CINECA IRIS Institutional Research Information System

LA MOTTA, CONCETTINA
 Distribuzione geografica
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Continente #
NA - Nord America 11.701
EU - Europa 6.330
AS - Asia 2.495
AF - Africa 203
SA - Sud America 30
OC - Oceania 26
Continente sconosciuto - Info sul continente non disponibili 1
Totale 20.786
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Nazione #
US - Stati Uniti d'America 11.404
IT - Italia 2.711
SE - Svezia 1.424
CN - Cina 974
SG - Singapore 532
DE - Germania 525
BG - Bulgaria 488
TR - Turchia 412
VN - Vietnam 301
CA - Canada 293
GB - Regno Unito 268
AT - Austria 246
FI - Finlandia 160
UA - Ucraina 145
IN - India 105
CI - Costa d'Avorio 96
FR - Francia 93
HK - Hong Kong 81
RU - Federazione Russa 70
NG - Nigeria 68
CH - Svizzera 57
BE - Belgio 39
PL - Polonia 26
AU - Australia 23
JP - Giappone 22
SN - Senegal 20
BR - Brasile 19
NL - Olanda 18
PK - Pakistan 13
GR - Grecia 12
CZ - Repubblica Ceca 10
DK - Danimarca 9
IR - Iran 9
EG - Egitto 8
ES - Italia 8
ID - Indonesia 7
IE - Irlanda 7
KR - Corea 6
EC - Ecuador 5
MA - Marocco 5
NO - Norvegia 5
TH - Thailandia 5
CO - Colombia 4
MX - Messico 4
SA - Arabia Saudita 4
UZ - Uzbekistan 4
BJ - Benin 3
NZ - Nuova Zelanda 3
AE - Emirati Arabi Uniti 2
AZ - Azerbaigian 2
CL - Cile 2
DZ - Algeria 2
IQ - Iraq 2
JO - Giordania 2
LT - Lituania 2
PH - Filippine 2
RS - Serbia 2
TW - Taiwan 2
AL - Albania 1
BD - Bangladesh 1
BN - Brunei Darussalam 1
EU - Europa 1
GE - Georgia 1
HR - Croazia 1
IL - Israele 1
KZ - Kazakistan 1
MY - Malesia 1
NP - Nepal 1
PT - Portogallo 1
RO - Romania 1
SK - Slovacchia (Repubblica Slovacca) 1
SY - Repubblica araba siriana 1
TN - Tunisia 1
Totale 20.786
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Città #
Woodbridge 1.634
Ann Arbor 1.361
Houston 1.208
Fairfield 1.065
Chandler 939
Serra 881
Ashburn 648
Milan 538
Sofia 488
Seattle 447
Wilmington 406
Beijing 356
Cambridge 356
Izmir 306
New York 304
Singapore 276
Ottawa 264
Boardman 257
Princeton 230
Jacksonville 209
Lawrence 192
Vienna 187
Dong Ket 168
Nanjing 163
Medford 158
London 129
Des Moines 116
Abidjan 96
Rome 96
Istanbul 94
Dearborn 89
Rho 85
Hong Kong 79
Lagos 68
Bremen 62
Florence 62
Frankfurt am Main 61
Redwood City 56
Boulder 51
San Diego 51
Bern 49
Chicago 48
Nanchang 47
Los Angeles 42
Brussels 39
Fuzhou 37
Jüchen 36
Kunming 35
Shenyang 35
Pisa 34
Hebei 32
Pune 32
Ogden 31
Falls Church 30
Shanghai 30
Düsseldorf 28
Marseille 28
Lucca 27
Warsaw 23
Santa Clara 22
Washington 22
Dallas 21
Hefei 21
Changsha 20
Dakar 20
Nürnberg 19
Auburn Hills 18
Norwalk 17
Quanzhou 17
Toronto 17
Tianjin 16
Cascina 15
Orange 15
Hangzhou 13
Jiaxing 13
Kent 13
Lancaster 12
San Francisco 12
Citta 11
Guangzhou 11
Jinan 11
Phoenix 11
Sydney 11
Cesa 10
Helsinki 9
Indiana 9
Livorno 9
Bologna 8
Melbourne 8
São Paulo 8
Talence 8
Tokyo 8
Viareggio 8
Wuhan 8
Mumbai 7
Parma 7
Pessac 7
Xiamen 7
Zhengzhou 7
Brno 6
Totale 15.411
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Nome #
Derivati isoindolici come attivatori di AMPK 375
1,2-Benzisothiazole Derivatives Bearing 4-, 5-, or 6-Alkyl/arylcarboxamide Moieties Inhibit Carbonic Anhydrase Isoform IX (CAIX) and Cell Proliferation under Hypoxic Conditions 319
Benzofuroxane Derivatives as Multi Effective Agents for the Treatment of Cardiovascular Diabetic Complications. Synthesis, Functional Evaluation, and Molecular Modeling Studies 204
A new class of tyrosine kinase inhibitors, “pyrazolo[3,4-d]pyrimidinic”compounds, has antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer 189
Preparation of isoindoline derivatives for use as AMPK activators 185
Exploiting the Pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors, 183
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: a New Class of Selective Aldose Reductase Inhibitors 180
