CINECA IRIS Institutional Research Information System

TONACCHERA, MASSIMO
 Distribuzione geografica
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Continente #
NA - Nord America 15.942
AS - Asia 7.229
EU - Europa 4.667
SA - Sud America 965
AF - Africa 322
OC - Oceania 23
Continente sconosciuto - Info sul continente non disponibili 6
Totale 29.154
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Nazione #
US - Stati Uniti d'America 15.505
SG - Singapore 2.169
CN - Cina 2.065
IT - Italia 1.127
HK - Hong Kong 1.115
BR - Brasile 793
SE - Svezia 735
VN - Vietnam 686
DE - Germania 578
BG - Bulgaria 500
CA - Canada 351
TR - Turchia 337
GB - Regno Unito 318
FR - Francia 265
FI - Finlandia 237
UA - Ucraina 233
RU - Federazione Russa 219
KR - Corea 164
IN - India 147
CI - Costa d'Avorio 144
AT - Austria 127
BD - Bangladesh 89
CH - Svizzera 85
JP - Giappone 83
PK - Pakistan 60
AR - Argentina 56
IQ - Iraq 56
NL - Olanda 44
IE - Irlanda 43
SN - Senegal 41
MX - Messico 37
SA - Arabia Saudita 37
ZA - Sudafrica 34
ID - Indonesia 33
PL - Polonia 31
BE - Belgio 28
EC - Ecuador 28
ES - Italia 28
MY - Malesia 25
VE - Venezuela 22
UZ - Uzbekistan 21
NG - Nigeria 17
AU - Australia 16
KE - Kenya 16
PY - Paraguay 16
CO - Colombia 14
GR - Grecia 13
OM - Oman 13
PH - Filippine 13
JO - Giordania 12
CZ - Repubblica Ceca 11
MA - Marocco 11
NP - Nepal 11
PE - Perù 11
TT - Trinidad e Tobago 11
UY - Uruguay 11
CL - Cile 10
AE - Emirati Arabi Uniti 9
BJ - Benin 9
EG - Egitto 9
KZ - Kazakistan 9
TN - Tunisia 9
LB - Libano 8
AL - Albania 7
ET - Etiopia 7
IL - Israele 7
LT - Lituania 7
NZ - Nuova Zelanda 7
DZ - Algeria 6
SY - Repubblica araba siriana 6
AZ - Azerbaigian 5
BH - Bahrain 5
IR - Iran 5
JM - Giamaica 5
PS - Palestinian Territory 5
QA - Qatar 5
RO - Romania 5
BB - Barbados 4
CR - Costa Rica 4
GE - Georgia 4
AM - Armenia 3
DK - Danimarca 3
DO - Repubblica Dominicana 3
EU - Europa 3
KG - Kirghizistan 3
LY - Libia 3
MM - Myanmar 3
NI - Nicaragua 3
NO - Norvegia 3
PT - Portogallo 3
RS - Serbia 3
TH - Thailandia 3
TW - Taiwan 3
VC - Saint Vincent e Grenadine 3
BF - Burkina Faso 2
BM - Bermuda 2
BO - Bolivia 2
BS - Bahamas 2
BW - Botswana 2
CY - Cipro 2
Totale 29.103
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Città #
Woodbridge 1.827
Ashburn 1.529
Fairfield 1.387
Singapore 1.247
Ann Arbor 1.208
Houston 1.144
Hong Kong 1.101
Chandler 922
Santa Clara 683
Dallas 629
San Jose 616
Seattle 591
Wilmington 508
Sofia 496
Shanghai 444
Cambridge 431
Beijing 389
New York 332
Ottawa 295
Milan 282
Jacksonville 279
Boardman 231
Hefei 213
Princeton 203
Izmir 201
Los Angeles 195
Lawrence 192
Medford 175
Ho Chi Minh City 172
Seoul 163
Lauterbourg 158
Nanjing 154
Abidjan 144
Des Moines 125
Serra 113
Hanoi 112
Munich 110
Vienna 106
Florence 98
Istanbul 91
Menlo Park 89
Bern 84
Buffalo 77
Redondo Beach 73
Tokyo 69
Boulder 67
Dong Ket 67
Nanchang 65
São Paulo 61
Jüchen 57
Frankfurt am Main 55
Columbus 53
San Diego 53
Council Bluffs 48
Dearborn 48
Falls Church 48
The Dalles 48
Kunming 44
Lahore 44
Dakar 41
Helsinki 41
Cascina 40
Pisa 40
Rome 36
Detroit 34
Marseille 34
Hebei 33
London 33
Shenyang 33
Düsseldorf 32
Ogden 30
Redwood City 30
Fuzhou 28
Turku 27
Changsha 26
Orem 26
Rio de Janeiro 26
Brussels 25
Chicago 25
Guangzhou 25
Jinan 23
Amsterdam 22
Lancaster 22
Tianjin 22
Bremen 21
Dhaka 21
Nuremberg 21
Phoenix 21
Baghdad 20
Brasília 20
Haiphong 20
Hangzhou 20
Washington 20
Da Nang 19
Jiaxing 19
Riyadh 19
Atlanta 18
Ningbo 18
Tashkent 18
Johannesburg 17
Totale 21.512
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Nome #
The role of nuclear medicine in the clinical management of benign thyroid disorders. Part 1. Hyperthyroidism 338
Identification of a novel pax8 gene sequence variant in four members of the same family: from congenital hypothyroidism with thyroid hypoplasia to mild subclinical hypothyroidism. 262
Presence in the pre-surgical fine-needle aspiration of potential thyroid biomarkers previously identified in the post-surgical one. 240
Proteomic analysis of fine-needle aspiration in differential diagnosis of thyroid nodules. 229
