CINECA IRIS Institutional Research Information System

TONACCHERA, MASSIMO
 Distribuzione geografica
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Continente #
NA - Nord America 12.759
EU - Europa 3.781
AS - Asia 2.110
AF - Africa 206
SA - Sud America 46
OC - Oceania 14
Continente sconosciuto - Info sul continente non disponibili 4
Totale 18.920
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Nazione #
US - Stati Uniti d'America 12.447
IT - Italia 1.038
CN - Cina 1.029
SE - Svezia 732
BG - Bulgaria 495
SG - Singapore 463
DE - Germania 425
CA - Canada 310
TR - Turchia 297
GB - Regno Unito 227
UA - Ucraina 211
FI - Finlandia 177
VN - Vietnam 171
CI - Costa d'Avorio 142
AT - Austria 106
RU - Federazione Russa 97
CH - Svizzera 84
FR - Francia 57
HK - Hong Kong 47
BR - Brasile 39
SN - Senegal 39
IE - Irlanda 35
IN - India 34
BE - Belgio 25
PK - Pakistan 23
NL - Olanda 17
PL - Polonia 13
GR - Grecia 12
NG - Nigeria 11
AU - Australia 9
BJ - Benin 9
JP - Giappone 9
CZ - Repubblica Ceca 8
MY - Malesia 8
IR - Iran 5
NZ - Nuova Zelanda 5
ES - Italia 4
ID - Indonesia 4
LT - Lituania 4
AR - Argentina 3
EU - Europa 3
MM - Myanmar 3
AZ - Azerbaigian 2
DK - Danimarca 2
DZ - Algeria 2
EG - Egitto 2
IQ - Iraq 2
KR - Corea 2
NO - Norvegia 2
PE - Perù 2
RO - Romania 2
SA - Arabia Saudita 2
A1 - Anonimo 1
AE - Emirati Arabi Uniti 1
AL - Albania 1
BA - Bosnia-Erzegovina 1
BD - Bangladesh 1
BH - Bahrain 1
BY - Bielorussia 1
CL - Cile 1
CO - Colombia 1
HR - Croazia 1
HU - Ungheria 1
IL - Israele 1
KW - Kuwait 1
MD - Moldavia 1
ME - Montenegro 1
MT - Malta 1
MX - Messico 1
NP - Nepal 1
OM - Oman 1
PR - Porto Rico 1
QA - Qatar 1
TW - Taiwan 1
ZA - Sudafrica 1
Totale 18.920
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Città #
Woodbridge 1.828
Fairfield 1.390
Ann Arbor 1.208
Houston 1.139
Chandler 931
Santa Clara 692
Ashburn 672
Seattle 587
Wilmington 507
Sofia 494
Cambridge 431
New York 307
Beijing 299
Ottawa 295
Singapore 286
Milan 283
Jacksonville 278
Boardman 226
Princeton 205
Izmir 200
Lawrence 194
Medford 177
Nanjing 154
Abidjan 142
Des Moines 123
Serra 113
Florence 99
Vienna 97
Menlo Park 89
Bern 84
Istanbul 81
Boulder 67
Dong Ket 67
Nanchang 65
Jüchen 57
San Diego 54
Dearborn 48
Falls Church 48
Hong Kong 44
Kunming 44
Dakar 39
Shanghai 37
Pisa 35
Detroit 33
Hebei 33
Los Angeles 33
Marseille 33
Frankfurt am Main 32
Ogden 32
Shenyang 32
Fuzhou 30
Redwood City 30
Rome 28
London 24
Brussels 23
Changsha 23
Düsseldorf 23
Lahore 23
Jinan 22
Lancaster 22
Tianjin 22
Bremen 21
Munich 21
Washington 20
Guangzhou 19
Hangzhou 19
Jiaxing 19
Ningbo 18
Hefei 17
Dallas 16
Norwalk 15
Chicago 14
Nürnberg 14
Pune 14
Orange 13
Quanzhou 13
Auburn Hills 11
Kocaeli 11
Lagos 11
Phoenix 10
Zhengzhou 10
Cotonou 9
Helsinki 9
Lanzhou 9
Chengdu 8
Sacile 8
Brno 7
Indiana 7
Wuhan 7
Vicopisano 6
Cascina 5
Changchun 5
Fauglia 5
Kuala Lumpur 5
L'aquila 5
San Francisco 5
Taizhou 5
Xiamen 5
Auckland 4
Genoa 4
Totale 15.138
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Nome #
The role of nuclear medicine in the clinical management of benign thyroid disorders. Part 1. Hyperthyroidism 220
Identification of a novel pax8 gene sequence variant in four members of the same family: from congenital hypothyroidism with thyroid hypoplasia to mild subclinical hypothyroidism. 179
uptake of amiodarone by thyroidal and non-thyroidal cell lines 170
Presence in the pre-surgical fine-needle aspiration of potential thyroid biomarkers previously identified in the post-surgical one. 169
A Combined Therapy with Myo-Inositol and D-Chiro-Inositol Improves Endocrine Parameters and Insulin Resistance in PCOS Young Overweight Women 157
In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity 155
Proteomic analysis of fine-needle aspiration in differential diagnosis of thyroid nodules. 155
Somatic and germline mutations of the TSH receptor gene in thyroid diseases 151
