DANIELE, SIMONA
 Distribuzione geografica
Continente #
NA - Nord America 16.178
AS - Asia 7.037
EU - Europa 6.616
SA - Sud America 949
Continente sconosciuto - Info sul continente non disponibili 608
AF - Africa 418
OC - Oceania 32
Totale 31.838
Nazione #
US - Stati Uniti d'America 15.676
IT - Italia 2.907
SG - Singapore 2.180
CN - Cina 1.944
HK - Hong Kong 1.079
VN - Vietnam 824
BR - Brasile 764
SE - Svezia 742
DE - Germania 729
BG - Bulgaria 402
CA - Canada 344
GB - Regno Unito 338
FR - Francia 322
FI - Finlandia 271
AT - Austria 220
RU - Federazione Russa 209
TR - Turchia 201
JP - Giappone 150
IN - India 136
KR - Corea 118
SN - Senegal 111
NG - Nigeria 101
UA - Ucraina 91
MX - Messico 76
CI - Costa d'Avorio 72
CH - Svizzera 64
NL - Olanda 59
PL - Polonia 54
AR - Argentina 51
IQ - Iraq 50
BD - Bangladesh 47
BE - Belgio 42
ES - Italia 41
PK - Pakistan 41
ZA - Sudafrica 39
ID - Indonesia 37
CO - Colombia 36
AU - Australia 28
UZ - Uzbekistan 26
GR - Grecia 25
IR - Iran 24
SA - Arabia Saudita 24
EC - Ecuador 23
MY - Malesia 23
EG - Egitto 22
JM - Giamaica 22
MA - Marocco 22
VE - Venezuela 20
AE - Emirati Arabi Uniti 18
PH - Filippine 18
UY - Uruguay 17
CL - Cile 16
JO - Giordania 15
LT - Lituania 14
IE - Irlanda 13
KE - Kenya 12
RO - Romania 12
CZ - Repubblica Ceca 11
AZ - Azerbaigian 10
CR - Costa Rica 10
GT - Guatemala 10
IL - Israele 10
NP - Nepal 9
PE - Perù 9
TW - Taiwan 9
HN - Honduras 8
TN - Tunisia 8
PT - Portogallo 7
PY - Paraguay 7
AL - Albania 6
BB - Barbados 6
DZ - Algeria 6
HU - Ungheria 6
NI - Nicaragua 6
BO - Bolivia 5
GE - Georgia 5
KZ - Kazakistan 5
MD - Moldavia 5
TT - Trinidad e Tobago 5
BF - Burkina Faso 4
BH - Bahrain 4
DK - Danimarca 4
DO - Repubblica Dominicana 4
LA - Repubblica Popolare Democratica del Laos 4
NZ - Nuova Zelanda 4
SV - El Salvador 4
BJ - Benin 3
BN - Brunei Darussalam 3
EE - Estonia 3
HR - Croazia 3
KG - Kirghizistan 3
LB - Libano 3
MK - Macedonia 3
OM - Oman 3
PS - Palestinian Territory 3
SI - Slovenia 3
A1 - Anonimo 2
BA - Bosnia-Erzegovina 2
BY - Bielorussia 2
CG - Congo 2
Totale 31.191
Città #
Ashburn 1.724
Serra 1.176
Singapore 1.147
Dallas 1.087
Hong Kong 1.050
Houston 1.040
Woodbridge 1.018
San Jose 900
Ann Arbor 857
Fairfield 833
Chandler 726
Santa Clara 629
Shanghai 402
Sofia 399
Beijing 396
Seattle 386
Council Bluffs 375
New York 334
Milan 299
Wilmington 298
Cambridge 294
Boardman 276
Ho Chi Minh City 240
Los Angeles 233
Ottawa 229
Princeton 207
Vienna 195
Hefei 188
Hanoi 158
Chicago 153
Lawrence 149
Lauterbourg 144
Medford 139
Tokyo 134
Pisa 133
Frankfurt am Main 127
Des Moines 116
Dakar 111
Florence 109
Helsinki 109
Nanjing 108
Seoul 103
London 102
Lagos 98
Buffalo 97
Munich 93
Dearborn 92
Istanbul 91
Jacksonville 91
Izmir 77
Redondo Beach 76
Abidjan 72
Rome 71
Lucca 67
São Paulo 61
Columbus 59
Livorno 59
Dong Ket 57
Atlanta 48
Lancaster 48
Phoenix 48
The Dalles 47
Washington 44
Bremen 43
Nanchang 42
Toronto 42
Brussels 41
Turku 41
Da Nang 40
Guangzhou 40
Rho 40
Warsaw 40
Redwood City 39
Ogden 38
Alessandria 37
Orem 37
Boulder 36
Zurich 36
Nuremberg 35
San Diego 35
San Francisco 32
Kunming 31
Montreal 31
Falls Church 29
Fuzhou 29
Kent 29
Haiphong 26
Bologna 25
Naples 25
Shenyang 25
Brooklyn 24
Paris 24
Changsha 23
Denver 23
Memphis 21
Tianjin 21
Hebei 20
Jiaxing 20
Marseille 20
Mexico City 20
Totale 21.389
Nome #
Platelet uptake of GABA and glutamate in patients with bipolar disorder. 417
Trazodone treatment protects neuronal-like cells from inflammatory insult by inhibiting NF-κB, p38 and JNK 417
METODO PER LA DIAGNOSI DI MALATTIE NEURODEGENERATIVE 348
G PROTEIN-COUPLED RECEPTOR DESENSITISATION REGULATES STEM CELL DIFFERENTIATION 344
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS INHIBITORS OF PDK1 (US Patent App. 15/735,468, 2018) 329
