ORLANDINI, ELISABETTA
 Distribuzione geografica
Continente #
NA - Nord America 13.199
AS - Asia 6.931
EU - Europa 5.446
SA - Sud America 929
AF - Africa 236
OC - Oceania 17
Continente sconosciuto - Info sul continente non disponibili 3
Totale 26.761
Nazione #
US - Stati Uniti d'America 12.790
SG - Singapore 2.147
CN - Cina 1.971
IT - Italia 1.819
HK - Hong Kong 1.005
SE - Svezia 876
BR - Brasile 759
DE - Germania 701
VN - Vietnam 474
BG - Bulgaria 425
FR - Francia 361
GB - Regno Unito 342
TR - Turchia 323
CA - Canada 304
FI - Finlandia 241
IN - India 225
JP - Giappone 192
RU - Federazione Russa 190
KR - Corea 180
UA - Ucraina 175
BD - Bangladesh 80
SN - Senegal 60
IQ - Iraq 58
CH - Svizzera 55
AR - Argentina 51
MX - Messico 43
BE - Belgio 40
ID - Indonesia 36
NL - Olanda 36
PK - Pakistan 35
SA - Arabia Saudita 33
AT - Austria 31
PL - Polonia 31
ZA - Sudafrica 30
VE - Venezuela 28
CI - Costa d'Avorio 27
ES - Italia 27
MA - Marocco 24
NG - Nigeria 22
CO - Colombia 19
EC - Ecuador 18
CZ - Repubblica Ceca 17
KE - Kenya 17
PE - Perù 16
GR - Grecia 14
AE - Emirati Arabi Uniti 13
UY - Uruguay 13
UZ - Uzbekistan 13
AU - Australia 12
JM - Giamaica 12
MY - Malesia 12
TH - Thailandia 12
TW - Taiwan 12
EG - Egitto 10
IR - Iran 10
JO - Giordania 10
TT - Trinidad e Tobago 10
CL - Cile 9
DZ - Algeria 9
IE - Irlanda 9
IL - Israele 9
LT - Lituania 9
PH - Filippine 9
TN - Tunisia 9
DK - Danimarca 8
OM - Oman 8
PA - Panama 8
PS - Palestinian Territory 8
PY - Paraguay 8
AZ - Azerbaigian 7
BO - Bolivia 7
DO - Repubblica Dominicana 7
KZ - Kazakistan 7
NP - Nepal 7
BB - Barbados 6
ET - Etiopia 6
RO - Romania 6
BJ - Benin 5
BY - Bielorussia 5
NZ - Nuova Zelanda 5
SY - Repubblica araba siriana 5
AL - Albania 4
BH - Bahrain 4
EE - Estonia 4
HR - Croazia 4
HU - Ungheria 4
KG - Kirghizistan 4
LB - Libano 4
RS - Serbia 4
AO - Angola 3
BN - Brunei Darussalam 3
CR - Costa Rica 3
GT - Guatemala 3
HN - Honduras 3
KH - Cambogia 3
NI - Nicaragua 3
QA - Qatar 3
AM - Armenia 2
EU - Europa 2
GA - Gabon 2
Totale 26.725
Città #
Ashburn 1.291
Singapore 1.283
Woodbridge 1.279
Ann Arbor 1.097
Hong Kong 991
Chandler 782
Houston 773
Santa Clara 760
Fairfield 732
San Jose 717
Dallas 531
Shanghai 428
Sofia 423
Serra 409
Beijing 384
Milan 356
New York 316
Seattle 310
Wilmington 281
Hefei 243
Cambridge 241
Ottawa 230
Izmir 214
Boardman 206
Jacksonville 206
Princeton 204
Los Angeles 203
Seoul 168
Lawrence 163
Tokyo 158
Medford 150
Lauterbourg 149
Council Bluffs 133
Nanjing 130
Ho Chi Minh City 126
Des Moines 124
Florence 104
London 103
Dearborn 89
Istanbul 83
Frankfurt am Main 77
Dong Ket 72
Hanoi 67
Pisa 67
Buffalo 63
Helsinki 63
Redwood City 63
Rome 63
São Paulo 62
Dakar 60
Redondo Beach 59
Munich 58
Nanchang 55
Bremen 53
Bern 51
Columbus 49
Alessandria 46
The Dalles 44
Marseille 42
San Diego 40
Brussels 38
Pune 37
Orem 35
Kunming 34
Rio de Janeiro 33
Boulder 32
Chicago 32
Lancaster 32
Ogden 31
Jüchen 29
Chennai 28
Nürnberg 28
Abidjan 27
Changsha 26
Gif-sur-Yvette 25
Norwalk 25
Bures-sur-Yvette 24
Livorno 24
Vienna 24
Baghdad 23
Fuzhou 23
Hebei 23
Phoenix 23
Shenyang 23
Belo Horizonte 22
Stockholm 22
Toronto 22
Turku 22
Dhaka 21
Jakarta 21
Hangzhou 20
Auburn Hills 19
Brooklyn 19
Tianjin 19
Warsaw 19
Atlanta 18
Brasília 18
Jiaxing 18
Lagos 18
Nairobi 17
Totale 18.718
Nome #
Application of PROTAC strategy to TTR-Aβ protein-protein interaction for the development of Alzheimer’s disease drugs 364
N-(aroyl)-N-(arylmethyloxy)-α-alanines: selective inhibitors of aldose reductase 253
Focus on Human Monoamine Transporter Selectivity. New Human DAT and NET Models, Experimental Validation, and SERT Affinity Exploration 235
Targeting Different Transthyretin Binding Sites with Unusual Natural Compounds 233