Absence of interference of serum IgGs from patients with breast cancer and thyroid autoimmunity on the function of human iodide symporter gene stably transfected in CHO cells 150
Blood cell mitochondrial DNA content and premature ovarian aging. 149
A large-scale association study to assess the impact of known variants of the human INHA gene on premature ovarian failure 148
Effects of a thyroid-stimulating human monoclonal autoantibody (M22) on functional activity of LH and FSH receptors 146
STUDY OF POTENTIAL INHIBITORS OF THYROID IODIDE UPTAKE BY USING CHO CELLS STABLY EXPRESSING THE HUMAN SODIUM/IODIDE SYMPORTER (hNIS) PROTEIN 143
Electric and magnetic fields do not modify the biochemical properties of FRTL-5 cells 142
Agretti P, De Marco G, De Servi M, Marcocci C, Vitti P, Pinchera A, Tonacchera M.: Evidence for protein and mRNA TSHr expression in fibroblasts from patients with thyroid-associated ophthalmopathy (TAO) after adipocytic differentiation 141
Absence of interference of serum IgGs from patients with breast cancer and thyroid autoimmunity on the function of human iodide symporter gene stably transfected in CHO cells 140
Autoantibodies from patients with autoimmune thyroid disease do not interfere with the activity of the human iodide symporter gene stably transfected in CHO cells. 138
Expression of IP-10/CXCL10 and MIG/CXCL9 in the thyroid and increased levels of IP-10/CXCL10 in the serum of patients with recent-onset Graves' disease 137
Activating thyrotropin receptor mutations are present in nonadenomatous hyperfunctioning nodules of toxic or autonomous multinodular goiter 137
Iodine deficiency from pregnancy to childhood 137
Assessment of nodular goitre 136
Iodine nutrition status, thyroid function in the first trimester of pregnancy and pregnancy progression in women residing in an area of know moderate iodine deficiency 135
Iodine contributes to thyroid autoimmunity in humans by unmasking a cryptic epitope on thyroglobulin. 135
The thyroperoxidase doublet is not produced by alternative splicing 133
Activating thyrotropin receptor mutations in histologically heterogeneous hyperfunctioning nodules of multinodular goiter. 132
Detection of circulating autoantibodies against thyroid hormones in an infant with permanent congenital hypothyroidism and her twin with transient congenital hypothyroidism: possible contribution of thyroid hormone autoantibodies to neonatal and infant hypothyroidism 129
High risk of congenital hypothyroidism in multiple pregnancies 129
Identification and functional studies of two new dual-oxidase 2 (DUOX2) mutations in a child with congenital hypothyroidism and a eutopic normal-size thyroid gland 128
Thyrotropin receptor polymorphisms and thyroid diseases 126
Constitutively active receptors as a disease-causing mechanism 125
Differential effects of NaCl concentration on the constitutive activity of the thyrotropin and the luteinizing hormone/chorionic gonadotropin receptors 125
Metabolic engineering of the iodine content in Arabidopsis. 124
Functioning and non functioning thyroid adenomas involve different molecular pathogenetic mechanisms 124
The large majority of 1520 patients with indeterminate thyroid nodule at cytology have a favorable outcome, and a clinical risk score has a high negative predictive value for a more cumbersome cancer disease. 124
HYPERTHYROIDISM AND PREGNANCY. AN ITALIAN THYROID ASSOCIATION (AIT) AND ITALIAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS (AME) JOINT STATEMENT FOR CLINICAL PRACTICE 123
Cloning of candidate autoantigen carboxypeptidase H from a human islet library: sequence identity with human brain CPH 122
Functional characteristics of a variant thyrotropin receptor 121
Low prevalence of thyrotropin receptor mutations in a large series of subjects with sporadic and familial nonautoimmune subclinical hypothyroidism 121
Genetic mutations in the treatment of anaplastic thyroid cancer: a systematic review. 120
