CINECA IRIS Institutional Research Information System

BROGI, SIMONE
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 7.851
EU - Europa 1.694
AS - Asia 1.135
AF - Africa 44
SA - Sud America 13
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 6
Totale 10.750
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 5.516
CA - Canada 2.333
IT - Italia 620
CN - Cina 596
SE - Svezia 477
BG - Bulgaria 285
SG - Singapore 276
VN - Vietnam 95
TR - Turchia 84
DE - Germania 66
GB - Regno Unito 64
FI - Finlandia 39
HK - Hong Kong 36
BE - Belgio 30
CI - Costa d'Avorio 30
IN - India 20
RU - Federazione Russa 19
FR - Francia 18
CH - Svizzera 15
GR - Grecia 13
PL - Polonia 11
BR - Brasile 10
AU - Australia 6
EU - Europa 6
KR - Corea 6
UA - Ucraina 6
BD - Bangladesh 5
ES - Italia 5
IE - Irlanda 5
AT - Austria 4
CZ - Repubblica Ceca 4
NL - Olanda 4
PK - Pakistan 4
SN - Senegal 4
AR - Argentina 3
IR - Iran 3
LT - Lituania 3
MU - Mauritius 3
SA - Arabia Saudita 3
ZA - Sudafrica 3
JP - Giappone 2
MX - Messico 2
NG - Nigeria 2
PT - Portogallo 2
RO - Romania 2
TW - Taiwan 2
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
EG - Egitto 1
IL - Israele 1
MA - Marocco 1
MY - Malesia 1
NZ - Nuova Zelanda 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 10.750
Salva come PNG Salva come JPEG
Città #
Montreal 2.309
Fairfield 915
Santa Clara 512
Woodbridge 452
Ashburn 433
Seattle 402
Cambridge 334
Wilmington 306
Houston 300
Shanghai 288
Sofia 284
Milan 276
Boulder 265
Chandler 225
New York 216
Boardman 163
Singapore 121
Princeton 118
Lawrence 113
Ann Arbor 106
Medford 76
Istanbul 74
Des Moines 64
Dong Ket 51
San Diego 40
Rome 37
Beijing 35
London 35
Chicago 34
Grafing 32
Abidjan 30
Hong Kong 30
Quanzhou 30
Lappeenranta 29
Serra 28
Brussels 27
Nanjing 26
Siena 26
Los Angeles 21
Fuzhou 19
Frankfurt am Main 16
Nanchang 16
Ogden 16
Hebei 14
Florence 13
Xiamen 13
Falls Church 12
Marseille 11
Norwalk 11
Livorno 10
San Jose 10
Toronto 10
Dearborn 9
Helsinki 9
Warsaw 9
Changsha 8
Shenyang 8
Tianjin 7
Bern 6
Dallas 6
Hyderabad 6
Lucca 6
Montréal 6
Mumbai 6
West Jordan 6
Dublin 5
Guangzhou 5
Hangzhou 5
Ottawa 5
Pisa 5
São Paulo 5
Dakar 4
Izmir 4
Kunming 4
Naples 4
Redwood City 4
Brno 3
Castelliri 3
Council Bluffs 3
Dhaka 3
Gujrat 3
Madrid 3
Melbourne 3
Napoli 3
North York 3
Ospitaletto 3
Pieve 3
Porto Alegre 3
San Piero a Sieve 3
Southwark 3
Tekirdağ 3
Uppsala 3
Vienna 3
Washington 3
Acton 2
Azeitao 2
Ballynahinch 2
Bologna 2
Borås 2
Camaiore 2
Totale 9.242
Salva come PNG Salva come JPEG
Nome #
0365: Non-peptidic prokineticin receptor 1 agonist as a novel cardioprotective therapeutic 2.620
The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1 165
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements and Structural and Biological Investigation 140
NOVEL ANALGESIC/ANTI-INFLAMMATORY AGENTS: 1,5-DIARYLPYRROLE NITROOXYALKYL ETHERS AND RELATED COMPOUNDS AS CYCLOOXYGENASE-2 INHIBITING NITRIC OXIDE DONORS 132
Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages 123
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents 116
Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare Diseases 109
Dealing with schistosomiasis: Current drug discovery strategies 102
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain 100
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 100
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain 99
Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA B receptor 97
Mimicking the intramolecular hydrogen bond: Synthesis, biological evaluation, andmolecular modeling of benzoxazines and quinazolines as potential antimalarial agents 95
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues 93
3D-QSAR using pharmacophore-based alignment and virtual screening for discovery of novel MCF-7 cell line inhibitors 93
Breakthroughs in Computational Approaches for Drug Discovery 92
Dietary polyphenols rutin, taxifolin and quercetin related compounds target: Leishmania amazonensis arginase 91
Rational design of the first difluorostatone-based PfSUB1 inhibitors 89
Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II) 88
Discovery and Cardioprotective Effects of the First Non-Peptide Agonists of the G-Protein-Coupled Prokineticin Receptor-1 88
Cinnamic acids derived compounds with antileishmanial activity target Leishmania amazonensis arginase 88
Synthesis and Biological Evaluation of Novel Neuroprotective Pyridazine Derivatives as Excitatory Amino Acid Transporter 2 (EAAT2) Activators 86
Amyloid β fibril disruption by oleuropein aglycone: long-time molecular dynamics simulation to gain insight into the mechanism of action of this polyphenol from extra virgin olive oil 86
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: Further structure-activity relationships, in vivo studies, and preliminary toxicity profiling 84
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity 84
Computational Approaches for Drug Discovery 83
Activation of the Wnt Pathway by Small Peptides: Rational Design, Synthesis and Biological Evaluation 83
A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision 82
Exploring clotrimazole-based pharmacophore: 3D-QSAR studies and synthesis of novel antiplasmodial agents 82
Phenylpyrrole-based HDAC inhibitors: Synthesis, molecular modeling and biological studies 82
Pharmacophore modeling for qualitative prediction of antiestrogenic activity 81
iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome 81
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies 80
Plasmodium falciparum subtilisin-like protease 1: Discovery of potent difluorostatone-based inhibitors 80
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems 80
Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2 79
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents 78
Identification of novel fluorescent probes preventing PrPScreplication in prion diseases 78
Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease 77
Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: Definition of the structural determinants for enzyme inhibition 77
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1 77
Telomerase-based cancer therapeutics: a review on their clinical trials 77
Polypharmacology of dopamine receptor ligands 76
Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation 76
A stereoselective approach to peptidomimetic BACE1 inhibitors 76
Computational tool for fast in silico evaluation of hERG K+ channel affinity 75
From (+)-epigallocatechin gallate to a simplified synthetic analogue as a cytoadherence inhibitor for P. falciparum 75
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents 75
Synthesis and antiplasmodial activity of bicyclic dioxanes as simplified dihydroplakortin analogues 75
Discovery and cardioprotective effects of the first non-peptide agonists of the G protein-coupled prokineticin receptor-1 75
Multifunctional cholinesterase and amyloid beta fibrillization modulators. Synthesis and biological investigation 74
Synthetic spirocyclic endoperoxides: New antimalarial scaffolds 74
Synthesis and structure-activity relationship studies in serotonin 5-HT1A receptor agonists based on fused pyrrolidone scaffolds 74
Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: Potent and selective CB2 cannabinoid receptor inverse agonists 74
Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches to Treat Central Nervous System Disorders 74
Development of HuperTacrines as non-toxic, cholinesterase inhibitors for the potential treatment of Alzheimer’s disease 74
Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal Agents 74
Cinnamides Target Leishmania amazonensis Arginase Selectively 74
HCV-targeted antivirals: Current status and future challenges 73
Synthesis, Molecular Modelling and Biological Studies of 3-hydroxy-pyrane-4-one and 3-hydroxy-pyridine-4-one Derivatives as HIV-1 Integrase Inhibitors 72
Discovery of iminobenzimidazole derivatives as novel cytotoxic agents 72
Development of novel cyclic peptides as pro-apoptotic agents 72
