ORLANDINI, ELISABETTA
 Distribuzione geografica
Continente #
NA - Nord America 13.669
AS - Asia 6.948
EU - Europa 5.468
SA - Sud America 944
Continente sconosciuto - Info sul continente non disponibili 430
AF - Africa 236
OC - Oceania 17
Totale 27.712
Nazione #
US - Stati Uniti d'America 13.239
SG - Singapore 2.148
CN - Cina 1.979
IT - Italia 1.828
HK - Hong Kong 1.008
SE - Svezia 882
BR - Brasile 768
DE - Germania 701
VN - Vietnam 474
BG - Bulgaria 425
FR - Francia 363
GB - Regno Unito 342
TR - Turchia 323
CA - Canada 311
FI - Finlandia 241
IN - India 227
JP - Giappone 192
RU - Federazione Russa 190
KR - Corea 182
UA - Ucraina 175
BD - Bangladesh 80
SN - Senegal 60
IQ - Iraq 58
CH - Svizzera 55
AR - Argentina 51
MX - Messico 46
BE - Belgio 40
NL - Olanda 38
ID - Indonesia 36
PK - Pakistan 35
SA - Arabia Saudita 33
AT - Austria 31
PL - Polonia 31
ZA - Sudafrica 30
VE - Venezuela 29
ES - Italia 28
CI - Costa d'Avorio 27
MA - Marocco 24
NG - Nigeria 22
CO - Colombia 19
EC - Ecuador 19
CZ - Repubblica Ceca 17
KE - Kenya 17
PE - Perù 16
GR - Grecia 14
JM - Giamaica 14
UY - Uruguay 14
AE - Emirati Arabi Uniti 13
UZ - Uzbekistan 13
AU - Australia 12
MY - Malesia 12
TH - Thailandia 12
TW - Taiwan 12
CL - Cile 11
TT - Trinidad e Tobago 11
EG - Egitto 10
IR - Iran 10
JO - Giordania 10
PH - Filippine 10
DZ - Algeria 9
IE - Irlanda 9
IL - Israele 9
LT - Lituania 9
TN - Tunisia 9
DK - Danimarca 8
OM - Oman 8
PA - Panama 8
PS - Palestinian Territory 8
PY - Paraguay 8
AZ - Azerbaigian 7
BO - Bolivia 7
DO - Repubblica Dominicana 7
KZ - Kazakistan 7
NP - Nepal 7
BB - Barbados 6
ET - Etiopia 6
RO - Romania 6
BJ - Benin 5
BY - Bielorussia 5
CR - Costa Rica 5
NZ - Nuova Zelanda 5
SY - Repubblica araba siriana 5
AL - Albania 4
BH - Bahrain 4
EE - Estonia 4
HR - Croazia 4
HU - Ungheria 4
KG - Kirghizistan 4
LB - Libano 4
RS - Serbia 4
SV - El Salvador 4
AO - Angola 3
BN - Brunei Darussalam 3
GT - Guatemala 3
HN - Honduras 3
KH - Cambogia 3
NI - Nicaragua 3
PR - Porto Rico 3
QA - Qatar 3
AM - Armenia 2
Totale 27.243
Città #
Ashburn 1.340
Singapore 1.284
Woodbridge 1.279
Ann Arbor 1.097
Hong Kong 994
Chandler 782
Houston 774
Santa Clara 769
Fairfield 732
San Jose 726
Dallas 534
Shanghai 428
Sofia 423
Serra 409
Beijing 390
Milan 356
New York 320
Seattle 310
Wilmington 281
Hefei 243
Cambridge 242
Ottawa 230
Izmir 214
Boardman 209
Los Angeles 207
Jacksonville 206
Princeton 205
Council Bluffs 189
Seoul 168
Lawrence 163
Tokyo 158
Medford 150
Lauterbourg 149
Nanjing 130
Ho Chi Minh City 126
Des Moines 125
Florence 105
London 103
Dearborn 89
Istanbul 83
Frankfurt am Main 77
Dong Ket 72
Pisa 68
Hanoi 67
Rome 64
Buffalo 63
Helsinki 63
Redwood City 63
São Paulo 62
Dakar 60
Redondo Beach 59
Munich 58
Nanchang 55
Bremen 53
Bern 51
Columbus 50
Alessandria 46
The Dalles 46
Marseille 42
San Diego 40
Brussels 38
Pune 37
Chicago 36
Orem 36
Kunming 34
Rio de Janeiro 33
Boulder 32
Lancaster 32
Ogden 31
Jüchen 29
Chennai 28
Nürnberg 28
Abidjan 27
Changsha 26
Gif-sur-Yvette 25
Norwalk 25
Bures-sur-Yvette 24
Livorno 24
Phoenix 24
Toronto 24
Vienna 24
Baghdad 23
Fuzhou 23
Hebei 23
Shenyang 23
Belo Horizonte 22
Brooklyn 22
Stockholm 22
Turku 22
Dhaka 21
Jakarta 21
Atlanta 20
Hangzhou 20
Auburn Hills 19
Brasília 19
Tianjin 19
Warsaw 19
Jiaxing 18
Lagos 18
San Francisco 18
Totale 18.890
Nome #
Resveratrol-like Compounds as SIRT1 Activators 391
Application of PROTAC strategy to TTR-Aβ protein-protein interaction for the development of Alzheimer’s disease drugs 370
N-(aroyl)-N-(arylmethyloxy)-α-alanines: selective inhibitors of aldose reductase 259
Targeting Different Transthyretin Binding Sites with Unusual Natural Compounds 240
Focus on Human Monoamine Transporter Selectivity. New Human DAT and NET Models, Experimental Validation, and SERT Affinity Exploration 239
Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies 226
