CINECA IRIS Institutional Research Information System

COSTA, BARBARA
 Distribuzione geografica
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Continente #
NA - Nord America 15.266
AS - Asia 6.715
EU - Europa 6.192
SA - Sud America 853
Continente sconosciuto - Info sul continente non disponibili 356
AF - Africa 294
OC - Oceania 56
Totale 29.732
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Nazione #
US - Stati Uniti d'America 14.753
IT - Italia 2.387
SG - Singapore 2.001
CN - Cina 1.843
HK - Hong Kong 973
DE - Germania 813
SE - Svezia 750
BR - Brasile 715
VN - Vietnam 715
BG - Bulgaria 436
CA - Canada 382
GB - Regno Unito 358
TR - Turchia 346
FR - Francia 300
FI - Finlandia 262
RU - Federazione Russa 229
IN - India 186
UA - Ucraina 183
JP - Giappone 144
AT - Austria 137
KR - Corea 137
CH - Svizzera 70
CI - Costa d'Avorio 61
BD - Bangladesh 60
IQ - Iraq 56
MX - Messico 54
BE - Belgio 53
AU - Australia 50
NL - Olanda 48
ZA - Sudafrica 44
SN - Senegal 43
NG - Nigeria 39
PL - Polonia 39
PK - Pakistan 37
AR - Argentina 35
ES - Italia 32
SA - Arabia Saudita 31
MA - Marocco 25
ID - Indonesia 24
CO - Colombia 23
GR - Grecia 23
EC - Ecuador 21
VE - Venezuela 21
JO - Giordania 19
UZ - Uzbekistan 18
KE - Kenya 17
EG - Egitto 14
JM - Giamaica 14
TT - Trinidad e Tobago 13
PH - Filippine 12
AE - Emirati Arabi Uniti 11
AZ - Azerbaigian 11
IE - Irlanda 11
CL - Cile 10
IL - Israele 10
MY - Malesia 10
CR - Costa Rica 9
CZ - Repubblica Ceca 9
DZ - Algeria 9
ET - Etiopia 9
OM - Oman 9
GT - Guatemala 8
HU - Ungheria 8
IR - Iran 8
LT - Lituania 8
PY - Paraguay 8
BJ - Benin 7
NP - Nepal 7
PE - Perù 7
BB - Barbados 6
LB - Libano 6
NZ - Nuova Zelanda 6
TN - Tunisia 6
TW - Taiwan 6
UY - Uruguay 6
DK - Danimarca 5
KZ - Kazakistan 5
PA - Panama 5
PT - Portogallo 5
RO - Romania 5
DO - Repubblica Dominicana 4
EU - Europa 4
GE - Georgia 4
HN - Honduras 4
KG - Kirghizistan 4
PR - Porto Rico 4
AL - Albania 3
AM - Armenia 3
BH - Bahrain 3
BO - Bolivia 3
EE - Estonia 3
GH - Ghana 3
GY - Guiana 3
NI - Nicaragua 3
PS - Palestinian Territory 3
SK - Slovacchia (Repubblica Slovacca) 3
BW - Botswana 2
BY - Bielorussia 2
CY - Cipro 2
HR - Croazia 2
Totale 29.338
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Città #
Woodbridge 1.598
Ashburn 1.392
Ann Arbor 1.276
Singapore 1.121
Houston 1.065
Hong Kong 954
Serra 927
Fairfield 890
Chandler 867
San Jose 746
Santa Clara 681
Dallas 604
Sofia 436
Shanghai 367
Beijing 366
Milan 350
New York 342
Seattle 327
Wilmington 327
Ottawa 288
Cambridge 254
Los Angeles 239
Izmir 230
Boardman 222
Princeton 202
Jacksonville 199
Council Bluffs 195
Ho Chi Minh City 194
Lawrence 172
Hefei 163
Lauterbourg 159
Nanjing 156
Medford 148
Des Moines 135
Frankfurt am Main 131
Tokyo 130
Hanoi 127
Seoul 127
Vienna 122
Pisa 99
Dong Ket 98
Chicago 96
London 90
Istanbul 84
Helsinki 81
Dearborn 74
Florence 71
São Paulo 71
Munich 65
Buffalo 64
Redondo Beach 62
Abidjan 61
Columbus 58
Rome 52
Nanchang 51
Brussels 50
The Dalles 48
Dakar 43
San Diego 43
Bremen 39
Ogden 39
Sydney 39
Bern 37
Lagos 37
Orem 37
Haiphong 36
Redwood City 35
Nürnberg 33
Rho 33
Kunming 32
Pistoia 32
Boulder 31
Changsha 31
Lancaster 31
Jüchen 29
Zurich 29
Falls Church 28
Guangzhou 28
Lucca 28
Shenyang 28
Da Nang 27
Jiaxing 26
Livorno 26
Turku 26
Norwalk 25
Paris 25
Phoenix 25
Atlanta 24
Warsaw 24
Auburn Hills 23
Belo Horizonte 23
Brasília 23
Hebei 22
Baghdad 21
Pune 21
Asnières-sur-Seine 20
Düsseldorf 20
Hangzhou 20
Johannesburg 20
Montreal 20
Totale 20.743
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Nome #
TSPO ligand residence time influences human glioblastoma multiforme cell death/life balance 335
AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cells 335
Ala147Thr amino acid substitution within the translocator protein (TSPO) influences pregnenolone production in lymphomonocytes 323
18 kDa TSPO targeting drives polarized human microglia towards a protective and restorative neurosteroidome profile 319
