switched schedules and related pharmacodynamics 128
null 127
Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo. 126
In vitro antiangiogenic activity of selective somatostatin subtype-1 receptor agonists 123
Dual Kit/Aur Inhibitors as Chemosensitizing Agents for the Treatment of Melanoma: Design, Synthesis, Docking Studies and Functional Investigation 123
Antiproliferative and proapoptotic activity of CLM3, a novel multiple tyrosine kinase inhibitor, alone and in combination with SN-38 on endothelial and cancer cells 121
Fluvastatin synergistically enhances the antiproliferative effect of gemcitabine in human pancreatic cancer MIAPaCa-2 cells 118
Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib 116
Metronomic cyclophosphamide in elderly patients with advanced, castration-resistant prostate cancer 115
Clinical and pharmacodynamic evaluation of metronomic cyclophosphamide, celecoxib, and dexamethasone in advanced hormone-refractory prostate cancer 115
In vitro and in vivo antitumour effects of novel, orally active bile acid-conjugated platinum complexes on rat hepatoma 114
null 114
Overexpression and functional relevance of somatostatin receptor-1, -2, and -5 in endometrium and endometriotic lesions 112
Polymorphisms interaction to predict bevacizumab (BV) efficacy in metastatic breast cancer (MBC) patients: an exploratory retrospective analysis. 110
IL-8 and VEGFR-2 polymorphisms modulate long-term functional response to intravitreal ranibizumab in exudative age-related macular degeneration 110
Irinotecan Metronomic Chemotherapy (MC) in patients with diagnosis of metastatic colorectal cancer (MCRC): clinical, pharmacodynamic (PD) and pharmacokinetic (PK) evaluation 107
Prevention of capecitabine toxicity using a 5-FU test dose 106
Pilot study of correlation between single nucleotide polymorphisms (SNPS) of pro-and anti-angiogenic genes and response to bevacizumab (BV) plus chemotherapy (CT) in patients with metastatic breast cancer (MBC) 106
Metronomic chemotherapy (MC) with irinotecan (CPT-11) in patients with diagnosis of metastatic colorectal cancer (MCRC): clinical, pharmacodynamic (PD) and pharmacokinetic (PK) evaluation. Final report 103
Genetic interaction analysis of VEGF-A rs3025039 and VEGFR-2 rs2071559 identifies a genetic profile at higher risk to develop nodular goiter 103
Pharmacological effects of the simultaneous and sequential combinations of trifluridine/tipiracil (TAS-102) and 5-fluorouracil in fluoropyrimidine-sensitive colon cancer cells 103
A new biometric tool for three-dimensional subcutaneous tumor scanning in mice. 101
Pharmacokinetic analysis of metronomic capecitabine in refractory metastatic colorectal cancer patients 101
null 101
Prospective analysis of the early modulation of plasma amphiregulin (AR) during treatment with cetuximab and irinotecan in irinotecan-refractory metastatic colorectal cancer (mCRC) patients (pts). 97
Metronomic chemotherapy (MC) with irinotecan (CPT-11) in patients with diagnosis of metastatic colorectal cancer (MCRC): clinical and pharmacodynamic evaluation 95
Polymorphisms interaction to predict bevacizumab (BV) efficacy in metastatic breast cancer (MBC) patients (pts): An exploratory retrospective analysis. 95
Metronomic ceramide analogs inhibit angiogenesis in pancreatic cancer through up-regulation of caveolin-1 and thrombospondin-1 and down-regulation of cyclin D1 95
Idarubicin and idarubicinol effects on breast cancer multicellular spheroids 92
Metronomic vinorelbine is directly active on Non Small Cell Lung Cancer cells and sensitizes the EGFRL858R/T790M cells to reversible EGFR tyrosine kinase inhibitors 91
Synergistic efficacy of irinotecan and sunitinib combination in preclinical models of anaplastic thyroid cancer 90
Vascular endothelial growth factor-A (VEGF-A) single nucleotide polymorphisms and endometriosis: still a controversial issue 89
Metronomic capecitabine (cape) and cyclophosphamide (CTX) for refractory metastatic colorectal cancer (mCRC): Results of a phase II trial. 89
null 89
