CINECA IRIS Institutional Research Information System

DIGIACOMO, MARIA
 Distribuzione geografica
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Continente #
NA - Nord America 6.807
EU - Europa 3.242
AS - Asia 3.049
SA - Sud America 470
AF - Africa 119
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 2
Totale 13.697
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Nazione #
US - Stati Uniti d'America 6.588
IT - Italia 1.383
CN - Cina 972
SG - Singapore 924
HK - Hong Kong 548
SE - Svezia 457
DE - Germania 407
BR - Brasile 400
BG - Bulgaria 223
CA - Canada 182
VN - Vietnam 159
TR - Turchia 143
GB - Regno Unito 141
FI - Finlandia 113
RU - Federazione Russa 112
AT - Austria 106
FR - Francia 86
IN - India 74
KR - Corea 74
UA - Ucraina 53
JP - Giappone 39
CI - Costa d'Avorio 36
PL - Polonia 34
NL - Olanda 29
NG - Nigeria 23
AR - Argentina 22
CH - Svizzera 21
MX - Messico 17
BE - Belgio 16
CZ - Repubblica Ceca 16
BD - Bangladesh 14
ES - Italia 14
IQ - Iraq 12
PK - Pakistan 12
ZA - Sudafrica 12
MA - Marocco 11
IL - Israele 10
UZ - Uzbekistan 10
SA - Arabia Saudita 9
SN - Senegal 9
VE - Venezuela 9
AU - Australia 7
CL - Cile 7
CO - Colombia 7
EC - Ecuador 7
IR - Iran 7
LT - Lituania 7
PY - Paraguay 7
AZ - Azerbaigian 5
CR - Costa Rica 5
EG - Egitto 5
GR - Grecia 5
ID - Indonesia 5
IE - Irlanda 5
MY - Malesia 5
NP - Nepal 5
RO - Romania 5
BJ - Benin 4
DZ - Algeria 4
JM - Giamaica 4
KE - Kenya 4
KZ - Kazakistan 4
PE - Perù 4
UY - Uruguay 4
GA - Gabon 3
PS - Palestinian Territory 3
TT - Trinidad e Tobago 3
BB - Barbados 2
BO - Bolivia 2
BY - Bielorussia 2
ET - Etiopia 2
HN - Honduras 2
LB - Libano 2
LK - Sri Lanka 2
PT - Portogallo 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
TW - Taiwan 2
A1 - Anonimo 1
AE - Emirati Arabi Uniti 1
AL - Albania 1
AM - Armenia 1
AO - Angola 1
BH - Bahrain 1
BW - Botswana 1
CM - Camerun 1
DK - Danimarca 1
EU - Europa 1
GE - Georgia 1
GH - Ghana 1
GY - Guiana 1
KG - Kirghizistan 1
LI - Liechtenstein 1
LY - Libia 1
MM - Myanmar 1
MQ - Martinica 1
NI - Nicaragua 1
NZ - Nuova Zelanda 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
Totale 13.695
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Città #
Ashburn 786
Woodbridge 585
Fairfield 545
Hong Kong 544
Singapore 534
Serra 532
Houston 454
Dallas 423
Chandler 419
Santa Clara 396
Ann Arbor 389
Shanghai 230
Sofia 223
Beijing 221
Wilmington 219
Seattle 207
Cambridge 206
Milan 164
Ottawa 150
New York 137
Princeton 115
Boardman 114
Hefei 103
Los Angeles 95
Munich 94
Vienna 92
Lawrence 86
Izmir 84
Medford 80
Pisa 73
Seoul 66
Jacksonville 62
Nanjing 55
Des Moines 50
Buffalo 48
Frankfurt am Main 46
Istanbul 45
Dong Ket 41
London 39
Florence 38
Turku 37
Abidjan 36
Dearborn 34
Marseille 34
Rome 34
Redondo Beach 33
San Diego 33
São Paulo 33
Tokyo 32
Ogden 30
Boulder 29
Chicago 28
Warsaw 26
Nanchang 25
Ho Chi Minh City 23
Lagos 23
Lucca 23
Redwood City 20
Council Bluffs 19
Pistoia 19
Bern 18
Pune 18
Brussels 16
San Francisco 16
Shenyang 16
Auburn Hills 15
Brooklyn 15
Nürnberg 15
The Dalles 15
Belo Horizonte 14
Bremen 13
Düsseldorf 13
Fuzhou 13
Helsinki 13
Brno 12
Enterprise 12
Hanoi 12
Nuremberg 12
Tianjin 12
Hebei 11
Phoenix 11
Salt Lake City 11
Toronto 11
Washington 11
Brasília 10
Columbus 10
Groningen 10
Guangzhou 10
Livorno 10
Tashkent 10
Changsha 9
Dakar 9
Jüchen 9
Norwalk 9
Quanzhou 9
Stockholm 9
São Bernardo do Campo 9
Boston 8
Chengdu 8
Falkenstein 8
Totale 9.833
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Nome #
