CINECA IRIS Institutional Research Information System

MACCHIA, MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 16.550
EU - Europa 8.323
AS - Asia 2.748
AF - Africa 187
OC - Oceania 30
SA - Sud America 28
Continente sconosciuto - Info sul continente non disponibili 7
Totale 27.873
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Nazione #
US - Stati Uniti d'America 16.084
IT - Italia 3.242
SE - Svezia 1.568
CN - Cina 1.239
DE - Germania 1.116
BG - Bulgaria 758
CA - Canada 461
TR - Turchia 424
SG - Singapore 405
GB - Regno Unito 387
VN - Vietnam 294
UA - Ucraina 284
FI - Finlandia 276
FR - Francia 187
IN - India 166
AT - Austria 130
HK - Hong Kong 127
CH - Svizzera 98
RU - Federazione Russa 86
NG - Nigeria 74
CI - Costa d'Avorio 67
BE - Belgio 50
SN - Senegal 38
JP - Giappone 29
GR - Grecia 26
AU - Australia 22
PL - Polonia 20
CZ - Repubblica Ceca 18
BR - Brasile 17
NL - Olanda 17
KR - Corea 11
MO - Macao, regione amministrativa speciale della Cina 11
IE - Irlanda 10
ES - Italia 9
ID - Indonesia 9
RO - Romania 9
NZ - Nuova Zelanda 8
IL - Israele 7
RS - Serbia 7
EU - Europa 6
IR - Iran 6
CL - Cile 5
DK - Danimarca 4
PT - Portogallo 4
BY - Bielorussia 3
DM - Dominica 3
DZ - Algeria 3
HU - Ungheria 3
SK - Slovacchia (Repubblica Slovacca) 3
TH - Thailandia 3
UY - Uruguay 3
AR - Argentina 2
HR - Croazia 2
KZ - Kazakistan 2
LI - Liechtenstein 2
LK - Sri Lanka 2
PK - Pakistan 2
SA - Arabia Saudita 2
TW - Taiwan 2
ZA - Sudafrica 2
A1 - Anonimo 1
AM - Armenia 1
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BD - Bangladesh 1
BN - Brunei Darussalam 1
EG - Egitto 1
IS - Islanda 1
KG - Kirghizistan 1
KW - Kuwait 1
LU - Lussemburgo 1
MM - Myanmar 1
MX - Messico 1
NO - Norvegia 1
PA - Panama 1
SC - Seychelles 1
TN - Tunisia 1
VE - Venezuela 1
Totale 27.873
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Città #
Woodbridge 2.643
Ann Arbor 1.943
Houston 1.589
Fairfield 1.584
Chandler 1.423
Serra 1.189
Ashburn 839
Sofia 757
Seattle 622
Wilmington 596
Cambridge 557
Beijing 469
Ottawa 434
New York 403
Izmir 401
Milan 381
Jacksonville 345
Princeton 339
Lawrence 294
Nanjing 260
Medford 259
Des Moines 182
Dearborn 164
Singapore 161
Dong Ket 136
Florence 132
Marseille 125
Hong Kong 122
Pisa 119
Vienna 117
Nanchang 116
Redwood City 91
London 90
Bern 87
San Diego 86
Lagos 74
Abidjan 67
Rome 66
Boulder 63
Ogden 62
Kunming 58
Nürnberg 58
Los Angeles 55
Jüchen 51
Pune 51
Shenyang 48
Dakar 38
Frankfurt am Main 38
Norwalk 37
Brussels 34
Hebei 33
Hefei 33
Boardman 32
Tianjin 32
Bremen 31
Pistoia 31
Jiaxing 29
Livorno 29
Grafing 28
Washington 26
Orange 23
Hangzhou 22
Auburn Hills 21
San Francisco 21
Hyderabad 20
Mumbai 20
Phoenix 19
Detroit 18
Falls Church 18
Jinan 18
Lancaster 18
Changsha 17
Carrara 16
Munich 15
Toronto 15
Brno 14
Guangzhou 14
Warsaw 14
Bologna 13
Indiana 13
Louvain-la-Neuve 13
Lucca 13
Caserta 11
Dallas 11
Lappeenranta 11
Zola Predosa 10
Costa Mesa 9
Chengdu 8
Düsseldorf 8
Frisco 8
Leawood 8
Macao 8
Montignoso 8
Pessac 8
Pieve Fosciana 8
Tokyo 8
Zhengzhou 8
Delhi 7
Grosseto 7
Helsinki 7
Totale 20.687
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Nome #
Cytotoxic Activity of Oleocanthal Isolated from Virgin Olive Oil on Human Melanoma Cells 258
COMPOSTO INIBITORE DELL’ENZIMA LATTATO DEIDROGENASI (LDH) E COMPOSIZIONE FARMACEUTICA CHE COMPRENDE TALE COMPOSTO 255
4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors 227
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 211
Synthesis and biological evaluation of non-glucose glycoconjugated N-hydroyxindole class LDH inhibitors as anticancer agents 179
Phenylpropanoids and flavonoids from Phlomis kurdica as inhibitors of human lactate dehydrogenase. 174