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 72
Anti-inflammatory and antiviral roles of hydrogen sulfide: Rationale for considering H2S donors in COVID-19 therapy 72
Role of hydrogen sulfide in endothelial dysfunction: Pathophysiology and therapeutic approaches 72
Development of a practical and scalable route for the preparation of the deacetoxytubuvaline (dTuv) fragment of pretubulysin and analogs 71
Abstract 411: Discovery and Cardioprotective Effects of the First Non-peptide Agonists of Prokineticin Receptor-1 71
Targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors for developing effective antipsychotics: Synthesis, biological characterization, and behavioral studies 70
A repurposing approach for uncovering the anti-tubercular activity of FDA-approved drugs with Potential Multi-Targeting Profiles 70
Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors 69
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX 69
Synthetic studies toward bicyclic endoperoxides presenting polar side chains 69
Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold 69
Discovery of GPCR ligands for probing signal transduction pathways 69
First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents 68
In silico study of subtilisin-like protease 1 (SUB1) from different Plasmodium species in complex with peptidyl-difluorostatones and characterization of potent pan-SUB1 inhibitors 68
Organic Isothiocyanates as Hydrogen Sulfide Donors 68
MicroRNA-Based Multitarget Approach for Alzheimer's Disease: Discovery of the First-In-Class Dual Inhibitor of Acetylcholinesterase and MicroRNA-15b Biogenesis 67
Development of In Vitro Corneal Models: Opportunity for Pharmacological Testing 64
An integrated in silico screening strategy for identifying promising disruptors of p53-MDM2 interaction 63
Design, synthesis and biological evaluation of 7-substituted 4-phenyl-6H-imidazo[1,5-a]thieno[3,2-f] [1,4]diazepines as safe anxiolytic agents 61
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 58
Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents 57
Identification of novel SIRT1 activators endowed with cardioprotective profile 57
The structural evolution of β-secretase inhibitors: A focus on the development of small-molecule inhibitors 55
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases 54
Verbascoside Inhibits Promastigote Growth and Arginase Activity of Leishmania amazonensis 54
Tetrahydrofuran acetogenins from Laurencia glandulifera 49
Disease-modifying anti-Alzheimer's drugs: Inhibitors of human cholinesterases interfering with β-amyloid aggregation 49
Computer-Driven Development of an in Silico Tool for Finding Selective Histone Deacetylase 1 Inhibitors 49
Artificial Intelligence in Translational Medicine 48
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 46
IN SILICO METHODS FOR DRUG DESIGN AND DISCOVERY 45
Role of hydrogen sulfide in cardiovascular ageing 43
Identification of Novel 3-Hydroxy-pyran-4-One Derivatives as Potent HIV-1 Integrase Inhibitors Using in silico Structure-Based Combinatorial Library Design Approach 43
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation 43
Computer-based approaches for determining the pharmacological profile of 5-(3-nitro-arylidene)-thiazolidine-2,4-dione 43
Off-target ACE2 ligands: possible therapeutic option for CoVid-19? 39
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents 39
Myxobacterial depsipeptide chondramides interrupt SARS-CoV-2 entry by targeting its broad, cell tropic spike protein 39
Totale 10.113
Salva come PNG Salva come JPEG
Categoria #
all - tutte 33.803
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33.803
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.292 0 0 0 0 0 0 313 298 316 154 184 27
2020/20211.110 86 82 64 116 45 101 21 88 156 112 110 129
2021/20221.202 42 31 15 20 252 197 35 30 104 58 94 324
2022/2023985 174 155 103 47 78 112 33 40 176 8 32 27
2023/20243.479 92 116 84 82 192 206 127 15 9 2.378 25 153
2024/20251.384 29 157 51 256 287 531 73 0 0 0 0 0
Totale 11.138