Cytotoxic Activity of Oleocanthal Isolated from Virgin Olive Oil on Human Melanoma Cells 337
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 278
Application of An Improved HPLC-FL Method to Screen Serine Palmitoyl Transferase Inhibitors 228
Oleocanthal and oleacein contribute to the in vitro therapeutic potential of extra virgin oil-derived extracts in non-melanoma skin cancer 226
Diversity of yeast community composition in olive oil from two different areas in Tuscany 218
Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system 213
Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications 212
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 212
New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design,Synthesis, and Biopharmacological Properties 207
A NEW NITRIC OXIDE RELEASING ANTI-DIABETIC HYBRID DRUG: FROM THE DESIGN TO THE PHARMACOLOGICAL CHARACTERIZATION 203
Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor 199
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease 195
Identification of the first synthetic allosteric modulator of the CB2receptors and evidence of its efficacy for neuropathic pain relief 194
Synthesis and AT1 affinity evaluation of benzamidophenyl analogs of known AT1 receptor ligands with similar aromatic skeleton 193
Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein 189
Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma 189
Design, synthesis and preliminary evaluation of (18)F-labelled 1,8-naphthyridin- and quinolin-2-one-3-carboxamide derivatives for PET imaging of CB2 cannabinoid receptor 185
SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity 183
The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation 183
In-vitro evaluation of new pharmacodynamic hybrids with insulin secretagogue and NO-donor activity 180
Dimer of rivastigmine and caffeic acid or ferulic acid, preparation method and drug composition thereof 179
Composition of health-promoting phenolic compounds in two extra-virgin olive oils and diversity of associated yeasts 179
Allosteric modulators targeting cannabinoid cb1 and cb2 receptors: Implications for drug discovery 179
Waste autochthonous tuscan olive leaves (Olea europaea var. olivastra seggianese) as antioxidant source for biomedicine 177
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors 176
Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system 175
Spirocyclic Benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel 173
Pharmacological study on the cardiovascular activity of no-sartans, pharmacodynamic hybridsexhibiting at1-antagonist and no-donor properties 170
ANTI-ISCHEMIC PROPERTIES OF A NEW SPIRO-CYCLIC BENZOPYRAN ACTIVATOR OF CARDIAC MITOCHONDRIAL ATP-SENSITIVE POTASSIUM CHANNELS 170
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 170
2-[(3-Methoxyphenylethyl)phenoxy]-based ABCB1 inhibitors: effect of different basic side-chains on their biological properties 168
A Proteomic Approach to Uncover Neuroprotective Mechanisms of Oleocanthal against Oxidative Stress 166
The phenolic compounds tyrosol and hydroxytyrosol counteract liver fibrogenesis via the transcriptional modulation of NADPH oxidases and oxidative stress-related miRNAs 165
NO-Sartans: A New Class of Pharmacodynamic Hybrids as Cardiovascular Drugs 164
Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel 164
Olive Mill Wastewater as Source of Polyphenols with Nutraceutical Properties 162
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease 161
