DA SETTIMO PASSETTI, FEDERICO
 Distribuzione geografica
Continente #
NA - Nord America 20.349
EU - Europa 10.025
AS - Asia 4.444
AF - Africa 354
SA - Sud America 151
OC - Oceania 67
Continente sconosciuto - Info sul continente non disponibili 2
Totale 35.392
Nazione #
US - Stati Uniti d'America 19.764
IT - Italia 4.162
CN - Cina 2.084
SE - Svezia 1.913
DE - Germania 1.057
SG - Singapore 898
BG - Bulgaria 841
TR - Turchia 652
CA - Canada 575
GB - Regno Unito 433
VN - Vietnam 383
FI - Finlandia 318
AT - Austria 316
UA - Ucraina 310
RU - Federazione Russa 211
CI - Costa d'Avorio 159
IN - India 153
FR - Francia 137
BR - Brasile 131
HK - Hong Kong 129
CH - Svizzera 104
NG - Nigeria 99
BE - Belgio 71
JP - Giappone 67
AU - Australia 65
SN - Senegal 64
NL - Olanda 35
CZ - Repubblica Ceca 21
PL - Polonia 21
GR - Grecia 14
KR - Corea 14
EG - Egitto 12
IR - Iran 11
BJ - Benin 10
PK - Pakistan 10
DK - Danimarca 9
ES - Italia 9
LT - Lituania 8
EC - Ecuador 7
ID - Indonesia 6
MX - Messico 6
RO - Romania 6
HU - Ungheria 5
IE - Irlanda 5
PT - Portogallo 5
AR - Argentina 4
AZ - Azerbaigian 4
BD - Bangladesh 4
IL - Israele 4
IQ - Iraq 4
JO - Giordania 4
SA - Arabia Saudita 4
BF - Burkina Faso 3
CL - Cile 3
HR - Croazia 3
TW - Taiwan 3
ZA - Sudafrica 3
EE - Estonia 2
EU - Europa 2
GA - Gabon 2
JM - Giamaica 2
NZ - Nuova Zelanda 2
SI - Slovenia 2
VE - Venezuela 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
BA - Bosnia-Erzegovina 1
BN - Brunei Darussalam 1
CO - Colombia 1
CY - Cipro 1
DZ - Algeria 1
GE - Georgia 1
GL - Groenlandia 1
KZ - Kazakistan 1
LI - Liechtenstein 1
LK - Sri Lanka 1
MC - Monaco 1
MD - Moldavia 1
ME - Montenegro 1
MY - Malesia 1
OM - Oman 1
PA - Panama 1
PE - Perù 1
PH - Filippine 1
PS - Palestinian Territory 1
PY - Paraguay 1
RS - Serbia 1
TN - Tunisia 1
UY - Uruguay 1
Totale 35.392
Città #
Woodbridge 2.893
Ann Arbor 2.320
Houston 2.055
Serra 1.614
Chandler 1.591
Fairfield 1.559
Santa Clara 1.245
Ashburn 1.006
Sofia 841
Milan 744
Seattle 621
Wilmington 620
Beijing 585
Ottawa 539
New York 511
Izmir 495
Cambridge 475
Singapore 445
Jacksonville 413
Boardman 396
Princeton 384
Lawrence 334
Nanjing 295
Shanghai 288
Medford 276
Vienna 272
Des Moines 215
Dong Ket 209
London 186
Rho 180
Frankfurt am Main 168
Abidjan 159
Dearborn 155
Istanbul 144
Hong Kong 122
Lagos 99
Nanchang 96
Rome 95
Bern 94
Bremen 94
Pisa 88
San Diego 86
Los Angeles 82
Redwood City 76
Florence 73
Brussels 71
Ogden 70
Boulder 69
Chicago 68
Jüchen 68
Düsseldorf 67
Dakar 64
Kunming 63
Shenyang 62
Hebei 59
Pune 59
Falls Church 52
Fuzhou 47
Nürnberg 46
Changsha 45
Sydney 43
Hefei 42
Tianjin 38
Auburn Hills 36
Norwalk 35
Lucca 33
Guangzhou 31
Washington 31
Jiaxing 29
Livorno 29
Quanzhou 29
Hangzhou 28
San Jose 28
Marseille 27
Alessandria 25
Helsinki 25
Toronto 24
Dallas 22
Pistoia 22
Lancaster 21
Orange 21
Pessac 21
San Francisco 21
Cascina 18
Jinan 18
Warsaw 18
Phoenix 15
Vicopisano 15
Santa Margherita Ligure 14
São Paulo 14
Talence 14
Wuhan 14
Aversa 13
Indiana 13
Xiamen 12
Amsterdam 11
Citta 11
Kent 11
Lappeenranta 11
Massa 11
Totale 27.042
Nome #
1,2-Benzisothiazole Derivatives Bearing 4-, 5-, or 6-Alkyl/arylcarboxamide Moieties Inhibit Carbonic Anhydrase Isoform IX (CAIX) and Cell Proliferation under Hypoxic Conditions 324
TSPO ligand residence time influences human glioblastoma multiforme cell death/life balance 262
Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma 227
Benzofuroxane Derivatives as Multi Effective Agents for the Treatment of Cardiovascular Diabetic Complications. Synthesis, Functional Evaluation, and Molecular Modeling Studies 211
N, N-Dialkyl-2-phenylindol-3-ylglyoxylamides.A new class of potent and selective ligands at the Peripheral benzodiazepine receptor 210
A new class of tyrosine kinase inhibitors, “pyrazolo[3,4-d]pyrimidinic”compounds, has antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer 198
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells 196
