CINECA IRIS Institutional Research Information System

ORLANDINI, ELISABETTA
 Distribuzione geografica
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Continente #
NA - Nord America 11.924
AS - Asia 6.027
EU - Europa 5.094
SA - Sud America 875
AF - Africa 204
OC - Oceania 15
Continente sconosciuto - Info sul continente non disponibili 3
Totale 24.142
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Nazione #
US - Stati Uniti d'America 11.553
CN - Cina 1.867
SG - Singapore 1.821
IT - Italia 1.748
HK - Hong Kong 971
SE - Svezia 875
BR - Brasile 724
DE - Germania 681
BG - Bulgaria 424
GB - Regno Unito 325
TR - Turchia 315
CA - Canada 283
VN - Vietnam 270
FR - Francia 202
FI - Finlandia 199
IN - India 188
RU - Federazione Russa 185
KR - Corea 178
UA - Ucraina 172
JP - Giappone 86
BD - Bangladesh 69
SN - Senegal 60
CH - Svizzera 52
AR - Argentina 48
IQ - Iraq 46
BE - Belgio 39
MX - Messico 37
AT - Austria 31
PK - Pakistan 31
PL - Polonia 28
ID - Indonesia 27
SA - Arabia Saudita 27
CI - Costa d'Avorio 26
ZA - Sudafrica 26
VE - Venezuela 25
NL - Olanda 24
NG - Nigeria 22
ES - Italia 21
MA - Marocco 20
EC - Ecuador 17
CZ - Repubblica Ceca 16
CO - Colombia 14
GR - Grecia 14
PE - Perù 14
KE - Kenya 12
AE - Emirati Arabi Uniti 11
UY - Uruguay 11
UZ - Uzbekistan 11
AU - Australia 10
IR - Iran 10
JM - Giamaica 10
JO - Giordania 10
TW - Taiwan 10
CL - Cile 9
IL - Israele 9
LT - Lituania 9
TT - Trinidad e Tobago 9
DK - Danimarca 8
IE - Irlanda 8
MY - Malesia 8
PY - Paraguay 8
DO - Repubblica Dominicana 7
OM - Oman 7
PA - Panama 7
PS - Palestinian Territory 7
AZ - Azerbaigian 6
EG - Egitto 6
KZ - Kazakistan 6
RO - Romania 6
BB - Barbados 5
BJ - Benin 5
ET - Etiopia 5
NZ - Nuova Zelanda 5
BO - Bolivia 4
DZ - Algeria 4
EE - Estonia 4
HR - Croazia 4
KG - Kirghizistan 4
NP - Nepal 4
PH - Filippine 4
AL - Albania 3
AO - Angola 3
BN - Brunei Darussalam 3
CR - Costa Rica 3
HN - Honduras 3
HU - Ungheria 3
LB - Libano 3
QA - Qatar 3
RS - Serbia 3
SY - Repubblica araba siriana 3
BH - Bahrain 2
BY - Bielorussia 2
EU - Europa 2
GA - Gabon 2
KW - Kuwait 2
LK - Sri Lanka 2
NI - Nicaragua 2
PT - Portogallo 2
SC - Seychelles 2
SK - Slovacchia (Repubblica Slovacca) 2
Totale 24.114
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Città #
Woodbridge 1.279
Ashburn 1.173
Ann Arbor 1.097
Singapore 1.032
Hong Kong 965
Chandler 782
Houston 770
Santa Clara 749
Fairfield 732
Dallas 519
Shanghai 427
Sofia 423
Serra 409
Beijing 369
Milan 349
New York 309
Seattle 309
Wilmington 280
Hefei 243
Cambridge 239
Ottawa 230
Izmir 214
Boardman 206
Jacksonville 205
Princeton 204
Los Angeles 189
Seoul 167
Lawrence 163
Medford 150
Nanjing 130
Des Moines 123
Florence 103
London 103
Dearborn 89
Istanbul 82
Dong Ket 72
Frankfurt am Main 66
Redwood City 63
Pisa 62
Buffalo 61
Dakar 60
Redondo Beach 59
Munich 58
São Paulo 57
Tokyo 57
Rome 56
Nanchang 55
Council Bluffs 54
Bremen 53
Bern 51
Ho Chi Minh City 49
Alessandria 46
The Dalles 44
Marseille 42
Columbus 41
San Diego 39
Brussels 37
Pune 37
Kunming 34
Boulder 32
Lancaster 32
Rio de Janeiro 32
Ogden 31
Jüchen 29
Nürnberg 28
Abidjan 26
Changsha 26
Chicago 26
Gif-sur-Yvette 25
Norwalk 25
Bures-sur-Yvette 24
Livorno 24
Vienna 24
Hanoi 23
Hebei 23
Helsinki 23
Shenyang 23
Belo Horizonte 22
Fuzhou 22
Stockholm 22
Turku 22
Phoenix 21
Dhaka 20
Toronto 20
Auburn Hills 19
Brooklyn 19
Hangzhou 19
Tianjin 19
Warsaw 19
Baghdad 18
Jakarta 18
Jiaxing 18
Lagos 18
Pessac 17
Trieste 17
Brasília 16
Chennai 16
Paris 16
San Francisco 16
College Station 15
Totale 16.971
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Nome #
Application of PROTAC strategy to TTR-Aβ protein-protein interaction for the development of Alzheimer’s disease drugs 298
N-(aroyl)-N-(arylmethyloxy)-α-alanines: selective inhibitors of aldose reductase 221
Targeting Different Transthyretin Binding Sites with Unusual Natural Compounds 211