Phase II clinical trial with pharmacodynamic evaluation of docetaxel/prednisone plus metronomic cyclophosphamide and celecoxib as first line treatment in metastatic hormone refractory prostate cancer (MHRPC) 87
Agenti melanocortinici per l’impiego nel trattamento terapeutico del melanoma, dei tumori del tratto gastroenterico e del carcinoma tiroideo 83
Pharmacological effects of vinorelbine in combination with lenvatinib in anaplastic thyroid cancer 81
Gender, MGMT methylation, and levetiracetam plasma levels correlate with survival benefit in glioblastoma patients treated with adjuvant temozolomide: results from a non-interventional retrospective clinical study 81
Active metronomic vinorelbine schedules decrease plasma interleukin-2 levels in mice with Lewis lung carcinoma 80
null 76
Synergistic activity of linifanib and irinotecan increases the survival of mice bearing orthotopically implanted human anaplastic thyroid cancer 75
All-oral metronomic DEVEC schedule in elderly patients with peripheral T cell lymphoma 73
Polimorfismi genetici del VEGF e DMLE 72
Antiangiogenic drugs in NASH: Evidence of a possible new therapeutic approach 71
Effects of Pazopanib Monotherapy vs. Pazopanib and Topotecan Combination on Anaplastic Thyroid Cancer Cells 70
MELANOCORTIN AGENTS FOR USE IN THE THERAPEUTIC TREATMENT OF MELANOMA, TUMORS OF THE GASTROINTESTINAL TRACT, AND THYROID CARCINOMA 68
Old and New Systemic Immune-Inflammation Indexes Are Associated with Overall Survival of Glioblastoma Patients Treated with Radio-Chemotherapy 65
Preclinical and clinical combination therapies in the treatment of anaplastic thyroid cancer 61
Early increase of plasma soluble VEGFR-2 is associated with clinical benefit from second-line treatment of paclitaxel and ramucirumab in advanced gastric cancer 59
Aflibercept administration in neovascular age-related macular degeneration refractory to previous anti-vascular endothelial growth factor drugs: a critical review and new possible approaches to move forward 56
VEGF-A polymorphisms predict progression-free survival among advanced castration-resistant prostate cancer patients treated with metronomic cyclophosphamide. 55
Genetic interaction of P2X7 receptor and VEGFR-2 polymorphisms identifies a favorable prognostic profile in prostate cancer patients 53
A pharmacogenetic interaction analysis of bevacizumab with paclitaxel in advanced breast cancer patients 53
Correction to: Association of XRCC3 rs1799794 polymorphism with survival of glioblastoma multiforme patients treated with combined radio-chemotherapy 46
null 46
Simultaneous, But Not Consecutive, Combination With Folinate Salts Potentiates 5-fluorouracil Antitumor Activity In Vitro and In Vivo 44
Pharmacodynamic and pharmacogenetic angiogenesis-related markers of first-line FOLFOXIRI plus bevacizumab schedule in metastatic colorectal cancer 36
Melanocortin receptor 4 as a new target in melanoma therapy: Anticancer activity of the inhibitor ML00253764 alone and in association with B-raf inhibitor vemurafenib 30
Remarkable Remission Rate and Long-Term Efficacy of Upfront Metronomic Chemotherapy in Elderly and Frail Patients, with Diffuse Large B-Cell Lymphoma 26
Discovery of a Potent Dual Inhibitor of Aromatase and Aldosterone Synthase 25
Predictive Power of Tissue and Circulating Biomarkers for the Severity of Biopsy-Validated Chronic Liver Diseases 23
Metronomic Chemotherapy in Elderly Patients 20
Association of plasma levetiracetam concentration, MGMT methylation and sex with survival of chemoradiotherapy-treated glioblastoma patients 14
Melanocortin-4 Receptor Antagonism Inhibits Colorectal and Anaplastic Thyroid Cancer In Vitro and In Vivo 6
Totale 10.093
Salva come PNG Salva come JPEG
Categoria #
all - tutte 28.748
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.748
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020461 0 0 0 0 0 0 0 0 189 112 123 37
2020/2021839 66 85 58 35 88 35 30 92 96 82 51 121
2021/2022917 14 71 21 32 154 154 26 34 53 40 54 264
2022/20231.467 175 223 126 128 158 187 9 104 259 6 80 12
2023/2024850 82 97 93 56 101 167 26 48 18 22 53 87
2024/20251.588 17 114 43 192 302 325 228 126 241 0 0 0
Totale 10.093