Markers of cell proliferation, apoptosis, and angiogenesis in thyroid adenomas: a comparative immunohistochemical and genetic investigation of functioning and nonfunctioning nodules 120
Mapping thyroid peroxidase epitopes using recombinant protein fragments 119
Gonadotrophin receptor blocking antibodies measured by the use of cell lines stably expressing human gonadotrophin receptors are not detectable in women with 46,XX premature ovarian failure 119
TSH receptor antibodies do not alter the function of gonadotropin receptors stably expressed in eukaryotic cells 119
Non-autoimmune subclinical hypothyroidism due to a mutation in TSH receptor: report on two brothers. 117
Detection of 3-Iodothyronamine in human patients: a preliminary study 117
A Fast Method to Detect Cell Surface Expression of Thyrotropin Receptor (TSHr): The Microchip Flow Cytometry Analysis 117
Patients with indeterminate thyroid nodules at cytology and cancer at histology have a more favourable outcome with respect to patients with suspicious or malignant cytology 117
Patient with monoclonal gammopathy, thyrotoxicosis, pretibial myxedema and thyroid-associated ophthalmopathy; demonstration of direct binding of autoantibodies to the thyrotropin receptor 116
Evaluation of l-thyroxine replacement therapy in children with congenital hypothyroidism 116
Thyroid autoimmunity and female gender 115
Evidences for an allelic variant of the human LC/CG receptor rather than a gene duplication: functional comparison of wild-type and variant receptors 115
Expression of IP-10/CXCL10 and MIG/CXCL9 in the thyroid and increased levels of IP-10/CXCL10 in the serum of patients with recent-onset Graves' disease. 114
Activating mutations of the TSH receptor gene cause thyroid diseases 113
Thyrotropin-stimulating hormone receptor gene analysis in pediatric patients with non-autoimmune subclinical hypothyroidism 112
Tissue Distribution and Cardiac Metabolism of 3-Iodothyronamine 112
Two Italian kindreds with familial hypocalciuric hypercalcaemia caused by loss-of-function mutations in the calcium-sensing receptor (CaR) gene: functional characterization of a novel CaR missense mutation 111
Iodine fortification of vegetables improves human iodine nutrition: In vivo evidence for a new model of iodine prophylaxis 111
Influence of iodization programmes on the epidemiology of nodular goitre 110
Genetics and phenomics of hypothyroidism and thyroid dys- and agenesis due to PAX8 and TTF1 mutations 109
Real-time PCR provides evidence for thyrotropin receptor mRNA expression in orbital as well as in extraorbital tissues 109
Diagnostic utility of BRAFV600E mutation testing in thyroid nodules in elderly patients. 107
The G protein-coupled receptor family and one of its members, the TSH receptor 107
null 107
Functional studies of new thyrotropin receptor (TSHr) mutations identified in patients affected by hypothyroidism or isolated hyperthyrotropinaemia 106
Thyroid autoimmunity may represent a predisposition for the development of fibromyalgia? 106
3-Iodothyronamine metabolism and functional effects in FRTL5 thyroid cells. 106
Measurement of cAMP accumulation in Chinese hamster ovary cells transfected with the recombinant human TSH receptor (CHO-R): a new bioassay for human thyrotropin 106
Expression of cAMP response element-binding protein and sodium iodide symporter in benign non-functioning and malignant thyroid tumours 106
Presence of a putative steroidal allosteric site on glycoprotein hormone receptors 105
GENETIC MARKERS TO DISCRIMINATE BENIGN AND MALIGNANT THYROID NODULES WITH UNDETERMINED CYTOLOGY IN AN AREA OF BORDERLINE IODINE DEFICIENCY. 105
Endothelin-1 up-regulates p115RhoGEF in embryonic rat cardiomyocytes during the hypertrophic response 105
Oncogenic mutations in thyroid adenoma: methodological criteria 104
