CINECA IRIS Institutional Research Information System

MACCHIA, MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 17.912
EU - Europa 8.426
AS - Asia 4.130
AF - Africa 201
SA - Sud America 111
OC - Oceania 30
Continente sconosciuto - Info sul continente non disponibili 7
Totale 30.817
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Nazione #
US - Stati Uniti d'America 17.442
IT - Italia 3.327
CN - Cina 2.097
SE - Svezia 1.531
DE - Germania 1.106
SG - Singapore 810
BG - Bulgaria 750
TR - Turchia 533
CA - Canada 460
GB - Regno Unito 389
VN - Vietnam 290
FI - Finlandia 284
UA - Ucraina 279
FR - Francia 187
IN - India 165
RU - Federazione Russa 138
AT - Austria 131
HK - Hong Kong 127
CH - Svizzera 97
BR - Brasile 93
NG - Nigeria 73
CI - Costa d'Avorio 65
BE - Belgio 54
SN - Senegal 36
JP - Giappone 31
GR - Grecia 24
AU - Australia 22
NL - Olanda 21
PL - Polonia 19
CZ - Repubblica Ceca 18
BJ - Benin 12
IE - Irlanda 11
KR - Corea 11
MO - Macao, regione amministrativa speciale della Cina 11
ES - Italia 10
IL - Israele 9
RO - Romania 9
ID - Indonesia 8
NZ - Nuova Zelanda 8
RS - Serbia 7
AR - Argentina 6
EU - Europa 6
IR - Iran 6
CL - Cile 5
LT - Lituania 5
BY - Bielorussia 4
DK - Danimarca 4
IQ - Iraq 4
PT - Portogallo 4
SK - Slovacchia (Repubblica Slovacca) 4
ZA - Sudafrica 4
DM - Dominica 3
DZ - Algeria 3
EG - Egitto 3
HU - Ungheria 3
MX - Messico 3
PK - Pakistan 3
TH - Thailandia 3
UY - Uruguay 3
AZ - Azerbaigian 2
BD - Bangladesh 2
EC - Ecuador 2
HR - Croazia 2
KG - Kirghizistan 2
KZ - Kazakistan 2
LI - Liechtenstein 2
LK - Sri Lanka 2
MA - Marocco 2
OM - Oman 2
SA - Arabia Saudita 2
TN - Tunisia 2
TW - Taiwan 2
UZ - Uzbekistan 2
A1 - Anonimo 1
AL - Albania 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BN - Brunei Darussalam 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
HN - Honduras 1
IS - Islanda 1
KW - Kuwait 1
LU - Lussemburgo 1
MM - Myanmar 1
NO - Norvegia 1
PA - Panama 1
PY - Paraguay 1
SC - Seychelles 1
SI - Slovenia 1
VE - Venezuela 1
Totale 30.817
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Città #
Woodbridge 2.569
Ann Arbor 1.935
Houston 1.575
Fairfield 1.551
Chandler 1.413
Serra 1.182
Santa Clara 1.135
Ashburn 870
Sofia 749
Shanghai 641
Seattle 612
Wilmington 586
Cambridge 543
Beijing 469
Singapore 463
Ottawa 431
New York 398
Izmir 385
Milan 365
Boardman 348
Jacksonville 339
Princeton 335
Lawrence 290
Nanjing 257
Medford 255
Des Moines 176
Dearborn 163
Pisa 140
Florence 137
Dong Ket 131
Istanbul 130
Marseille 124
Hong Kong 122
Vienna 118
Nanchang 115
London 93
Redwood City 91
Bern 86
San Diego 86
Rome 78
Lagos 73
Abidjan 65
Boulder 63
Ogden 61
Kunming 58
Nürnberg 56
Los Angeles 55
Jüchen 51
Fuzhou 50
Pune 50
Shenyang 50
Frankfurt am Main 42
Brussels 38
Norwalk 37
Dakar 36
Lucca 35
Dallas 34
Livorno 34
Tianjin 33
Hebei 32
Hefei 32
Bremen 31
Pistoia 31
Jiaxing 28
Grafing 26
Washington 25
Hangzhou 23
Orange 22
Quanzhou 22
San Francisco 22
Auburn Hills 21
Guangzhou 21
Helsinki 20
Hyderabad 20
Mumbai 20
Munich 20
Detroit 18
Falls Church 18
Lancaster 18
Phoenix 18
Jinan 17
Toronto 17
Carrara 16
Changsha 16
Brno 14
Bologna 13
Indiana 13
Louvain-la-Neuve 13
Warsaw 13
Wuhan 13
Cotonou 12
Caserta 11
Lappeenranta 11
Belo Horizonte 10
Zola Predosa 10
Costa Mesa 9
Naples 9
Perugia 9
São Paulo 9
Tokyo 9
Totale 23.139
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Nome #
COMPOSTO INIBITORE DELL’ENZIMA LATTATO DEIDROGENASI (LDH) E COMPOSIZIONE FARMACEUTICA CHE COMPRENDE TALE COMPOSTO 280
Cytotoxic Activity of Oleocanthal Isolated from Virgin Olive Oil on Human Melanoma Cells 275
4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors 241
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 225
