DIGIACOMO, MARIA
 Distribuzione geografica
Continente #
NA - Nord America 4.792
EU - Europa 2.695
AS - Asia 794
AF - Africa 66
SA - Sud America 11
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 2
Totale 8.368
Nazione #
US - Stati Uniti d'America 4.633
IT - Italia 1.260
SE - Svezia 451
CN - Cina 331
DE - Germania 272
BG - Bulgaria 222
CA - Canada 158
SG - Singapore 140
GB - Regno Unito 100
AT - Austria 98
VN - Vietnam 98
TR - Turchia 89
FI - Finlandia 61
FR - Francia 60
HK - Hong Kong 51
UA - Ucraina 46
IN - India 45
RU - Federazione Russa 37
CI - Costa d'Avorio 35
NG - Nigeria 22
CH - Svizzera 21
PL - Polonia 17
CZ - Repubblica Ceca 14
BE - Belgio 13
JP - Giappone 12
SN - Senegal 8
AU - Australia 7
BR - Brasile 7
IL - Israele 6
IR - Iran 6
GR - Grecia 5
KR - Corea 5
RO - Romania 5
ES - Italia 4
IE - Irlanda 3
UY - Uruguay 3
KZ - Kazakistan 2
NL - Olanda 2
PK - Pakistan 2
SA - Arabia Saudita 2
A1 - Anonimo 1
AZ - Azerbaigian 1
BD - Bangladesh 1
CL - Cile 1
DK - Danimarca 1
DZ - Algeria 1
EU - Europa 1
LI - Liechtenstein 1
LK - Sri Lanka 1
MM - Myanmar 1
MX - Messico 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
TH - Thailandia 1
Totale 8.368
Città #
Woodbridge 585
Fairfield 545
Serra 532
Houston 450
Chandler 419
Ann Arbor 389
Ashburn 304
Sofia 222
Wilmington 218
Seattle 204
Cambridge 203
Milan 158
Ottawa 149
Beijing 147
Princeton 115
New York 112
Vienna 88
Lawrence 86
Izmir 83
Medford 80
Jacksonville 61
Nanjing 54
Pisa 52
Des Moines 50
Hong Kong 50
Dong Ket 41
Singapore 41
Abidjan 35
Florence 35
Dearborn 34
Marseille 34
San Diego 33
Frankfurt am Main 30
London 30
Ogden 30
Boulder 29
Rome 26
Nanchang 25
Lagos 22
Redwood City 20
Pistoia 19
Bern 18
Pune 17
Auburn Hills 15
Nürnberg 15
Shenyang 14
Bremen 13
Brussels 13
Los Angeles 13
Brno 12
Enterprise 12
Warsaw 12
Hebei 11
Lucca 11
San Francisco 10
Tianjin 10
Washington 10
Jüchen 9
Norwalk 9
Boardman 8
Changsha 8
Dakar 8
Livorno 8
Chengdu 7
San Giuliano Terme 7
Favria 6
Jiaxing 6
Morgantown 6
Munich 6
Phoenix 6
Porto Azzurro 6
Tokyo 6
Albenga 5
Berlin 5
Cascina 5
Fremont 5
Grosseto 5
Hefei 5
Hyderabad 5
Kunming 5
Lancaster 5
Lappeenranta 5
Toronto 5
Belo Horizonte 4
Bergamo 4
Bochum 4
Bologna 4
Falls Church 4
Genoa 4
Hangzhou 4
Montignoso 4
Orange 4
Palermo 4
Pessac 4
Bat Yam 3
Bientina 3
Carrara 3
Changchun 3
Chicago 3
Crotone 3
Totale 6.269
Nome #
Cytotoxic Activity of Oleocanthal Isolated from Virgin Olive Oil on Human Melanoma Cells 258
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 211
A NEW NITRIC OXIDE RELEASING ANTI-DIABETIC HYBRID DRUG: FROM THE DESIGN TO THE PHARMACOLOGICAL CHARACTERIZATION 161
New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design,Synthesis, and Biopharmacological Properties 159
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 155
Diversity of yeast community composition in olive oil from two different areas in Tuscany 155
Design, synthesis and preliminary evaluation of (18)F-labelled 1,8-naphthyridin- and quinolin-2-one-3-carboxamide derivatives for PET imaging of CB2 cannabinoid receptor 154
Application of An Improved HPLC-FL Method to Screen Serine Palmitoyl Transferase Inhibitors 154
Oleocanthal and oleacein contribute to the in vitro therapeutic potential of extra virgin oil-derived extracts in non-melanoma skin cancer 154
Identification of the first synthetic allosteric modulator of the CB2receptors and evidence of its efficacy for neuropathic pain relief 150
Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system 148
Diclofenac-Derived Hybrids for Treatment of Actinic Keratosis and Squamous Cell Carcinoma 140
Synthesis and AT1 affinity evaluation of benzamidophenyl analogs of known AT1 receptor ligands with similar aromatic skeleton 138
ANTI-ISCHEMIC PROPERTIES OF A NEW SPIRO-CYCLIC BENZOPYRAN ACTIVATOR OF CARDIAC MITOCHONDRIAL ATP-SENSITIVE POTASSIUM CHANNELS 136
2-[(3-Methoxyphenylethyl)phenoxy]-based ABCB1 inhibitors: effect of different basic side-chains on their biological properties 134
Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor 133
null 132
NO-Sartans: A New Class of Pharmacodynamic Hybrids as Cardiovascular Drugs 131
Anti-ischemic properties of a new spiro-cyclic benzopyran activator of the cardiac mito-KATP channel 131
Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications 130
Dimer of rivastigmine and caffeic acid or ferulic acid, preparation method and drug composition thereof 129
Antiarrhythmic activity of a new spiro-cyclic benzopyran activator of the cardiac mitochondrial ATP dependent potassium channels 129
In-vitro evaluation of new pharmacodynamic hybrids with insulin secretagogue and NO-donor activity 128
Pharmacological study on the cardiovascular activity of no-sartans, pharmacodynamic hybridsexhibiting at1-antagonist and no-donor properties 127
Composition of health-promoting phenolic compounds in two extra-virgin olive oils and diversity of associated yeasts 125
Synthesis and functional evaluation of novel aldose reductase inhibitors bearing a spirobenzopyran scaffold 121
Metabolically labile cannabinoid esters: A ‘soft drug’ approach for the development of cannabinoid-based therapeutic drugs 120
Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein 118
The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation 118
Spirocyclic Benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel 117
SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity 115
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors 115
P-gp Transporter and its Role in Neurodegenerative Diseases 112
Evaluation of the NO-releasing properties of NO-donor linkers 111
Nature-based molecules combined with rivastigmine: A symbiotic approach for the synthesis of new agents against Alzheimer's disease 110
Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease 108
Waste autochthonous tuscan olive leaves (Olea europaea var. olivastra seggianese) as antioxidant source for biomedicine 108
Allosteric modulators targeting cannabinoid cb1 and cb2 receptors: Implications for drug discovery 105
Therapeutic potential of sulindac hydroxamic acid against human pancreatic and colonic cancer cells 102
NO-glibenclamide derivatives: prototypes of a new class of nitric oxide-releasing anti-diabetic drugs 102
Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system 101
Synthesis and Affinity Evaluation for AT1 Receptor of Phenylsalicylaldoxime-Derivatives Structurally Related to Sartans 100
alpha-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors 100
A Proteomic Approach to Uncover Neuroprotective Mechanisms of Oleocanthal against Oxidative Stress 100
1-Phenylalkoxy-2-β-phenylethyl derivatives as P-glycoprotein (P-GP) inhibitors useful in drug resistance events 98
Synthesis and Biological Evaluation of (Hetero)Arylmethyloxy- and Arylmethylamine-phenyl Derivatives as Potent P-glycoprotein Modulating Agents 97
Synthesis of new potent P-glycoprotein inhibitors and their screening: potential tools to reduce the multidrug resistance 96
A Novel H2S-releasing Amino-Bisphosphonate which combines bone anti-catabolic and anabolic functions 94
In-vitro evaluation of new pharmacodynamic hybrids with insulin secretagogue and NO-donor activity 88
Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD 88
Enantioselectivity in Cardioprotection induced by (S)- (-)-2,2-Dimethyl-N-(4'-acetamido-benzyl)-4-spiromorpholone-chromane 87
Sodium N-(Methylsulfonyl)-N-(4-nitro- 2-phenoxyphenyl)sulfamate: A Water-Soluble Nimesulide Prodrug for Parenteral Use 86
SYNTHESIS AND BIOLOGICAL EVALUATION OF 5-MEMBERED SPIRO HETEROCYCLE-BENZIPYRAN DERIVATIVES AGAINST MYOCARDIAL ISCHEMIA 85
null 82
Traditional Uses of Cannabinoids and New Perspectives in the Treatment of Multiple Sclerosis 82
In vitro investigation of sulindac derivatives as potential anticancer agents 80
Pharmacodynamic hybrids with insulin secretagogue and NO-Donor activity 79
Synthesis and biological evaluation of (Hetero)aryl-methyloxyphenyl derivatives as potent P-glycoprotein modulating agents. 78
Arylmethyloxyphenyl derivatives: small molecules displaying P-glycoprotein inhibition 78
Predictive models, based on classification algorithms, for compounds potentially active as mitochondrial ATP-sensitive potassium channel openers 75
miRNA Modulation and Antitumor Activity by the Extra-Virgin Olive Oil Polyphenol Oleacein in Human Melanoma Cells 67