SYNTHESIS AND EVALUATION OF THE PHARMACOLOGICAL ACTIVITY OF RIGID ANALOGUES OF SYMPATHOMIMETIC DERIVED FROM BICYCLO[2.2.1]HEPTANE 210
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization 205
Focus on Human Monoamine Transporter Selectivity. New Human DAT and NET Models, Experimental Validation, and SERT Affinity Exploration 202
Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies 198
Synthesis and investigation of polyhydroxylated pyrrolidine derivatives as novel chemotypes showing dual activity as glucosidase and aldose reductase inhibitors 198
Enantiopure 3-(arylmethylidene)aminoxy-2-methylpropionic acids: synthesis and antiinflammatory properties 191
D3 dopamine receptor subtype: which binding modes for such different ligands?, 190
INHIBITORS OF ZINC PROTEASES THIOARYL SUBSTITUTED AND THEIR USE 186
Synthesis and antimicrobial properties of substituted 3-aminoxy-(E)-2-methoxyiminopropionyl penicillins and cephalosporins 184
Synthesis and dopaminergic properties of the two enantiomers of 3-(3,4-dimethylphenyl)-1-propylpiperidine, a potent and selective dopamine D4 receptor ligand 183
Copper mediated amyloid-β binding to Transthyretin 183
Matrix metalloproteinase-12 inhibitors: synthesis, structure-activity relationships and intestinal absorption of novel sugar-based biphenylsulfonamide carboxylates 183
Synthesis and cycloxygenase inhibitory properties of new naphthalene-methylsulfonamido, naphthalene-methylsulfonyl and tetrahydronaphthalen-methylsulfonamido compounds 183
SYNTHESIS, ANTIINFLAMMATORY ACTIVITY AND MOLECULAR-ORBITAL STUDIES OF A SERIES OF BENZYLIDENEAMINOXYPROPIONIC ACIDS SUBSTITUTED ON THE PHENYL RING 181
Synthesis and antimicrobial properties of new cepham and penam derivatives with the carboxylic group in the "wrong" ß-configuration 180
D3 dopamine receptor subtype: which binding modes for such different ligands? 180
N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity 178
Synthesis and 5-HT2A, 5-HT1Aand a1-Binding Affinities of 2-[2- Hydroxy-3-(pyridin-3-yl-methyl)amino]-, 2-[2-Hydroxy-3-(2- pyridin-2-yl-ethyl)amino]- and 2-[2-Hydroxy-3-(4-N-methylpiperazin- 1-yl)-amino]propoxybenzaldehyde-O-(substituted) Benzyl Oximes 175
Novel Transthyretin Amyloid Fibril Formation Inhibitors: Synthesis, Biological Evaluation, and X-Ray Structural Analysis 175
Conformationally restrained ß-blocking oxime ethers. 2. Synthesis and ß-adrenergic properties of diastereoisomeric anti and syn 2-(5’-(3’-aryl-substituted)isoxazolidinyl)-N-alkylethanolamines 174
MOLECULAR DESIGN, SYNTHESIS, AND ANTIINFLAMMATORY ACTIVITY OF A SERIES OF BETA-AMINOXYPROPIONIC ACIDS 174
Age-related macular degeneration: Current knowledge of zinc metalloproteinases involvement 174
Design, Synthesis, Biological Evaluation, and NMR Studies of a New Series of Arylsulfones As Selective and Potent Matrix Metalloproteinase-12 Inhibitors 173
Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators 172
Synthesis and in-vitro antitumour activity of new naphthyridine derivatives on human pancreatic cancer cells 171
Selective Arylsulfonamide Inhibitors of ADAM-17: Hit Optimization and Activity in Ovarian Cancer Cell Models 170
A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer 170
Synthesis and antimicrobial activity of 7ß-(S) and 7ß-(R)-3-(methyleneaminoxy)-2-methylpropionamido substituted cephalosporanic acid derivatives 169
Synthetic MMP Inhibitors: Slow-Binding Behaviour of Enantioselective N-O-Sulfonamido Based Inhibitors Directed to Specific Matrixins 168
N-O-Isopropyl Sulfonamido-Based Hydroxamates: Design, Synthesis and Biological Evaluation of Selective Matrix Metalloproteinase-13 Inhibitors as Potential Therapeutic Agents for Osteoarthritis 167
Synthesis and adrenergic ß-blocking activity of (oxypropanolamino)-substituted [(benzylideneamino)oxy]propanolamines 167
Arylsulfonamide inhibitors of aggrecanases as potential therapeutic agents for osteoarthritis: Synthesis and biological evaluation. 166
