CINECA IRIS Institutional Research Information System

BROGI, SIMONE
 Distribuzione geografica
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Continente #
NA - Nord America 7.309
EU - Europa 1.632
AS - Asia 583
AF - Africa 44
SA - Sud America 13
OC - Oceania 7
Continente sconosciuto - Info sul continente non disponibili 6
Totale 9.594
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Nazione #
US - Stati Uniti d'America 4.979
CA - Canada 2.328
IT - Italia 601
SE - Svezia 477
BG - Bulgaria 285
SG - Singapore 242
CN - Cina 153
VN - Vietnam 95
GB - Regno Unito 62
DE - Germania 57
FI - Finlandia 34
HK - Hong Kong 34
CI - Costa d'Avorio 30
BE - Belgio 28
IN - India 19
FR - Francia 18
CH - Svizzera 14
GR - Grecia 13
TR - Turchia 13
PL - Polonia 11
BR - Brasile 10
AU - Australia 6
EU - Europa 6
KR - Corea 6
BD - Bangladesh 5
ES - Italia 5
IE - Irlanda 5
CZ - Repubblica Ceca 4
PK - Pakistan 4
SN - Senegal 4
UA - Ucraina 4
AR - Argentina 3
AT - Austria 3
MU - Mauritius 3
NL - Olanda 3
SA - Arabia Saudita 3
ZA - Sudafrica 3
IR - Iran 2
JP - Giappone 2
MX - Messico 2
NG - Nigeria 2
PT - Portogallo 2
RO - Romania 2
RU - Federazione Russa 2
TW - Taiwan 2
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
EG - Egitto 1
IL - Israele 1
MA - Marocco 1
MY - Malesia 1
NZ - Nuova Zelanda 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 9.594
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Città #
Montreal 2.309
Fairfield 915
Woodbridge 452
Ashburn 432
Seattle 402
Cambridge 334
Wilmington 306
Houston 300
Sofia 284
Milan 276
Boulder 265
Chandler 225
New York 216
Boardman 163
Princeton 118
Lawrence 113
Ann Arbor 106
Singapore 89
Medford 76
Des Moines 59
Dong Ket 51
San Diego 40
Rome 37
Beijing 35
Chicago 34
London 34
Grafing 32
Abidjan 30
Hong Kong 28
Lappeenranta 28
Serra 28
Nanjing 26
Siena 26
Brussels 25
Los Angeles 21
Nanchang 16
Ogden 16
Hebei 14
Falls Church 12
Marseille 11
Norwalk 11
Florence 10
Frankfurt am Main 10
Dearborn 9
Livorno 9
San Jose 9
Warsaw 9
Changsha 8
Shenyang 8
Toronto 7
Bern 6
Dallas 6
Hyderabad 6
Montréal 6
Mumbai 6
Tianjin 6
West Jordan 6
Dublin 5
Hangzhou 5
Helsinki 5
Pisa 5
São Paulo 5
Dakar 4
Guangzhou 4
Izmir 4
Redwood City 4
Brno 3
Castelliri 3
Council Bluffs 3
Dhaka 3
Gujrat 3
Istanbul 3
Madrid 3
Melbourne 3
Napoli 3
North York 3
Ospitaletto 3
Ottawa 3
Pieve 3
Porto Alegre 3
San Piero a Sieve 3
Southwark 3
Tekirdağ 3
Uppsala 3
Vienna 3
Washington 3
Acton 2
Azeitao 2
Ballynahinch 2
Bologna 2
Borås 2
Camaiore 2
Castelar 2
Centrale 2
Clifton 2
Haikou 2
Jeddah 2
Jiaxing 2
Kunming 2
Kyiv 2
Totale 8.245
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Nome #
0365: Non-peptidic prokineticin receptor 1 agonist as a novel cardioprotective therapeutic 2.605
The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1 153
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements and Structural and Biological Investigation 133
NOVEL ANALGESIC/ANTI-INFLAMMATORY AGENTS: 1,5-DIARYLPYRROLE NITROOXYALKYL ETHERS AND RELATED COMPOUNDS AS CYCLOOXYGENASE-2 INHIBITING NITRIC OXIDE DONORS 123
Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages 113
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents 109
Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare Diseases 100
Dealing with schistosomiasis: Current drug discovery strategies 95
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 92
Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA B receptor 89
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain 88
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain 88
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues 85
3D-QSAR using pharmacophore-based alignment and virtual screening for discovery of novel MCF-7 cell line inhibitors 84
Breakthroughs in Computational Approaches for Drug Discovery 84
Dietary polyphenols rutin, taxifolin and quercetin related compounds target: Leishmania amazonensis arginase 84
Rational design of the first difluorostatone-based PfSUB1 inhibitors 81
Cinnamic acids derived compounds with antileishmanial activity target Leishmania amazonensis arginase 81
Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II) 80
Mimicking the intramolecular hydrogen bond: Synthesis, biological evaluation, andmolecular modeling of benzoxazines and quinazolines as potential antimalarial agents 80
Amyloid β fibril disruption by oleuropein aglycone: long-time molecular dynamics simulation to gain insight into the mechanism of action of this polyphenol from extra virgin olive oil 78
Discovery and Cardioprotective Effects of the First Non-Peptide Agonists of the G-Protein-Coupled Prokineticin Receptor-1 77
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: Further structure-activity relationships, in vivo studies, and preliminary toxicity profiling 76
A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision 75
Synthesis and Biological Evaluation of Novel Neuroprotective Pyridazine Derivatives as Excitatory Amino Acid Transporter 2 (EAAT2) Activators 75
Computational Approaches for Drug Discovery 75
Activation of the Wnt Pathway by Small Peptides: Rational Design, Synthesis and Biological Evaluation 75
Pharmacophore modeling for qualitative prediction of antiestrogenic activity 74
Phenylpyrrole-based HDAC inhibitors: Synthesis, molecular modeling and biological studies 74
Exploring clotrimazole-based pharmacophore: 3D-QSAR studies and synthesis of novel antiplasmodial agents 73
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity 73
iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome 73
Plasmodium falciparum subtilisin-like protease 1: Discovery of potent difluorostatone-based inhibitors 72
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems 72
Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2 71
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies 70
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents 70
Identification of novel fluorescent probes preventing PrPScreplication in prion diseases 70
Computational tool for fast in silico evaluation of hERG K+ channel affinity 69
Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: Definition of the structural determinants for enzyme inhibition 69
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1 69
Telomerase-based cancer therapeutics: a review on their clinical trials 69
Discovery and cardioprotective effects of the first non-peptide agonists of the G protein-coupled prokineticin receptor-1 69
Polypharmacology of dopamine receptor ligands 68
Synthesis and structure-activity relationship studies in serotonin 5-HT1A receptor agonists based on fused pyrrolidone scaffolds 68
Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation 68
A stereoselective approach to peptidomimetic BACE1 inhibitors 68
Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease 67
From (+)-epigallocatechin gallate to a simplified synthetic analogue as a cytoadherence inhibitor for P. falciparum 67
Synthetic spirocyclic endoperoxides: New antimalarial scaffolds 67
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents 67
Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: Potent and selective CB2 cannabinoid receptor inverse agonists 67
Synthesis and antiplasmodial activity of bicyclic dioxanes as simplified dihydroplakortin analogues 67
Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal Agents 67
Cinnamides Target Leishmania amazonensis Arginase Selectively 67
Multifunctional cholinesterase and amyloid beta fibrillization modulators. Synthesis and biological investigation 66
Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches to Treat Central Nervous System Disorders 66
Development of HuperTacrines as non-toxic, cholinesterase inhibitors for the potential treatment of Alzheimer’s disease 66
Abstract 411: Discovery and Cardioprotective Effects of the First Non-peptide Agonists of Prokineticin Receptor-1 66
HCV-targeted antivirals: Current status and future challenges 65
Anti-inflammatory and antiviral roles of hydrogen sulfide: Rationale for considering H2S donors in COVID-19 therapy 65
Discovery of iminobenzimidazole derivatives as novel cytotoxic agents 64