Derivati benzofuranici come attivatori di AMPK 174
Soyasaponins from Zolfino bean as aldose reductase differential inhibitors 172
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: A New Class of Selective Aldose Reductase Inhibitors 171
3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: A New Class of Selective A1 Adenosine Receptor Antagonists 170
3-aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: Tricyclic heteroaromatic derivatives as a new class of benzodiazepine receptor ligands 169
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 168
CLM29, a multi-target pyrazolopyrimidine derivative, has anti-neoplastic activity in medullary thyroid cancer in vitro and in vivo 166
Acid Derivatives of Pyrazolo[1,5-a]pyrimidine as Aldose Reductase Differential Inhibitors 163
Identification of Anxiolytic/Nonsedative Agents among Indol-3-ylglyoxylamides Acting as Functionally Selective Agonists at the γ-Aminobutyric Acid-A (GABAA) α2 Benzodiazepine Receptor 162
Antineoplastic activity of the multitarget tyrosine kinase inhibitors CLM3 and CLM94 in medullary thyroid cancer in vitro 160
CLM3, a multitarget tyrosine kinase inhibitor with antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo 158
How Reliable Are Current Docking Approaches for Structure-based Drug Design? Lessons from Aldose Reductase 155
Novel pyrazolopyrimidine derivatives as tyrosine kinase inhibitors with antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer. 154
N-(aroyl)-N-(arylmethyloxy)-α-alanines: selective inhibitors of aldose reductase 152
Synthesis of a Novel Purine-Containing Heterocyclic Ring System: 8,10-Dimethylindolo[2',3':5,6][1,2,4]triazino[4,3-f]purine-9,11(8H,10H,13H)dione 149
Refinement of Structure-activity Relationships of the Triazinobenzimidazole A1AR Antagonists 148
Evidence for a Novel Binding Site Conformer of Aldose Reductase in Ligand-Bound State 148
Synthesis of novel 1-aryl[1]benzoxepino[5,4-c]pyrazole and [1]benzoxepino[5,4-d]pyrimidine derivatives 145
5-Amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a Versatile Scaffold to Obtain Potent and Selective A3 Adenosine Receptor Antagonists 144
Vandetanib has antineoplastic activity in anaplastic thyroid cancer, in vitro and in vivo 144
Hemp (Cannabis sativa L.) flour: an active ingredient for the formulation of nutritious, flavorful and affordable foods. 144
2-(Benzimidazol-2-yl)quinoxalines: A Novel Class of selective Antagonists at Human A1 and A3 Adenosine Receptors Designed by 3D Database Searching 142
Identification of 5-arylidene-4-thiazolidinone derivatives endowed with dual activity as aldose reductase inhibitors and antioxidant agents for the treatment of diabetic complications 142
Benzo[d]isothiazoles and Matrix Metalloproteinases. Searching for Novel and Selective Inhibitors of MMP9 141
Recent Advances in the Development of Dual Topoisomerase I and II Inhibitors as Anticancer Drugs 140
“Synthesis and antiproliferative evaluation of new substituted Benzothiopyrano[4,3-c] condensed ring systems” 138
Synthesis of Purinobenzodiazepine and Purinobenzotriazocine derivatives, two new heterocyclic ring systems. 137
Allosteric Modulators for Adenosine Receptors: An Alternative to the Orthosteric Ligands 137
Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII 137
A Series of COX-2 Inhibitors Endowed with NO-Releasing Properties: Synthesis, Biological Evaluation, and Docking Analysis 136
Benzothiopyranoindole-Based Antiproliferative Agents: Synthesis, Cytotoxicity, Nucleic Acids Interaction, and Topoisomerases Inhibition Properties. 135
Novel, Highly Potent Aldose Reductase Inhibitors:Cyano(2-oxo-2,3-dihydroindol-3-yl)acetic Acid Derivatives 135
Functional Studies in the Year of Pulses: the case of Zolfino landraces (Phaesolus vulgaris L.) 134
