CINECA IRIS Institutional Research Information System

BROGI, SIMONE
 Distribuzione geografica
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Continente #
NA - Nord America 16.073
AS - Asia 5.447
EU - Europa 2.656
SA - Sud America 1.785
AF - Africa 232
OC - Oceania 12
Continente sconosciuto - Info sul continente non disponibili 8
Totale 26.213
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Nazione #
US - Stati Uniti d'America 13.531
CA - Canada 2.406
SG - Singapore 1.600
BR - Brasile 1.435
HK - Hong Kong 1.115
CN - Cina 1.077
IT - Italia 831
VN - Vietnam 609
SE - Svezia 510
BG - Bulgaria 289
FR - Francia 181
IN - India 170
GB - Regno Unito 166
DE - Germania 142
RU - Federazione Russa 140
TR - Turchia 125
AR - Argentina 120
KR - Corea 113
BD - Bangladesh 103
JP - Giappone 100
FI - Finlandia 96
IQ - Iraq 76
ID - Indonesia 57
MX - Messico 57
ZA - Sudafrica 56
EC - Ecuador 50
SA - Arabia Saudita 46
PK - Pakistan 45
UA - Ucraina 39
UZ - Uzbekistan 39
AT - Austria 38
VE - Venezuela 37
BE - Belgio 36
CO - Colombia 35
CH - Svizzera 34
CI - Costa d'Avorio 33
PE - Perù 29
PL - Polonia 28
KE - Kenya 27
NL - Olanda 27
CL - Cile 25
MA - Marocco 23
ES - Italia 21
PY - Paraguay 20
NP - Nepal 19
TN - Tunisia 19
EG - Egitto 17
UY - Uruguay 17
DZ - Algeria 15
MY - Malesia 15
GR - Grecia 14
JO - Giordania 14
BB - Barbados 13
IE - Irlanda 13
JM - Giamaica 13
PH - Filippine 13
BO - Bolivia 12
AZ - Azerbaigian 11
AE - Emirati Arabi Uniti 10
AU - Australia 10
IL - Israele 10
LB - Libano 10
DO - Repubblica Dominicana 9
TT - Trinidad e Tobago 8
TW - Taiwan 8
HN - Honduras 7
RS - Serbia 7
SN - Senegal 7
AM - Armenia 6
BH - Bahrain 6
BS - Bahamas 6
CR - Costa Rica 6
CZ - Repubblica Ceca 6
EU - Europa 6
IR - Iran 6
KZ - Kazakistan 6
PT - Portogallo 6
ET - Etiopia 5
GY - Guiana 5
LT - Lituania 5
OM - Oman 5
PS - Palestinian Territory 5
RO - Romania 5
SY - Repubblica araba siriana 5
AL - Albania 4
AO - Angola 4
KG - Kirghizistan 4
KH - Cambogia 4
LY - Libia 4
MD - Moldavia 4
SV - El Salvador 4
BY - Bielorussia 3
GA - Gabon 3
KW - Kuwait 3
MK - Macedonia 3
MU - Mauritius 3
NG - Nigeria 3
NI - Nicaragua 3
BA - Bosnia-Erzegovina 2
GE - Georgia 2
Totale 26.170
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Città #
Dallas 5.946
Montreal 2.315
Hong Kong 1.104
Fairfield 915
Ashburn 880
Singapore 851
San Jose 660
Santa Clara 523
Woodbridge 452
Seattle 408
Cambridge 334
Milan 308
Houston 306
Wilmington 306
Shanghai 303
Sofia 285
Boulder 265
New York 242
Chandler 225
Los Angeles 185
Ho Chi Minh City 182
Boardman 173
Hefei 152
Beijing 119
Princeton 118
Lawrence 113
Lauterbourg 108
São Paulo 107
Ann Arbor 106
Seoul 105
Hanoi 98
Istanbul 90
Tokyo 90
Council Bluffs 76
Medford 76
Des Moines 72
Chicago 67
Buffalo 56
Rome 55
Dong Ket 51
Rio de Janeiro 49
London 46
Redondo Beach 43
San Diego 43
Helsinki 42
Frankfurt am Main 41
Lappeenranta 41
Tashkent 37
Brasília 35
Abidjan 33
Grafing 32
Serra 32
Baghdad 31
Belo Horizonte 30
Quanzhou 30
Brussels 29
Curitiba 27
Dhaka 26
Nanjing 26
Siena 26
Haiphong 23
Nairobi 23
Porto Alegre 23
Florence 22
Johannesburg 22
Nuremberg 22
Lima 21
North Bergen 21
Quito 21
Munich 20
Pisa 20
Thái Bình 20
Vienna 20
Warsaw 20
Da Nang 19
Fuzhou 19
Livorno 19
Zurich 19
Biên Hòa 17
Hyderabad 17
Jeddah 17
Orem 17
Paris 17
Riyadh 17
Manaus 16
Nanchang 16
Ogden 16
Salvador 16
Toronto 16
Guayaquil 15
Montevideo 15
Amman 14
Chennai 14
Hebei 14
Mumbai 14
Xiamen 14
Lahore 13
Naples 13
Sorocaba 13
Denver 12
Totale 20.233
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Nome #
0365: Non-peptidic prokineticin receptor 1 agonist as a novel cardioprotective therapeutic 8.463
The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1 258
Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages 223
(S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements and Structural and Biological Investigation 221
Resveratrol-like Compounds as SIRT1 Activators 195
H2S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma 170
Dealing with schistosomiasis: Current drug discovery strategies 168
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain 166
NOVEL ANALGESIC/ANTI-INFLAMMATORY AGENTS: 1,5-DIARYLPYRROLE NITROOXYALKYL ETHERS AND RELATED COMPOUNDS AS CYCLOOXYGENASE-2 INHIBITING NITRIC OXIDE DONORS 165
Mimicking the intramolecular hydrogen bond: Synthesis, biological evaluation, andmolecular modeling of benzoxazines and quinazolines as potential antimalarial agents 165
Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: Definition of the structural determinants for enzyme inhibition 163
Targeting Relevant HDACs to Support the Survival of Cone Photoreceptors in Inherited Retinal Diseases: Identification of a Potent Pharmacological Tool with In Vitro and In Vivo Efficacy 162
Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues 162
iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome 162
Cinnamides Target Leishmania amazonensis Arginase Selectively 162
Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain 160
Exploring clotrimazole-based pharmacophore: 3D-QSAR studies and synthesis of novel antiplasmodial agents 160
Synthesis and Biological Evaluation of Novel Neuroprotective Pyridazine Derivatives as Excitatory Amino Acid Transporter 2 (EAAT2) Activators 160
Old but Gold: Tracking the New Guise of Histone Deacetylase 6 (HDAC6) Enzyme as a Biomarker and Therapeutic Target in Rare Diseases 160
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents 160
A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents 159
Identification of novel fluorescent probes preventing PrPScreplication in prion diseases 158
Breakthroughs in Computational Approaches for Drug Discovery 156
Phenylpyrrole-based HDAC inhibitors: Synthesis, molecular modeling and biological studies 156
Polypharmacology of dopamine receptor ligands 155
Allosteric Modulation of Ionotropic Glutamate Receptors: An Outlook on New Therapeutic Approaches to Treat Central Nervous System Disorders 155
A light in the dark: State of the art and perspectives in optogenetics and optopharmacology for restoring vision 154
Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2 154
3D-QSAR using pharmacophore-based alignment and virtual screening for discovery of novel MCF-7 cell line inhibitors 153
Structure-activity relationships study of isothiocyanates for H2S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent 153
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: Further structure-activity relationships, in vivo studies, and preliminary toxicity profiling 152
A stereoselective approach to peptidomimetic BACE1 inhibitors 152
Computational tool for fast in silico evaluation of hERG K+ channel affinity 151
From (+)-epigallocatechin gallate to a simplified synthetic analogue as a cytoadherence inhibitor for P. falciparum 151
Pharmacophore modeling for qualitative prediction of antiestrogenic activity 150
Development of a practical and scalable route for the preparation of the deacetoxytubuvaline (dTuv) fragment of pretubulysin and analogs 150
Computational Approaches for Drug Discovery 149
Discovery and Cardioprotective Effects of the First Non-Peptide Agonists of the G-Protein-Coupled Prokineticin Receptor-1 148
Development of novel cyclic peptides as pro-apoptotic agents 148
Plasmodium falciparum subtilisin-like protease 1: Discovery of potent difluorostatone-based inhibitors 148
In silico study of subtilisin-like protease 1 (SUB1) from different Plasmodium species in complex with peptidyl-difluorostatones and characterization of potent pan-SUB1 inhibitors 147
A repurposing approach for uncovering the anti-tubercular activity of FDA-approved drugs with Potential Multi-Targeting Profiles 147
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity 145
Dietary polyphenols rutin, taxifolin and quercetin related compounds target: Leishmania amazonensis arginase 145
Bridged bicyclic 2,3-dioxabicyclo[3.3.1]nonanes as antiplasmodial agents: Synthesis, structure-activity relationships and studies on their biomimetic reaction with Fe(II) 144
Cinnamic acids derived compounds with antileishmanial activity target Leishmania amazonensis arginase 144
Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: Potent and selective CB2 cannabinoid receptor inverse agonists 144
Donepezil-like multifunctional agents: Design, synthesis, molecular modeling and biological evaluation 144
Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal Agents 143
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies 142
Discovery of iminobenzimidazole derivatives as novel cytotoxic agents 142
Targeting dopamine D3 and serotonin 5-HT1A and 5-HT2A receptors for developing effective antipsychotics: Synthesis, biological characterization, and behavioral studies 140
Synthesis and structure-activity relationship studies in serotonin 5-HT1A receptor agonists based on fused pyrrolidone scaffolds 139
Synthesis and antiplasmodial activity of bicyclic dioxanes as simplified dihydroplakortin analogues 138
Design, synthesis, and biological investigation of oxadiazolyl, thiadiazolyl, and pyrimidinyl linked antipyrine derivatives as potential non-acidic anti-inflammatory agents 137
Synthetic studies toward bicyclic endoperoxides presenting polar side chains 137
Structure-based discovery of the first non-covalent inhibitors of Leishmania major tryparedoxin peroxidase by high throughput docking 137
Verbascoside Inhibits Promastigote Growth and Arginase Activity of Leishmania amazonensis 137