Tonacchera M, Banco ME, Montanelli L, Di Cosmo C, Agretti P, De Marco G, Ferrarini E, Ordookhani A, Perri A, Chiovato L, Santini F, Vitti P, Pinchera A. Genetic analysis of the PAX8 gene in children with congenital hypothyroidism and dysgenetic or eutopic thyroid glands: identification of a novel sequence variant 104
Congenital hypothyroidism with impaired thyroid response to thyrotropin (TSH) and absent circulating thyroglobulin: evidence for a new inactivating mutation of the TSH receptor gene. 103
Epidemiology of congenital hypothyroidism: what can be deduced from the Italian registry of infants with congenital hypothyroidism. 103
Functional characteristics of three new germline mutations of the thyrotropin receptor gene causing autosomal dominant toxic thyroid hyperplasia 102
The sodium-iodide symporter protein is always present at a low expression and confined to the cell membrane in nonfunctioning nonadenomatous nodules of toxic nodular goitre 102
null 102
Genetic analysis of the TSH receptor gene in differentiated human thyroid carcinomas 101
Incidence of congenital hypothyroidism in the Autonomous Province of Bolzano: Benefit of increased iodine intake 101
The Italian National Register of infants with congenital hypothyroidism: Twenty years of surveillance and study of congenital hypothyroidism 101
The thyroid disruptor 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane appears to be an uncompetitive inverse agonist for the thyrotropin receptor 100
Congenital hypothyroidism due to a new deletion in the sodium/iodide symporter protein 100
Detection of thyroid-stimulating antibody using Chinese hamster ovary cells transfected with cloned human thyrotropin receptor. 99
Relative potencies and additivity of perchlorate, thiocyanate, nitrate, and iodide on the inhibition of radioactive iodide uptake by the human sodium iodide symporter 99
Identification of TSH receptor mutations in three families with resistance to TSH 99
Identification and functional characterization of two new somatic mutations causing constitutive activation of the thyrotropin receptor in hyperfunctioning autonomous adenomas of the thyroid 98
Expression of cAMP-responsive element binding protein and inducible cAMP early repressor in hyperfunctioning thyroid adenomas. 98
Evidence for the secretion of thyrotropin with enhanced bioactivity in syndromes of thyroid hormone resistance. 98
Activating PTPN11 mutations play a minor role in pediatric and adult solid tumors 98
null 98
Induction of thyrotropin receptor (TSH-R) autoantibodies and thyroiditis in mice immunised with the recombinant TSH-R 97
Gain of function TSH receptor mutations and iodine deficiency: implications in iodine prophylaxis 97
Thyroid hormone action in the adult brain: gene expression profiling of the effects of single and multiple doses of triiodo-L-thyronine in the rat striatum 97
Thyroid resistance to TSH complicated by autoimmune thyroiditis. 97
TSH receptor and Gs(alpha) genetic analysis in children with Down's syndrome and subclinical hypothyroidism 97
Somatic mutations causing constitutive activity of the thyrotropin receptor are the major cause of hyperfunctioning thyroid adenomas: identification of additional mutations activating both the cyclic adenosine 3',5'-monophosphate and inositol phosphate-Ca2+ cascades 96
Autoimmune hypothyroidism and hyperthyroidism in patients with Turner's syndrome 96
Papillary thyroid cancer in a patient with congenital goitrous hypothyroidism due to a novel deletion in NIS gene 96
null 95
Totale 11.928
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Categoria #
all - tutte 50.590
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 50.590
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.030 0 0 0 0 0 382 425 312 377 207 266 61
2020/20211.528 151 79 105 62 142 62 104 136 142 232 97 216
2021/20222.070 26 79 24 111 450 304 102 80 151 94 85 564
2022/20232.505 301 256 158 252 314 342 17 198 471 9 155 32
2023/20241.664 234 178 201 82 231 331 42 24 45 40 66 190
2024/20251.683 29 228 83 394 569 380 0 0 0 0 0 0
Totale 19.183