Identification of chemical byproducts in the radiofluorination of structurally complex aryliodonium salts 167
New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design,Synthesis, and Biopharmacological Properties 159
Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors 158
1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor 158
Diversity of yeast community composition in olive oil from two different areas in Tuscany 155
Design, synthesis and preliminary evaluation of (18)F-labelled 1,8-naphthyridin- and quinolin-2-one-3-carboxamide derivatives for PET imaging of CB2 cannabinoid receptor 154
Application of An Improved HPLC-FL Method to Screen Serine Palmitoyl Transferase Inhibitors 154
Oleocanthal and oleacein contribute to the in vitro therapeutic potential of extra virgin oil-derived extracts in non-melanoma skin cancer 154
Identification of the first synthetic allosteric modulator of the CB2receptors and evidence of its efficacy for neuropathic pain relief 150
Synthesis of Anthranylaldoxime Derivatives as Estrogen Receptor Ligands and Computational Prediction of Binding Modes 148
Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system 148
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 143
Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model 143
Anti-proliferative activity of oleocanthal in human malignant cutaneous melanoma cells 143
4-[6-(dansylamino)hexylamino]-7-methyl-2-phenyl-1,8-naphthyridine as a new potential fluorescent probe for studying A1-adenosine receptor 141
3-(METHYLENEAMINOXY)METHYLPIPERIDINE DERIVATIVES AS UPTAKE INHIBITORS OF BIOGENIC-AMINES IN THE BRAIN SYNAPTOSOMAL FRACTION 140
Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma 140
Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor 139
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 138
Efficient application of monolithic silica column to determination of illicit heroin street sample by HPLC 138
New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity 138
A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer 138
Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform a (LDH-A) as Starvation Agents against Cancer Cells 137
Synthesis and α2-adrenergic activity of 2-[(methyleneamino)oxy]-N-(guanidino)ethaneimines. A bioisosteric replacement of the aryl of guanabenz-type benzylideneaminoguanidine α2-agonists with the [(methyleneamino)oxy]methyl moiety (MAOMM) 136
Synthesis and dopaminergic properties of the two enantiomers of 3-(3,4-dimethylphenyl)-1-propylpiperidine, a potent and selective dopamine D4 receptor ligand 136
Phosphonomethylphosphorylmethyl(oxy)-analogues of geranylgeranyl diphosphate as stable and selective geranylgeranyl protein transferase inhibitors 136
Conformationally restrained β -blocking oxime ethers: synthesis and β -adrenergic properties of diastereoisomeric anti and syn 2-(5-isoxazolidinyl)ethanolamines 136
The [(Methyloxy)imino]methyl Moiety as a Bioisoster of Aryl. A Novel Class of Completely Aliphatic Beta-Adrenergic Receptor Antagonists 135
Dual Targeting of the Warburg Effect with a Glucose-Conjugated Lactate Dehydrogenase Inhibitor 135
Rational design, synthesis, biological evaluation and labelling of selective cannabinoid CB2 receptor agonists as anticancer agents 133
7-Nitrobenzofurazan (NBD)-Derivatives Of 5'-N-Ethylcarboxamidoadenosine (NECA) As New Fluorescent Probes For Human A3 Adenosine Receptors 133
Estrogen receptor ligands: a patent review update 133
Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor 133
COMPOUNDS INHIBITING THE ENZYME LACTATE DEHYDROGENASE (LDH), PHARMACEUTICAL COMPOSITIONS AND USES THEREOF 132
null 132
