CINECA IRIS Institutional Research Information System

MACCHIA, MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 27.281
AS - Asia 11.912
EU - Europa 10.713
SA - Sud America 1.762
Continente sconosciuto - Info sul continente non disponibili 736
AF - Africa 447
OC - Oceania 37
Totale 52.888
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Nazione #
US - Stati Uniti d'America 26.422
IT - Italia 3.940
SG - Singapore 3.755
CN - Cina 3.356
HK - Hong Kong 1.763
SE - Svezia 1.585
BR - Brasile 1.446
DE - Germania 1.400
VN - Vietnam 884
BG - Bulgaria 756
CA - Canada 629
TR - Turchia 593
FR - Francia 578
GB - Regno Unito 564
FI - Finlandia 472
IN - India 367
RU - Federazione Russa 362
UA - Ucraina 304
KR - Corea 285
JP - Giappone 267
AT - Austria 163
CH - Svizzera 116
NL - Olanda 108
BD - Bangladesh 99
AR - Argentina 98
NG - Nigeria 78
IQ - Iraq 72
MX - Messico 72
CI - Costa d'Avorio 71
PK - Pakistan 66
PL - Polonia 65
ZA - Sudafrica 60
SA - Arabia Saudita 58
BE - Belgio 57
ID - Indonesia 55
MA - Marocco 55
ES - Italia 54
EC - Ecuador 46
UZ - Uzbekistan 46
CO - Colombia 42
SN - Senegal 39
VE - Venezuela 39
JM - Giamaica 37
AU - Australia 29
GR - Grecia 29
KE - Kenya 27
CZ - Repubblica Ceca 25
PY - Paraguay 24
CL - Cile 22
CR - Costa Rica 22
EG - Egitto 22
IL - Israele 22
LT - Lituania 21
IE - Irlanda 20
MY - Malesia 20
AZ - Azerbaigian 18
TN - Tunisia 18
TT - Trinidad e Tobago 18
UY - Uruguay 17
KZ - Kazakistan 16
PE - Perù 16
AE - Emirati Arabi Uniti 15
PH - Filippine 15
DZ - Algeria 14
JO - Giordania 14
NP - Nepal 14
PA - Panama 13
BJ - Benin 12
BY - Bielorussia 12
ET - Etiopia 12
BB - Barbados 11
DO - Repubblica Dominicana 11
MO - Macao, regione amministrativa speciale della Cina 11
RO - Romania 11
RS - Serbia 11
GE - Georgia 10
IR - Iran 10
PR - Porto Rico 9
PS - Palestinian Territory 9
BO - Bolivia 8
GT - Guatemala 8
HN - Honduras 8
NZ - Nuova Zelanda 8
OM - Oman 8
TH - Thailandia 8
BA - Bosnia-Erzegovina 7
LB - Libano 7
PT - Portogallo 7
SK - Slovacchia (Repubblica Slovacca) 7
AL - Albania 6
AO - Angola 6
EU - Europa 6
GA - Gabon 6
HR - Croazia 6
NI - Nicaragua 6
QA - Qatar 6
TW - Taiwan 6
KG - Kirghizistan 5
SV - El Salvador 5
BN - Brunei Darussalam 4
Totale 52.062
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Città #
Ashburn 2.968
Woodbridge 2.570
Singapore 2.160
Ann Arbor 1.935
Hong Kong 1.743
Houston 1.610
San Jose 1.594
Fairfield 1.551
Chandler 1.413
Santa Clara 1.217
Serra 1.186
Dallas 1.103
Sofia 754
Shanghai 709
Beijing 673
Seattle 625
Wilmington 589
Council Bluffs 579
Cambridge 546
New York 510
Ottawa 435
Milan 402
Los Angeles 392
Izmir 386
Hefei 379
Boardman 361
Jacksonville 347
Princeton 336
Lawrence 290
Seoul 271
Lauterbourg 269
Medford 258
Nanjing 258
Tokyo 229
Ho Chi Minh City 217
Pisa 198
Des Moines 181
Munich 174
Dearborn 163
Buffalo 160
Florence 156
São Paulo 154
Istanbul 144
Vienna 136
Dong Ket 131
Helsinki 130
Marseille 126
Redondo Beach 126
Hanoi 125
London 124
Rome 119
Columbus 117
Nanchang 117
The Dalles 96
Redwood City 91
San Diego 91
Frankfurt am Main 89
Bern 86
Chicago 81
Orem 81
Lagos 77
Lucca 70
Abidjan 69
Turku 69
Boulder 63
Ogden 61
Kunming 58
Phoenix 57
San Francisco 57
Nürnberg 56
Pune 55
Jüchen 51
Shenyang 51
Toronto 51
Fuzhou 50
Warsaw 46
Livorno 45
Belo Horizonte 44
Montreal 43
Tashkent 41
Chennai 40
Brooklyn 39
Brussels 39
Dakar 39
Mumbai 39
Nuremberg 38
Düsseldorf 37
Norwalk 37
Guangzhou 36
Jakarta 36
Denver 35
Tianjin 35
Baghdad 34
Washington 33
Amsterdam 32
Hebei 32
Rio de Janeiro 32
Atlanta 31
Bremen 31
Pistoia 31
Totale 35.881
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Nome #
Cytotoxic Activity of Oleocanthal Isolated from Virgin Olive Oil on Human Melanoma Cells 379
COMPOSTO INIBITORE DELL’ENZIMA LATTATO DEIDROGENASI (LDH) E COMPOSIZIONE FARMACEUTICA CHE COMPRENDE TALE COMPOSTO 366
