CINECA IRIS Institutional Research Information System

COSTA, BARBARA
 Distribuzione geografica
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Continente #
NA - Nord America 9.927
EU - Europa 4.889
AS - Asia 1.346
AF - Africa 139
OC - Oceania 50
SA - Sud America 9
Continente sconosciuto - Info sul continente non disponibili 5
Totale 16.365
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Nazione #
US - Stati Uniti d'America 9.620
IT - Italia 2.074
CN - Cina 760
SE - Svezia 724
DE - Germania 679
BG - Bulgaria 436
CA - Canada 302
TR - Turchia 234
GB - Regno Unito 230
UA - Ucraina 161
VN - Vietnam 160
FI - Finlandia 158
AT - Austria 120
RU - Federazione Russa 75
SG - Singapore 61
CI - Costa d'Avorio 58
IN - India 50
FR - Francia 49
BE - Belgio 47
AU - Australia 46
CH - Svizzera 42
SN - Senegal 40
HK - Hong Kong 37
NG - Nigeria 35
GR - Grecia 22
NL - Olanda 21
PL - Polonia 15
KR - Corea 11
JP - Giappone 10
IR - Iran 6
CZ - Repubblica Ceca 5
ES - Italia 5
HU - Ungheria 5
IE - Irlanda 5
BR - Brasile 4
DK - Danimarca 4
EU - Europa 4
IL - Israele 4
MA - Marocco 4
NZ - Nuova Zelanda 4
CL - Cile 3
RO - Romania 3
TW - Taiwan 3
EE - Estonia 2
HR - Croazia 2
ID - Indonesia 2
MX - Messico 2
A1 - Anonimo 1
AE - Emirati Arabi Uniti 1
AR - Argentina 1
AZ - Azerbaigian 1
GE - Georgia 1
GH - Ghana 1
GL - Groenlandia 1
JM - Giamaica 1
JO - Giordania 1
KZ - Kazakistan 1
MC - Monaco 1
MD - Moldavia 1
MM - Myanmar 1
MY - Malesia 1
PA - Panama 1
PE - Perù 1
PH - Filippine 1
PT - Portogallo 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
ZA - Sudafrica 1
Totale 16.365
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Città #
Woodbridge 1.598
Ann Arbor 1.276
Houston 1.056
Serra 924
Fairfield 890
Chandler 865
Ashburn 504
Sofia 436
Milan 328
Wilmington 326
Seattle 322
New York 289
Ottawa 285
Beijing 279
Cambridge 253
Izmir 229
Princeton 202
Jacksonville 195
Lawrence 172
Nanjing 154
Medford 148
Des Moines 134
Vienna 112
Frankfurt am Main 99
Dong Ket 98
Dearborn 74
Abidjan 58
London 56
Los Angeles 55
Nanchang 51
Florence 46
Brussels 45
San Diego 43
Dakar 40
Bremen 39
Bern 37
Sydney 37
Lagos 35
Redwood City 35
Nürnberg 33
Rho 33
Hong Kong 32
Rome 32
Boulder 31
Pisa 31
Kunming 30
Lancaster 30
Pistoia 30
Jüchen 29
Changsha 28
Falls Church 28
Shenyang 28
Jiaxing 26
Norwalk 25
Auburn Hills 23
Hefei 23
Hebei 22
Boardman 21
Ogden 20
Santa Margherita Ligure 20
Guangzhou 19
Pune 19
Hangzhou 17
Tianjin 17
Livorno 15
Lucca 13
Alessandria 12
Düsseldorf 12
Jinan 11
Paris 10
Warsaw 10
Dortmund 9
Helsinki 9
Phoenix 9
Toronto 9
Marseille 8
Washington 8
Council Bluffs 7
Dallas 7
Indiana 7
Orange 7
Capannori 6
Caserta 6
Detroit 6
Massa 6
Melbourne 6
San Francisco 6
Tokyo 6
Vercelli 6
Amsterdam 5
Augusta 5
Bari 5
Dublin 5
Grosseto 5
Naples 5
North York 5
Shanghai 5
Viareggio 5
Bangalore 4
Budapest 4
Totale 12.736
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Nome #
TSPO ligand residence time influences human glioblastoma multiforme cell death/life balance 249
null 236
Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma 212
AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cells 203
Ala147Thr amino acid substitution within the translocator protein (TSPO) influences pregnenolone production in lymphomonocytes 192
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells 179
N, N-Dialkyl-2-phenylindol-3-ylglyoxylamides.A new class of potent and selective ligands at the Peripheral benzodiazepine receptor 175
An antibody-free strategy for screening putative HDM2 inhibitors using crude bacterial lysates expressing GST-HDM2 recombinant protein 174
The Citrus Flavanone Naringenin Protects Myocardial Cells against Age-Associated Damage 171
