CINECA IRIS Institutional Research Information System

TONACCHERA, MASSIMO
 Distribuzione geografica
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Continente #
NA - Nord America 17.360
AS - Asia 7.258
EU - Europa 4.722
SA - Sud America 1.014
AF - Africa 326
Continente sconosciuto - Info sul continente non disponibili 319
OC - Oceania 23
Totale 31.022
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Nazione #
US - Stati Uniti d'America 16.867
SG - Singapore 2.175
CN - Cina 2.073
IT - Italia 1.171
HK - Hong Kong 1.118
BR - Brasile 829
SE - Svezia 735
VN - Vietnam 689
DE - Germania 579
BG - Bulgaria 500
CA - Canada 381
TR - Turchia 337
GB - Regno Unito 318
FR - Francia 268
FI - Finlandia 237
UA - Ucraina 233
RU - Federazione Russa 219
KR - Corea 164
IN - India 147
CI - Costa d'Avorio 144
AT - Austria 127
BD - Bangladesh 90
CH - Svizzera 85
JP - Giappone 83
AR - Argentina 60
PK - Pakistan 60
IQ - Iraq 56
NL - Olanda 46
IE - Irlanda 43
MX - Messico 43
SN - Senegal 41
ID - Indonesia 39
SA - Arabia Saudita 37
ZA - Sudafrica 34
EC - Ecuador 33
PL - Polonia 31
ES - Italia 30
BE - Belgio 29
MY - Malesia 26
VE - Venezuela 22
UZ - Uzbekistan 21
CO - Colombia 18
NG - Nigeria 17
AU - Australia 16
KE - Kenya 16
PY - Paraguay 16
GR - Grecia 13
OM - Oman 13
PH - Filippine 13
TT - Trinidad e Tobago 13
JO - Giordania 12
MA - Marocco 12
CZ - Repubblica Ceca 11
JM - Giamaica 11
NP - Nepal 11
PE - Perù 11
UY - Uruguay 11
CL - Cile 10
AE - Emirati Arabi Uniti 9
BJ - Benin 9
EG - Egitto 9
KZ - Kazakistan 9
TN - Tunisia 9
LB - Libano 8
LT - Lituania 8
AL - Albania 7
CR - Costa Rica 7
ET - Etiopia 7
IL - Israele 7
NZ - Nuova Zelanda 7
DZ - Algeria 6
SY - Repubblica araba siriana 6
AZ - Azerbaigian 5
BB - Barbados 5
BH - Bahrain 5
IR - Iran 5
NI - Nicaragua 5
PS - Palestinian Territory 5
QA - Qatar 5
RO - Romania 5
DO - Repubblica Dominicana 4
GE - Georgia 4
HN - Honduras 4
AM - Armenia 3
CY - Cipro 3
DK - Danimarca 3
EU - Europa 3
GT - Guatemala 3
KG - Kirghizistan 3
LY - Libia 3
MM - Myanmar 3
NO - Norvegia 3
PT - Portogallo 3
RS - Serbia 3
SC - Seychelles 3
TH - Thailandia 3
TW - Taiwan 3
VC - Saint Vincent e Grenadine 3
BF - Burkina Faso 2
BM - Bermuda 2
Totale 30.653
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Città #
Woodbridge 1.828
Ashburn 1.777
Fairfield 1.387
Singapore 1.252
Ann Arbor 1.208
Houston 1.146
Hong Kong 1.104
Chandler 922
Santa Clara 705
San Jose 673
Dallas 647
Seattle 592
Wilmington 508
Sofia 496
Shanghai 444
Cambridge 431
Beijing 394
New York 349
Ottawa 295
Milan 287
Jacksonville 282
Council Bluffs 279
Boardman 232
Los Angeles 219
Hefei 213
Princeton 203
Izmir 201
Lawrence 192
Medford 175
Ho Chi Minh City 173
Seoul 163
Lauterbourg 158
Nanjing 154
Abidjan 144
Des Moines 125
Hanoi 113
Serra 113
Munich 110
Vienna 106
Florence 100
Buffalo 94
Istanbul 91
Menlo Park 89
São Paulo 86
Bern 84
Redondo Beach 73
Tokyo 69
Boulder 67
Dong Ket 67
Nanchang 65
Jüchen 57
Columbus 56
Frankfurt am Main 55
San Diego 53
Dearborn 49
Falls Church 48
The Dalles 48
Kunming 44
Lahore 44
Dakar 41
Helsinki 41
Cascina 40
Pisa 40
Detroit 36
Rome 36
London 34
Marseille 34
Hebei 33
Shenyang 33
Atlanta 32
Düsseldorf 32
Ogden 30
Redwood City 30
Chicago 29
Orem 29
Fuzhou 28
Toronto 28
Rio de Janeiro 27
Turku 27
Changsha 26
Phoenix 26
Brussels 25
Guangzhou 25
Lancaster 24
Jinan 23
Washington 23
Amsterdam 22
Tianjin 22
Brasília 21
Bremen 21
Dhaka 21
Haiphong 21
Nuremberg 21
Baghdad 20
Hangzhou 20
San Francisco 20
Da Nang 19
Jiaxing 19
Riyadh 19
Ningbo 18
Totale 22.255
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Nome #
The role of nuclear medicine in the clinical management of benign thyroid disorders. Part 1. Hyperthyroidism 343
Identification of a novel pax8 gene sequence variant in four members of the same family: from congenital hypothyroidism with thyroid hypoplasia to mild subclinical hypothyroidism. 265
Inositols and female reproduction disorders: a consensus statement from the working group of the Club of the Italian Society of Endocrinology (SIE)—Women’s Endocrinology 262
Presence in the pre-surgical fine-needle aspiration of potential thyroid biomarkers previously identified in the post-surgical one. 249