In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity 215
uptake of amiodarone by thyroidal and non-thyroidal cell lines 214
Iodine contributes to thyroid autoimmunity in humans by unmasking a cryptic epitope on thyroglobulin. 212
Somatic and germline mutations of the TSH receptor gene in thyroid diseases 211
A Combined Therapy with Myo-Inositol and D-Chiro-Inositol Improves Endocrine Parameters and Insulin Resistance in PCOS Young Overweight Women 209
Absence of interference of serum IgGs from patients with breast cancer and thyroid autoimmunity on the function of human iodide symporter gene stably transfected in CHO cells 207
STUDY OF POTENTIAL INHIBITORS OF THYROID IODIDE UPTAKE BY USING CHO CELLS STABLY EXPRESSING THE HUMAN SODIUM/IODIDE SYMPORTER (hNIS) PROTEIN 199
Effects of a thyroid-stimulating human monoclonal autoantibody (M22) on functional activity of LH and FSH receptors 197
Absence of interference of serum IgGs from patients with breast cancer and thyroid autoimmunity on the function of human iodide symporter gene stably transfected in CHO cells 193
Genetic mutations in the treatment of anaplastic thyroid cancer: a systematic review. 191
A large-scale association study to assess the impact of known variants of the human INHA gene on premature ovarian failure 191
The thyroperoxidase doublet is not produced by alternative splicing 190
Electric and magnetic fields do not modify the biochemical properties of FRTL-5 cells 190
Evaluation of l-thyroxine replacement therapy in children with congenital hypothyroidism 189
Expression of IP-10/CXCL10 and MIG/CXCL9 in the thyroid and increased levels of IP-10/CXCL10 in the serum of patients with recent-onset Graves' disease 187
Agretti P, De Marco G, De Servi M, Marcocci C, Vitti P, Pinchera A, Tonacchera M.: Evidence for protein and mRNA TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy (TAO) after adipocytic differentiation 186
The large majority of 1520 patients with indeterminate thyroid nodule at cytology have a favorable outcome, and a clinical risk score has a high negative predictive value for a more cumbersome cancer disease. 186
Iodine nutrition status, thyroid function in the first trimester of pregnancy and pregnancy progression in women residing in an area of know moderate iodine deficiency 186
TSH receptor antibodies do not alter the function of gonadotropin receptors stably expressed in eukaryotic cells 184
Activating thyrotropin receptor mutations are present in nonadenomatous hyperfunctioning nodules of toxic or autonomous multinodular goiter 183
Differential effects of NaCl concentration on the constitutive activity of the thyrotropin and the luteinizing hormone/chorionic gonadotropin receptors 182
High risk of congenital hypothyroidism in multiple pregnancies 182
Mapping thyroid peroxidase epitopes using recombinant protein fragments 181
Activating thyrotropin receptor mutations in histologically heterogeneous hyperfunctioning nodules of multinodular goiter. 181
Gonadotrophin receptor blocking antibodies measured by the use of cell lines stably expressing human gonadotrophin receptors are not detectable in women with 46,XX premature ovarian failure 181
Iodine deficiency from pregnancy to childhood 181
Patients with indeterminate thyroid nodules at cytology and cancer at histology have a more favourable outcome with respect to patients with suspicious or malignant cytology 180
Screening for drugs potentially interfering with MCT8-mediated T 3 transport in vitro identifies dexamethasone and some commonly used drugs as inhibitors of MCT8 activity 178
Diagnostic utility of BRAFV600E mutation testing in thyroid nodules in elderly patients. 177
Functioning and non functioning thyroid adenomas involve different molecular pathogenetic mechanisms 177
The G protein-coupled receptor family and one of its members, the TSH receptor 176
Constitutively active receptors as a disease-causing mechanism 176
Blood cell mitochondrial DNA content and premature ovarian aging. 176
Identification and functional studies of two new dual-oxidase 2 (DUOX2) mutations in a child with congenital hypothyroidism and a eutopic normal-size thyroid gland 173