A New Approach to Control the Enigmatic Activity of Aldose Reductase 132
Novel N(2)-Substituted Pyrazolo[3,4-d]pyrimidine Adenosine A(3) Receptor Antagonists: Inhibition of A(3)-Mediated Human Glioblastoma Cell Proliferation (dagger) 131
Medicinal chemistry of indolylglyoxylamide TSPO high affinity ligands with anxiolytic-like effects 131
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of non-camptothecin Topoisomerase I (Top1) inhibitors 129
Studies in search for selective ligands for GABAA/BzR receptor subtypes: synthesis and biological evaluation of 4'-modified N-(benzyl)indol-3-ylglyoxylamides 128
Novel Potent and Selective Human Adenosine A3 Receptor Antagonists Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis and Biological Evaluation 128
Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors 128
null 128
Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity 126
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 126
Lenvatinib exhibits antineoplastic activity in anaplastic thyroid cancer in vitro and in vivo 126
A1 adenosine receptor antagonists, 3-aryl[1,2,4]triazino[4,3-a]benzimidazol-4-(10H)-ones (ATBIs) and N-alkyl and N-acyl-(7-substituted-2-phenylimidazo[1,2-a][1,3,5]triazin-4-yl)amines (ITAs): different recognition of bovine and human binding sites 125
Structure-Based Optimization of Tyrosine Kinase Inhibitor CLM3. Design, Synthesis, Functional Evaluation, and Molecular Modeling Studies. 125
Synthesis of novel pyrido[3',2':5,6]thiopyrano[3,2-b]indol-5(6H)-ones and 6H-pyrido[3',2':5,6]thiopyrano[4,3-b]quinolines,two new heterocyclic systems. 124
The blockade of adenosine deaminase ameliorates chronic experimental colitis through the recruitment of adenosine A2A and A3 receptors 124
Acetic acid aldose reductase inhibitors bearing a five-membered heterocyclic core with potent topical activity in a visual impairment rat model 124
Effects of the new aldose reductase inhibitor benzofuroxane derivative bf-5m on high glucose induced prolongation of cardiac qt interval and increase of coronary perfusion pressure 124
Receptor tyrosine kinase kit and gastrointestinal stromal tumours: an overview 123
Medicinal chemistry of indolylglyoxylamide GABAA/BzR high affinity ligands: identification of novel anxiolytic/non sedative agents 123
Novel Pyrazolo[3,4-d]pyrimidine Derivatives as ATP-competitive Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase 122
Adenosine deaminase in the modulation of immune system and its potential as a novel target for treatment of inflammatory disorders 122
CLM94, a novel cyclic amide with anti-VEGFR-2 and antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo 122
Pursuing Aldose Reductase Inhibitors through in Situ Cross-Docking and Similarity-Based Virtual Screening 122
Synthesis and investigation of polyhydroxylated pyrrolidine derivatives as novel chemotypes showing dual activity as glucosidase and aldose reductase inhibitors 121
Synthesis of New Heterocyclic Ring Systems via [1,3,5]Triazino[1,2-a]benzimidazole Derivatives 120
Tertiary amides with a five-membered heteroaromatic ring as new probes for the translocator protein 118
Novel quinazolinone-based 2,4-thiazolidinedione-3-acetic acid derivatives as potent aldose reductase inhibitors 118
Investigation of new 2-aryl substituted Benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors targeting vascular endothelial growth factor receptor 2 118
Naphtho[1,2-d]isothiazole Acetic Acid Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors 116
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A(2B) adenosine receptor antagonists 116
Pyrazolo[3,4,-d]pyrimidine-4-one Derivatives as Novel and Potent Inhibitors of Adenosine Deaminase 115
Synthesis and biological activity of 1,4-dihydrobenzothiopyrano[4,3-c]pyrazole derivatives, novel pro-apoptotic mitochondrial targeted agents 115