Antiarrhythmic activity of a new spiro-cyclic benzopyran activator of the cardiac mitochondrial ATP dependent potassium channels 151
P-gp Transporter and its Role in Neurodegenerative Diseases 148
Antioxidant and neuroprotective activity of extra virgin olive oil extracts obtained from quercetano cultivar trees grown in different areas of the tuscany region (Italy) 148
Metabolically labile cannabinoid esters: A ‘soft drug’ approach for the development of cannabinoid-based therapeutic drugs 147
Therapeutic potential of sulindac hydroxamic acid against human pancreatic and colonic cancer cells 147
Synthesis and biological evaluation of (Hetero)aryl-methyloxyphenyl derivatives as potent P-glycoprotein modulating agents. 142
NO-glibenclamide derivatives: prototypes of a new class of nitric oxide-releasing anti-diabetic drugs 142
Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD 140
Evaluation of the NO-releasing properties of NO-donor linkers 139
In vitro investigation of sulindac derivatives as potential anticancer agents 138
Synthesis of new potent P-glycoprotein inhibitors and their screening: potential tools to reduce the multidrug resistance 137
Oleocanthalic acid from extra-virgin olive oil: Analysis, preparative isolation and radical scavenging activity 133
Synthesis and Affinity Evaluation for AT1 Receptor of Phenylsalicylaldoxime-Derivatives Structurally Related to Sartans 132
null 132
Electrospun Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate)/Olive Leaf Extract Fiber Mesh as Prospective Bio-Based Scaffold for Wound Healing 131
Immunomodulatory activity of electrospun polyhydroxyalkanoate fiber scaffolds incorporating olive leaf extract 128
alpha-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors 127
Sodium N-(Methylsulfonyl)-N-(4-nitro- 2-phenoxyphenyl)sulfamate: A Water-Soluble Nimesulide Prodrug for Parenteral Use 127
1-Phenylalkoxy-2-β-phenylethyl derivatives as P-glycoprotein (P-GP) inhibitors useful in drug resistance events 127
A Novel H2S-releasing Amino-Bisphosphonate which combines bone anti-catabolic and anabolic functions 126
Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis 124
In-vitro evaluation of new pharmacodynamic hybrids with insulin secretagogue and NO-donor activity 123
Synthesis and Biological Evaluation of (Hetero)Arylmethyloxy- and Arylmethylamine-phenyl Derivatives as Potent P-glycoprotein Modulating Agents 122
Enantioselectivity in Cardioprotection induced by (S)- (-)-2,2-Dimethyl-N-(4'-acetamido-benzyl)-4-spiromorpholone-chromane 120
Synthesis and Biological Evaluation of 2'-Oxo-2,3-dihydro-3'H-spiro[chromene-4,5'-[1,3]oxazolidin]3'il]acetic Acid Derivatives as Aldose reductase Inhibitors 120
The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis 118
miRNA Modulation and Antitumor Activity by the Extra-Virgin Olive Oil Polyphenol Oleacein in Human Melanoma Cells 117
Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (m TAAR1) Agonists 117
SYNTHESIS AND BIOLOGICAL EVALUATION OF 5-MEMBERED SPIRO HETEROCYCLE-BENZIPYRAN DERIVATIVES AGAINST MYOCARDIAL ISCHEMIA 115
Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1H)-One Scaffold 113
Unraveling the Protective Role of Oleocanthal and Its Oxidation Product, Oleocanthalic Acid, against Neuroinflammation 113
Pharmacodynamic hybrids with insulin secretagogue and NO-Donor activity 112
Pharmacodynamic hybrids with insulin secretagogue and NO-Donor activity 110