PFOA, PFHxA and C6O4 differently modulate the expression of CXCL8 in normal thyroid cells and in thyroid cancer cell lines 241
Proteomic analysis of fine-needle aspiration in differential diagnosis of thyroid nodules. 235
In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity 217
Iodine contributes to thyroid autoimmunity in humans by unmasking a cryptic epitope on thyroglobulin. 217
uptake of amiodarone by thyroidal and non-thyroidal cell lines 216
Somatic and germline mutations of the TSH receptor gene in thyroid diseases 215
Absence of interference of serum IgGs from patients with breast cancer and thyroid autoimmunity on the function of human iodide symporter gene stably transfected in CHO cells 214
A Combined Therapy with Myo-Inositol and D-Chiro-Inositol Improves Endocrine Parameters and Insulin Resistance in PCOS Young Overweight Women 212
Uptake of amiodarone by thyroidal and non-thyroidal cell lines 210
STUDY OF POTENTIAL INHIBITORS OF THYROID IODIDE UPTAKE BY USING CHO CELLS STABLY EXPRESSING THE HUMAN SODIUM/IODIDE SYMPORTER (hNIS) PROTEIN 206
Effects of a thyroid-stimulating human monoclonal autoantibody (M22) on functional activity of LH and FSH receptors 203
A large-scale association study to assess the impact of known variants of the human INHA gene on premature ovarian failure 196
Absence of interference of serum IgGs from patients with breast cancer and thyroid autoimmunity on the function of human iodide symporter gene stably transfected in CHO cells 196
Ras homolog enriched in striatum inhibits the functional activity of wild type thyrotropin, follicle-stimulating hormone, luteinizing hormone receptors and activating thyrotropin receptor mutations by altering their expression in COS-7 cells 196
Genetic mutations in the treatment of anaplastic thyroid cancer: a systematic review. 195
Evaluation of l-thyroxine replacement therapy in children with congenital hypothyroidism 194
Electric and magnetic fields do not modify the biochemical properties of FRTL-5 cells 194
The thyroperoxidase doublet is not produced by alternative splicing 192
Expression of IP-10/CXCL10 and MIG/CXCL9 in the thyroid and increased levels of IP-10/CXCL10 in the serum of patients with recent-onset Graves' disease 192
Activating thyrotropin receptor mutations are present in nonadenomatous hyperfunctioning nodules of toxic or autonomous multinodular goiter 190
Agretti P, De Marco G, De Servi M, Marcocci C, Vitti P, Pinchera A, Tonacchera M.: Evidence for protein and mRNA TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy (TAO) after adipocytic differentiation 189
The large majority of 1520 patients with indeterminate thyroid nodule at cytology have a favorable outcome, and a clinical risk score has a high negative predictive value for a more cumbersome cancer disease. 189
Iodine nutrition status, thyroid function in the first trimester of pregnancy and pregnancy progression in women residing in an area of know moderate iodine deficiency 189
Activating thyrotropin receptor mutations in histologically heterogeneous hyperfunctioning nodules of multinodular goiter. 188
TSH receptor antibodies do not alter the function of gonadotropin receptors stably expressed in eukaryotic cells 187
Patients with indeterminate thyroid nodules at cytology and cancer at histology have a more favourable outcome with respect to patients with suspicious or malignant cytology 186
Iodine deficiency from pregnancy to childhood 185
Mapping thyroid peroxidase epitopes using recombinant protein fragments 184
Differential effects of NaCl concentration on the constitutive activity of the thyrotropin and the luteinizing hormone/chorionic gonadotropin receptors 184
Gonadotrophin receptor blocking antibodies measured by the use of cell lines stably expressing human gonadotrophin receptors are not detectable in women with 46,XX premature ovarian failure 184
High risk of congenital hypothyroidism in multiple pregnancies 183
Diagnostic utility of BRAFV600E mutation testing in thyroid nodules in elderly patients. 181
