DANIELE, SIMONA
 Distribuzione geografica
Continente #
NA - Nord America 13.762
AS - Asia 6.992
EU - Europa 6.469
SA - Sud America 908
AF - Africa 415
OC - Oceania 30
Continente sconosciuto - Info sul continente non disponibili 3
Totale 28.579
Nazione #
US - Stati Uniti d'America 13.335
IT - Italia 2.808
SG - Singapore 2.175
CN - Cina 1.928
HK - Hong Kong 1.073
VN - Vietnam 822
BR - Brasile 749
DE - Germania 729
SE - Svezia 722
BG - Bulgaria 401
GB - Regno Unito 328
FR - Francia 318
CA - Canada 308
FI - Finlandia 271
AT - Austria 220
RU - Federazione Russa 209
TR - Turchia 200
JP - Giappone 149
IN - India 133
KR - Corea 118
SN - Senegal 111
NG - Nigeria 101
UA - Ucraina 91
CI - Costa d'Avorio 72
MX - Messico 72
CH - Svizzera 64
NL - Olanda 59
PL - Polonia 53
IQ - Iraq 49
BD - Bangladesh 46
AR - Argentina 45
BE - Belgio 42
PK - Pakistan 41
ZA - Sudafrica 39
ES - Italia 37
ID - Indonesia 36
CO - Colombia 28
AU - Australia 26
UZ - Uzbekistan 26
GR - Grecia 25
IR - Iran 23
SA - Arabia Saudita 23
MA - Marocco 22
MY - Malesia 22
EC - Ecuador 21
EG - Egitto 20
VE - Venezuela 18
AE - Emirati Arabi Uniti 17
UY - Uruguay 17
PH - Filippine 16
JO - Giordania 15
LT - Lituania 14
IE - Irlanda 13
KE - Kenya 12
CZ - Repubblica Ceca 11
RO - Romania 11
AZ - Azerbaigian 10
CL - Cile 10
IL - Israele 10
JM - Giamaica 9
NP - Nepal 9
PE - Perù 8
TN - Tunisia 8
TW - Taiwan 8
PY - Paraguay 7
AL - Albania 6
BB - Barbados 6
DZ - Algeria 6
GT - Guatemala 6
HU - Ungheria 6
PT - Portogallo 6
CR - Costa Rica 5
GE - Georgia 5
HN - Honduras 5
KZ - Kazakistan 5
NI - Nicaragua 5
BF - Burkina Faso 4
BH - Bahrain 4
BO - Bolivia 4
DK - Danimarca 4
DO - Repubblica Dominicana 4
LA - Repubblica Popolare Democratica del Laos 4
MD - Moldavia 4
NZ - Nuova Zelanda 4
BJ - Benin 3
KG - Kirghizistan 3
LB - Libano 3
OM - Oman 3
PS - Palestinian Territory 3
TT - Trinidad e Tobago 3
A1 - Anonimo 2
BA - Bosnia-Erzegovina 2
BN - Brunei Darussalam 2
BY - Bielorussia 2
CG - Congo 2
EE - Estonia 2
GA - Gabon 2
HR - Croazia 2
KH - Cambogia 2
LV - Lettonia 2
Totale 28.544
Città #
Ashburn 1.310
Serra 1.176
Singapore 1.143
Dallas 1.067
Hong Kong 1.046
Houston 1.036
Woodbridge 1.016
Ann Arbor 857
Fairfield 832
Chandler 725
San Jose 725
Santa Clara 610
Shanghai 401
Sofia 399
Beijing 386
Seattle 385
New York 304
Wilmington 298
Cambridge 293
Milan 289
Boardman 267
Ho Chi Minh City 239
Ottawa 229
Princeton 207
Los Angeles 197
Vienna 195
Hefei 188
Council Bluffs 175
Hanoi 158
Lawrence 149
Lauterbourg 144
Chicago 141
Medford 138
Tokyo 133
Frankfurt am Main 127
Pisa 125
Des Moines 113
Dakar 111
Helsinki 109
Nanjing 108
Seoul 103
Florence 99
London 99
Lagos 98
Munich 93
Dearborn 92
Istanbul 91
Jacksonville 88
Izmir 77
Redondo Beach 76
Abidjan 72
Buffalo 72
Rome 67
Lucca 66
Dong Ket 57
Livorno 57
São Paulo 54
Lancaster 47
Columbus 46
Bremen 43
Nanchang 42
The Dalles 42
Brussels 41
Turku 41
Da Nang 40
Guangzhou 40
Rho 40
Warsaw 40
Redwood City 39
Ogden 38
Alessandria 37
Boulder 36
Orem 36
Zurich 36
Nuremberg 35
San Diego 35
Kunming 31
Phoenix 31
Fuzhou 29
Kent 29
Falls Church 28
Toronto 27
Washington 27
Haiphong 26
Shenyang 25
Montreal 24
Changsha 23
Paris 23
Bologna 22
San Francisco 22
Naples 21
Tianjin 21
Atlanta 20
Hebei 20
Jiaxing 20
Marseille 20
Tashkent 20
Brooklyn 19
Düsseldorf 19
Mexico City 19
Totale 20.232
Nome #
Platelet uptake of GABA and glutamate in patients with bipolar disorder. 402
METODO PER LA DIAGNOSI DI MALATTIE NEURODEGENERATIVE 332
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 309
α-Synuclein Aggregates with β-Amyloid or Tau in Human Red Blood Cells: Correlation with Antioxidant Capability and Physical Exercise in Human Healthy Subjects 305
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 301