SYNTHESIS AND EVALUATION OF THE PHARMACOLOGICAL ACTIVITY OF RIGID ANALOGUES OF SYMPATHOMIMETIC DERIVED FROM BICYCLO[2.2.1]HEPTANE 225
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization 223
Synthesis and investigation of polyhydroxylated pyrrolidine derivatives as novel chemotypes showing dual activity as glucosidase and aldose reductase inhibitors 223
Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators 213
Synthesis and antimicrobial properties of new cepham and penam derivatives with the carboxylic group in the "wrong" ß-configuration 209
Matrix metalloproteinase-12 inhibitors: synthesis, structure-activity relationships and intestinal absorption of novel sugar-based biphenylsulfonamide carboxylates 207
Enantiopure 3-(arylmethylidene)aminoxy-2-methylpropionic acids: synthesis and antiinflammatory properties 202
D3 dopamine receptor subtype: which binding modes for such different ligands?, 202
INHIBITORS OF ZINC PROTEASES THIOARYL SUBSTITUTED AND THEIR USE 200
Synthesis and antimicrobial properties of substituted 3-aminoxy-(E)-2-methoxyiminopropionyl penicillins and cephalosporins 197
Synthesis and cycloxygenase inhibitory properties of new naphthalene-methylsulfonamido, naphthalene-methylsulfonyl and tetrahydronaphthalen-methylsulfonamido compounds 197
Copper mediated amyloid-β binding to Transthyretin 196
Synthesis and dopaminergic properties of the two enantiomers of 3-(3,4-dimethylphenyl)-1-propylpiperidine, a potent and selective dopamine D4 receptor ligand 195
Novel Transthyretin Amyloid Fibril Formation Inhibitors: Synthesis, Biological Evaluation, and X-Ray Structural Analysis 195
Age-related macular degeneration: Current knowledge of zinc metalloproteinases involvement 195
Design, Synthesis, Biological Evaluation, and NMR Studies of a New Series of Arylsulfones As Selective and Potent Matrix Metalloproteinase-12 Inhibitors 192
Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors 192
Antioxidant quercetin 3-O-glycosylated plant flavonols contribute to Transthyretin stabilization 191
4-ARYLPIPERIDINE DERIVATIVES AND USE THEREOF FOR PREPARING A MEDICAMENT FOR THE TREATMENT OF CNS DISEASE 191
D3 dopamine receptor subtype: which binding modes for such different ligands? 190
N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity 190
MOLECULAR DESIGN, SYNTHESIS, AND ANTIINFLAMMATORY ACTIVITY OF A SERIES OF BETA-AMINOXYPROPIONIC ACIDS 188
SYNTHESIS, ANTIINFLAMMATORY ACTIVITY AND MOLECULAR-ORBITAL STUDIES OF A SERIES OF BENZYLIDENEAMINOXYPROPIONIC ACIDS SUBSTITUTED ON THE PHENYL RING 188
A new D2 dopamine receptor agonist allosterically modulates A2A adenosine receptor signalling by interacting with the A2A/D2 receptor heteromer 188
Synthetic MMP Inhibitors: Slow-Binding Behaviour of Enantioselective N-O-Sulfonamido Based Inhibitors Directed to Specific Matrixins 187
Conformationally restrained ß-blocking oxime ethers. 2. Synthesis and ß-adrenergic properties of diastereoisomeric anti and syn 2-(5’-(3’-aryl-substituted)isoxazolidinyl)-N-alkylethanolamines 186
SYNTHESIS AND EVALUATION OF THE PHARMACOLOGICAL ACTIVITY OF RIGID ANALOGS OF SYMPATHOMIMETIC CATECHOLAMINES DERIVED FROM BICYCLO[2.2.1]HEPTANE 185
Selective Arylsulfonamide Inhibitors of ADAM-17: Hit Optimization and Activity in Ovarian Cancer Cell Models 185
Synthesis of New Classes of MMPs Sugars-Based Inhibitors 185
Design, synthesis and biological evaluation of bifunctional inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP) 183
Synthesis and 5-HT2A, 5-HT1Aand a1-Binding Affinities of 2-[2- Hydroxy-3-(pyridin-3-yl-methyl)amino]-, 2-[2-Hydroxy-3-(2- pyridin-2-yl-ethyl)amino]- and 2-[2-Hydroxy-3-(4-N-methylpiperazin- 1-yl)-amino]propoxybenzaldehyde-O-(substituted) Benzyl Oximes 182