Development of an HPLC/UV assay for the evaluation of inhibitors of human recombinant monoacylglycerol lipase 131
Selective activators of estrogen receptor beta based on the aldoxime and ketoxime scaffolds 129
Inhibition of protein farnesylation enhances the chemotherapeutic efficacy of the novel geranylgeranyltransferase inhibitor BAL9611 in human colon cancer cells 129
3-(Methyleneaminoxy)methylpiperidine derivatives as uptake inhibitors of biogenic amines in the brain synaptosomal fraction 129
Dimer of rivastigmine and caffeic acid or ferulic acid, preparation method and drug composition thereof 129
HPLC determination of urinary 2,4- and 2,6-toluendiamines as potential degradation products of polyurethane breast implants 128
CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides 128
Synthesis of sulfonamide-containing N-hydroxyindole-2-carboxylates as inhibitors of human lactate dehydrogenase-isoform 5 127
Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands 127
Involvement of prenylated proteins in calcium signaling induced by LTD4 in differentiated U937 cells 125
Antiproliferative oxime derivatives that inhibit glucose transporter 1 (GLUT1) in cancer cells 125
Composition of health-promoting phenolic compounds in two extra-virgin olive oils and diversity of associated yeasts 125
Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials 125
Synthesis and ß-adrenergic properties of (E)-N-[3-(alkylamino)-2- hydroxypropilidene](methyloxy)amines substituted with an aromatic group on their [(methyloxy)imino]methyl moiety (MOIMM): an investigation into the biopharmacological effects of an aryl substitution in the class of MOIM ß-blocking drugs. 124
Preclinical emergence of novel lactate dehydrogenase inhibitors as potent antitumor agents in hypoxic models of pancreatic cancer: molecular mechanisms underlying their synergistic interaction with gemcitabine 124
Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds 124
A Virtual Screening Study for Lactate Dehydrogenase 5 Inhibitors by using a Pharmacophore-Based Approach 124
Polyprenyl phosphate biosynthesis in Mycobacterium tuberculosis and Mycobacterium smegmatis 123
SYNTHESIS, ANTIINFLAMMATORY ACTIVITY AND MOLECULAR-ORBITAL STUDIES OF A SERIES OF BENZYLIDENEAMINOXYPROPIONIC ACIDS SUBSTITUTED ON THE PHENYL RING 123
Synthesis of stable analogues of geranylgeranyl diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition 123
Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells 121
Ceramide analogues in apoptosis: a new strategy for anticancer drug development 121
Hypoxia-activated lysyl oxidase (LOX) inhibitors in the treatment of highly invasive and metastatic cancer 120
Metabolically labile cannabinoid esters: A ‘soft drug’ approach for the development of cannabinoid-based therapeutic drugs 120
Determination of water-soluble vitamins in multivitamin dietary supplements and in artichokes by micellar electrokinetic chromatography. 119
Conformationally Restrained Analogs of Sympathomimetic Catecholamines. Synthesis, Conformational Analysis, and Adrenergic Activity of Isochroman Derivatives 119
CONFORMATIONALLY RESTRAINED ANALOGS OF SYMPATHOMIMETIC CATECHOLAMINES - SYNTHESIS AND ADRENERGIC ACTIVITY OF TETRAHYDROBENZOCYCLOHEPTENE DERIVATIVES 118
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2) 118
Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein 118
The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation 118
Bioreductively Activated Lysyl Oxidase Inhibitors against Hypoxic Tumours 117
Effects on Immune Cells of a New 1,8-Naphthyridin-2-One Derivative and Its Analogues as Selective CB2 Agonists: Implications in Multiple Sclerosis 117
Oxime-based inhibitors of glucose transporter 1 displaying antiproliferative effects in cancer cells 117