The G protein-coupled receptor family and one of its members, the TSH receptor 181
Screening for drugs potentially interfering with MCT8-mediated T 3 transport in vitro identifies dexamethasone and some commonly used drugs as inhibitors of MCT8 activity 181
Constitutively active receptors as a disease-causing mechanism 180
Blood cell mitochondrial DNA content and premature ovarian aging. 180
Functioning and non functioning thyroid adenomas involve different molecular pathogenetic mechanisms 180
GENETIC MARKERS TO DISCRIMINATE BENIGN AND MALIGNANT THYROID NODULES WITH UNDETERMINED CYTOLOGY IN AN AREA OF BORDERLINE IODINE DEFICIENCY. 179
Assessment of nodular goitre 178
Patients with Indeterminate Thyroid Nodules at Cytology and Cancer at Histology Have a More Favorable Outcome Compared with Patients with Suspicious or Malignant Cytology 178
Markers of cell proliferation, apoptosis, and angiogenesis in thyroid adenomas: a comparative immunohistochemical and genetic investigation of functioning and nonfunctioning nodules 176
Detection of circulating autoantibodies against thyroid hormones in an infant with permanent congenital hypothyroidism and her twin with transient congenital hypothyroidism: possible contribution of thyroid hormone autoantibodies to neonatal and infant hypothyroidism 175
Identification and functional studies of two new dual-oxidase 2 (DUOX2) mutations in a child with congenital hypothyroidism and a eutopic normal-size thyroid gland 175
A Fast Method to Detect Cell Surface Expression of Thyrotropin Receptor (TSHr): The Microchip Flow Cytometry Analysis 174
The way forward in Italy for iodine 174
Genetic interaction analysis of VEGF-A rs3025039 and VEGFR-2 rs2071559 identifies a genetic profile at higher risk to develop nodular goiter 174
Cloning of candidate autoantigen carboxypeptidase H from a human islet library: sequence identity with human brain CPH 173
Metabolic engineering of the iodine content in Arabidopsis. 173
Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid 172
Thyrotropin receptor polymorphisms and thyroid diseases 172
Autoantibodies from patients with autoimmune thyroid disease do not interfere with the activity of the human iodide symporter gene stably transfected in CHO cells. 172
Iodine fortification of vegetables improves human iodine nutrition: In vivo evidence for a new model of iodine prophylaxis 172
The Role of Nuclear Medicine in the Clinical Management of Benign Thyroid Disorders, Part 2: Nodular Goiter, Hypothyroidism, and Subacute Thyroiditis 171
Low prevalence of thyrotropin receptor mutations in a large series of subjects with sporadic and familial nonautoimmune subclinical hypothyroidism 170
Identification of Two Different Phenotypes of Patients with Amiodarone-Induced Thyrotoxicosis and Positive Thyrotropin Receptor Antibody Tests 170
Evidences for an allelic variant of the human LC/CG receptor rather than a gene duplication: functional comparison of wild-type and variant receptors 169
The Italian screening program for primary congenital hypothyroidism: actions to improve screening, diagnosis, follow-up, and surveillance. 169
The effect of voluntary iodine prophylaxis in a small rural community: the Pescopagano survey 15 years later. 168
Genetics and phenomics of hypothyroidism and thyroid dys- and agenesis due to PAX8 and TTF1 mutations 166
Patient with monoclonal gammopathy, thyrotoxicosis, pretibial myxedema and thyroid-associated ophthalmopathy; demonstration of direct binding of autoantibodies to the thyrotropin receptor 165
Functional characteristics of a variant thyrotropin receptor 165
Activating mutations of the TSH receptor gene cause thyroid diseases 165
Functional studies of new thyrotropin receptor (TSHr) mutations identified in patients affected by hypothyroidism or isolated hyperthyrotropinaemia 164
Influence of iodization programmes on the epidemiology of nodular goitre 164
Epidemiology of congenital hypothyroidism: What can be deduced from the Italian registry of infants with congenital hypothyroidism 163
Induction of thyrotropin receptor (TSH-R) autoantibodies and thyroiditis in mice immunised with the recombinant TSH-R 162
