CINECA IRIS Institutional Research Information System

COSTA, BARBARA
 Distribuzione geografica
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Continente #
NA - Nord America 17.152
AS - Asia 6.732
EU - Europa 6.264
SA - Sud America 892
Continente sconosciuto - Info sul continente non disponibili 358
AF - Africa 296
OC - Oceania 56
Totale 31.750
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Nazione #
US - Stati Uniti d'America 16.558
IT - Italia 2.439
SG - Singapore 2.002
CN - Cina 1.848
HK - Hong Kong 976
DE - Germania 813
SE - Svezia 750
BR - Brasile 749
VN - Vietnam 716
BG - Bulgaria 436
CA - Canada 431
GB - Regno Unito 368
TR - Turchia 347
FR - Francia 300
FI - Finlandia 262
RU - Federazione Russa 229
IN - India 186
UA - Ucraina 183
JP - Giappone 144
AT - Austria 137
KR - Corea 137
CH - Svizzera 70
BD - Bangladesh 61
CI - Costa d'Avorio 61
IQ - Iraq 56
MX - Messico 54
BE - Belgio 53
AU - Australia 50
NL - Olanda 49
ZA - Sudafrica 44
SN - Senegal 43
NG - Nigeria 39
PL - Polonia 39
PK - Pakistan 37
AR - Argentina 36
ES - Italia 33
SA - Arabia Saudita 31
ID - Indonesia 26
MA - Marocco 25
CO - Colombia 24
GR - Grecia 23
EC - Ecuador 22
VE - Venezuela 21
JO - Giordania 19
JM - Giamaica 18
UZ - Uzbekistan 18
KE - Kenya 17
EG - Egitto 16
CR - Costa Rica 15
PH - Filippine 14
TT - Trinidad e Tobago 13
AE - Emirati Arabi Uniti 11
AZ - Azerbaigian 11
CL - Cile 11
IE - Irlanda 11
NI - Nicaragua 11
CZ - Repubblica Ceca 10
GT - Guatemala 10
IL - Israele 10
MY - Malesia 10
DZ - Algeria 9
ET - Etiopia 9
OM - Oman 9
HU - Ungheria 8
IR - Iran 8
LT - Lituania 8
NP - Nepal 8
PY - Paraguay 8
BB - Barbados 7
BJ - Benin 7
HN - Honduras 7
PE - Perù 7
PR - Porto Rico 7
LB - Libano 6
NZ - Nuova Zelanda 6
SI - Slovenia 6
TN - Tunisia 6
TW - Taiwan 6
UY - Uruguay 6
DK - Danimarca 5
DO - Repubblica Dominicana 5
EE - Estonia 5
KZ - Kazakistan 5
PA - Panama 5
PT - Portogallo 5
RO - Romania 5
BO - Bolivia 4
EU - Europa 4
GE - Georgia 4
KG - Kirghizistan 4
AL - Albania 3
AM - Armenia 3
BH - Bahrain 3
GH - Ghana 3
GY - Guiana 3
PS - Palestinian Territory 3
SK - Slovacchia (Repubblica Slovacca) 3
SV - El Salvador 3
AW - Aruba 2
BW - Botswana 2
Totale 31.350
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Città #
Ashburn 1.838
Woodbridge 1.599
Ann Arbor 1.277
Singapore 1.122
Houston 1.070
Hong Kong 957
Serra 927
San Jose 904
Fairfield 891
Chandler 868
Santa Clara 693
Dallas 617
Council Bluffs 453
Sofia 436
Beijing 369
Shanghai 367
New York 358
Milan 354
Wilmington 329
Seattle 327
Ottawa 290
Los Angeles 270
Cambridge 256
Izmir 230
Boardman 223
Jacksonville 203
Princeton 202
Ho Chi Minh City 194
Lawrence 172
Hefei 163
Lauterbourg 159
Nanjing 156
Medford 149
Des Moines 135
Frankfurt am Main 131
Tokyo 130
Hanoi 127
Seoul 127
Vienna 122
Chicago 111
Pisa 103
São Paulo 99
Dong Ket 98
London 91
Istanbul 84
Helsinki 81
Buffalo 80
Dearborn 74
Florence 74
Munich 65
Redondo Beach 62
Abidjan 61
Columbus 59
Rome 52
Nanchang 51
Brussels 50
The Dalles 48
Toronto 46
San Diego 45
Dakar 43
Phoenix 40
Bremen 39
Ogden 39
Sydney 39
Orem 38
Bern 37
Lagos 37
Haiphong 36
Redwood City 35
Nürnberg 33
Rho 33
Kunming 32
Lancaster 32
Pistoia 32
Boulder 31
Changsha 31
Livorno 31
Jüchen 29
Zurich 29
Atlanta 28
Brasília 28
Falls Church 28
Guangzhou 28
Lucca 28
Shenyang 28
Da Nang 27
Montreal 27
Jiaxing 26
Turku 26
Norwalk 25
Paris 25
Denver 24
Warsaw 24
Auburn Hills 23
Belo Horizonte 23
Hebei 22
San Francisco 22
Baghdad 21
Manchester 21
Pune 21
Totale 21.850
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Nome #
AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cells 349
TSPO ligand residence time influences human glioblastoma multiforme cell death/life balance 345
Ala147Thr amino acid substitution within the translocator protein (TSPO) influences pregnenolone production in lymphomonocytes 338
18 kDa TSPO targeting drives polarized human microglia towards a protective and restorative neurosteroidome profile 324