The endocannabinoid system dual-target ligand N-cycloheptyl-1,2-dihydro-5-bromo-1-(4-fluorobenzyl)-6-methyl-2-oxo-pyridine-3-carboxamide improves disease severity in a mouse model of multiple sclerosis 65
Oleocanthalic acid from extra-virgin olive oil: Analysis, preparative isolation and radical scavenging activity 65
Pharmacodynamic hybrids with insulin secretagogue and NO-Donor activity 61
NO-sartans: new class of potential cardiovascular drugs 57
Synthesis and Biological Evaluation of 2'-Oxo-2,3-dihydro-3'H-spiro[chromene-4,5'-[1,3]oxazolidin]3'il]acetic Acid Derivatives as Aldose reductase Inhibitors 57
PSNCBAM-1 analogs: Structural evolutions and allosteric properties at cannabinoid CB1 receptor 55
Antioxidant and neuroprotective activity of extra virgin olive oil extracts obtained from quercetano cultivar trees grown in different areas of the tuscany region (Italy) 55
A NOVEL NITRIC OXIDE RELEASING ANTI-DIABETIC DUAL DRUG: FROM THE DESIGN TO THE CHARACTERIZATION OF THE PHARMACOLOGICAL PROFILE 54
Spiro-benzopyran structure: a new scaffold for cardioprotection 53
Immunomodulatory activity of electrospun polyhydroxyalkanoate fiber scaffolds incorporating olive leaf extract 53
Nitric Oxide Releasing and Hypoglycaemic Properties of a Glibenclamde-Related Pharmacodynamic Hybrid 52
Variously substituted 2-oxopyridine derivatives: Extending the structure-activity relationships for allosteric modulation of the cannabinoid CB2 receptor 52
Synthesis and biological evaluation of sulindac derivatives as potential anticancer agents 51
Synthesis and pharmacological activity of new nitric-oxide-donating antihypertensive drugs (NO-Sartans) 51
alpha-Naphtylaminopropan-2-ol derivatives as BACE1 inhibitors 49
The Extra Virgin Olive Oil Polyphenol Oleocanthal Exerts Antifibrotic Effects in the Liver 49
Phenolic Compounds in Prevention and Treatment of Skin Cancers: a review 48
BACE-1 inhibitory activities of new substituted diphenyl-methylenyl-piperazines 43
Content Variations in Oleocanthalic Acid and Other Phenolic Compounds in Extra-Virgin Olive Oil during Storage 42
Synthesis and biological evaluation of arylmethyloxy and heteroarylmethyloxy derivates as potent P-gp modulating agents 40
NOVEL DIARYL UREA DERIVATIVES AS CANNABINOID TYPE 1 RECEPTOR ALLOSTERIC MODULATORS 40
NO-sartans: new class of potential cardiovascular drugs 38
Electrospun Poly(3-Hydroxybutyrate-Co-3-Hydroxyvalerate)/Olive Leaf Extract Fiber Mesh as Prospective Bio-Based Scaffold for Wound Healing 36
"Soft Drugs" Based on Cannabinoid Receptor Ligands as Potential Local Analgesic and Antiglaucoma Agents 35
Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (m TAAR1) Agonists 35
New pharmacodynamic hybrids endowed of insuline secretagogue and NO-donor activities 33
IDENTIFICATION OF NEW PSNCBAM-1 DERIVATIVES AS CB1 RECEPTOR ALLOSTERIC MODULATORS 33
Synthesis and biological evaluation of new compounds as cannabinoid receptor type 1 allosteric modulators 33
Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease 27
Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1H)-One Scaffold 21
Enhanced Nutraceutical Properties of Extra Virgin Olive Oil Extract by Olive Leaf Enrichment 19
The phenolic compounds tyrosol and hydroxytyrosol counteract liver fibrogenesis via the transcriptional modulation of NADPH oxidases and oxidative stress-related miRNAs 17
Olive Mill Wastewater as Source of Polyphenols with Nutraceutical Properties 11
Insights into the Antioxidant/Antiradical Effects and In Vitro Intestinal Permeation of Oleocanthal and Its Metabolites Tyrosol and Oleocanthalic Acid 7
1-Acetoxypinoresinol, a Lignan from Olives: Insight into Its Characterization, Identification, and Nutraceutical Properties 4
Dietary Bioactive Compounds: Implications for Oxidative Stress and Inflammation 4
Totale 8.670
Categoria #
all - tutte 22.767
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 22.767


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.696 193 73 321 94 124 182 155 129 139 113 135 38
2020/2021911 60 42 79 68 69 49 88 73 130 81 49 123
2021/20221.102 32 138 37 58 158 144 46 52 31 21 68 317
2022/20231.477 180 201 127 120 171 182 6 103 255 8 79 45
2023/2024915 97 110 116 45 142 144 62 14 18 16 50 101
2024/202513 13 0 0 0 0 0 0 0 0 0 0 0
Totale 8.670