α-Synuclein Aggregates with β-Amyloid or Tau in Human Red Blood Cells: Correlation with Antioxidant Capability and Physical Exercise in Human Healthy Subjects 325
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 309
2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE AS DUAL INHIBITORS OF PDK1/AURA 307
Antioxidant Capability and Physical Exercise in Neurobiology: A Focus in Neurodegeneration 295
Studio sui trasportatori di GABA e glutammato nelle piastrine di soggetti con disturbo bipolare 285
Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma 282
Palmitoylethanolamide Counteracts Enteric Inflammation and Bowel Motor Dysfunctions in a Mouse Model of Alzheimer’s Disease 280
α-Synuclein Aggregated with Tau and β-Amyloid in Human Platelets from Healthy Subjects: Correlation with Physical Exercise 280
Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas 277
New insights into the anticancer activity of carnosol: P53 reactivation in the U87MG human glioblastoma cell line 272
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells 264
A2A adenosine receptor binding parameters in platelets from patients affected by pathological gambling 254
An in vitro comparative study of the antioxidant activity and SIRT1 modulation of natural compounds 254
Apolipoprotein E ε4 triggers neurotoxicity via cholesterol accumulation, acetylcholine dyshomeostasis, and PKCε mislocalization in cholinergic neuronal cells 250
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 250
Effect of Ribes nigrum bud extract on human gingival mesenchymal stem cell cytokine release: a role on regenerative processes 248
An antibody-free strategy for screening putative HDM2 inhibitors using crude bacterial lysates expressing GST-HDM2 recombinant protein 246
Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells 243
α-Synuclein Heterocomplexes with β-Amyloid Are Increased in Red Blood Cells of Parkinson's Disease Patients and Correlate with Disease Severity 243
Allosteric modulators of human A2B adenosine receptor. 242
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 242
Osteogenesis Is Improved by Low Tumor Necrosis Factor Alpha Concentration through the Modulation of Gs-Coupled Receptor Signals 242
Physical Exercise Improves Total Antioxidant Capacity and Gene Expression in Rat Hippocampal Tissue 241
Design, synthesis and biological evaluation of new H2S-releasing rivastigmine derivatives as neuroprotective molecules 238
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 236
Memantine prodrug as a new agent for alzheimer’s disease 233
Protective effect of high-dose montelukast on salbutamol-induced homologous desensitisation in airway smooth muscle. 231
A mixed-valence diruthenium(ii,iii) complex endowed with high stability: from experimental evidence to theoretical interpretation 229
α-Synuclein Heteromers in Red Blood Cells of Alzheimer's Disease and Lewy Body Dementia Patients 229
Carnosol controls the human glioblastoma stemness features through the epithelial-mesenchymal transition modulation and the induction of cancer stem cell apoptosis 224
Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts 223
Prodromal Intestinal Events in Alzheimer's Disease (AD): Colonic Dysmotility and Inflammation Are Associated with Enteric AD-Related Protein Deposition 223
New 3-, 8-disubstituted pyrazolo[5,1-c][1,2,4]benzotriazines useful for studying the interaction with the HBp-3 area (hydrogen bond point area) in the benzodiazepine site on the γ-aminobutyric acid type A (GABAA) receptor 216
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: A Novel Template for the Design of Highly Selective A(2B) Adenosine Receptor Antagonists. 214
Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death 212
Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease 211