4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors 337
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 309
Synthesis and biological evaluation of (Hetero)aryl-methyloxyphenyl derivatives as potent P-glycoprotein modulating agents. 282
Olive Mill Wastewater as Source of Polyphenols with Nutraceutical Properties 274
Phenylpropanoids and flavonoids from Phlomis kurdica as inhibitors of human lactate dehydrogenase. 270
Oleocanthal and oleacein contribute to the in vitro therapeutic potential of extra virgin oil-derived extracts in non-melanoma skin cancer 266
Diversity of yeast community composition in olive oil from two different areas in Tuscany 256
Identification of chemical byproducts in the radiofluorination of structurally complex aryliodonium salts 253
Application of An Improved HPLC-FL Method to Screen Serine Palmitoyl Transferase Inhibitors 253
Synthesis and biological evaluation of non-glucose glycoconjugated N-hydroyxindole class LDH inhibitors as anticancer agents 242
Identification of the first synthetic allosteric modulator of the CB2receptors and evidence of its efficacy for neuropathic pain relief 240
New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity 239
Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor 234
Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system 230
Structural optimization of 4-chlorobenzoylpiperidine derivatives for the development of potent, reversible and selective monoacylglycerol lipase (MAGL) inhibitors 229
Anti-proliferative activity of oleocanthal in human malignant cutaneous melanoma cells 229
Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors 227
New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design,Synthesis, and Biopharmacological Properties 226
A Virtual Screening Study for Lactate Dehydrogenase 5 Inhibitors by using a Pharmacophore-Based Approach 226
Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor 225
Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors 225
Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors 225
Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma 223
1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor 222
Rational Development of MAGL Inhibitors 218
HPLC determination of urinary 2,4- and 2,6-toluendiamines as potential degradation products of polyurethane breast implants 216
Synthesis of stable analogues of geranylgeranyl diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition 214
Antiproliferative oxime derivatives that inhibit glucose transporter 1 (GLUT1) in cancer cells 214
Synthesis of Anthranylaldoxime Derivatives as Estrogen Receptor Ligands and Computational Prediction of Binding Modes 213
Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands 213
The [(Methyloxy)imino]methyl Moiety as a Bioisoster of Aryl. A Novel Class of Completely Aliphatic Beta-Adrenergic Receptor Antagonists 212
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 210
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 210
SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity 210
Composition of health-promoting phenolic compounds in two extra-virgin olive oils and diversity of associated yeasts 210
Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials 210
Synthesis and pharmacological evaluation of new biphenylic derivatives as CB2 receptor ligands 210
Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors 209
Synthesis and α2-adrenergic activity of 2-[(methyleneamino)oxy]-N-(guanidino)ethaneimines. A bioisosteric replacement of the aryl of guanabenz-type benzylideneaminoguanidine α2-agonists with the [(methyleneamino)oxy]methyl moiety (MAOMM) 209
Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors 209