Oncogenic mutations in thyroid adenoma: methodological criteria 161
Non-autoimmune subclinical hypothyroidism due to a mutation in TSH receptor: report on two brothers. 161
HYPERTHYROIDISM AND PREGNANCY. AN ITALIAN THYROID ASSOCIATION (AIT) AND ITALIAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS (AME) JOINT STATEMENT FOR CLINICAL PRACTICE 161
3-Iodothyronamine metabolism and functional effects in FRTL5 thyroid cells. 161
Tissue Distribution and Cardiac Metabolism of 3-Iodothyronamine 160
Presence of a putative steroidal allosteric site on glycoprotein hormone receptors 160
Thyroid autoimmunity and female gender 159
Endothelin-1 up-regulates p115RhoGEF in embryonic rat cardiomyocytes during the hypertrophic response 159
The iodine nutritional status in the Italian population: Data from the Italian National Observatory for Monitoring Iodine Prophylaxis (OSNAMI) (period 2015-2019) 159
Measurement of cAMP accumulation in Chinese hamster ovary cells transfected with the recombinant human TSH receptor (CHO-R): a new bioassay for human thyrotropin 158
Recombinant thyrotropin receptor and the induction of autoimmune thyroid 157
Detection of thyroid-stimulating antibody using Chinese hamster ovary cells transfected with cloned human thyrotropin receptor. 157
Gain of function TSH receptor mutations and iodine deficiency: implications in iodine prophylaxis 155
Thyrotropin-stimulating hormone receptor gene analysis in pediatric patients with non-autoimmune subclinical hypothyroidism 155
Real-time PCR provides evidence for thyrotropin receptor mRNA expression in orbital as well as in extraorbital tissues 155
Thyroid autoimmunity and neuropsychological development 154
Papillary thyroid cancer in a patient with congenital goitrous hypothyroidism due to a novel deletion in NIS gene 154
Rare diseases in clinical endocrinology: A taxonomic classification system 154
Expression of IP-10/CXCL10 and MIG/CXCL9 in the thyroid and increased levels of IP-10/CXCL10 in the serum of patients with recent-onset Graves' disease. 153
Detection of 3-Iodothyronamine in human patients: a preliminary study 153
Radioiodine 131I treatment for large nodular goiter: recombinant human thyrotropin allows the reduction of radioiodine 131I activity to be administered in patients with low uptake 152
Expression of cAMP response element-binding protein and sodium iodide symporter in benign non-functioning and malignant thyroid tumours 152
Two Italian kindreds with familial hypocalciuric hypercalcaemia caused by loss-of-function mutations in the calcium-sensing receptor (CaR) gene: functional characterization of a novel CaR missense mutation 150
Activating PTPN11 mutations play a minor role in pediatric and adult solid tumors 150
A new case of Marine-Lenhart syndrome with a papillary thyroid carcinoma 150
Identification of TSH receptor mutations in three families with resistance to TSH 149
The cAMP in thyroid: from the TSH receptor to mitogenesis and tumorigenesis 148
Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia 148
Tonacchera M, Banco ME, Montanelli L, Di Cosmo C, Agretti P, De Marco G, Ferrarini E, Ordookhani A, Perri A, Chiovato L, Santini F, Vitti P, Pinchera A. Genetic analysis of the PAX8 gene in children with congenital hypothyroidism and dysgenetic or eutopic thyroid glands: identification of a novel sequence variant 148
The different requirement of L-T4therapy in congenital athyreosis compared with adult-acquired hypothyroidism suggests a persisting thyroid hormone resistance at the hypothalamic-pituitary level 148
Totale 17.970
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Categoria #
all - tutte 84.331
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 84.331
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20222.027 0 79 24 111 450 304 96 77 151 93 83 559
2022/20232.462 296 253 154 251 311 338 17 197 461 6 153 25
2023/20241.605 234 174 195 71 224 323 37 24 43 37 59 184
2024/20256.175 21 221 79 383 550 527 528 329 593 809 638 1.497
2025/20266.169 445 849 729 478 634 554 1.107 279 299 455 203 137
2026/20271.297 462 835 0 0 0 0 0 0 0 0 0 0
Totale 31.022