Synthesis and biological evaluation of a new class of benzothiazines as neuroprotective agents 135
Discovery of GPCR ligands for probing signal transduction pathways 135
Telomerase-based cancer therapeutics: a review on their clinical trials 135
Discovery and cardioprotective effects of the first non-peptide agonists of the G protein-coupled prokineticin receptor-1 135
Synthetic spirocyclic endoperoxides: New antimalarial scaffolds 134
HCV-targeted antivirals: Current status and future challenges 133
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems 133
First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents 132
Role of hydrogen sulfide in endothelial dysfunction: Pathophysiology and therapeutic approaches 129
Characterization of COR627 and COR628, two novel positive allosteric modulators of the GABA B receptor 128
Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1 128
Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold 128
Luteolin-Induced Activation of Mitochondrial BKCa Channels: Undisclosed Mechanism of Cytoprotection 126
Rational design of the first difluorostatone-based PfSUB1 inhibitors 126
Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease 126
Development of HuperTacrines as non-toxic, cholinesterase inhibitors for the potential treatment of Alzheimer’s disease 126
Amyloid β fibril disruption by oleuropein aglycone: long-time molecular dynamics simulation to gain insight into the mechanism of action of this polyphenol from extra virgin olive oil 126
Synthesis, Molecular Modelling and Biological Studies of 3-hydroxy-pyrane-4-one and 3-hydroxy-pyridine-4-one Derivatives as HIV-1 Integrase Inhibitors 125
Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors 125
Multifunctional cholinesterase and amyloid beta fibrillization modulators. Synthesis and biological investigation 125
Organic Isothiocyanates as Hydrogen Sulfide Donors 125
MicroRNA-Based Multitarget Approach for Alzheimer's Disease: Discovery of the First-In-Class Dual Inhibitor of Acetylcholinesterase and MicroRNA-15b Biogenesis 125
Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation 125
Disease-modifying anti-Alzheimer's drugs: Inhibitors of human cholinesterases interfering with β-amyloid aggregation 124
Structural characterization of Giardia duodenalis thioredoxin reductase (gTrxR) and computational analysis of its interaction with NBDHEX 122
An integrated in silico screening strategy for identifying promising disruptors of p53-MDM2 interaction 120
Activation of the Wnt Pathway by Small Peptides: Rational Design, Synthesis and Biological Evaluation 120
Design, synthesis and biological evaluation of 7-substituted 4-phenyl-6H-imidazo[1,5-a]thieno[3,2-f] [1,4]diazepines as safe anxiolytic agents 119
Discovery of novel hit compounds as potential HDAC1 inhibitors: The case of ligand- and structure-based virtual screening 119
Role of hydrogen sulfide in cardiovascular ageing 117
Characterization of stenocephol from Seriphidium stenocephalum as potent HepG2 cell growth and glycogen phosphorylase inhibitor 115
The structural evolution of β-secretase inhibitors: A focus on the development of small-molecule inhibitors 113
IN SILICO METHODS FOR DRUG DESIGN AND DISCOVERY 113
Abstract 411: Discovery and Cardioprotective Effects of the First Non-peptide Agonists of Prokineticin Receptor-1 112
Computer-based approaches for determining the pharmacological profile of 5-(3-nitro-arylidene)-thiazolidine-2,4-dione 107
New Visions on Natural Products and Cancer Therapy: Autophagy and Related Regulatory Pathways 106
Identification of novel SIRT1 activators endowed with cardioprotective profile 106
Tetrahydrofuran acetogenins from Laurencia glandulifera 104
Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability 104
Globospiramine from Voacanga globosa Exerts Robust Cytotoxic and Antiproliferative Activities on Cancer Cells by Inducing Caspase-Dependent Apoptosis in A549 Cells and Inhibiting MAPK14 (p38α): In Vitro and Computational Investigations 102
Intermittent Fasting: Myths, Fakes and Truth on This Dietary Regimen Approach 100
Dopamine D3 receptor antagonists as potential therapeutics for the treatment of neurological diseases 97
Totale 22.494
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Categoria #
all - tutte 63.400
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 63.400
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021129 0 0 0 0 0 0 0 0 0 0 0 129
2021/20221.202 42 31 15 20 252 197 35 30 104 58 94 324
2022/2023985 174 155 103 47 78 112 33 40 176 8 32 27
2023/20243.479 92 116 84 82 192 206 127 15 9 2.378 25 153
2024/20255.141 29 157 51 256 287 531 391 243 499 549 535 1.613
2025/202611.800 203 2.127 4.919 1.244 381 443 589 354 364 778 213 185
Totale 26.695