IL POLIMORFISMO ALA147THR ALL’INTERNO DEL TRASLOCATORE PROTEICO (TSPO) INFLUENZA LA PRODUZIONE DI PREGNENOLONE NEI LINFO-MONOCITI DI SOGGETTI SANI 319
N, N-Dialkyl-2-phenylindol-3-ylglyoxylamides.A new class of potent and selective ligands at the Peripheral benzodiazepine receptor 306
The Citrus Flavanone Naringenin Protects Myocardial Cells against Age-Associated Damage 297
2,9-Disubstituted-N6-(arylcarbamoyl)-8-azaadenines as new selective A3 adenosine receptor antagonists: Synthesis, biochemical and molecular modelling studies 294
Apoptosis Therapy in Cancer: The First Single-molecule Co-activating p53 and the Translocator Protein in Glioblastoma 284
A (2A) ADENOSINE RECEPTOR LIGANDS AND PROINFLAMMATORY CYTOKINES INDUCE PC12 CELL DEATH THROUGH APOPTOSIS 280
TSPO PIGA ligands promote neurosteroidogenesis and human astrocyte well-being 278
Bax Activation Blocks Self-Renewal and Induces Apoptosis of Human Glioblastoma Stem Cells 265
Translocator Protein 18-kDa: a promising target to treat neuroinflammation-related degenerative diseases 251
An antibody-free strategy for screening putative HDM2 inhibitors using crude bacterial lysates expressing GST-HDM2 recombinant protein 248
TSPO-ligands prevent oxidative damage and inflammatory response in C6 glioma cells by neurosteroid synthesis 240
TSPO ligand residence time: a new parameter to predict compound neurosteroidogenic efficacy 240
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells 239
null 236
Analysis of the Antitumor Activity of Clotrimazole on A375 Human Melanoma Cells 235
Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors 232
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization 232
Oxytocin receptor gene variation, behavioural inhibition, and adult separation anxiety: role in complicated grief 228
TSPO over-expression increases motility, transmigration and proliferation properties of C6 rat glioma cells 224
Oxytocin receptor and G-protein polymorphisms in patients with depression and separation anxiety 218
Identification of Anxiolytic/Nonsedative Agents among Indol-3-ylglyoxylamides Acting as Functionally Selective Agonists at the γ-Aminobutyric Acid-A (GABAA) α2 Benzodiazepine Receptor 217
An update into the medicinal chemistry of translocator protein (TSPO) ligands 217
Translocator protein as a promising target for novel anxiolytics 214
Attivazione di segnali per l'induzione dell'apoptosi e/o per la sopravvivenza cellulare da parte di ligandi selettivi per il recettore periferico delle benzodiazepine 212
Long Residence Time at the Neurosteroidogenic 18 kDa Translocator Protein Characterizes the Anxiolytic Ligand XBD173 212
5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: affinity, efficacy, and selectivity for A1 receptor from different species 210
Benzodiazepine receptor ligands - III. Synthesis and biological evaluation of 2-and/or 3-substituted pyrazolo[5,1-c][l,2,4]benzotriazine 5-oxides 210
Studies in search for selective ligands for GABAA/BzR receptor subtypes: synthesis and biological evaluation of 4'-modified N-(benzyl)indol-3-ylglyoxylamides 209
Drug-target Residence Time: a key parameter in glial responses to TSPO ligands 207
Epigenetic Modifications of the α-Synuclein Gene and Relative Protein Content Are Affected by Ageing and Physical Exercise in Blood from Healthy Subjects 207
Residence Time (RT), a new parameter to predict neurosteroidogenic efficacy of Translocator Protein (TSPO) ligands: N,N-dialkyl-2-arylindol-3-ylglyoxylamides, a case study 206
Ala147Thrsubstitution in translocator protein is associated with adult separation anxiety in patients with depression 205
The Spontaneous Ala147Thr Amino Acid Substitution within the Translocator Protein Influences Pregnenolone Production in Lymphomonocytes of Healthy Individuals 205
Translocator protein (tspo) ligand residence time: a new parameter to predict neurosteroidogenic efficacy for n,n-dialkyl-2-arylindol-3-ylglyoxylamides (PIGAs) 205