Synthesis and biological evaluation of non-glucose glycoconjugated N-hydroyxindole class LDH inhibitors as anticancer agents 190
Phenylpropanoids and flavonoids from Phlomis kurdica as inhibitors of human lactate dehydrogenase. 185
Identification of chemical byproducts in the radiofluorination of structurally complex aryliodonium salts 178
New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design,Synthesis, and Biopharmacological Properties 171
1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor 170
Diversity of yeast community composition in olive oil from two different areas in Tuscany 169
Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors 168
Application of An Improved HPLC-FL Method to Screen Serine Palmitoyl Transferase Inhibitors 168
Design, synthesis and preliminary evaluation of (18)F-labelled 1,8-naphthyridin- and quinolin-2-one-3-carboxamide derivatives for PET imaging of CB2 cannabinoid receptor 166
Oleocanthal and oleacein contribute to the in vitro therapeutic potential of extra virgin oil-derived extracts in non-melanoma skin cancer 166
Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system 162
Identification of the first synthetic allosteric modulator of the CB2receptors and evidence of its efficacy for neuropathic pain relief 162
Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials 162
Synthesis of Anthranylaldoxime Derivatives as Estrogen Receptor Ligands and Computational Prediction of Binding Modes 158
CONFORMATIONALLY RESTRAINED ANALOGS OF SYMPATHOMIMETIC CATECHOLAMINES - SYNTHESIS AND ADRENERGIC ACTIVITY OF TETRAHYDROBENZOCYCLOHEPTENE DERIVATIVES 157
Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model 156
3-(METHYLENEAMINOXY)METHYLPIPERIDINE DERIVATIVES AS UPTAKE INHIBITORS OF BIOGENIC-AMINES IN THE BRAIN SYNAPTOSOMAL FRACTION 155
The [(Methyloxy)imino]methyl Moiety as a Bioisoster of Aryl. A Novel Class of Completely Aliphatic Beta-Adrenergic Receptor Antagonists 155
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 154
New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity 154
Anti-proliferative activity of oleocanthal in human malignant cutaneous melanoma cells 154
Synthesis and dopaminergic properties of the two enantiomers of 3-(3,4-dimethylphenyl)-1-propylpiperidine, a potent and selective dopamine D4 receptor ligand 152
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 152
4-[6-(dansylamino)hexylamino]-7-methyl-2-phenyl-1,8-naphthyridine as a new potential fluorescent probe for studying A1-adenosine receptor 152
Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma 152
Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor 151
Efficient application of monolithic silica column to determination of illicit heroin street sample by HPLC 148
Estrogen receptor ligands: a patent review update 148
Phosphonomethylphosphorylmethyl(oxy)-analogues of geranylgeranyl diphosphate as stable and selective geranylgeranyl protein transferase inhibitors 147
A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer 147
Rational design, synthesis, biological evaluation and labelling of selective cannabinoid CB2 receptor agonists as anticancer agents 146
Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform a (LDH-A) as Starvation Agents against Cancer Cells 145
3-(Methyleneaminoxy)methylpiperidine derivatives as uptake inhibitors of biogenic amines in the brain synaptosomal fraction 145
Synthesis and α2-adrenergic activity of 2-[(methyleneamino)oxy]-N-(guanidino)ethaneimines. A bioisosteric replacement of the aryl of guanabenz-type benzylideneaminoguanidine α2-agonists with the [(methyleneamino)oxy]methyl moiety (MAOMM) 144
7-Nitrobenzofurazan (NBD)-Derivatives Of 5'-N-Ethylcarboxamidoadenosine (NECA) As New Fluorescent Probes For Human A3 Adenosine Receptors 144