Allosteric modulators targeting cannabinoid cb1 and cb2 receptors: Implications for drug discovery 209
The phenolic compounds tyrosol and hydroxytyrosol counteract liver fibrogenesis via the transcriptional modulation of NADPH oxidases and oxidative stress-related miRNAs 208
Waste autochthonous tuscan olive leaves (Olea europaea var. olivastra seggianese) as antioxidant source for biomedicine 208
Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform a (LDH-A) as Starvation Agents against Cancer Cells 207
Efficient application of monolithic silica column to determination of illicit heroin street sample by HPLC 207
Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein 207
The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation 207
Rational design, synthesis, biological evaluation and labelling of selective cannabinoid CB2 receptor agonists as anticancer agents 206
Dual Targeting of the Warburg Effect with a Glucose-Conjugated Lactate Dehydrogenase Inhibitor 206
3-(METHYLENEAMINOXY)METHYLPIPERIDINE DERIVATIVES AS UPTAKE INHIBITORS OF BIOGENIC-AMINES IN THE BRAIN SYNAPTOSOMAL FRACTION 205
Dimer of rivastigmine and caffeic acid or ferulic acid, preparation method and drug composition thereof 205
CONFORMATIONALLY RESTRAINED ANALOGS OF SYMPATHOMIMETIC CATECHOLAMINES - SYNTHESIS AND ADRENERGIC ACTIVITY OF TETRAHYDROBENZOCYCLOHEPTENE DERIVATIVES 204
COMPOUNDS INHIBITING THE ENZYME LACTATE DEHYDROGENASE (LDH), PHARMACEUTICAL COMPOSITIONS AND USES THEREOF 204
Development of an HPLC/UV assay for the evaluation of inhibitors of human recombinant monoacylglycerol lipase 204
Design, synthesis and preliminary evaluation of (18)F-labelled 1,8-naphthyridin- and quinolin-2-one-3-carboxamide derivatives for PET imaging of CB2 cannabinoid receptor 201
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors 201
Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors 201
Synthesis and dopaminergic properties of the two enantiomers of 3-(3,4-dimethylphenyl)-1-propylpiperidine, a potent and selective dopamine D4 receptor ligand 200
Phosphonomethylphosphorylmethyl(oxy)-analogues of geranylgeranyl diphosphate as stable and selective geranylgeranyl protein transferase inhibitors 200
4-[6-(dansylamino)hexylamino]-7-methyl-2-phenyl-1,8-naphthyridine as a new potential fluorescent probe for studying A1-adenosine receptor 200
(Z)-(Methyloxyiminomethyl)ethanolamines. Effects of the configuration around the iminic double bond on the beta-adrenergic affinity of moim-type beta-adrenergic blocking agents 198
New monoaryl-salicylaldoximes with improved ERbeta-selective agonist potency 197
Estrogen receptor ligands: a patent review update 196
CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides 196
VenomPred 2.0: A Novel In Silico Platform for an Extended and Human Interpretable Toxicological Profiling of Small Molecules 195
Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system 195
MolBook UNIPI─Create, Manage, Analyze, and Share Your Chemical Data for Free 194
A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer 194
Conformationally restrained ß-blocking oxime ethers. 2. Synthesis and ß-adrenergic properties of diastereoisomeric anti and syn 2-(5’-(3’-aryl-substituted)isoxazolidinyl)-N-alkylethanolamines 193
Hypoxia-activated lysyl oxidase (LOX) inhibitors in the treatment of highly invasive and metastatic cancer 193
Synthesis and ß-adrenergic properties of (E)-N-[3-(alkylamino)-2- hydroxypropilidene](methyloxy)amines substituted with an aromatic group on their [(methyloxy)imino]methyl moiety (MOIMM): an investigation into the biopharmacological effects of an aryl substitution in the class of MOIM ß-blocking drugs. 192
SYNTHESIS, ANTIINFLAMMATORY ACTIVITY AND MOLECULAR-ORBITAL STUDIES OF A SERIES OF BENZYLIDENEAMINOXYPROPIONIC ACIDS SUBSTITUTED ON THE PHENYL RING 192