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 300
Antioxidant Capability and Physical Exercise in Neurobiology: A Focus in Neurodegeneration 285
Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma 275
α-Synuclein Aggregated with Tau and β-Amyloid in Human Platelets from Healthy Subjects: Correlation with Physical Exercise 272
Studio sui trasportatori di GABA e glutammato nelle piastrine di soggetti con disturbo bipolare 265
New insights into the anticancer activity of carnosol: P53 reactivation in the U87MG human glioblastoma cell line 258
G PROTEIN-COUPLED RECEPTOR DESENSITISATION REGULATES STEM CELL DIFFERENTIATION 257
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells 253
An in vitro comparative study of the antioxidant activity and SIRT1 modulation of natural compounds 251
A2A adenosine receptor binding parameters in platelets from patients affected by pathological gambling 247
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 242
An antibody-free strategy for screening putative HDM2 inhibitors using crude bacterial lysates expressing GST-HDM2 recombinant protein 237
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 234
Apolipoprotein E ε4 triggers neurotoxicity via cholesterol accumulation, acetylcholine dyshomeostasis, and PKCε mislocalization in cholinergic neuronal cells 233
Osteogenesis Is Improved by Low Tumor Necrosis Factor Alpha Concentration through the Modulation of Gs-Coupled Receptor Signals 232
α-Synuclein Heterocomplexes with β-Amyloid Are Increased in Red Blood Cells of Parkinson's Disease Patients and Correlate with Disease Severity 232
Allosteric modulators of human A2B adenosine receptor. 231
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 231
Effect of Ribes nigrum bud extract on human gingival mesenchymal stem cell cytokine release: a role on regenerative processes 230
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 228
Memantine prodrug as a new agent for alzheimer’s disease 223
Protective effect of high-dose montelukast on salbutamol-induced homologous desensitisation in airway smooth muscle. 222
Physical Exercise Improves Total Antioxidant Capacity and Gene Expression in Rat Hippocampal Tissue 221
Carnosol controls the human glioblastoma stemness features through the epithelial-mesenchymal transition modulation and the induction of cancer stem cell apoptosis 217
A mixed-valence diruthenium(ii,iii) complex endowed with high stability: from experimental evidence to theoretical interpretation 214
α-Synuclein Heteromers in Red Blood Cells of Alzheimer's Disease and Lewy Body Dementia Patients 214
Prodromal Intestinal Events in Alzheimer's Disease (AD): Colonic Dysmotility and Inflammation Are Associated with Enteric AD-Related Protein Deposition 213
Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts 212
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: A Novel Template for the Design of Highly Selective A(2B) Adenosine Receptor Antagonists. 207
New 3-, 8-disubstituted pyrazolo[5,1-c][1,2,4]benzotriazines useful for studying the interaction with the HBp-3 area (hydrogen bond point area) in the benzodiazepine site on the γ-aminobutyric acid type A (GABAA) receptor 206
Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death 206
Trazodone treatment protects neuronal-like cells from inflammatory insult by inhibiting NF-κB, p38 and JNK 206
Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease 202
Epigenetic Modifications of the α-Synuclein Gene and Relative Protein Content Are Affected by Ageing and Physical Exercise in Blood from Healthy Subjects 201
The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization 196