The ubiquitin ligase Mdm2 controls oligodendrocyte maturation by intertwining mTOR with G protein-coupled receptor kinase 2 in the regulation of GPR17 receptor desensitization 210
Effects of long-term vegan diet on breath composition 210
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A(2B) adenosine receptor antagonists 205
Epigenetic Modifications of the α-Synuclein Gene and Relative Protein Content Are Affected by Ageing and Physical Exercise in Blood from Healthy Subjects 205
Endometrial dysbiosis is related to inflammatory factors in women with repeated implantation failure: a pilot study 203
Novel fluorescent triazinobenzimidazole derivatives as probes for labelling human A1 and A2B adenosine receptor subtypes 201
Apolipoprotein E Polymorphism and Oxidative Stress in Human Peripheral Blood Cells: Can Physical Activity Reactivate the Proteasome System through Epigenetic Mechanisms? 200
What Does the Brain Have to Keep Working at Its Best? Resilience Mechanisms Such as Antioxidants and Brain/Cognitive Reserve for Counteracting Alzheimer's Disease Degeneration 199
Human glioblastoma multiforme: p53 reactivation by a novel MDM2 inhibitor 199
Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: The use of natural compounds as modulatory agents 199
3-(Fur-2-yl)-10-(2-Phenylethyl)-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one, a Novel Adenosine Receptor Antagonist with (2A)-Mediated Neuroprotective EffeCTS 198
Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators. 197
Sex Differences in Blood Accumulation of Neurodegenerative-Related Proteins and Antioxidant Responses to Regular Physical Exercise 194
The A2B adenosine receptor modulates the epithelial- mesenchymal transition through the balance of cAMP/PKA and MAPK/ERK pathway activation in human epithelial lung cells 194
A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer 194
Adenosine receptors: what we know and what we are learning 192
Further studies on pyrazolo[1',5':1,6]pyrimido[4,5-d]pyridazin-4(3H)-ones as potent and selective human A1 adenosine receptor antagonists. 192
Modulation of A2B adenosine receptor by 1-benzyl-3-ketoindole derivatives 192
Discovery of the First-in-Class Dual TSPO/Carbonic Anhydrase Modulators with Promising Neurotrophic Activity 191
New Insight into the Central Benzodiazepine Receptor-Ligand Interactions: Design, Synthesis, Biological Evaluation, and Molecular Modeling of 3-Substituted 6-Phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and Related Compounds 190
Human Neural Stem Cell Aging Is Counteracted by α-Glycerylphosphorylethanolamine 189
Impact of ApoE Polymorphism and Physical Activity on Plasma Antioxidant Capability and Erythrocyte Membranes 188
The oral reversibly-binding antiplatelet agent, Ticagrelor, acts as an antagonist at the P2Y-like receptor GPR17 187
Does GRK-β arrestin machinery work as a "switch on" for GPR17-mediated activation of intracellular signaling pathways? 187
Novel N(2)-Substituted Pyrazolo[3,4-d]pyrimidine Adenosine A(3) Receptor Antagonists: Inhibition of A(3)-Mediated Human Glioblastoma Cell Proliferation (dagger) 186
Modulation of A2B Adenosine Receptor by 1-Benzyl-3-ketoindole Derivatives 186
A1 AND A2B ADENOSINE RECEPTORS REGULATE GLIOBLASTOMA STEM CELL DIFFERENTIATION/SURVIVAL AND SENSITIZE CELLS TO CHEMOTHERAPY 185
Long lasting MDM2/Translocator protein modulator: a new strategy for irreversible apoptosis of human glioblastoma cells 184
A specific combination of nutraceutical Ingredients exerts cytoprotective effects in human cholinergic neurons 181
Allosteric modulation of A2B adenosine receptors potentiate the effects of orthosteric receptor agonists to promote mesenchymal stem cell differentiation to osteoblasts. 179
A rapid and efficient immunoenzymatic assay to detect receptor protein interactions: g protein-coupled receptors. 177