Inhibition of protein farnesylation enhances the chemotherapeutic efficacy of the novel geranylgeranyltransferase inhibitor BAL9611 in human colon cancer cells 192
3-(Methyleneaminoxy)methylpiperidine derivatives as uptake inhibitors of biogenic amines in the brain synaptosomal fraction 192
Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model 192
Role of the benzylic hydroxyl group of adrenergic cattecholamines in eliciting alpha-adrenergic activity. Synthesis and alpha1- and alpha2-adrenergic activity of 3-phenyl-3-piperidinols and of their desoxy analogs 191
Variously substituted (phosphonoacetamido)oxy analogues of geranylgeranyl diphosphate (GGdP) as GGdP-transferase (GGTase) inhibitors and antiproliferative agents 191
A Proteomic Approach to Uncover Neuroprotective Mechanisms of Oleocanthal against Oxidative Stress 191
Conformationally Restrained Analogs of Sympathomimetic Catecholamines. Synthesis, Conformational Analysis, and Adrenergic Activity of Isochroman Derivatives 191
Involvement of prenylated proteins in calcium signaling induced by LTD4 in differentiated U937 cells 190
Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds 190
Conformationally restrained beta-blocking oxime ethers: synthesis and beta-adrenergic properties of diastereoisomeric anti and syn 2-(5-isoxazolidinyl)ethanolamines 189
Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells 189
QSAR models for predicting enzymatic hydrolysis of new chemical entities in 'soft-drug' design 189
Selective and potent agonists for estrogen receptor beta derived from molecular refinements of salicylaldoximes 188
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2) 187
Simultaneous detection and quantification of parecoxib and valdecoxib in canine plasma by HPLC with spectrofluorimetric detection: development and validation of a new methodology. 187
Diaryl-substituted salicyl- and anthranyl-ketoximes as potential estrogen receptor ligands 186
Selective activators of estrogen receptor beta based on the aldoxime and ketoxime scaffolds 185
N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation 185
1-benzilossiimmino-3- ammino-2-propanoli: sintesi e proprietà ß-adrenergiche 184
7-Nitrobenzofurazan (NBD)-Derivatives Of 5'-N-Ethylcarboxamidoadenosine (NECA) As New Fluorescent Probes For Human A3 Adenosine Receptors 184
2-(Methyleneaminoxy)methylmorpholine derivatives. Synthesis and antidepressant activity 183
Rutin content in the forage and grain of common buckwheat (Fagopyrum esculentum) as affected by sowing time and irrigation in a Mediterranean environment. 183
Fluorescent probes for adenosine receptors: synthesis and biology of n6-dansylaminoalkyl substituted neca derivatives 182
Synthesis and adrenergic ß-blocking activity of (oxypropanolamino)-substituted [(benzylideneamino)oxy]propanolamines 182
Synthesis and antimicrobial activity of 7ß-(S) and 7ß-(R)-3-(methyleneaminoxy)-2-methylpropionamido substituted cephalosporanic acid derivatives 181
Synthesis and aldose reductase inhibitory activity of some N-(aroyl)-N-(arylalkyloxy)-glycines and -beta-alanines 181
Totale 21.364
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Categoria #
all - tutte 145.916
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 145.916
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20223.173 0 0 93 217 563 472 136 176 132 116 204 1.064
2022/20234.384 558 598 336 374 509 569 51 333 674 32 254 96
2023/20242.610 304 275 291 114 386 495 172 65 48 57 100 303
2024/202510.225 52 379 213 592 919 959 849 586 1.002 1.336 1.152 2.186
2025/202611.569 889 1.468 1.374 961 1.033 1.069 1.733 584 727 954 490 287
2026/20273.123 312 1.123 1.688 0 0 0 0 0 0 0 0 0
Totale 52.888