Apolipoprotein E Polymorphism and Oxidative Stress in Human Peripheral Blood Cells: Can Physical Activity Reactivate the Proteasome System through Epigenetic Mechanisms? 194
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A(2B) adenosine receptor antagonists 193
Effects of long-term vegan diet on breath composition 193
What Does the Brain Have to Keep Working at Its Best? Resilience Mechanisms Such as Antioxidants and Brain/Cognitive Reserve for Counteracting Alzheimer's Disease Degeneration 192
Endometrial dysbiosis is related to inflammatory factors in women with repeated implantation failure: a pilot study 191
Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: The use of natural compounds as modulatory agents 191
Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators. 190
Novel fluorescent triazinobenzimidazole derivatives as probes for labelling human A1 and A2B adenosine receptor subtypes 188
3-(Fur-2-yl)-10-(2-Phenylethyl)-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one, a Novel Adenosine Receptor Antagonist with (2A)-Mediated Neuroprotective EffeCTS 187
A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer 187
Human glioblastoma multiforme: p53 reactivation by a novel MDM2 inhibitor 186
The A2B adenosine receptor modulates the epithelial- mesenchymal transition through the balance of cAMP/PKA and MAPK/ERK pathway activation in human epithelial lung cells 186
Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists. 184
Novel N(2)-Substituted Pyrazolo[3,4-d]pyrimidine Adenosine A(3) Receptor Antagonists: Inhibition of A(3)-Mediated Human Glioblastoma Cell Proliferation (dagger) 183
Human Neural Stem Cell Aging Is Counteracted by α-Glycerylphosphorylethanolamine 182
Modulation of A2B adenosine receptor by 1-benzyl-3-ketoindole derivatives 182
Adenosine receptors: what we know and what we are learning 180
New Insight into the Central Benzodiazepine Receptor-Ligand Interactions: Design, Synthesis, Biological Evaluation, and Molecular Modeling of 3-Substituted 6-Phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and Related Compounds 179
Modulation of A2B Adenosine Receptor by 1-Benzyl-3-ketoindole Derivatives 179
Discovery of the First-in-Class Dual TSPO/Carbonic Anhydrase Modulators with Promising Neurotrophic Activity 179
Impact of ApoE Polymorphism and Physical Activity on Plasma Antioxidant Capability and Erythrocyte Membranes 177
Does GRK-β arrestin machinery work as a "switch on" for GPR17-mediated activation of intracellular signaling pathways? 175
The oral reversibly-binding antiplatelet agent, Ticagrelor, acts as an antagonist at the P2Y-like receptor GPR17 174
A1 AND A2B ADENOSINE RECEPTORS REGULATE GLIOBLASTOMA STEM CELL DIFFERENTIATION/SURVIVAL AND SENSITIZE CELLS TO CHEMOTHERAPY 172
Long lasting MDM2/Translocator protein modulator: a new strategy for irreversible apoptosis of human glioblastoma cells 170
High Levels of β-Amyloid, Tau, and Phospho-Tau in Red Blood Cells as Biomarkers of Neuropathology in Senescence-Accelerated Mouse 169
Sex Differences in Blood Accumulation of Neurodegenerative-Related Proteins and Antioxidant Responses to Regular Physical Exercise 168
Allosteric modulation of A2B adenosine receptors potentiate the effects of orthosteric receptor agonists to promote mesenchymal stem cell differentiation to osteoblasts. 167
A specific combination of nutraceutical Ingredients exerts cytoprotective effects in human cholinergic neurons 165
Agonist-Induced Desensitization/Resensitization of Human G Protein-Coupled Receptor 17: A Functional Cross-Talk between Purinergic and Cysteinyl-Leukotriene Ligands 165
A rapid and efficient immunoenzymatic assay to detect receptor protein interactions: g protein-coupled receptors. 165
Compounds with a benzo [a]carbazole structure for use in the prevention and/or treatment of infectious diseases 163