Benzodiazepine receptor ligands. 8: Synthesis and pharmacological evaluation of new pyrazolo[5,1-c] [1,2,4]benzotriazine 5-oxide 3- and 8-disubstituted: High affinity ligands endowed with inverse-agonist pharmacological efficacy 203
Sex Differences in Blood Accumulation of Neurodegenerative-Related Proteins and Antioxidant Responses to Regular Physical Exercise 201
Human glioblastoma multiforme: p53 reactivation by a novel MDM2 inhibitor 201
Negative effects of a high tumour necrosis factor-α concentration on human gingival mesenchymal stem cell trophism: The use of natural compounds as modulatory agents 201
The Anxiolytic Etifoxine Binds to TSPO Ro5-4864 Binding Site with Long Residence Time Showing a High Neurosteroidogenic Activity 200
Evaluation of 2,3,4,8,13a hexahydro-1H-benzo[5,6]cyclohepta-6,7-dihydroxy[1,2,3-ef][3]benzazepine derivatives as dopamine receptor ligands 197
The human microglial surveillant phenotype is preserved by de novo neurosteroidogenesis through the control of cholesterol homeostasis: Crucial role of 18 kDa Translocator Protein 195
2,3-butanedione inactivates the [H-3]nitrendipine binding sites, whereas diethylpyrocarbonate does not 195
An irreversible ligand of the 18 kDa Translocator Protein induces rapidly ΔΨm collapse and activates apoptosis in human glioblastoma multiforme cells. 195
Discovery of the First-in-Class Dual TSPO/Carbonic Anhydrase Modulators with Promising Neurotrophic Activity 195
Translocator Protein (TSPO) and Neurosteroids: Implications in Psychiatric Disorders. 192
Targeting the 18-kDa translocator protein: Recent perspectives for neuroprotection 192
Reductions in platelet 18-kDa translocator protein density are associated with adult separation anxiety in patients with bipolar disorder 191
Translocator protein and steroidogenesis 190
Role of Translocator Protein (18 kDa) in Adult Separation Anxiety and Attachment Style in Patients with Depression. 189
Peripheral benzodiazepine receptor: characterization in human T-lymphoma Jurkat cells 187
Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene)sulfonamido-based hydroxamates as matrix metalloproteinase inhibitors 187
De novo neurosteroidogenesis in human microglia: Involvement of the 18 kda translocator protein 185
DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterization 183
Antitumoral effect by induction of collapse of mitochondrial membrane potential in Glioblastoma Multiforme cells 183
Relazione tra densità del recttore periferico delle benzodiazepine (PBR) e tumorogenicità delle cellule di glioma: produzione di linee cellulari ingegnerizzate a sovraesprimere il PBR 183
Synthesis and Biological Evaluation of 4-Phenylquinazoline-2-carboxamides Designed as a Novel Class of Potent Ligands of the Translocator Protein 181
C-Nucleoside analogues of furanfurin as ligands to A1 adenosine receptors 179
Carbonic anhydrase activation profile of indole-based derivatives 179
The relationship of separation anxiety with the age of onset of panic disorder 178
Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: Stimulation of in vitro neurosteroid production affecting GABA(A) receptor activity 178
Microglial pro-inflammatory and anti-inflammatory phenotypes are modulated by translocator protein activation 178
Chemical modification of the dihydropyridines binding sites by lysine reagent, pyridoxal 5’-phosphate 177
Translocator protein (TSPO) and identification of new molecular diagnosis tools 176
Benzodiazepine receptor ligands. 7. Synthesis and pharmacological evaluation of new 3-esters of the 8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide. 3-(2-Thienylmethoxycarbonyl) derivative: an anxioselective agent in rodents 176
Exploiting the 4-Phenylquinazoline Scaffold for the Development of High Affinity Fluorescent Probes for the Translocator Protein (TSPO) 176
Unbinding of Translocator Protein 18 kDa (TSPO) Ligands: From in Vitro Residence Time to in Vivo Efficacy via in Silico Simulations 176
PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a new mitochondrial benzodiazepine-receptor ligand, induces apoptosis in C6 glioma cells 175