Dual Targeting of the Warburg Effect with a Glucose-Conjugated Lactate Dehydrogenase Inhibitor 144
Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor 144
Development of an HPLC/UV assay for the evaluation of inhibitors of human recombinant monoacylglycerol lipase 143
Selective and potent agonists for estrogen receptor beta derived from molecular refinements of salicylaldoximes 141
Inhibition of protein farnesylation enhances the chemotherapeutic efficacy of the novel geranylgeranyltransferase inhibitor BAL9611 in human colon cancer cells 140
CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides 140
Dimer of rivastigmine and caffeic acid or ferulic acid, preparation method and drug composition thereof 140
Composition of health-promoting phenolic compounds in two extra-virgin olive oils and diversity of associated yeasts 140
COMPOUNDS INHIBITING THE ENZYME LACTATE DEHYDROGENASE (LDH), PHARMACEUTICAL COMPOSITIONS AND USES THEREOF 139
Selective activators of estrogen receptor beta based on the aldoxime and ketoxime scaffolds 138
Synthesis of sulfonamide-containing N-hydroxyindole-2-carboxylates as inhibitors of human lactate dehydrogenase-isoform 5 137
Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands 137
Preclinical emergence of novel lactate dehydrogenase inhibitors as potent antitumor agents in hypoxic models of pancreatic cancer: molecular mechanisms underlying their synergistic interaction with gemcitabine 136
HPLC determination of urinary 2,4- and 2,6-toluendiamines as potential degradation products of polyurethane breast implants 135
Synthesis of stable analogues of geranylgeranyl diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition 135
Biphenyl-Derivatives Possessing Tertiary Amino Groups as ß-Secretase (BACE1) Inhibitors 135
Antiproliferative oxime derivatives that inhibit glucose transporter 1 (GLUT1) in cancer cells 135
Synthesis and ß-adrenergic properties of (E)-N-[3-(alkylamino)-2- hydroxypropilidene](methyloxy)amines substituted with an aromatic group on their [(methyloxy)imino]methyl moiety (MOIMM): an investigation into the biopharmacological effects of an aryl substitution in the class of MOIM ß-blocking drugs. 134
Involvement of prenylated proteins in calcium signaling induced by LTD4 in differentiated U937 cells 134
Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds 134
A Virtual Screening Study for Lactate Dehydrogenase 5 Inhibitors by using a Pharmacophore-Based Approach 134
Polyprenyl phosphate biosynthesis in Mycobacterium tuberculosis and Mycobacterium smegmatis 133
Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein 133
Hypoxia-activated lysyl oxidase (LOX) inhibitors in the treatment of highly invasive and metastatic cancer 132
SYNTHESIS, ANTIINFLAMMATORY ACTIVITY AND MOLECULAR-ORBITAL STUDIES OF A SERIES OF BENZYLIDENEAMINOXYPROPIONIC ACIDS SUBSTITUTED ON THE PHENYL RING 132
Effects on Immune Cells of a New 1,8-Naphthyridin-2-One Derivative and Its Analogues as Selective CB2 Agonists: Implications in Multiple Sclerosis 132
null 132
Ceramide analogues in apoptosis: a new strategy for anticancer drug development 131
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2) 131
Synthesis and adrenergic ß-blocking activity of (oxypropanolamino)-substituted [(benzylideneamino)oxy]propanolamines 130
Determination of water-soluble vitamins in multivitamin dietary supplements and in artichokes by micellar electrokinetic chromatography. 130
Conformationally Restrained Analogs of Sympathomimetic Catecholamines. Synthesis, Conformational Analysis, and Adrenergic Activity of Isochroman Derivatives 130
2-(Methyleneaminoxy)methylmorpholine derivatives. Synthesis and antidepressant activity 129
Bioreductively Activated Lysyl Oxidase Inhibitors against Hypoxic Tumours 128
SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity 128
The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation 128
Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells 127
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors 127
Conformationally restrained ß-blocking oxime ethers. 2. Synthesis and ß-adrenergic properties of diastereoisomeric anti and syn 2-(5’-(3’-aryl-substituted)isoxazolidinyl)-N-alkylethanolamines 126
Metabolically labile cannabinoid esters: A ‘soft drug’ approach for the development of cannabinoid-based therapeutic drugs 126
Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: An investigation of the 1,8-naphthyridin-2(1H)-one scaffold 126
Glycosaminoglycans provide a binding site for thyroglobulin in orbital tissues of patients with thyroid-associated ophthalmopathy 126
Oxime-based inhibitors of glucose transporter 1 displaying antiproliferative effects in cancer cells 126
Synthesis of a Resveratrol Analogue with High Ceramide-Mediated Proapoptotic Activity on Human Breast Cancer Cells 125
New N-n-propyl-substituted 3-Aryl and 3-Cyclohexyl piperidines as partial agonists at the D4 dopamine receptor 125
Diaryl-substituted salicyl- and anthranyl-ketoximes as potential estrogen receptor ligands 124
Simultaneous detection and quantification of parecoxib and valdecoxib in canine plasma by HPLC with spectrofluorimetric detection: development and validation of a new methodology. 124
N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation 124
Conformationally restrained beta-blocking oxime ethers: synthesis and beta-adrenergic properties of diastereoisomeric anti and syn 2-(5-isoxazolidinyl)ethanolamines 123
Synthesis and aldose reductase inhibitory activity of N-(arylsulfonyl)- and N-(aroyl)-N-(arylmethyloxy)glycines 122
Geranylgeranyl diphosphate-based inhibitors of post-translational geranylgeranylation of cellular proteins 122
Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors 122
Synthesis and antimicrobial activity of 7ß-(S) and 7ß-(R)-3-(methyleneaminoxy)-2-methylpropionamido substituted cephalosporanic acid derivatives 121
Variously substituted (phosphonoacetamido)oxy analogues of geranylgeranyl diphosphate (GGdP) as GGdP-transferase (GGTase) inhibitors and antiproliferative agents 121
BACE1 inhibitory activities of enantiomerically pure, variously substituted N-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl) arylsulfonamides 120
Synthesis of analogues of 5-iodo-2'-deoxyuridine-5'-diphosphate 120
(Z)-(Methyloxyiminomethyl)ethanolamines. Effects of the configuration around the iminic double bond on the beta-adrenergic affinity of moim-type beta-adrenergic blocking agents 119
Synthesis of aniline-type analogues of farnesyl diphosphate and their biological assays for prenyl protein transferase inhibitory activity 119
Allosteric modulators targeting cannabinoid cb1 and cb2 receptors: Implications for drug discovery 119
Design, synthesis, and characterization of the antitumor activity of novel ceramide analogues 118
Triazole-substituted N-hydroxyindol-2-carboxylates as inhibitors of isoform 5 of human lactate dehydrogenase (hLDH5) 118
Totale 14.478
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Categoria #
all - tutte 83.934
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 83.934
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20202.033 0 0 0 0 0 0 514 325 373 284 386 151
2020/20212.424 179 119 119 145 257 150 147 295 298 197 162 356
2021/20223.614 99 342 93 217 563 472 136 176 132 116 204 1.064
2022/20234.384 558 598 336 374 509 569 51 333 674 32 254 96
2023/20242.618 304 275 291 114 389 495 173 65 48 58 102 304
2024/20253.473 52 381 213 595 923 976 333 0 0 0 0 0
Totale 31.452