A promiscuous recognition mechanism between GPR17 and SDF-1: Molecular insights 163
KEEP A WATCHFUL EYE ON CYRCADIAN RHYTHM AND BRAIN WELLNESS 162
Exploring Epithelial-Mesenchymal Transition Signals in Endometriosis Diagnosis and In Vitro Fertilization Outcomes 162
Translocator protein (TSPO) and identification of new molecular diagnosis tools 161
Modulation of PAR(1) signaling by benzimidazole compounds 159
TUMOR NECROSIS FACTOR ALPHA TRIGGERS OSTEOGENESIS THROUGH THE INVOVLVEMENT OF Gs-COUPLED RECEPTOR SIGNALS 158
The GABAA-BZR Complex as Target for the Development of Anxiolytic Drugs. 157
Potential biomarkers and novel pharmacological targets in protein aggregation-related neurodegenerative diseases 157
Development of ligands at gamma-aminobutyrric acid type A (GABA(A)) receptor subtype as new agents for pain relief 155
Frontal Affinity Chromatography-Mass Spectrometry Useful for Characterization of New Ligands for GPR17 Receptor 155
Human gingival mesenchymal stem cell trophism is modulated by inflammatory microenvironment: effects of ribes nigrum bud extract 155
Modulation of A1 and A2B adenosine receptor activity: a new strategy to sensitise glioblastoma stem cells to chemotherapy. 154
Agonist-induced desensitisation/resensitisation of human GPR17: a functional cross talk between purinergic and cysteinyl-leukotriene ligands 152
Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas 152
The mesenchymal stem cell differentiation to osteoblasts is potentiate by the allosteric modulation of A2B adenosine receptors. 152
Regular exercise delays microvascular endothelial dysfunction by regulating antioxidant capacity and cellular metabolism 152
Exploring the Role of Lipid-Binding Proteins and Oxidative Stress in Neurodegenerative Disorders: A Focus on the Neuroprotective Effects of Nutraceutical Supplementation and Physical Exercise 150
ROLE OF ADENOSINE RECEPTORS IN SURVIVAL AND DIFFERENTIATION OF GLIOBLASTOMA STEM CELLS 150
Aerobic Exercise and Healthy Nutrition as Neuroprotective Agents for Brain Health in Patients with Parkinson's Disease: A Critical Review of the Literature 150
Trazodone regulates neurotrophic/growth factors, mitogen-activated protein kinases and lactate release in human primary astrocytes 148
Regulation of Erythropoietin Receptor Activity in Endothelial Cells by Different Erythropoietin (EPO) Derivatives: An in Vitro Study. 147
Phenotypic changes, signaling pathway, and functional correlates of GPR17-expressing neural precursor cells during oligodendrocyte differentiation 146
Metabolic and Molecular Mechanisms of Diet and Physical Exercise in the Management of Polycystic Ovarian Syndrome 145
Oxysterols act as promiscuous ligands of class-A GPCRs: In silico molecular modeling and in vitro validation. 145
Discovery of MDM2-p53 and MDM4-p53 protein-protein interactions small molecule dual inhibitors 144
Oxidative Stress-Related Signaling Pathways Predict Oocytes’ Fertilization In Vitro and Embryo Quality 144
STUDIO CLINICO E NEUROBIOLOGICO IN PAZIENTI AFFETTI DA GIOCO D’AZZARDO PATOLOGICO 144
3-Aryl-1,2,4-triazino-4,3-abenzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists 144
Totale 19.821
Categoria #
all - tutte 78.174
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 78.174


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021248 0 0 0 0 0 0 0 0 0 0 61 187
2021/20221.805 40 112 62 83 324 247 73 95 78 65 101 525
2022/20232.739 322 353 187 245 343 330 21 185 525 27 145 56
2023/20241.958 160 152 239 126 262 313 100 74 41 70 114 307
2024/20255.838 64 221 99 349 494 582 482 328 698 776 650 1.095
2025/20267.600 433 1.058 1.029 605 778 627 1.416 359 464 664 167 0
Totale 29.170