GENETIC MARKERS TO DISCRIMINATE BENIGN AND MALIGNANT THYROID NODULES WITH UNDETERMINED CYTOLOGY IN AN AREA OF BORDERLINE IODINE DEFICIENCY. 173
Patients with Indeterminate Thyroid Nodules at Cytology and Cancer at Histology Have a More Favorable Outcome Compared with Patients with Suspicious or Malignant Cytology 173
Detection of circulating autoantibodies against thyroid hormones in an infant with permanent congenital hypothyroidism and her twin with transient congenital hypothyroidism: possible contribution of thyroid hormone autoantibodies to neonatal and infant hypothyroidism 172
Assessment of nodular goitre 172
Markers of cell proliferation, apoptosis, and angiogenesis in thyroid adenomas: a comparative immunohistochemical and genetic investigation of functioning and nonfunctioning nodules 171
Autoantibodies from patients with autoimmune thyroid disease do not interfere with the activity of the human iodide symporter gene stably transfected in CHO cells. 170
A Fast Method to Detect Cell Surface Expression of Thyrotropin Receptor (TSHr): The Microchip Flow Cytometry Analysis 170
Evidences for an allelic variant of the human LC/CG receptor rather than a gene duplication: functional comparison of wild-type and variant receptors 169
Low prevalence of thyrotropin receptor mutations in a large series of subjects with sporadic and familial nonautoimmune subclinical hypothyroidism 169
The way forward in Italy for iodine 168
Iodine fortification of vegetables improves human iodine nutrition: In vivo evidence for a new model of iodine prophylaxis 168
Genetic interaction analysis of VEGF-A rs3025039 and VEGFR-2 rs2071559 identifies a genetic profile at higher risk to develop nodular goiter 168
Cloning of candidate autoantigen carboxypeptidase H from a human islet library: sequence identity with human brain CPH 167
Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid 166
Metabolic engineering of the iodine content in Arabidopsis. 166
Identification of Two Different Phenotypes of Patients with Amiodarone-Induced Thyrotoxicosis and Positive Thyrotropin Receptor Antibody Tests 165
The Role of Nuclear Medicine in the Clinical Management of Benign Thyroid Disorders, Part 2: Nodular Goiter, Hypothyroidism, and Subacute Thyroiditis 165
Patient with monoclonal gammopathy, thyrotoxicosis, pretibial myxedema and thyroid-associated ophthalmopathy; demonstration of direct binding of autoantibodies to the thyrotropin receptor 163
Thyrotropin receptor polymorphisms and thyroid diseases 163
Functional characteristics of a variant thyrotropin receptor 162
Activating mutations of the TSH receptor gene cause thyroid diseases 161
The effect of voluntary iodine prophylaxis in a small rural community: the Pescopagano survey 15 years later. 161
Influence of iodization programmes on the epidemiology of nodular goitre 160
Epidemiology of congenital hypothyroidism: What can be deduced from the Italian registry of infants with congenital hypothyroidism 160
Functional studies of new thyrotropin receptor (TSHr) mutations identified in patients affected by hypothyroidism or isolated hyperthyrotropinaemia 159
HYPERTHYROIDISM AND PREGNANCY. AN ITALIAN THYROID ASSOCIATION (AIT) AND ITALIAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS (AME) JOINT STATEMENT FOR CLINICAL PRACTICE 159
Oncogenic mutations in thyroid adenoma: methodological criteria 158
Genetics and phenomics of hypothyroidism and thyroid dys- and agenesis due to PAX8 and TTF1 mutations 158
3-Iodothyronamine metabolism and functional effects in FRTL5 thyroid cells. 158
Non-autoimmune subclinical hypothyroidism due to a mutation in TSH receptor: report on two brothers. 157
Presence of a putative steroidal allosteric site on glycoprotein hormone receptors 157
Endothelin-1 up-regulates p115RhoGEF in embryonic rat cardiomyocytes during the hypertrophic response 157
Induction of thyrotropin receptor (TSH-R) autoantibodies and thyroiditis in mice immunised with the recombinant TSH-R 156
Thyroid autoimmunity and female gender 155