IL POLIMORFISMO ALA147THR ALL’INTERNO DEL TRASLOCATORE PROTEICO (TSPO) INFLUENZA LA PRODUZIONE DI PREGNENOLONE NEI LINFO-MONOCITI DI SOGGETTI SANI 170
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization 161
TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy 161
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 160
Identification of Anxiolytic/Nonsedative Agents among Indol-3-ylglyoxylamides Acting as Functionally Selective Agonists at the γ-Aminobutyric Acid-A (GABAA) α2 Benzodiazepine Receptor 159
TSPO PIGA ligands promote neurosteroidogenesis and human astrocyte well-being 157
TSPO over-expression increases motility, transmigration and proliferation properties of C6 rat glioma cells 150
Drug-target Residence Time: a key parameter in glial responses to TSPO ligands 146
A (2A) ADENOSINE RECEPTOR LIGANDS AND PROINFLAMMATORY CYTOKINES INDUCE PC12 CELL DEATH THROUGH APOPTOSIS 145
Evaluation of 2,3,4,8,13a hexahydro-1H-benzo[5,6]cyclohepta-6,7-dihydroxy[1,2,3-ef][3]benzazepine derivatives as dopamine receptor ligands 145
5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: affinity, efficacy, and selectivity for A1 receptor from different species 143
Attivazione di segnali per l'induzione dell'apoptosi e/o per la sopravvivenza cellulare da parte di ligandi selettivi per il recettore periferico delle benzodiazepine 142
Residence Time (RT), a new parameter to predict neurosteroidogenic efficacy of Translocator Protein (TSPO) ligands: N,N-dialkyl-2-arylindol-3-ylglyoxylamides, a case study 142
Translocator protein as a promising target for novel anxiolytics 141
Oxytocin receptor and G-protein polymorphisms in patients with depression and separation anxiety 141
Role of Translocator Protein (18 kDa) in Adult Separation Anxiety and Attachment Style in Patients with Depression. 140
TSPO-ligands prevent oxidative damage and inflammatory response in C6 glioma cells by neurosteroid synthesis 139
Analysis of the Antitumor Activity of Clotrimazole on A375 Human Melanoma Cells 138
Oxytocin receptor gene variation, behavioural inhibition, and adult separation anxiety: role in complicated grief 137
Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors 135
Epigenetic Modifications of the α-Synuclein Gene and Relative Protein Content Are Affected by Ageing and Physical Exercise in Blood from Healthy Subjects 135
Long Residence Time at the Neurosteroidogenic 18 kDa Translocator Protein Characterizes the Anxiolytic Ligand XBD173 134
The Spontaneous Ala147Thr Amino Acid Substitution within the Translocator Protein Influences Pregnenolone Production in Lymphomonocytes of Healthy Individuals 132
Targeting the 18-kDa translocator protein: Recent perspectives for neuroprotection 132
Human glioblastoma multiforme: p53 reactivation by a novel MDM2 inhibitor 131
C-Nucleoside analogues of furanfurin as ligands to A1 adenosine receptors 129
Ala147Thrsubstitution in translocator protein is associated with adult separation anxiety in patients with depression 128
Translocator Protein (TSPO) and Neurosteroids: Implications in Psychiatric Disorders. 126
Peripheral benzodiazepine receptor: characterization in human T-lymphoma Jurkat cells 123
The Anxiolytic Etifoxine Binds to TSPO Ro5-4864 Binding Site with Long Residence Time Showing a High Neurosteroidogenic Activity 123
Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: The use of natural compounds as modulatory agents 123
Benzodiazepine receptor ligands. 8: Synthesis and pharmacological evaluation of new pyrazolo[5,1-c] [1,2,4]benzotriazine 5-oxide 3- and 8-disubstituted: High affinity ligands endowed with inverse-agonist pharmacological efficacy 122
Oxytocin receptor polymorphisms and adult attachment style in patients with depression 122
Chemical modification of the dihydropyridines binding sites by lysine reagent, pyridoxal 5’-phosphate 121