2-Arylpyrazolo[1,5-a]pyrimidin-3-yl acetamides. New potent and selective peripheral benzodiazepine receptor ligands 175
A2A adenosine receptor: solubilization from bovine striatal membranes by digitonin detergent. 174
Serotonin: a signaling molecule during embryonal development of the amphibian Xenopus laevis 174
Oxytocin receptor polymorphisms and adult attachment style in patients with depression 174
Powerful twin carboxylic inhibitors for MMP homodimerization 174
Compounds with a benzo [a]carbazole structure for use in the prevention and/or treatment of infectious diseases 173
null 173
Bioisosterism, enantioselectivity and molecular modeling of new effective N6- and/or N(9)-substituted 2-phenyl adenines and 8-aza analogs: different binding modes to A1 adenosine receptors 173
Benzodiazepine receptor ligands-Part II. Synthesis and biological evaluation of pyrazolo[5,1-c][1,2,4]benzotriazine 4-oxide 173
Regular exercise delays microvascular endothelial dysfunction by regulating antioxidant capacity and cellular metabolism 172
A2A adenosine receptors and cytokines: modulation of apoptosis in PC12 cells 171
N,N-Dialkyl-2-phenylindol-3- ylglyoxylamides. A New Class of Potent and Selective Ligands at the Peripheral Benzodiazepine Receptor 170
Synthesis, biological evaluation, and molecular modeling of ribose-modified adenosine analogues as adenosine receptor agonists 170
PK 11195 differentially affects cell survival in human wild-type and 18 kDa translocator protein-silenced ADF astrocytoma cells 170
Tertiary amides with a five-membered heteroaromatic ring as new probes for the translocator protein 169
A 2-phenylindol-3-ylglyoxylammide derivative, a new-synthesized peripheral benzodiazepine receptor ligand, induces apoptosis in rat C6 glioma cells 169
The peripheral-type benzodiazepine receptor ligand PK 11195 induces mitochondrial permeability transition and apoptosis in human healthy lymphocytes 168
Refinement of the translocator protein pharmacophore/receptor model via structure-activity relationships of novel N,N-dialkylindolylglyoxylamides 168
Characterization of a voltage-dependent L-type calcium channel from rabbit and turtle brain 168
18-kDa translocator protein association complexes in the brain: From structure to function 168
Oxytocin receptor polymorphisms and adult attachment style in patients with depression 166
Insight into 2-phenylpyrazolo[1,5-a]pyrimidin-3-yl acetamides as peripheral benzodiazepine receptor ligands: synthesis, biological evaluation and 3D-QSAR investigation 165
Interaction of the irreversible ligand IRDE-MPIGA with TSPO (18 KDa): new insight on TSPO role in tumor cells. 165
Serotonin: a signalling molecule during embryonal development of the amphibian Xenopus laevis 164
Synthesis and benzodiazepine receptor binding activity of 2, 9-disubstituted quinolino[2', 3'-5, 4](3-pyrazolino)[3, 2-b]purin-4-ones 163
Targeting the Translocator Protein (18 kDa) in Cardiac Diseases: State of the Art and Future Opportunities 162
Characterization of a cloned xenopus laevis serotonin 5-HT1A receptor expressed in the NIH-3T3 cell line. 162
Structure-Activity Relationship Refinement and Further Assessment of 4-Phenylquinazoline-2-carboxamide Translocator Protein Ligands as Antiproliferative Agents in Human Glioblastoma Tumors. 162
pyrazolo [1,5-a]pyrimidines: new peripheral benzodiazepine receptor ligands 161
Totale 20.508
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Categoria #
all - tutte 85.036
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 85.036
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.672 0 0 0 101 341 259 83 92 52 37 114 593
2022/20232.673 323 301 162 286 310 356 22 230 469 11 167 36
2023/20241.881 195 181 199 105 248 336 60 97 34 76 104 246
2024/20255.527 52 219 54 322 538 573 349 277 584 768 584 1.207
2025/20266.452 503 757 713 376 612 606 1.278 307 365 534 250 151
2026/20272.720 228 1.076 1.413 3 0 0 0 0 0 0 0 0
Totale 31.750