Thyrotropin-stimulating hormone receptor gene analysis in pediatric patients with non-autoimmune subclinical hypothyroidism 154
Tissue Distribution and Cardiac Metabolism of 3-Iodothyronamine 154
Recombinant thyrotropin receptor and the induction of autoimmune thyroid 153
Measurement of cAMP accumulation in Chinese hamster ovary cells transfected with the recombinant human TSH receptor (CHO-R): a new bioassay for human thyrotropin 153
The iodine nutritional status in the Italian population: Data from the Italian National Observatory for Monitoring Iodine Prophylaxis (OSNAMI) (period 2015-2019) 153
Thyroid autoimmunity and neuropsychological development 152
Gain of function TSH receptor mutations and iodine deficiency: implications in iodine prophylaxis 151
Expression of IP-10/CXCL10 and MIG/CXCL9 in the thyroid and increased levels of IP-10/CXCL10 in the serum of patients with recent-onset Graves' disease. 151
Papillary thyroid cancer in a patient with congenital goitrous hypothyroidism due to a novel deletion in NIS gene 151
Real-time PCR provides evidence for thyrotropin receptor mRNA expression in orbital as well as in extraorbital tissues 150
Detection of thyroid-stimulating antibody using Chinese hamster ovary cells transfected with cloned human thyrotropin receptor. 149
Detection of 3-Iodothyronamine in human patients: a preliminary study 149
Rare diseases in clinical endocrinology: A taxonomic classification system 149
Radioiodine 131I treatment for large nodular goiter: recombinant human thyrotropin allows the reduction of radioiodine 131I activity to be administered in patients with low uptake 148
Activating PTPN11 mutations play a minor role in pediatric and adult solid tumors 148
Tonacchera M, Banco ME, Montanelli L, Di Cosmo C, Agretti P, De Marco G, Ferrarini E, Ordookhani A, Perri A, Chiovato L, Santini F, Vitti P, Pinchera A. Genetic analysis of the PAX8 gene in children with congenital hypothyroidism and dysgenetic or eutopic thyroid glands: identification of a novel sequence variant 147
Two Italian kindreds with familial hypocalciuric hypercalcaemia caused by loss-of-function mutations in the calcium-sensing receptor (CaR) gene: functional characterization of a novel CaR missense mutation 147
Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia 146
A new case of Marine-Lenhart syndrome with a papillary thyroid carcinoma 146
Identification of TSH receptor mutations in three families with resistance to TSH 145
Expression of cAMP response element-binding protein and sodium iodide symporter in benign non-functioning and malignant thyroid tumours 145
The different requirement of L-T4therapy in congenital athyreosis compared with adult-acquired hypothyroidism suggests a persisting thyroid hormone resistance at the hypothalamic-pituitary level 145
The cAMP in thyroid: from the TSH receptor to mitogenesis and tumorigenesis 144
The thyroid disruptor 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane appears to be an uncompetitive inverse agonist for the thyrotropin receptor 144
Congenital hypothyroidism with impaired thyroid response to thyrotropin (TSH) and absent circulating thyroglobulin: evidence for a new inactivating mutation of the TSH receptor gene. 143
Thyroid autoimmunity may represent a predisposition for the development of fibromyalgia? 142
Expression of cAMP-responsive element binding protein and inducible cAMP early repressor in hyperfunctioning thyroid adenomas. 142
Epidemiology of congenital hypothyroidism: what can be deduced from the Italian registry of infants with congenital hypothyroidism. 141
Totale 17.208
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Categoria #
all - tutte 76.759
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 76.759
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021313 0 0 0 0 0 0 0 0 0 0 97 216
2021/20222.053 26 79 24 111 450 304 96 77 151 93 83 559
2022/20232.462 296 253 154 251 311 338 17 197 461 6 153 25
2023/20241.605 234 174 195 71 224 323 37 24 43 37 59 184
2024/20256.175 21 221 79 383 550 527 528 329 593 809 638 1.497
2025/20265.903 445 849 729 478 634 554 1.107 279 299 455 74 0
Totale 29.459