SYNTHESIS AND EVALUATION OF THE PHARMACOLOGICAL ACTIVITY OF RIGID ANALOGUES OF SYMPATHOMIMETIC DERIVED FROM BICYCLO[2.2.1]HEPTANE 223
Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies 222
Synthesis and investigation of polyhydroxylated pyrrolidine derivatives as novel chemotypes showing dual activity as glucosidase and aldose reductase inhibitors 220
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization 214
Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators 211
Synthesis and antimicrobial properties of new cepham and penam derivatives with the carboxylic group in the "wrong" ß-configuration 208
Matrix metalloproteinase-12 inhibitors: synthesis, structure-activity relationships and intestinal absorption of novel sugar-based biphenylsulfonamide carboxylates 206
Enantiopure 3-(arylmethylidene)aminoxy-2-methylpropionic acids: synthesis and antiinflammatory properties 202
INHIBITORS OF ZINC PROTEASES THIOARYL SUBSTITUTED AND THEIR USE 198
D3 dopamine receptor subtype: which binding modes for such different ligands?, 198
Synthesis and antimicrobial properties of substituted 3-aminoxy-(E)-2-methoxyiminopropionyl penicillins and cephalosporins 197
Resveratrol-like Compounds as SIRT1 Activators 195
Synthesis and dopaminergic properties of the two enantiomers of 3-(3,4-dimethylphenyl)-1-propylpiperidine, a potent and selective dopamine D4 receptor ligand 195
Copper mediated amyloid-β binding to Transthyretin 195
Synthesis and cycloxygenase inhibitory properties of new naphthalene-methylsulfonamido, naphthalene-methylsulfonyl and tetrahydronaphthalen-methylsulfonamido compounds 195
Novel Transthyretin Amyloid Fibril Formation Inhibitors: Synthesis, Biological Evaluation, and X-Ray Structural Analysis 192
Design, Synthesis, Biological Evaluation, and NMR Studies of a New Series of Arylsulfones As Selective and Potent Matrix Metalloproteinase-12 Inhibitors 192
Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors 191
Age-related macular degeneration: Current knowledge of zinc metalloproteinases involvement 191
Antioxidant quercetin 3-O-glycosylated plant flavonols contribute to Transthyretin stabilization 188
SYNTHESIS, ANTIINFLAMMATORY ACTIVITY AND MOLECULAR-ORBITAL STUDIES OF A SERIES OF BENZYLIDENEAMINOXYPROPIONIC ACIDS SUBSTITUTED ON THE PHENYL RING 188
N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity 188
D3 dopamine receptor subtype: which binding modes for such different ligands? 187
MOLECULAR DESIGN, SYNTHESIS, AND ANTIINFLAMMATORY ACTIVITY OF A SERIES OF BETA-AMINOXYPROPIONIC ACIDS 187
A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer 187
Conformationally restrained ß-blocking oxime ethers. 2. Synthesis and ß-adrenergic properties of diastereoisomeric anti and syn 2-(5’-(3’-aryl-substituted)isoxazolidinyl)-N-alkylethanolamines 186
SYNTHESIS AND EVALUATION OF THE PHARMACOLOGICAL ACTIVITY OF RIGID ANALOGS OF SYMPATHOMIMETIC CATECHOLAMINES DERIVED FROM BICYCLO[2.2.1]HEPTANE 185
Synthesis of New Classes of MMPs Sugars-Based Inhibitors 184
Synthetic MMP Inhibitors: Slow-Binding Behaviour of Enantioselective N-O-Sulfonamido Based Inhibitors Directed to Specific Matrixins 183
Synthesis and 5-HT2A, 5-HT1Aand a1-Binding Affinities of 2-[2- Hydroxy-3-(pyridin-3-yl-methyl)amino]-, 2-[2-Hydroxy-3-(2- pyridin-2-yl-ethyl)amino]- and 2-[2-Hydroxy-3-(4-N-methylpiperazin- 1-yl)-amino]propoxybenzaldehyde-O-(substituted) Benzyl Oximes 182
Selective Arylsulfonamide Inhibitors of ADAM-17: Hit Optimization and Activity in Ovarian Cancer Cell Models 182
Design, synthesis and biological evaluation of bifunctional inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP) 182
Design of transthyretin amyloidosis inhibitors: A docking and virtual screening approach 179
Synthesis and in-vitro antitumour activity of new naphthyridine derivatives on human pancreatic cancer cells 179