Conformationally restrained ß-blocking oxime ethers. 2. Synthesis and ß-adrenergic properties of diastereoisomeric anti and syn 2-(5’-(3’-aryl-substituted)isoxazolidinyl)-N-alkylethanolamines 116
Role of the benzylic hydroxyl group of adrenergic catecholamines in eliciting a-adrenergic activity. Synthesis and a1- and a2-adrenergic activity of 3-phenyl-3-piperidinols and of their desoxy analogs 116
Diaryl-substituted salicyl- and anthranyl-ketoximes as potential estrogen receptor ligands 115
Synthesis of a Resveratrol Analogue with High Ceramide-Mediated Proapoptotic Activity on Human Breast Cancer Cells 115
Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: An investigation of the 1,8-naphthyridin-2(1H)-one scaffold 115
New N-n-propyl-substituted 3-Aryl and 3-Cyclohexyl piperidines as partial agonists at the D4 dopamine receptor 115
SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity 115
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors 115
Glycosaminoglycans provide a binding site for thyroglobulin in orbital tissues of patients with thyroid-associated ophthalmopathy 114
Geranylgeranyl diphosphate-based inhibitors of post-translational geranylgeranylation of cellular proteins 114
Synthesis and antimicrobial activity of 7ß-(S) and 7ß-(R)-3-(methyleneaminoxy)-2-methylpropionamido substituted cephalosporanic acid derivatives 113
Simultaneous detection and quantification of parecoxib and valdecoxib in canine plasma by HPLC with spectrofluorimetric detection: development and validation of a new methodology. 113
N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation 113
Synthesis of analogues of 5-iodo-2'-deoxyuridine-5'-diphosphate 112
Radiosensitizing potentialof small organic molecules toward hypoxic tumor cells in the radiotherapy 111
2-(Methyleneaminoxy)methylmorpholine derivatives. Synthesis and antidepressant activity 111
Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors 111
Synthesis and aldose reductase inhibitory activity of N-(arylsulfonyl)- and N-(aroyl)-N-(arylmethyloxy)glycines 110
Development of Methods for Recovering Endotoxins from Surfaces and from Air in Production Environment of Injectable Drugs 110
Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors 109
BACE1 inhibitory activities of enantiomerically pure, variously substituted N-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl) arylsulfonamides 108
Antiproliferative activity and cell cycle analysis of 2-(3,5-dihydroxyphenyl)-6-hydroxybenzothiazole on MCF-7 breast and HCT-15 colon cancer cell lines. 108
Synthesis and antiviral properties of novel analogues of monophosphate and diphosphate bioactive forms of acyclovir 108
Waste autochthonous tuscan olive leaves (Olea europaea var. olivastra seggianese) as antioxidant source for biomedicine 108
(Z)-(Methyloxyiminomethyl)ethanolamines. Effects of the configuration around the iminic double bond on the beta-adrenergic affinity of moim-type beta-adrenergic blocking agents 107
Triazole-substituted N-hydroxyindol-2-carboxylates as inhibitors of isoform 5 of human lactate dehydrogenase (hLDH5) 107
Totale 13.271
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Categoria #
all - tutte 72.693
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 72.693
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20204.284 0 347 657 273 386 541 526 334 382 288 391 159
2020/20212.463 182 121 121 145 259 152 149 306 302 201 162 363
2021/20223.666 99 344 93 225 572 477 137 179 135 118 208 1.079
2022/20234.448 568 605 344 376 513 580 53 336 685 32 259 97
2023/20242.668 310 283 296 118 401 501 173 68 49 59 103 307
2024/202567 52 15 0 0 0 0 0 0 0 0 0 0
Totale 28.487