Small Molecules Containing the Benzo[d]isotiazole Ring System as Novel ATP-Competitive Inhibitors of Epidermal Growth Factor Receptor protein Tyrosine Kinase 114
Microwave-assisted Suzuki Coupling in Aqueous Media: a Useful Tool for the Synthesis of 3-Arylindazole Derivatives 112
Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors 112
Non-nucleoside inhibitors of human adenosine kinase: synthesis, molecular modeling, and biological studies 111
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: A Novel Template for the Design of Highly Selective A(2B) Adenosine Receptor Antagonists. 111
Spirohydantoin Derivatives of Thiopyrano[2,3-b]pyridin-4(4H)-one as Potent in Vitro and in Vivo Aldose Reductase Inhibitors 110
Sampling protein motion and solvent effect during ligand binding. 110
Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands 110
Novel Aldose Reductase Acetic acid Inhibitors Bearing a Five Membered heterocyclic core 109
Quinazolinone-based rhodanine-3-acetic acids as potent aldose reductase inhibitors: Synthesis, functional evaluation and molecular modeling study 109
null 109
Synthesis and Biological Evaluation of Pyrido[1,2-d]pyrimidin-4-one Derivatives as Novel Aldose Reductase Inhibitors Exhibiting Antioxidant Activity 108
Computational Studies of Epidermal Growth Factor Receptor for Docking Reliability, Three-Dimensional Quantitative Structure-Activity Relationship Analysis, and Virtual Screening Studies 108
Lead Optimization of 2-Phenylindolylglyoxylyldipeptide Murine Double Minute (MDM)2/Translocator Protein (TSPO) Dual Inhibitors for the Treatment of Gliomas 108
AMPK Activators as Novel Drug Candidates for the Treatment of Inflammatory Bowel Diseases 108
ANTI-ISCHEMIC ACTIVITY OF AN ANTIOXIDANT ALDOSE REDUCTASE INHIBITOR ON DIABETIC AND NON-DIABETIC RAT HEARTS 107
Novel Irreversible Fluorescent Probes Targeting the 18 kDa Translocator Protein: Synthesis and Biological Characterization 107
CLM29 and CLM24, pyrazolopyrimidine derivatives, have antitumoral activity in vitro in anaplastic thyroid cancer, with or without BRAF mutation 106
A 2,3-diphenylpyrido[1,2-a] pyrimidin-4-one derivative inhibits specific angiogenic factors induced by TNF-α 106
Antiproliferative and proapoptotic activity of CLM3, a novel multiple tyrosine kinase inhibitor, alone and in combination with SN-38 on endothelial and cancer cells 105
Refinement of the Benzodiazepine Receptor Site Topology by Structure-Activity Relationships of New N-(Heteroarylmethyl)indol-3-ylglyoxylamides 104
Geometrically Constrained Derivatives of Indolylglyoxylamides as Ligands Binding the GABAA/BzR Complex. 104
INDOLE AMIDE DERIVATIVES: SYNTHESIS, STUCTURE-ACTIVITY RELATIONSHIPS AND MOLECULAR MODELLING STUDIES OF A NEW SERIES OF HISTAMINE H1-RECEPTOR ANTAGONISTS. 104
null 104
Derivatives of 4-Amino-6-hydroxy-2-mercaptopyrimidine as Novel, Potent, and Selective A3 Adenosine Receptor Antagonists 104
Dual Kit/Aur Inhibitors as Chemosensitizing Agents for the Treatment of Melanoma: Design, Synthesis, Docking Studies and Functional Investigation 104
Rational Design and Synthesis of Potent and Selective Adenosine Receptor Antagonists 103
Nuova tipologia di inibitori dell'enzima aldoso reduttasi 103
Totale 13.565
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Categoria #
all - tutte 55.740
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 55.740
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.167 0 0 0 0 277 317 356 249 383 243 268 74
2020/20211.972 338 101 84 76 159 87 138 183 173 162 98 373
2021/20222.579 61 171 117 205 448 315 63 133 114 69 174 709
2022/20233.392 471 572 256 303 376 433 67 230 466 21 151 46
2023/20242.302 288 258 279 180 327 430 87 47 32 66 69 239
2024/2025965 62 264 98 424 117 0 0 0 0 0 0 0
Totale 21.277