Different Binding Modes of Structurally Diverse Ligands for Human D3DAR 165
Exploring the binding of quercetin-3-O-metabolites with transthyretin 165
Conformationally restrained analogues of sympathomimetic catecholamines: Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro[naphthalen-1(2H)-2′,5′- morpholines] 164
A new development of matrix metalloproteinase inhibitors: twin hydroxamic acids as potent inhibitors of MMPs 164
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2) 164
Synthesis and aldose reductase inhibitory activity of N-(arylsulfonyl)- and N-(aroyl)-N-(arylmethyloxy)glycines 163
Potent Arylsulfonamide Inhibitors of Tumor Necrosis Factor-a Converting Enzyme Able to Reduce Activated Leukocyte Cell Adhesion Molecule Shedding in Cancer Cell Models 163
Design, synthesis and biological evaluation of bifunctional inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP) 163
Antioxidant quercetin 3-O-glycosylated plant flavonols contribute to Transthyretin stabilization 162
1-(1-pirril)-3- ammino-2-propanoli N-sostituiti: sintesi e proprietà ß-adrenergiche 162
Synthesis of New Classes of MMPs Sugars-Based Inhibitors 162
Synthetic analogs of xanthohumol for use in the prevention and​/or treatment of tumors 162
Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors 162
WILSON & GISVOLD CHIMICA FARMACEUTICA (Capitolo 13) 161
4-ARYLPIPERIDINE DERIVATIVES AND USE THEREOF FOR PREPARING A MEDICAMENT FOR THE TREATMENT OF CNS DISEASE 160
SYNTHESIS AND EVALUATION OF THE PHARMACOLOGICAL ACTIVITY OF RIGID ANALOGS OF SYMPATHOMIMETIC CATECHOLAMINES DERIVED FROM BICYCLO[2.2.1]HEPTANE 159
(E)-[2-(4-Methylsulphonylphenyl)-1-cyclopentenyl-1-methyliden]-(arylmethyloxy)amines. Methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: synthesis and biological properties 159
Aryl-sulphonamidic dimers as metalloproteases inhibitors 158
Design of transthyretin amyloidosis inhibitors: A docking and virtual screening approach 158
Arylsulfonamide derivatives as metalloproteases inhibitors and their preparation, pharmaceutical compositions and use in the treatment of degenerative disorders 158
Human transthyretin (TTR) complexed with (S)-3-(9H-fluoren-9-ylideneaminooxy)-2-methylpropanoic acid (inhibitor 16) 157
TTR fibril formation inhibitors: is there a SAR? 155
Compounds having aryl-sulphonamidic structure useful as metalloproteases inhibitors 154
New N-n-propyl-substituted 3-Aryl and 3-Cyclohexyl piperidines as partial agonists at the D4 dopamine receptor 154
Role of the benzylic hydroxyl group of adrenergic catecholamines in eliciting a-adrenergic activity. Synthesis and a1- and a2-adrenergic activity of 3-phenyl-3-piperidinols and of their desoxy analogs 154
Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid (inhibitor 15) 154
Conformational effects on the activity of drugs. Synthesis and adrenergic properties of 2-methyl-substituted 3-(3,4- dihydroxyphenyl)-3-piperidinols 153
Spiropiperidine strutturalmente correlate alle catecolamine. Sintesi ed attività recettoriale a- e ß-adrenergica 151
N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP 150
Sintesi e proprietà beta-adrenergiche di [(benzilideneammino)ossi] propanolammine orto-ossipropanolammine sostituite chirali, 149
Synthesis and antiangiogenic activity study of new hop chalcone Xanthohumol analogues 149
SYNTHESIS, PLATELET ANTI-AGGREGATING ACTIVITY AND ANTIINFLAMMATORY ACTIVITY OF A SERIES OF BETA-AMINOXYPROPIONIC ACIDS 146
Oxy-imino saccharidic derivatives as a new structural class of aldose reductase inhibitors endowed with anti-oxidant activity 146
Synthesis and adrenergic beta-blocking activity of ortho-, meta- and para-oxypropanolamino-substituted [(benzylideneamino)oxy]propanolamines. 145
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma 145