Exploiting the Pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors, 191
Allosteric modulators of human A2B adenosine receptor. 188
Iminothioethers as Hydrogen Sulfide Donors: From the Gasotransmitter Release to the Vascular Effects 188
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: a New Class of Selective Aldose Reductase Inhibitors 185
Soyasaponins from Zolfino bean as aldose reductase differential inhibitors 180
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: A New Class of Selective Aldose Reductase Inhibitors 177
3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: A New Class of Selective A1 Adenosine Receptor Antagonists 176
Anti-inflammatory effect of a novel adenosine deaminase inhibitor in experimental colitis 175
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 175
The Alpha Keto Amide Moiety as a Privileged Motif in Medicinal Chemistry: Current Insights and Emerging Opportunities 174
3-aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: Tricyclic heteroaromatic derivatives as a new class of benzodiazepine receptor ligands 173
CLM29, a multi-target pyrazolopyrimidine derivative, has anti-neoplastic activity in medullary thyroid cancer in vitro and in vivo 172
TSPO PIGA ligands promote neurosteroidogenesis and human astrocyte well-being 171
TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy 171
Identification of Anxiolytic/Nonsedative Agents among Indol-3-ylglyoxylamides Acting as Functionally Selective Agonists at the γ-Aminobutyric Acid-A (GABAA) α2 Benzodiazepine Receptor 169
Acid Derivatives of Pyrazolo[1,5-a]pyrimidine as Aldose Reductase Differential Inhibitors 167
G-Protein-Coupled Receptor Kinase 2 (GRK2) Inhibitors: Current Trends and Future Perspectives. 166
N '-phenylindol-3-ylglyoxylohydrazide derivatives: Synthesis, structure-activity relationships, molecular modeling studies, and pharmacological action on brain benzodiazepine receptors 165
p53 Functional Inhibitors Behaving Like Pifithrin-β Counteract the Alzheimer Peptide Non-β-amyloid Component Effects in Human SH-SY5Y Cells. 165
Antineoplastic activity of the multitarget tyrosine kinase inhibitors CLM3 and CLM94 in medullary thyroid cancer in vitro 165
CLM3, a multitarget tyrosine kinase inhibitor with antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo 163
Novel pyrazolopyrimidine derivatives as tyrosine kinase inhibitors with antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer. 159
Allosteric Modulators for Adenosine Receptors: An Alternative to the Orthosteric Ligands 158
Arylthioamides as H2S Donors:l-Cysteine-Activated Releasing Properties and Vascular Effects in Vitro and in Vivo 158
Drug-target Residence Time: a key parameter in glial responses to TSPO ligands 157
Refinement of Structure-activity Relationships of the Triazinobenzimidazole A1AR Antagonists 154
Synthesis of a Novel Purine-Containing Heterocyclic Ring System: 8,10-Dimethylindolo[2',3':5,6][1,2,4]triazino[4,3-f]purine-9,11(8H,10H,13H)dione 154
TSPO-ligands prevent oxidative damage and inflammatory response in C6 glioma cells by neurosteroid synthesis 154
Geometrically Constrained Analogues N-Benzylindolylglyoxylylamides: [1,2,4]Triazino[4,3-a]benzimidazol-4(10H)-one Derivatives as Potential New Ligands at the Benzodiazepine Receptor. 152
Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity 151
Structural requirements to obtain highly potent and selective 18 kDa Translocator Protein (TSPO) ligands 151
Residence Time (RT), a new parameter to predict neurosteroidogenic efficacy of Translocator Protein (TSPO) ligands: N,N-dialkyl-2-arylindol-3-ylglyoxylamides, a case study 151
5-Amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a Versatile Scaffold to Obtain Potent and Selective A3 Adenosine Receptor Antagonists 149
Synthesis of novel 1-aryl[1]benzoxepino[5,4-c]pyrazole and [1]benzoxepino[5,4-d]pyrimidine derivatives 148