IL POLIMORFISMO ALA147THR ALL’INTERNO DEL TRASLOCATORE PROTEICO (TSPO) INFLUENZA LA PRODUZIONE DI PREGNENOLONE NEI LINFO-MONOCITI DI SOGGETTI SANI 303
N, N-Dialkyl-2-phenylindol-3-ylglyoxylamides.A new class of potent and selective ligands at the Peripheral benzodiazepine receptor 294
The Citrus Flavanone Naringenin Protects Myocardial Cells against Age-Associated Damage 290
Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma 277
TSPO PIGA ligands promote neurosteroidogenesis and human astrocyte well-being 272
A (2A) ADENOSINE RECEPTOR LIGANDS AND PROINFLAMMATORY CYTOKINES INDUCE PC12 CELL DEATH THROUGH APOPTOSIS 271
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells 258
Translocator Protein 18-kDa: a promising target to treat neuroinflammation-related degenerative diseases 246
An antibody-free strategy for screening putative HDM2 inhibitors using crude bacterial lysates expressing GST-HDM2 recombinant protein 239
null 236
TSPO-ligands prevent oxidative damage and inflammatory response in C6 glioma cells by neurosteroid synthesis 233
TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy 233
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 230
Analysis of the Antitumor Activity of Clotrimazole on A375 Human Melanoma Cells 225
Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors 223
Oxytocin receptor gene variation, behavioural inhibition, and adult separation anxiety: role in complicated grief 221
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization 220
An update into the medicinal chemistry of translocator protein (TSPO) ligands 214
TSPO over-expression increases motility, transmigration and proliferation properties of C6 rat glioma cells 214
Identification of Anxiolytic/Nonsedative Agents among Indol-3-ylglyoxylamides Acting as Functionally Selective Agonists at the γ-Aminobutyric Acid-A (GABAA) α2 Benzodiazepine Receptor 211
Oxytocin receptor and G-protein polymorphisms in patients with depression and separation anxiety 210
Translocator protein as a promising target for novel anxiolytics 204
Long Residence Time at the Neurosteroidogenic 18 kDa Translocator Protein Characterizes the Anxiolytic Ligand XBD173 204
Attivazione di segnali per l'induzione dell'apoptosi e/o per la sopravvivenza cellulare da parte di ligandi selettivi per il recettore periferico delle benzodiazepine 203
Epigenetic Modifications of the α-Synuclein Gene and Relative Protein Content Are Affected by Ageing and Physical Exercise in Blood from Healthy Subjects 202
5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: affinity, efficacy, and selectivity for A1 receptor from different species 201
Studies in search for selective ligands for GABAA/BzR receptor subtypes: synthesis and biological evaluation of 4'-modified N-(benzyl)indol-3-ylglyoxylamides 200
Drug-target Residence Time: a key parameter in glial responses to TSPO ligands 199
Residence Time (RT), a new parameter to predict neurosteroidogenic efficacy of Translocator Protein (TSPO) ligands: N,N-dialkyl-2-arylindol-3-ylglyoxylamides, a case study 198
Benzodiazepine receptor ligands. 8: Synthesis and pharmacological evaluation of new pyrazolo[5,1-c] [1,2,4]benzotriazine 5-oxide 3- and 8-disubstituted: High affinity ligands endowed with inverse-agonist pharmacological efficacy 195
2,9-Disubstituted-N6-(arylcarbamoyl)-8-azaadenines as new selective A3 adenosine receptor antagonists: Synthesis, biochemical and molecular modelling studies 195
Translocator protein (tspo) ligand residence time: a new parameter to predict neurosteroidogenic efficacy for n,n-dialkyl-2-arylindol-3-ylglyoxylamides (PIGAs) 195
Ala147Thrsubstitution in translocator protein is associated with adult separation anxiety in patients with depression 194
Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: The use of natural compounds as modulatory agents 194
