CINECA IRIS Institutional Research Information System

BROGI, SIMONE
 Distribuzione geografica
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Continente #
NA - Nord America 14.882
AS - Asia 4.753
EU - Europa 2.247
SA - Sud America 1.685
AF - Africa 196
OC - Oceania 10
Continente sconosciuto - Info sul continente non disponibili 8
Totale 23.781
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Nazione #
US - Stati Uniti d'America 12.395
CA - Canada 2.380
BR - Brasile 1.378
SG - Singapore 1.352
HK - Hong Kong 1.097
CN - Cina 971
IT - Italia 689
VN - Vietnam 504
SE - Svezia 487
BG - Bulgaria 288
GB - Regno Unito 156
RU - Federazione Russa 135
IN - India 132
DE - Germania 123
TR - Turchia 117
KR - Corea 112
AR - Argentina 104
BD - Bangladesh 87
FI - Finlandia 67
FR - Francia 61
IQ - Iraq 57
EC - Ecuador 48
ZA - Sudafrica 47
MX - Messico 46
ID - Indonesia 45
JP - Giappone 45
AT - Austria 37
SA - Arabia Saudita 37
BE - Belgio 35
PK - Pakistan 34
CI - Costa d'Avorio 33
UZ - Uzbekistan 33
UA - Ucraina 32
VE - Venezuela 30
PE - Perù 29
CO - Colombia 26
PL - Polonia 26
KE - Kenya 25
CL - Cile 21
PY - Paraguay 18
MA - Marocco 17
NL - Olanda 17
NP - Nepal 17
CH - Svizzera 15
ES - Italia 15
UY - Uruguay 15
DZ - Algeria 14
EG - Egitto 14
GR - Grecia 13
IE - Irlanda 13
JO - Giordania 12
TN - Tunisia 12
BO - Bolivia 11
MY - Malesia 11
JM - Giamaica 10
AE - Emirati Arabi Uniti 9
AU - Australia 9
AZ - Azerbaigian 9
BB - Barbados 9
LB - Libano 9
DO - Repubblica Dominicana 8
IL - Israele 8
TT - Trinidad e Tobago 7
TW - Taiwan 7
BH - Bahrain 6
BS - Bahamas 6
EU - Europa 6
IR - Iran 6
SN - Senegal 6
CZ - Repubblica Ceca 5
GY - Guiana 5
HN - Honduras 5
PH - Filippine 5
PT - Portogallo 5
AO - Angola 4
CR - Costa Rica 4
LT - Lituania 4
LY - Libia 4
AL - Albania 3
AM - Armenia 3
ET - Etiopia 3
GA - Gabon 3
KH - Cambogia 3
KW - Kuwait 3
KZ - Kazakistan 3
MK - Macedonia 3
MU - Mauritius 3
NI - Nicaragua 3
OM - Oman 3
PS - Palestinian Territory 3
RO - Romania 3
RS - Serbia 3
BA - Bosnia-Erzegovina 2
BY - Bielorussia 2
GE - Georgia 2
HU - Ungheria 2
KY - Cayman, isole 2
MD - Moldavia 2
MN - Mongolia 2
NG - Nigeria 2
Totale 23.749
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Città #
Dallas 5.936
Montreal 2.313
Hong Kong 1.088
Fairfield 915
Ashburn 772
Singapore 655
Santa Clara 514
Woodbridge 452
Seattle 406
Cambridge 334
Wilmington 306
Shanghai 303
Houston 302
Sofia 285
Milan 282
Boulder 265
New York 234
Chandler 225
Boardman 169
Los Angeles 168
Hefei 152
Ho Chi Minh City 150
Princeton 118
Lawrence 113
Ann Arbor 106
Beijing 106
Seoul 105
São Paulo 103
Istanbul 86
Medford 76
Hanoi 74
Des Moines 71
Chicago 59
Buffalo 54
Dong Ket 51
London 46
Rio de Janeiro 46
Rome 46
Redondo Beach 43
Lappeenranta 40
San Diego 40
Tokyo 38
San Jose 37
Brasília 34
Abidjan 33
Grafing 32
Serra 31
Tashkent 31
Belo Horizonte 30
Quanzhou 30
Brussels 28
Curitiba 26
Frankfurt am Main 26
Nanjing 26
Siena 26
Baghdad 24
Dhaka 24
Porto Alegre 23
Nuremberg 22
Johannesburg 21
Lima 21
Nairobi 21
North Bergen 21
Munich 20
Quito 20
Vienna 20
Fuzhou 19
Livorno 19
Warsaw 19
Florence 18
Thái Bình 18
Da Nang 16
Haiphong 16
Manaus 16
Nanchang 16
Ogden 16
Salvador 16
Biên Hòa 15
Hyderabad 15
Riyadh 15
Guayaquil 14
Hebei 14
Helsinki 14
Pisa 14
Toronto 14
Council Bluffs 13
Montevideo 13
Sorocaba 13
Xiamen 13
Amman 12
Falls Church 12
Jeddah 12
Mumbai 12
Turku 12
Caxias do Sul 11
Dublin 11
Lahore 11
Lucca 11
Marseille 11
New Delhi 11
Totale 18.756
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Nome #
0365: Non-peptidic prokineticin receptor 1 agonist as a novel cardioprotective therapeutic 8.414
The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1 226
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements and Structural and Biological Investigation 201
Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages 187
NOVEL ANALGESIC/ANTI-INFLAMMATORY AGENTS: 1,5-DIARYLPYRROLE NITROOXYALKYL ETHERS AND RELATED COMPOUNDS AS CYCLOOXYGENASE-2 INHIBITING NITRIC OXIDE DONORS 157
Dealing with schistosomiasis: Current drug discovery strategies 155
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain 152
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues 151
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain 151
Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare Diseases 151
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents 148