3-(Fur-2-yl)-10-(2-Phenylethyl)-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one, a Novel Adenosine Receptor Antagonist with (2A)-Mediated Neuroprotective EffeCTS 148
Benzo[d]isothiazoles and Matrix Metalloproteinases. Searching for Novel and Selective Inhibitors of MMP9 147
Hydrogen Sulphide: Biopharmacological Roles in the Cardiovascular System and Pharmaceutical Perspectives. 147
The ra structure of tellurophene-2-carboxaldehyde by using the proton NMR spectrum in an oriented phase including carbon-13 and tellurium-125 satellites 146
FACILE SYNTHESIS OF 3-SUBSTITUTED[1,2,4]TRIAZINO[3,4-F]PURINE-4,6,8-TRIONE DERIVATIVES 146
2-(Benzimidazol-2-yl)quinoxalines: A Novel Class of selective Antagonists at Human A1 and A3 Adenosine Receptors Designed by 3D Database Searching 146
Identification of 5-arylidene-4-thiazolidinone derivatives endowed with dual activity as aldose reductase inhibitors and antioxidant agents for the treatment of diabetic complications 146
1-Substituted 2-(benzylamino)benzimidazole derivatives: compounds with H1-antihistaminic activity 145
11C-ER176, a radioligand for 18-kDa translocator protein, has adequate sensitivity to robustly image all three affinity genotypes in human brain 145
Recent Advances in the Development of Dual Topoisomerase I and II Inhibitors as Anticancer Drugs 145
Modulation of A2B Adenosine Receptor by 1-Benzyl-3-ketoindole Derivatives 144
Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII 144
Long Residence Time at the Neurosteroidogenic 18 kDa Translocator Protein Characterizes the Anxiolytic Ligand XBD173 144
“Synthesis and antiproliferative evaluation of new substituted Benzothiopyrano[4,3-c] condensed ring systems” 143
Synthesis of Purinobenzodiazepine and Purinobenzotriazocine derivatives, two new heterocyclic ring systems. 143
Pursuing Aldose Reductase Inhibitors through in Situ Cross-Docking and Similarity-Based Virtual Screening 143
Targeting the 18-kDa translocator protein: Recent perspectives for neuroprotection 142
Benzothiopyranoindole-Based Antiproliferative Agents: Synthesis, Cytotoxicity, Nucleic Acids Interaction, and Topoisomerases Inhibition Properties. 141
Modulation of A2B adenosine receptor by 1-benzyl-3-ketoindole derivatives 141
Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators. 140
Novel, Highly Potent Aldose Reductase Inhibitors:Cyano(2-oxo-2,3-dihydroindol-3-yl)acetic Acid Derivatives 139
Functional Studies in the Year of Pulses: the case of Zolfino landraces (Phaesolus vulgaris L.) 139
Medicinal chemistry of indolylglyoxylamide TSPO high affinity ligands with anxiolytic-like effects 138
Long lasting inhibition of Mdm2-p53 interaction potentiates mesenchymal stem cell differentiation into osteoblasts 138
An approach to novel fused triazole or tetrazole derivatives starting from Benzimidazo[1,2-a]quinazoline-5(7H)-one and 5,7-Dihydro-5-oxopyrido[3',2':5,6]pyrimido[1,2-a]benzimidazole 136
A New Approach to Control the Enigmatic Activity of Aldose Reductase 136
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of non-camptothecin Topoisomerase I (Top1) inhibitors 136
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors 136
Novel N(2)-Substituted Pyrazolo[3,4-d]pyrimidine Adenosine A(3) Receptor Antagonists: Inhibition of A(3)-Mediated Human Glioblastoma Cell Proliferation (dagger) 135
Synthesis of Pyrimido[1,2-a]benzimidazol-4(10H)-one Derivatives and Evaluation of their Interactions with DNA 134
Novel Potent and Selective Human Adenosine A3 Receptor Antagonists Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis and Biological Evaluation 134
An update into the medicinal chemistry of translocator protein (TSPO) ligands 134
"2-Phenyl[1,2,3]triazole[1,2-a][1,2,4]triazin-1,5(6H)-dione: a derivative of a new tricyclic heteroaromatic system with high affinity at the benzodiazepine receptor" 133
Studies in search for selective ligands for GABAA/BzR receptor subtypes: synthesis and biological evaluation of 4'-modified N-(benzyl)indol-3-ylglyoxylamides 132