N-O-Isopropyl Sulfonamido-Based Hydroxamates: Design, Synthesis and Biological Evaluation of Selective Matrix Metalloproteinase-13 Inhibitors as Potential Therapeutic Agents for Osteoarthritis 178
Arylsulfonamide inhibitors of aggrecanases as potential therapeutic agents for osteoarthritis: Synthesis and biological evaluation. 177
(E)-[2-(4-Methylsulphonylphenyl)-1-cyclopentenyl-1-methyliden]-(arylmethyloxy)amines. Methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: synthesis and biological properties 177
Potent Arylsulfonamide Inhibitors of Tumor Necrosis Factor-a Converting Enzyme Able to Reduce Activated Leukocyte Cell Adhesion Molecule Shedding in Cancer Cell Models 177
Synthetic analogs of xanthohumol for use in the prevention and​/or treatment of tumors 177
Exploring the binding of quercetin-3-O-metabolites with transthyretin 177
Synthesis and antimicrobial activity of 7ß-(S) and 7ß-(R)-3-(methyleneaminoxy)-2-methylpropionamido substituted cephalosporanic acid derivatives 175
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2) 175
Different Binding Modes of Structurally Diverse Ligands for Human D3DAR 175
4-ARYLPIPERIDINE DERIVATIVES AND USE THEREOF FOR PREPARING A MEDICAMENT FOR THE TREATMENT OF CNS DISEASE 175
Synthesis and adrenergic ß-blocking activity of (oxypropanolamino)-substituted [(benzylideneamino)oxy]propanolamines 175
Conformationally restrained analogues of sympathomimetic catecholamines: Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro[naphthalen-1(2H)-2′,5′- morpholines] 174
1-(1-pirril)-3- ammino-2-propanoli N-sostituiti: sintesi e proprietà ß-adrenergiche 173
Synthesis and aldose reductase inhibitory activity of N-(arylsulfonyl)- and N-(aroyl)-N-(arylmethyloxy)glycines 173
Spiropiperidine strutturalmente correlate alle catecolamine. Sintesi ed attività recettoriale a- e ß-adrenergica 172
A new development of matrix metalloproteinase inhibitors: twin hydroxamic acids as potent inhibitors of MMPs 172
WILSON & GISVOLD CHIMICA FARMACEUTICA (Capitolo 13) 172
Aryl-sulphonamidic dimers as metalloproteases inhibitors 170
Arylsulfonamide derivatives as metalloproteases inhibitors and their preparation, pharmaceutical compositions and use in the treatment of degenerative disorders 168
Human transthyretin (TTR) complexed with (S)-3-(9H-fluoren-9-ylideneaminooxy)-2-methylpropanoic acid (inhibitor 16) 168
New N-n-propyl-substituted 3-Aryl and 3-Cyclohexyl piperidines as partial agonists at the D4 dopamine receptor 167
Sintesi e proprietà beta-adrenergiche di [(benzilideneammino)ossi] propanolammine orto-ossipropanolammine sostituite chirali, 165
Carbonic anhydrase inhibitors and epilepsy: State of the art and future perspectives 165
Compounds with a benzo [a]carbazole structure for use in the prevention and/or treatment of infectious diseases 164
Compounds having aryl-sulphonamidic structure useful as metalloproteases inhibitors 164
TTR fibril formation inhibitors: is there a SAR? 164
Role of the benzylic hydroxyl group of adrenergic catecholamines in eliciting a-adrenergic activity. Synthesis and a1- and a2-adrenergic activity of 3-phenyl-3-piperidinols and of their desoxy analogs 164
Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid (inhibitor 15) 164
Conformational effects on the activity of drugs. Synthesis and adrenergic properties of 2-methyl-substituted 3-(3,4- dihydroxyphenyl)-3-piperidinols 163
Synthesis and antiangiogenic activity study of new hop chalcone Xanthohumol analogues 163
Synthesis and Evaluation of Monoaryl Derivatives as Transthyretin Fibril Formation Inhibitors 162
Aryl-substituted methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: effects of some structural modifications on their biological properties 160