Development of novel cyclic peptides as pro-apoptotic agents 64
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 64
Synthesis, Molecular Modelling and Biological Studies of 3-hydroxy-pyrane-4-one and 3-hydroxy-pyridine-4-one Derivatives as HIV-1 Integrase Inhibitors 63
Synthetic studies toward bicyclic endoperoxides presenting polar side chains 63
Development of a practical and scalable route for the preparation of the deacetoxytubuvaline (dTuv) fragment of pretubulysin and analogs 63
In silico study of subtilisin-like protease 1 (SUB1) from different Plasmodium species in complex with peptidyl-difluorostatones and characterization of potent pan-SUB1 inhibitors 63
Discovery of GPCR ligands for probing signal transduction pathways 63
Targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors for developing effective antipsychotics: Synthesis, biological characterization, and behavioral studies 62
A repurposing approach for uncovering the anti-tubercular activity of FDA-approved drugs with Potential Multi-Targeting Profiles 62
Role of hydrogen sulfide in endothelial dysfunction: Pathophysiology and therapeutic approaches 62
Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors 61
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX 61
Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold 61
Organic Isothiocyanates as Hydrogen Sulfide Donors 61
First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents 60
MicroRNA-Based Multitarget Approach for Alzheimer's Disease: Discovery of the First-In-Class Dual Inhibitor of Acetylcholinesterase and MicroRNA-15b Biogenesis 60
Development of In Vitro Corneal Models: Opportunity for Pharmacological Testing 57
An integrated in silico screening strategy for identifying promising disruptors of p53-MDM2 interaction 55
Design, synthesis and biological evaluation of 7-substituted 4-phenyl-6H-imidazo[1,5-a]thieno[3,2-f] [1,4]diazepines as safe anxiolytic agents 52
Identification of novel SIRT1 activators endowed with cardioprotective profile 49
The structural evolution of β-secretase inhibitors: A focus on the development of small-molecule inhibitors 48
Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents 47
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases 47
Verbascoside Inhibits Promastigote Growth and Arginase Activity of Leishmania amazonensis 47
Tetrahydrofuran acetogenins from Laurencia glandulifera 43
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 43
Disease-modifying anti-Alzheimer's drugs: Inhibitors of human cholinesterases interfering with β-amyloid aggregation 42
Computer-Driven Development of an in Silico Tool for Finding Selective Histone Deacetylase 1 Inhibitors 41
Artificial Intelligence in Translational Medicine 39
Role of hydrogen sulfide in cardiovascular ageing 37
Identification of Novel 3-Hydroxy-pyran-4-One Derivatives as Potent HIV-1 Integrase Inhibitors Using in silico Structure-Based Combinatorial Library Design Approach 37
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation 37
IN SILICO METHODS FOR DRUG DESIGN AND DISCOVERY 37
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 36
Computer-based approaches for determining the pharmacological profile of 5-(3-nitro-arylidene)-thiazolidine-2,4-dione 35
Off-target ACE2 ligands: possible therapeutic option for CoVid-19? 33
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, Synthesis, Structural Analysis, and Biological Evaluation 31
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents 31
Totale 9.298
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Categoria #
all - tutte 29.316
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 29.316
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.349 0 0 82 367 308 300 313 298 316 154 184 27
2020/20211.110 86 82 64 116 45 101 21 88 156 112 110 129
2021/20221.202 42 31 15 20 252 197 35 30 104 58 94 324
2022/2023985 174 155 103 47 78 112 33 40 176 8 32 27
2023/20243.479 92 116 84 82 192 206 127 15 9 2.378 25 153
2024/2025212 29 157 26 0 0 0 0 0 0 0 0 0
Totale 9.966