(E)-[2-(4-Methylsulphonylphenyl)-1-cyclopentenyl-1-methyliden]-(arylmethyloxy)amines. Methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: synthesis and biological properties 181
Design of transthyretin amyloidosis inhibitors: A docking and virtual screening approach 180
Different Binding Modes of Structurally Diverse Ligands for Human D3DAR 180
Potent Arylsulfonamide Inhibitors of Tumor Necrosis Factor-a Converting Enzyme Able to Reduce Activated Leukocyte Cell Adhesion Molecule Shedding in Cancer Cell Models 180
Synthesis and in-vitro antitumour activity of new naphthyridine derivatives on human pancreatic cancer cells 180
Arylsulfonamide inhibitors of aggrecanases as potential therapeutic agents for osteoarthritis: Synthesis and biological evaluation. 179
Exploring the binding of quercetin-3-O-metabolites with transthyretin 179
N-O-Isopropyl Sulfonamido-Based Hydroxamates: Design, Synthesis and Biological Evaluation of Selective Matrix Metalloproteinase-13 Inhibitors as Potential Therapeutic Agents for Osteoarthritis 178
Synthetic analogs of xanthohumol for use in the prevention and​/or treatment of tumors 177
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2) 176
Synthesis and adrenergic ß-blocking activity of (oxypropanolamino)-substituted [(benzylideneamino)oxy]propanolamines 176
Carbonic anhydrase inhibitors and epilepsy: State of the art and future perspectives 176
1-(1-pirril)-3- ammino-2-propanoli N-sostituiti: sintesi e proprietà ß-adrenergiche 175
Synthesis and antimicrobial activity of 7ß-(S) and 7ß-(R)-3-(methyleneaminoxy)-2-methylpropionamido substituted cephalosporanic acid derivatives 175
Conformationally restrained analogues of sympathomimetic catecholamines: Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro[naphthalen-1(2H)-2′,5′- morpholines] 174
Synthesis and aldose reductase inhibitory activity of N-(arylsulfonyl)- and N-(aroyl)-N-(arylmethyloxy)glycines 174
A new development of matrix metalloproteinase inhibitors: twin hydroxamic acids as potent inhibitors of MMPs 173
Spiropiperidine strutturalmente correlate alle catecolamine. Sintesi ed attività recettoriale a- e ß-adrenergica 172
WILSON & GISVOLD CHIMICA FARMACEUTICA (Capitolo 13) 172
Aryl-sulphonamidic dimers as metalloproteases inhibitors 171
Arylsulfonamide derivatives as metalloproteases inhibitors and their preparation, pharmaceutical compositions and use in the treatment of degenerative disorders 171
Human transthyretin (TTR) complexed with (S)-3-(9H-fluoren-9-ylideneaminooxy)-2-methylpropanoic acid (inhibitor 16) 168
Compounds with a benzo [a]carbazole structure for use in the prevention and/or treatment of infectious diseases 167
Synthesis and aldose reductase inhibitory activity of some N-(aroyl)-N-(arylalkyloxy)-glycines and -beta-alanines 167
New N-n-propyl-substituted 3-Aryl and 3-Cyclohexyl piperidines as partial agonists at the D4 dopamine receptor 167
Role of the benzylic hydroxyl group of adrenergic catecholamines in eliciting a-adrenergic activity. Synthesis and a1- and a2-adrenergic activity of 3-phenyl-3-piperidinols and of their desoxy analogs 166
Sintesi e proprietà beta-adrenergiche di [(benzilideneammino)ossi] propanolammine orto-ossipropanolammine sostituite chirali, 165
Compounds having aryl-sulphonamidic structure useful as metalloproteases inhibitors 165
Synthesis and Evaluation of Monoaryl Derivatives as Transthyretin Fibril Formation Inhibitors 164
TTR fibril formation inhibitors: is there a SAR? 164
Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid (inhibitor 15) 164
Synthesis and antiangiogenic activity study of new hop chalcone Xanthohumol analogues 164
Conformational effects on the activity of drugs. Synthesis and adrenergic properties of 2-methyl-substituted 3-(3,4- dihydroxyphenyl)-3-piperidinols 163
Aryl-substituted methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: effects of some structural modifications on their biological properties 163