2-(phenylsulphonamido)-pyrazole derivatives as carbonic anhydrase inhibitors 158
Synthesis and adrenergic beta-blocking activity of ortho-, meta- and para-oxypropanolamino-substituted [(benzylideneamino)oxy]propanolamines. 157
Transthyretin amyloidosis: a computational approach toward the design of new inhibitors 156
(E)-(ARYLMETHYLENEAMINOXY)ACETAMIDES AS ANALOGS OF NEUROLEPTIC BENZAMIDES - SYNTHESIS AND D-2-DOPAMINERGIC BINDING-AFFINITY 156
Oxy-imino saccharidic derivatives as a new structural class of aldose reductase inhibitors endowed with anti-oxidant activity 156
Omega-3 PUFAs as a Dietary Supplement in Senile Systemic Amyloidosis 155
Powerful twin carboxylic inhibitors for MMP homodimerization 155
N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP 154
New Hybrid Compounds Incorporating Natural Products as Multifunctional Agents against Alzheimer's Disease 153
SYNTHESIS, PLATELET ANTI-AGGREGATING ACTIVITY AND ANTIINFLAMMATORY ACTIVITY OF A SERIES OF BETA-AMINOXYPROPIONIC ACIDS 152
Synthesis and antiviral properties of 9-[(2-methyleneaminoxyethoxy)methyl]guanine derivatives as novel acyclovir analogues 152
A new crystal form of human transthyretin obtained with a curcumin derived ligand 152
Design, synthesis, biological evaluation and NMR studies of a new series of arylsulfones as selective and potent MMP-12 inhibitors 151
Comparison of helical scan and standard rotation methods in single-crystal X-ray data collection strategies 151
Synthesis and prostaglandin synthase inhibitory activity of new aromatic O-alkyloxime ethers substituted with methylsulfonamido or methylsulfonyl groups on their aliphatic portion 150
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma 150
Structural Insights on Carbonic Anhydrase Inhibitory Action, Isoform Selectivity, and Potency of Sulfonamides and Coumarins Incorporating Arylsulfonylureido Groups 150
Synthesis and aldose reductase inhibitory activity of some N-(aroyl)-N-(arylalkyloxy)-glycines and -beta-alanines 149
X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors 149
Pomegranate: A Source of Multifunctional Bioactive Compounds Potentially Beneficial in Alzheimer’s Disease 148
Human transthyretin (TTR) complexed with (E)-3-(2-methoxybenzylideneaminooxy)propanoic acid (inhibitor 13) 148
Nature-Inspired O-Benzyl Oxime-Based Derivatives as New Dual-Acting Agents Targeting Aldose Reductase and Oxidative Stress 147
Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR) 147
Sintesi ed attività adrenergica di analoghi ciclici dell’1-(2,5-dimetossifenil)-2-amminoetanolo 146
1-(PHENYLSULPHONAMIDO)-PYRAZOLE DERIVATIVES AS CARBONIC ANHYDRASE INHIBITORS. 146
SYNTHESIS, ANTIINFLAMMATORY ACTIVITY AND PLATELET ANTIAGGREGATING ACTIVITY OF A NEW SERIES OF BETA-AMINOXYPROPIONIC ACIDS 145
Synthesis and COX2 inhibitory properties of N-Phenyl-and N-benzyl-substituted amides of 2-(4-methylsulfonylphenyl)cyclopent-1-ene-1-carboxylic acid and of their pyrazole, thiophene, and isoxazole analogs 145
NMR STUDIES OF A NEW POTENT MMP-12 INHIBITOR: INSIGHT INTO KEY BINDING INTERACTIONS 143
Synthesis and aldose reductase inhibitory activity of new N-(benzyloxy) glycine derivatives 143
Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates 143
Totale 17.649
Categoria #
all - tutte 75.617
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 75.617


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021188 0 0 0 0 0 0 0 0 0 0 0 188
2021/20222.027 51 219 47 98 351 262 72 98 63 47 129 590
2022/20232.572 341 355 197 241 258 342 21 172 431 6 153 55
2023/20241.739 222 176 183 89 276 359 91 38 27 39 73 166
2024/20255.608 22 210 121 299 569 472 547 337 525 712 580 1.214
2025/20266.370 518 856 734 540 566 557 1.007 284 356 584 247 121
Totale 27.188