Predictive models, based on classification algorithms, for compounds potentially active as mitochondrial ATP-sensitive potassium channel openers 108
Synthesis and biological evaluation of new compounds as cannabinoid receptor type 1 allosteric modulators 106
The Extra Virgin Olive Oil Polyphenol Oleocanthal Exerts Antifibrotic Effects in the Liver 104
Insights into the Antioxidant/Antiradical Effects and In Vitro Intestinal Permeation of Oleocanthal and Its Metabolites Tyrosol and Oleocanthalic Acid 103
Enhanced Nutraceutical Properties of Extra Virgin Olive Oil Extract by Olive Leaf Enrichment 103
PSNCBAM-1 analogs: Structural evolutions and allosteric properties at cannabinoid CB1 receptor 103
Content Variations in Oleocanthalic Acid and Other Phenolic Compounds in Extra-Virgin Olive Oil during Storage 102
Phenolic Compounds in Prevention and Treatment of Skin Cancers: a review 101
Arylmethyloxyphenyl derivatives: small molecules displaying P-glycoprotein inhibition 100
Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease 97
Nitric Oxide Releasing and Hypoglycaemic Properties of a Glibenclamde-Related Pharmacodynamic Hybrid 91
A NOVEL NITRIC OXIDE RELEASING ANTI-DIABETIC DUAL DRUG: FROM THE DESIGN TO THE CHARACTERIZATION OF THE PHARMACOLOGICAL PROFILE 89
Comparative Analysis on Polyphenolic Composition of Different Olive Mill Wastewater and Related Extra Virgin Olive Oil Extracts and Evaluation of Nutraceutical Properties by Cell-Based Studies 87
IDENTIFICATION OF NEW PSNCBAM-1 DERIVATIVES AS CB1 RECEPTOR ALLOSTERIC MODULATORS 87
1-Acetoxypinoresinol, a Lignan from Olives: Insight into Its Characterization, Identification, and Nutraceutical Properties 85
NOVEL DIARYL UREA DERIVATIVES AS CANNABINOID TYPE 1 RECEPTOR ALLOSTERIC MODULATORS 85
Spiro-benzopyran structure: a new scaffold for cardioprotection 84
Fast, sensitive, and sustainable colorimetric detection of chlorogenic acid in artichoke waste material 82
NO-sartans: new class of potential cardiovascular drugs 82
null 82
Synthesis and biological evaluation of sulindac derivatives as potential anticancer agents 81
Synthesis and pharmacological activity of new nitric-oxide-donating antihypertensive drugs (NO-Sartans) 76
NO-sartans: new class of potential cardiovascular drugs 74
BACE-1 inhibitory activities of new substituted diphenyl-methylenyl-piperazines 74
alpha-Naphtylaminopropan-2-ol derivatives as BACE1 inhibitors 74
Dietary Bioactive Compounds: Implications for Oxidative Stress and Inflammation 67
Synthesis and biological evaluation of arylmethyloxy and heteroarylmethyloxy derivates as potent P-gp modulating agents 66
Variously substituted 2-oxopyridine derivatives: Extending the structure-activity relationships for allosteric modulation of the cannabinoid CB2 receptor 65
"Soft Drugs" Based on Cannabinoid Receptor Ligands as Potential Local Analgesic and Antiglaucoma Agents 65
New pharmacodynamic hybrids endowed of insuline secretagogue and NO-donor activities 64
Totale 13.975
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Categoria #
all - tutte 39.295
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 39.295
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021593 0 0 0 0 0 49 88 73 130 81 49 123
2021/20221.102 32 138 37 58 158 144 46 52 31 21 68 317
2022/20231.477 180 201 127 120 171 182 6 103 255 8 79 45
2023/2024915 97 110 116 45 142 144 62 14 18 16 50 101
2024/20253.303 18 133 88 190 312 318 300 183 346 449 380 586
2025/20262.094 284 485 480 325 402 118 0 0 0 0 0 0
Totale 14.054