Synthesis and prostaglandin synthase inhibitory activity of new aromatic O-alkyloxime ethers substituted with methylsulfonamido or methylsulfonyl groups on their aliphatic portion 144
Comparison of helical scan and standard rotation methods in single-crystal X-ray data collection strategies 144
Powerful twin carboxylic inhibitors for MMP homodimerization 143
A new crystal form of human transthyretin obtained with a curcumin derived ligand 141
Aryl-substituted methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: effects of some structural modifications on their biological properties 140
(E)-(ARYLMETHYLENEAMINOXY)ACETAMIDES AS ANALOGS OF NEUROLEPTIC BENZAMIDES - SYNTHESIS AND D-2-DOPAMINERGIC BINDING-AFFINITY 140
Structural Insights on Carbonic Anhydrase Inhibitory Action, Isoform Selectivity, and Potency of Sulfonamides and Coumarins Incorporating Arylsulfonylureido Groups 140
Resveratrol-like Compounds as SIRT1 Activators 139
X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors 139
Transthyretin amyloidosis: a computational approach toward the design of new inhibitors 138
Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates 138
Design, synthesis, biological evaluation and NMR studies of a new series of arylsulfones as selective and potent MMP-12 inhibitors 138
Synthesis and antiviral properties of 9-[(2-methyleneaminoxyethoxy)methyl]guanine derivatives as novel acyclovir analogues 137
1-(PHENYLSULPHONAMIDO)-PYRAZOLE DERIVATIVES AS CARBONIC ANHYDRASE INHIBITORS. 136
A new small molecule, D2 dopamine receptor agonist, as an allosteric modulator of A2A adenosine receptor signalling 135
2-(phenylsulphonamido)-pyrazole derivatives as carbonic anhydrase inhibitors 135
Synthesis and aldose reductase inhibitory activity of some N-(aroyl)-N-(arylalkyloxy)-glycines and -beta-alanines 134
Compounds with a benzo [a]carbazole structure for use in the prevention and/or treatment of infectious diseases 133
Synthesis and COX2 inhibitory properties of N-Phenyl-and N-benzyl-substituted amides of 2-(4-methylsulfonylphenyl)cyclopent-1-ene-1-carboxylic acid and of their pyrazole, thiophene, and isoxazole analogs 133
Human transthyretin (TTR) complexed with (E)-3-(2-methoxybenzylideneaminooxy)propanoic acid (inhibitor 13) 133
SYNTHESIS, ANTIINFLAMMATORY ACTIVITY AND PLATELET ANTIAGGREGATING ACTIVITY OF A NEW SERIES OF BETA-AMINOXYPROPIONIC ACIDS 132
Synthesis and Preliminary Evaluation in Tumor Bearing Mice of New 18F‑Labeled Arylsulfone Matrix Metalloproteinase Inhibitors as Tracers for Positron Emission Tomography 132
Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR) 132
Synthesis, Inhibitory Activity Towards Human Leukocyte Elastase and Molecular Modelling Studies of Carbamoyl-4-methyleneaminoxyazetidinones 131
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW 7BETA-(BENZO[A]DIHYDROCARBAZOLYLOXYACETYL)-SUBSTITUTED CEPHALOSPORINS 131
Novel tacrine–benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer’s Disease 131
Omega-3 PUFAs as a Dietary Supplement in Senile Systemic Amyloidosis 130
Inibitori di zinco proteinasi tioaril sostituiti e loro usi 130
Human Transthyretin (TTR) complexed with(E)-3-(2-(trifluoromethyl)benzylideneaminooxy)propanoic acid (inhibitor 11) 130
N-n-propyl-substituted 3-(dimethylphenyl)piperidines display novel discriminative properties between dopamine receptor subtypes: synthesis and receptor binding studies 129
Totale 16.074
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Categoria #
all - tutte 67.853
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 67.853
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021899 0 0 0 0 0 112 115 159 134 110 81 188
2021/20222.027 51 219 47 98 351 262 72 98 63 47 129 590
2022/20232.572 341 355 197 241 258 342 21 172 431 6 153 55
2023/20241.739 222 176 183 89 276 359 91 38 27 39 73 166
2024/20255.608 22 210 121 299 569 472 547 337 525 712 580 1.214
2025/20263.747 518 856 734 540 566 533 0 0 0 0 0 0
Totale 24.565