Transthyretin amyloidosis: a computational approach toward the design of new inhibitors 160
Powerful twin carboxylic inhibitors for MMP homodimerization 159
2-(phenylsulphonamido)-pyrazole derivatives as carbonic anhydrase inhibitors 159
New Hybrid Compounds Incorporating Natural Products as Multifunctional Agents against Alzheimer's Disease 158
Synthesis and adrenergic beta-blocking activity of ortho-, meta- and para-oxypropanolamino-substituted [(benzylideneamino)oxy]propanolamines. 158
(E)-(ARYLMETHYLENEAMINOXY)ACETAMIDES AS ANALOGS OF NEUROLEPTIC BENZAMIDES - SYNTHESIS AND D-2-DOPAMINERGIC BINDING-AFFINITY 157
Oxy-imino saccharidic derivatives as a new structural class of aldose reductase inhibitors endowed with anti-oxidant activity 157
Omega-3 PUFAs as a Dietary Supplement in Senile Systemic Amyloidosis 156
N-i-Propoxy-N-biphenylsulfonylaminobutylhydroxamic acids as potent and selective inhibitors of MMP-2 and MT1-MMP 155
A new crystal form of human transthyretin obtained with a curcumin derived ligand 154
Design, synthesis, biological evaluation and NMR studies of a new series of arylsulfones as selective and potent MMP-12 inhibitors 153
Comparison of helical scan and standard rotation methods in single-crystal X-ray data collection strategies 153
SYNTHESIS, PLATELET ANTI-AGGREGATING ACTIVITY AND ANTIINFLAMMATORY ACTIVITY OF A SERIES OF BETA-AMINOXYPROPIONIC ACIDS 152
Synthesis and antiviral properties of 9-[(2-methyleneaminoxyethoxy)methyl]guanine derivatives as novel acyclovir analogues 152
Structural Insights on Carbonic Anhydrase Inhibitory Action, Isoform Selectivity, and Potency of Sulfonamides and Coumarins Incorporating Arylsulfonylureido Groups 152
Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR) 152
Synthesis and prostaglandin synthase inhibitory activity of new aromatic O-alkyloxime ethers substituted with methylsulfonamido or methylsulfonyl groups on their aliphatic portion 151
Nature-Inspired O-Benzyl Oxime-Based Derivatives as New Dual-Acting Agents Targeting Aldose Reductase and Oxidative Stress 150
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma 150
X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors 150
Pomegranate: A Source of Multifunctional Bioactive Compounds Potentially Beneficial in Alzheimer’s Disease 149
Human transthyretin (TTR) complexed with (E)-3-(2-methoxybenzylideneaminooxy)propanoic acid (inhibitor 13) 149
Sintesi ed attività adrenergica di analoghi ciclici dell’1-(2,5-dimetossifenil)-2-amminoetanolo 147
1-(PHENYLSULPHONAMIDO)-PYRAZOLE DERIVATIVES AS CARBONIC ANHYDRASE INHIBITORS. 147
NMR STUDIES OF A NEW POTENT MMP-12 INHIBITOR: INSIGHT INTO KEY BINDING INTERACTIONS 145
SYNTHESIS, ANTIINFLAMMATORY ACTIVITY AND PLATELET ANTIAGGREGATING ACTIVITY OF A NEW SERIES OF BETA-AMINOXYPROPIONIC ACIDS 145
Synthesis and aldose reductase inhibitory activity of new N-(benzyloxy) glycine derivatives 145
Synthesis and COX2 inhibitory properties of N-Phenyl-and N-benzyl-substituted amides of 2-(4-methylsulfonylphenyl)cyclopent-1-ene-1-carboxylic acid and of their pyrazole, thiophene, and isoxazole analogs 145
Carbonic anhydrase and matrix metalloproteinase inhibitors. Inhibition of human tumor-associated isozymes IX and cytosolic isozyme I and II with sulfonylated hydroxamates 145
Totale 18.058
Categoria #
all - tutte 79.152
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 79.152


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.976 0 219 47 98 351 262 72 98 63 47 129 590
2022/20232.572 341 355 197 241 258 342 21 172 431 6 153 55
2023/20241.739 222 176 183 89 276 359 91 38 27 39 73 166
2024/20255.608 22 210 121 299 569 472 547 337 525 712 580 1.214
2025/20266.504 518 856 734 540 566 557 1.007 284 356 584 247 255
2026/2027390 294 96 0 0 0 0 0 0 0 0 0 0
Totale 27.712