2,9-Disubstituted-N6-(arylcarbamoyl)-8-azaadenines as new selective A3 adenosine receptor antagonists: Synthesis, biochemical and molecular modelling studies 120
2-Arylpyrazolo[1,5-a]pyrimidin-3-yl acetamides. New potent and selective peripheral benzodiazepine receptor ligands 120
Studies in search for selective ligands for GABAA/BzR receptor subtypes: synthesis and biological evaluation of 4'-modified N-(benzyl)indol-3-ylglyoxylamides 119
Synthesis and Biological Evaluation of 4-Phenylquinazoline-2-carboxamides Designed as a Novel Class of Potent Ligands of the Translocator Protein 119
Benzodiazepine receptor ligands. 7. Synthesis and pharmacological evaluation of new 3-esters of the 8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide. 3-(2-Thienylmethoxycarbonyl) derivative: an anxioselective agent in rodents 118
An update into the medicinal chemistry of translocator protein (TSPO) ligands 117
A2A adenosine receptor: solubilization from bovine striatal membranes by digitonin detergent. 115
Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene)sulfonamido-based hydroxamates as matrix metalloproteinase inhibitors 114
Reductions in platelet 18-kDa translocator protein density are associated with adult separation anxiety in patients with bipolar disorder 113
Serotonin: a signaling molecule during embryonal development of the amphibian Xenopus laevis 113
Tertiary amides with a five-membered heteroaromatic ring as new probes for the translocator protein 113
ERYTHRO AND THREO 2-HYDROXYNONYL SUBSTITUTED 2-PHENYLADENINES AND 2-PHENYL-8-AZAADENINES: LIGANDS FOR A1 ADENOSINE RECEPTORS AND ADENOSINE DEAMINASE 112
Characterization of a cloned xenopus laevis serotonin 5-HT1A receptor expressed in the NIH-3T3 cell line. 112
A2a Adenosine Receptors: guanine nucleotide derivative regulation in porcine striatal membranes and digitonin soluble fraction 111
2,3-butanedione inactivates the [H-3]nitrendipine binding sites, whereas diethylpyrocarbonate does not 109
An irreversible ligand of the 18 kDa Translocator Protein induces rapidly ΔΨm collapse and activates apoptosis in human glioblastoma multiforme cells. 108
Translocator protein (TSPO) and identification of new molecular diagnosis tools 107
DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterization 107
Benzodiazepine receptor ligands-Part II. Synthesis and biological evaluation of pyrazolo[5,1-c][1,2,4]benzotriazine 4-oxide 107
Antitumoral effect by induction of collapse of mitochondrial membrane potential in Glioblastoma Multiforme cells 106
Peripheral type benzodiazepine receptor in human parathyroid glands: up-regulation in adenoma 106
Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: Stimulation of in vitro neurosteroid production affecting GABA(A) receptor activity 106
PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a new mitochondrial benzodiazepine-receptor ligand, induces apoptosis in C6 glioma cells 105
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: synthesis, biological evaluation and 3D-QSAR investigation 103
Powerful twin carboxylic inhibitors for MMP homodimerization 103
18-kDa translocator protein association complexes in the brain: From structure to function 103
Synthesis and benzodiazepine receptor binding activity of 2, 9-disubstituted quinolino[2', 3'-5, 4](3-pyrazolino)[3, 2-b]purin-4-ones 102
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma 101
Characterization of a voltage-dependent L-type calcium channel from rabbit and turtle brain 100
Bioisosterism, enantioselectivity and molecular modeling of new effective N6- and/or N(9)-substituted 2-phenyl adenines and 8-aza analogs: different binding modes to A1 adenosine receptors 100
Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO) 99
Synthesis of Novel 4-Aryl-1,2,3,4-tetrahydroisoquinolines as Probes for Dopamine Receptor Ligands. 99
A2A adenosine receptors and cytokines: modulation of apoptosis in PC12 cells 98
Synthesis and BZR affinity of pyrazolo[1,5-a]pyrimidine derivatives. Part 1: study of the structural features for BZR recognition 98
Mutation analysis of oxytocin gene in individuals with adult separation anxiety 98
The peripheral-type benzodiazepine receptor ligand PK 11195 induces mitochondrial permeability transition and apoptosis in human healthy lymphocytes 97
N,N-Dialkyl-2-phenylindol-3- ylglyoxylamides. A New Class of Potent and Selective Ligands at the Peripheral Benzodiazepine Receptor 97
C825T POLYMORPHISM OF G-PROTEIN BETA3 GENE INPATIENTS WITH DSM-IV PANIC DISORDER 96
pyrazolo [1,5-a]pyrimidines: new peripheral benzodiazepine receptor ligands 96
Oxytocin receptor polymorphisms and adult attachment style in patients with depression 96
C825T Polymorphism of the G- protein beta 3 gene in patients with panic disorder 95
Translocator protein and steroidogenesis 95
Translocator protein (tspo) ligand residence time: a new parameter to predict neurosteroidogenic efficacy for n,n-dialkyl-2-arylindol-3-ylglyoxylamides (PIGAs) 94
Structure-Activity Relationship Refinement and Further Assessment of 4-Phenylquinazoline-2-carboxamide Translocator Protein Ligands as Antiproliferative Agents in Human Glioblastoma Tumors. 94
PK 11195 differentially affects cell survival in human wild-type and 18 kDa translocator protein-silenced ADF astrocytoma cells 93
Relazione tra densità del recttore periferico delle benzodiazepine (PBR) e tumorogenicità delle cellule di glioma: produzione di linee cellulari ingegnerizzate a sovraesprimere il PBR 92
A 2-phenylindol-3-ylglyoxylammide derivative, a new-synthesized peripheral benzodiazepine receptor ligand, induces apoptosis in rat C6 glioma cells 91
Effects of selective MMP-2 inhibitors on viability and invasiveness in the U87MG human glioblastoma cell line 91
Functional expression of the Xenopus laevis 5-hydroxytryptamine1A receptor gene in NIH3T3 cells 90
Peripheral benzodiazepine receptor ligands: mitochondrial transmembrane potential depolarization and apoptosis induction in rat C6 glioma cells 90
Synthesis, biological evaluation, and molecular modeling of ribose-modified adenosine analogues as adenosine receptor agonists 88
Microglial pro-inflammatory and anti-inflammatory phenotypes are modulated by translocator protein activation 88
SYNTHESIS AND BIOLOGICAL EVALUATION OF 5'-CARBAMOYL- DERIVATIVES OF A1 ADENOSINE RECEPTOR AGONISTS MODIFIED IN THE RIBOSE MOIETY 87
Benzodiazepine receptor ligands. 4. Synthesis and pharmacological evaluation of 3-heteroaryl-8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxides 87
Human leukemic cell apoptosis induction by peripheral benzodiazepine receptor ligands 86
Novel N-(Arylalkyl)indol-3-ylglyoxylamides targeted as ligands of the benzodiazepine receptor : synthesis, biological evaluation, and molecular modeling analysis of the Structure-Activity Relationships. 86
Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme 85
Totale 12.319
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Categoria #
all - tutte 37.712
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.712
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191.023 0 0 0 0 0 0 0 0 0 426 338 259
2019/20203.104 364 219 739 132 228 297 308 186 235 153 194 49
2020/20211.352 167 67 62 37 156 60 61 140 202 123 85 192
2021/20222.006 44 205 85 101 341 259 83 92 52 37 114 593
2022/20232.673 323 301 162 286 310 356 22 230 469 11 167 36
2023/20241.492 195 181 199 101 244 336 58 97 34 47 0 0
Totale 16.662