The Spontaneous Ala147Thr Amino Acid Substitution within the Translocator Protein Influences Pregnenolone Production in Lymphomonocytes of Healthy Individuals 192
The Anxiolytic Etifoxine Binds to TSPO Ro5-4864 Binding Site with Long Residence Time Showing a High Neurosteroidogenic Activity 192
The human microglial surveillant phenotype is preserved by de novo neurosteroidogenesis through the control of cholesterol homeostasis: Crucial role of 18 kDa Translocator Protein 191
Evaluation of 2,3,4,8,13a hexahydro-1H-benzo[5,6]cyclohepta-6,7-dihydroxy[1,2,3-ef][3]benzazepine derivatives as dopamine receptor ligands 190
Human glioblastoma multiforme: p53 reactivation by a novel MDM2 inhibitor 190
Sex Differences in Blood Accumulation of Neurodegenerative-Related Proteins and Antioxidant Responses to Regular Physical Exercise 187
Translocator Protein (TSPO) and Neurosteroids: Implications in Psychiatric Disorders. 186
An irreversible ligand of the 18 kDa Translocator Protein induces rapidly ΔΨm collapse and activates apoptosis in human glioblastoma multiforme cells. 186
Discovery of the First-in-Class Dual TSPO/Carbonic Anhydrase Modulators with Promising Neurotrophic Activity 185
Reductions in platelet 18-kDa translocator protein density are associated with adult separation anxiety in patients with bipolar disorder 183
2,3-butanedione inactivates the [H-3]nitrendipine binding sites, whereas diethylpyrocarbonate does not 183
Targeting the 18-kDa translocator protein: Recent perspectives for neuroprotection 183
Role of Translocator Protein (18 kDa) in Adult Separation Anxiety and Attachment Style in Patients with Depression. 183
Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene)sulfonamido-based hydroxamates as matrix metalloproteinase inhibitors 179
Translocator protein and steroidogenesis 178
Antitumoral effect by induction of collapse of mitochondrial membrane potential in Glioblastoma Multiforme cells 177
Peripheral benzodiazepine receptor: characterization in human T-lymphoma Jurkat cells 177
De novo neurosteroidogenesis in human microglia: Involvement of the 18 kda translocator protein 176
Carbonic anhydrase activation profile of indole-based derivatives 175
null 173
Synthesis and Biological Evaluation of 4-Phenylquinazoline-2-carboxamides Designed as a Novel Class of Potent Ligands of the Translocator Protein 172
DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterization 171
Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: Stimulation of in vitro neurosteroid production affecting GABA(A) receptor activity 171
The relationship of separation anxiety with the age of onset of panic disorder 170
Microglial pro-inflammatory and anti-inflammatory phenotypes are modulated by translocator protein activation 170
2-Arylpyrazolo[1,5-a]pyrimidin-3-yl acetamides. New potent and selective peripheral benzodiazepine receptor ligands 170
Serotonin: a signaling molecule during embryonal development of the amphibian Xenopus laevis 169
A2A adenosine receptor: solubilization from bovine striatal membranes by digitonin detergent. 168
Oxytocin receptor polymorphisms and adult attachment style in patients with depression 168
Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO) 168
Compounds with a benzo [a]carbazole structure for use in the prevention and/or treatment of infectious diseases 167
C-Nucleoside analogues of furanfurin as ligands to A1 adenosine receptors 167
Bioisosterism, enantioselectivity and molecular modeling of new effective N6- and/or N(9)-substituted 2-phenyl adenines and 8-aza analogs: different binding modes to A1 adenosine receptors 167
PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a new mitochondrial benzodiazepine-receptor ligand, induces apoptosis in C6 glioma cells 166
Chemical modification of the dihydropyridines binding sites by lysine reagent, pyridoxal 5’-phosphate 166