Structure-Based Optimization of Tyrosine Kinase Inhibitor CLM3. Design, Synthesis, Functional Evaluation, and Molecular Modeling Studies. 132
The Anxiolytic Etifoxine Binds to TSPO Ro5-4864 Binding Site with Long Residence Time Showing a High Neurosteroidogenic Activity 132
A1 adenosine receptor antagonists, 3-aryl[1,2,4]triazino[4,3-a]benzimidazol-4-(10H)-ones (ATBIs) and N-alkyl and N-acyl-(7-substituted-2-phenylimidazo[1,2-a][1,3,5]triazin-4-yl)amines (ITAs): different recognition of bovine and human binding sites 131
Acetic acid aldose reductase inhibitors bearing a five-membered heterocyclic core with potent topical activity in a visual impairment rat model 131
SPECIFIC-INHIBITION OF BENZODIAZEPINE RECEPTOR-BINDING BY SOME N-(INDOL-3-YLGLYOXYLYL)AMINO ACID-DERIVATIVES - STEREOSELECTIVE INTERACTIONS 130
The blockade of adenosine deaminase ameliorates chronic experimental colitis through the recruitment of adenosine A2A and A3 receptors 130
Medicinal chemistry of indolylglyoxylamide GABAA/BzR high affinity ligands: identification of novel anxiolytic/non sedative agents 130
Spirohydantoin Derivatives of Thiopyrano[2,3-b]pyridin-4(4H)-one as Potent in Vitro and in Vivo Aldose Reductase Inhibitors 129
Translocator protein ligands as promising therapeutic tools for anxiety disorders 129
Synthesis of novel pyrido[3',2':5,6]thiopyrano[3,2-b]indol-5(6H)-ones and 6H-pyrido[3',2':5,6]thiopyrano[4,3-b]quinolines,two new heterocyclic systems. 128
Prediction Model on Optionally Substituted 5,6-Membered Fused Ring Systems Containing C and/or N Atoms as Antifungal Agents Against Candida albicans Developed by Data Mining 127
Synthesis and Biological Evaluation of 4-Phenylquinazoline-2-carboxamides Designed as a Novel Class of Potent Ligands of the Translocator Protein 127
Novel Pyrazolo[3,4-d]pyrimidine Derivatives as ATP-competitive Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase 126
CLM94, a novel cyclic amide with anti-VEGFR-2 and antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo 126
Receptor tyrosine kinase kit and gastrointestinal stromal tumours: an overview 126
Investigation of new 2-aryl substituted Benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors targeting vascular endothelial growth factor receptor 2 126
Synthesis of novel 1,4-dihydropyrido[3’,2’:5,6]thiopyrano[4,3-c]-pyrazoles and 5H-pyrido[3’,2’:5,6]thiopyrano[4,3-d]pyrimidines as potential antiproliferative agents 125
Adenosine deaminase in the modulation of immune system and its potential as a novel target for treatment of inflammatory disorders 125
Synthesis of New Heterocyclic Ring Systems via [1,3,5]Triazino[1,2-a]benzimidazole Derivatives 124
Translocator protein (tspo) ligand residence time: a new parameter to predict neurosteroidogenic efficacy for n,n-dialkyl-2-arylindol-3-ylglyoxylamides (PIGAs) 124
Derivatives of 4-Amino-6-hydroxy-2-mercaptopyrimidine as Novel, Potent, and Selective A3 Adenosine Receptor Antagonists 124
Characterization of a new fluorescent irreversible ligand to translocator protein (18 kDa) 123
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A(2B) adenosine receptor antagonists 123
Pyrazolo[3,4,-d]pyrimidine-4-one Derivatives as Novel and Potent Inhibitors of Adenosine Deaminase 122
H2S-RELEASING PROPERTIES OF NEW THIOAMIDE, IMINOTHIOETHER AND ISOTHIOCYANATE DERIVATIVES 122
Totale 15.238
Categoria #
all - tutte 93.543
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 93.543


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.615 0 0 0 0 0 475 551 347 452 305 402 83
2020/20212.882 606 142 160 85 281 112 97 263 272 231 156 477
2021/20224.047 100 333 155 250 673 552 120 203 144 131 234 1.152
2022/20235.403 675 817 372 540 602 693 60 397 907 30 245 65
2023/20243.696 424 364 419 224 495 722 190 108 64 92 186 408
2024/20253.404 73 407 114 690 1.195 925 0 0 0 0 0 0
Totale 36.105