Exploring clotrimazole-based pharmacophore: 3D-QSAR studies and synthesis of novel antiplasmodial agents 145
iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome 145
Mimicking the intramolecular hydrogen bond: Synthesis, biological evaluation, andmolecular modeling of benzoxazines and quinazolines as potential antimalarial agents 145
Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: Definition of the structural determinants for enzyme inhibition 144
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 144
Pharmacophore modeling for qualitative prediction of antiestrogenic activity 142
From (+)-epigallocatechin gallate to a simplified synthetic analogue as a cytoadherence inhibitor for P. falciparum 142
Identification of novel fluorescent probes preventing PrPScreplication in prion diseases 142
Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal Agents 142
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: Further structure-activity relationships, in vivo studies, and preliminary toxicity profiling 141
Discovery and Cardioprotective Effects of the First Non-Peptide Agonists of the G-Protein-Coupled Prokineticin Receptor-1 140
A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision 140
Synthesis and Biological Evaluation of Novel Neuroprotective Pyridazine Derivatives as Excitatory Amino Acid Transporter 2 (EAAT2) Activators 140
Breakthroughs in Computational Approaches for Drug Discovery 140
Resveratrol-like Compounds as SIRT1 Activators 139
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents 139
Polypharmacology of dopamine receptor ligands 138
Computational Approaches for Drug Discovery 138
Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2 137
Phenylpyrrole-based HDAC inhibitors: Synthesis, molecular modeling and biological studies 137
Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II) 136
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies 134
Dietary polyphenols rutin, taxifolin and quercetin related compounds target: Leishmania amazonensis arginase 133
Cinnamides Target Leishmania amazonensis Arginase Selectively 133
In silico study of subtilisin-like protease 1 (SUB1) from different Plasmodium species in complex with peptidyl-difluorostatones and characterization of potent pan-SUB1 inhibitors 132
Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches to Treat Central Nervous System Disorders 132
A stereoselective approach to peptidomimetic BACE1 inhibitors 132
Plasmodium falciparum subtilisin-like protease 1: Discovery of potent difluorostatone-based inhibitors 132
Computational tool for fast in silico evaluation of hERG K+ channel affinity 131
Synthesis and structure-activity relationship studies in serotonin 5-HT1A receptor agonists based on fused pyrrolidone scaffolds 131
A repurposing approach for uncovering the anti-tubercular activity of FDA-approved drugs with Potential Multi-Targeting Profiles 131
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 131
Cinnamic acids derived compounds with antileishmanial activity target Leishmania amazonensis arginase 130
Discovery of iminobenzimidazole derivatives as novel cytotoxic agents 130
Development of a practical and scalable route for the preparation of the deacetoxytubuvaline (dTuv) fragment of pretubulysin and analogs 130
Development of novel cyclic peptides as pro-apoptotic agents 129
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity 129
Targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors for developing effective antipsychotics: Synthesis, biological characterization, and behavioral studies 128
3D-QSAR using pharmacophore-based alignment and virtual screening for discovery of novel MCF-7 cell line inhibitors 128
Telomerase-based cancer therapeutics: a review on their clinical trials 128
Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: Potent and selective CB2 cannabinoid receptor inverse agonists 127
Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation 127
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems 127
Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents 125
Synthesis and antiplasmodial activity of bicyclic dioxanes as simplified dihydroplakortin analogues 125
HCV-targeted antivirals: Current status and future challenges 123
Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold 123
Amyloid β fibril disruption by oleuropein aglycone: long-time molecular dynamics simulation to gain insight into the mechanism of action of this polyphenol from extra virgin olive oil 123
Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA B receptor 121
Synthetic studies toward bicyclic endoperoxides presenting polar side chains 121
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 121
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents 120
Rational design of the first difluorostatone-based PfSUB1 inhibitors 119
First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents 119
Discovery of GPCR ligands for probing signal transduction pathways 119
MicroRNA-Based Multitarget Approach for Alzheimer's Disease: Discovery of the First-In-Class Dual Inhibitor of Acetylcholinesterase and MicroRNA-15b Biogenesis 119
Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease 118
Synthetic spirocyclic endoperoxides: New antimalarial scaffolds 118
Discovery and cardioprotective effects of the first non-peptide agonists of the G protein-coupled prokineticin receptor-1 118
Synthesis, Molecular Modelling and Biological Studies of 3-hydroxy-pyrane-4-one and 3-hydroxy-pyridine-4-one Derivatives as HIV-1 Integrase Inhibitors 116
Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors 116
Verbascoside Inhibits Promastigote Growth and Arginase Activity of Leishmania amazonensis 115
Activation of the Wnt Pathway by Small Peptides: Rational Design, Synthesis and Biological Evaluation 115
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1 114
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation 114
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX 113
An integrated in silico screening strategy for identifying promising disruptors of p53-MDM2 interaction 113
Development of HuperTacrines as non-toxic, cholinesterase inhibitors for the potential treatment of Alzheimer’s disease 112
Multifunctional cholinesterase and amyloid beta fibrillization modulators. Synthesis and biological investigation 111
Design, synthesis and biological evaluation of 7-substituted 4-phenyl-6H-imidazo[1,5-a]thieno[3,2-f] [1,4]diazepines as safe anxiolytic agents 111
Role of hydrogen sulfide in endothelial dysfunction: Pathophysiology and therapeutic approaches 110
Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy 108
Organic Isothiocyanates as Hydrogen Sulfide Donors 107
Luteolin-Induced Activation of Mitochondrial BKCa Channels: Undisclosed Mechanism of Cytoprotection 106
Disease-modifying anti-Alzheimer's drugs: Inhibitors of human cholinesterases interfering with β-amyloid aggregation 106
Abstract 411: Discovery and Cardioprotective Effects of the First Non-peptide Agonists of Prokineticin Receptor-1 106
Role of hydrogen sulfide in cardiovascular ageing 104
The structural evolution of β-secretase inhibitors: A focus on the development of small-molecule inhibitors 101
Characterization of stenocephol from Seriphidium stenocephalum as potent HepG2 cell growth and glycogen phosphorylase inhibitor 98
Computer-based approaches for determining the pharmacological profile of 5-(3-nitro-arylidene)-thiazolidine-2,4-dione 96
Tetrahydrofuran acetogenins from Laurencia glandulifera 95
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases 93
IN SILICO METHODS FOR DRUG DESIGN AND DISCOVERY 93
Identification of novel SIRT1 activators endowed with cardioprotective profile 93
Anti-inflammatory and antiviral roles of hydrogen sulfide: Rationale for considering H2S donors in COVID-19 therapy 87
Identification of Novel 3-Hydroxy-pyran-4-One Derivatives as Potent HIV-1 Integrase Inhibitors Using in silico Structure-Based Combinatorial Library Design Approach 87
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 87
Development of In Vitro Corneal Models: Opportunity for Pharmacological Testing 86
Development of Quinazolinone Derivatives as Modulators of Virulence Factors of Pseudomonas aeruginosa Cystic Fibrosis Strains 85
Totale 20.944
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Categoria #
all - tutte 56.858
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 56.858
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021616 0 0 0 0 0 0 21 88 156 112 110 129
2021/20221.202 42 31 15 20 252 197 35 30 104 58 94 324
2022/2023985 174 155 103 47 78 112 33 40 176 8 32 27
2023/20243.479 92 116 84 82 192 206 127 15 9 2.378 25 153
2024/20255.141 29 157 51 256 287 531 391 243 499 549 535 1.613
2025/20269.351 203 2.127 4.919 1.244 381 443 34 0 0 0 0 0
Totale 24.246