Relazione tra densità del recttore periferico delle benzodiazepine (PBR) e tumorogenicità delle cellule di glioma: produzione di linee cellulari ingegnerizzate a sovraesprimere il PBR 166
Unbinding of Translocator Protein 18 kDa (TSPO) Ligands: From in Vitro Residence Time to in Vivo Efficacy via in Silico Simulations 165
Translocator protein (TSPO) and identification of new molecular diagnosis tools 164
Characterization of a voltage-dependent L-type calcium channel from rabbit and turtle brain 164
Benzodiazepine receptor ligands. 7. Synthesis and pharmacological evaluation of new 3-esters of the 8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide. 3-(2-Thienylmethoxycarbonyl) derivative: an anxioselective agent in rodents 164
Tertiary amides with a five-membered heteroaromatic ring as new probes for the translocator protein 162
Benzodiazepine receptor ligands-Part II. Synthesis and biological evaluation of pyrazolo[5,1-c][1,2,4]benzotriazine 4-oxide 162
PK 11195 differentially affects cell survival in human wild-type and 18 kDa translocator protein-silenced ADF astrocytoma cells 162
Regular exercise delays microvascular endothelial dysfunction by regulating antioxidant capacity and cellular metabolism 162
The peripheral-type benzodiazepine receptor ligand PK 11195 induces mitochondrial permeability transition and apoptosis in human healthy lymphocytes 160
N,N-Dialkyl-2-phenylindol-3- ylglyoxylamides. A New Class of Potent and Selective Ligands at the Peripheral Benzodiazepine Receptor 160
18-kDa translocator protein association complexes in the brain: From structure to function 160
Refinement of the translocator protein pharmacophore/receptor model via structure-activity relationships of novel N,N-dialkylindolylglyoxylamides 159
Synthesis, biological evaluation, and molecular modeling of ribose-modified adenosine analogues as adenosine receptor agonists 159
Powerful twin carboxylic inhibitors for MMP homodimerization 159
Oxytocin receptor polymorphisms and adult attachment style in patients with depression 158
A2A adenosine receptors and cytokines: modulation of apoptosis in PC12 cells 157
A2a Adenosine Receptors: guanine nucleotide derivative regulation in porcine striatal membranes and digitonin soluble fraction 157
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: synthesis, biological evaluation and 3D-QSAR investigation 156
Targeting the Translocator Protein (18 kDa) in Cardiac Diseases: State of the Art and Future Opportunities 155
Characterization of a cloned xenopus laevis serotonin 5-HT1A receptor expressed in the NIH-3T3 cell line. 154
ERYTHRO AND THREO 2-HYDROXYNONYL SUBSTITUTED 2-PHENYLADENINES AND 2-PHENYL-8-AZAADENINES: LIGANDS FOR A1 ADENOSINE RECEPTORS AND ADENOSINE DEAMINASE 153
A 2-phenylindol-3-ylglyoxylammide derivative, a new-synthesized peripheral benzodiazepine receptor ligand, induces apoptosis in rat C6 glioma cells 153
Mutation analysis of oxytocin gene in individuals with adult separation anxiety 153
C825T Polymorphism of the G- protein beta 3 gene in patients with panic disorder 152
Structure-Activity Relationship Refinement and Further Assessment of 4-Phenylquinazoline-2-carboxamide Translocator Protein Ligands as Antiproliferative Agents in Human Glioblastoma Tumors. 151
Inhibition of metalloproteinases derived from tumours: new insights in the treatment of human glioblastoma 150
Totale 19.489
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Categoria #
all - tutte 80.657
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 80.657
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.962 0 205 85 101 341 259 83 92 52 37 114 593
2022/20232.673 323 301 162 286 310 356 22 230 469 11 167 36
2023/20241.881 195 181 199 105 248 336 60 97 34 76 104 246
2024/20255.527 52 219 54 322 538 573 349 277 584 768 584 1.207
2025/20266.452 503 757 713 376 612 606 1.278 307 365 534 250 151
2026/2027702 228 474 0 0 0 0 0 0 0 0 0 0
Totale 29.732