High Levels of β-Amyloid, Tau, and Phospho-Tau in Red Blood Cells as Biomarkers of Neuropathology in Senescence-Accelerated Mouse 176
KEEP A WATCHFUL EYE ON CYRCADIAN RHYTHM AND BRAIN WELLNESS 175
TUMOR NECROSIS FACTOR ALPHA TRIGGERS OSTEOGENESIS THROUGH THE INVOVLVEMENT OF Gs-COUPLED RECEPTOR SIGNALS 175
Translocator protein (TSPO) and identification of new molecular diagnosis tools 174
Agonist-Induced Desensitization/Resensitization of Human G Protein-Coupled Receptor 17: A Functional Cross-Talk between Purinergic and Cysteinyl-Leukotriene Ligands 174
Compounds with a benzo [a]carbazole structure for use in the prevention and/or treatment of infectious diseases 170
Exploring Epithelial-Mesenchymal Transition Signals in Endometriosis Diagnosis and In Vitro Fertilization Outcomes 170
A promiscuous recognition mechanism between GPR17 and SDF-1: Molecular insights 169
Modulation of PAR(1) signaling by benzimidazole compounds 168
Regular exercise delays microvascular endothelial dysfunction by regulating antioxidant capacity and cellular metabolism 168
The GABAA-BZR Complex as Target for the Development of Anxiolytic Drugs. 166
The mesenchymal stem cell differentiation to osteoblasts is potentiate by the allosteric modulation of A2B adenosine receptors. 166
Potential biomarkers and novel pharmacological targets in protein aggregation-related neurodegenerative diseases 165
Human gingival mesenchymal stem cell trophism is modulated by inflammatory microenvironment: effects of ribes nigrum bud extract 165
ROLE OF ADENOSINE RECEPTORS IN SURVIVAL AND DIFFERENTIATION OF GLIOBLASTOMA STEM CELLS 164
Role of Adenosine Receptors in survival and differentiation of glioblastoma stem cells. 163
Frontal Affinity Chromatography-Mass Spectrometry Useful for Characterization of New Ligands for GPR17 Receptor 162
Regulation of Erythropoietin Receptor Activity in Endothelial Cells by Different Erythropoietin (EPO) Derivatives: An in Vitro Study. 161
Development of ligands at gamma-aminobutyrric acid type A (GABA(A)) receptor subtype as new agents for pain relief 160
Modulation of A1 and A2B adenosine receptor activity: a new strategy to sensitise glioblastoma stem cells to chemotherapy. 160
Trazodone regulates neurotrophic/growth factors, mitogen-activated protein kinases and lactate release in human primary astrocytes 160
3-Aryl-1,2,4-triazino-4,3-abenzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists 159
Exploring the Role of Lipid-Binding Proteins and Oxidative Stress in Neurodegenerative Disorders: A Focus on the Neuroprotective Effects of Nutraceutical Supplementation and Physical Exercise 158
Agonist-induced desensitisation/resensitisation of human GPR17: a functional cross talk between purinergic and cysteinyl-leukotriene ligands 158
Metabolic and Molecular Mechanisms of Diet and Physical Exercise in the Management of Polycystic Ovarian Syndrome 157
Aerobic Exercise and Healthy Nutrition as Neuroprotective Agents for Brain Health in Patients with Parkinson's Disease: A Critical Review of the Literature 157
Oxidative Stress-Related Signaling Pathways Predict Oocytes’ Fertilization In Vitro and Embryo Quality 156
STUDIO CLINICO E NEUROBIOLOGICO IN PAZIENTI AFFETTI DA GIOCO D’AZZARDO PATOLOGICO 155
Totale 21.510
Categoria #
all - tutte 87.543
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 87.543


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.653 0 0 62 83 324 247 73 95 78 65 101 525
2022/20232.739 322 353 187 245 343 330 21 185 525 27 145 56
2023/20241.958 160 152 239 126 262 313 100 74 41 70 114 307
2024/20255.838 64 221 99 349 494 582 482 328 698 776 650 1.095
2025/20267.982 433 1.058 1.029 605 778 627 1.416 359 464 664 335 214
2026/20272.286 273 988 1.025 0 0 0 0 0 0 0 0 0
Totale 31.838