GRANCHI, CARLOTTA
 Distribuzione geografica
Continente #
NA - Nord America 11.777
EU - Europa 5.965
AS - Asia 5.912
SA - Sud America 970
AF - Africa 293
OC - Oceania 26
Continente sconosciuto - Info sul continente non disponibili 6
Totale 24.949
Nazione #
US - Stati Uniti d'America 11.379
IT - Italia 2.920
SG - Singapore 1.844
CN - Cina 1.567
HK - Hong Kong 849
BR - Brasile 806
SE - Svezia 613
VN - Vietnam 502
DE - Germania 480
FR - Francia 375
BG - Bulgaria 317
GB - Regno Unito 300
CA - Canada 284
IN - India 241
FI - Finlandia 224
TR - Turchia 201
RU - Federazione Russa 181
KR - Corea 157
JP - Giappone 140
AT - Austria 134
NL - Olanda 84
UA - Ucraina 71
AR - Argentina 67
BD - Bangladesh 63
MX - Messico 57
BE - Belgio 53
CI - Costa d'Avorio 47
IQ - Iraq 47
ZA - Sudafrica 44
PL - Polonia 40
CH - Svizzera 37
ES - Italia 36
MA - Marocco 36
NG - Nigeria 31
PK - Pakistan 31
UZ - Uzbekistan 30
EG - Egitto 28
SN - Senegal 28
EC - Ecuador 27
SA - Arabia Saudita 27
ID - Indonesia 26
AU - Australia 24
CO - Colombia 20
IR - Iran 20
TW - Taiwan 20
VE - Venezuela 20
IL - Israele 19
CZ - Repubblica Ceca 16
TN - Tunisia 15
IE - Irlanda 14
DZ - Algeria 12
KE - Kenya 12
PH - Filippine 12
CL - Cile 11
MY - Malesia 11
NP - Nepal 11
AE - Emirati Arabi Uniti 10
RO - Romania 10
AZ - Azerbaigian 9
JO - Giordania 9
GH - Ghana 8
HU - Ungheria 8
JM - Giamaica 8
LT - Lituania 8
PY - Paraguay 8
AO - Angola 7
CR - Costa Rica 7
DK - Danimarca 7
DO - Repubblica Dominicana 7
ET - Etiopia 7
LB - Libano 7
OM - Oman 7
PA - Panama 7
PT - Portogallo 7
TH - Thailandia 7
TT - Trinidad e Tobago 7
QA - Qatar 6
AL - Albania 5
HN - Honduras 5
KW - Kuwait 5
KZ - Kazakistan 5
AM - Armenia 4
BY - Bielorussia 4
GR - Grecia 4
KG - Kirghizistan 4
PE - Perù 4
SK - Slovacchia (Repubblica Slovacca) 4
UY - Uruguay 4
BJ - Benin 3
CU - Cuba 3
GE - Georgia 3
LA - Repubblica Popolare Democratica del Laos 3
LY - Libia 3
MO - Macao, regione amministrativa speciale della Cina 3
RS - Serbia 3
BA - Bosnia-Erzegovina 2
BB - Barbados 2
BO - Bolivia 2
EU - Europa 2
GA - Gabon 2
Totale 24.901
Città #
Ashburn 1.176
Singapore 1.065
Serra 970
Woodbridge 961
Fairfield 839
Hong Kong 831
Dallas 777
San Jose 756
Ann Arbor 626
Houston 604
Chandler 581
Santa Clara 527
Seattle 361
Shanghai 332
Beijing 320
Sofia 317
Wilmington 294
Cambridge 292
New York 253
Milan 232
Los Angeles 208
Hefei 199
Boardman 184
Pisa 164
Princeton 162
Ottawa 154
Council Bluffs 150
Lauterbourg 128
Florence 123
Seoul 123
Ho Chi Minh City 117
Vienna 115
Lawrence 114
Tokyo 112
Helsinki 110
Medford 107
Munich 101
Izmir 99
Rome 98
London 94
Marseille 89
Hanoi 86
Nanjing 84
Des Moines 81
Dearborn 76
Redondo Beach 69
Jacksonville 68
Boulder 66
Istanbul 64
Redwood City 64
São Paulo 62
Dong Ket 59
Lucca 58
Frankfurt am Main 55
Livorno 53
Abidjan 46
Orem 43
Buffalo 42
Columbus 41
Chicago 40
Hyderabad 40
Ogden 39
San Diego 38
The Dalles 35
Turku 35
Lagos 31
Nanchang 31
Mumbai 30
Turin 30
Belo Horizonte 29
Bologna 28
Dakar 28
San Francisco 28
Brussels 27
Rio de Janeiro 27
Amsterdam 26
Chennai 25
Denver 25
Kunming 24
Phoenix 24
Mexico City 22
Warsaw 22
Washington 22
Düsseldorf 21
Montreal 21
Tashkent 21
Baltimore 20
Manchester 20
Nuremberg 20
Vicopisano 20
Zurich 20
Baghdad 19
Casablanca 19
Hangzhou 19
Toronto 19
Ankara 18
Guangzhou 18
Atlanta 17
Dhaka 17
Johannesburg 17
Totale 17.014
Nome #
COMPOSTO INIBITORE DELL’ENZIMA LATTATO DEIDROGENASI (LDH) E COMPOSIZIONE FARMACEUTICA CHE COMPRENDE TALE COMPOSTO 362
4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors 330
Glycoconjugated metal complexes as cancer diagnostic and therapeutic agents 315
GLUT1 and LOX inhibitors as perspective anticancer agents tackling glucose avidity and ECM remodeling in tumors 272
Phenylpropanoids and flavonoids from Phlomis kurdica as inhibitors of human lactate dehydrogenase. 265
Receptor-based virtual screening evaluation for the identification of estrogen receptor β ligands 260
New activators of SIRT1 enzyme for the treatment of cardiovascular and cardiometabolic pathologies 249
Synthesis and biological evaluation of non-glucose glycoconjugated N-hydroyxindole class LDH inhibitors as anticancer agents 238
Identification of Lactate Dehydrogenase 5 Inhibitors using Pharmacophore- Driven Consensus Docking 234
Sonde diagnostiche per evidenziare all’infrarosso cellule e tessuti affetti da condizioni patologiche o metaboliche 232
Synthesis and Biological Evaluation of New Glycoconjugated LDH Inhibitors as Anticancer Agents 230
Nuovi attivatori dell’enzima SIRT1 per il trattamento delle patologie cardiovascolari e cardiometaboliche 224
First examples of H2S-releasing glycoconjugates: stereoselective synthesis and anticancer activities 222
Structural optimization of 4-chlorobenzoylpiperidine derivatives for the development of potent, reversible and selective monoacylglycerol lipase (MAGL) inhibitors 220
Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors 220
A Virtual Screening Study for Lactate Dehydrogenase 5 Inhibitors by using a Pharmacophore-Based Approach 219
Glucose transporters: production, crystallization and inhibition 219
Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor 218
Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors 216
Diagnostic probes to detect cells and tissues afflicted with a pathological or metabolic condition by means of infrared spectroscopy 211
Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors 210
Rational Development of MAGL Inhibitors 210
Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death 208
Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors 203
Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials 203
Historical perspective of tumor glycolysis: a century with Otto Warburg 200
Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform a (LDH-A) as Starvation Agents against Cancer Cells 200
Dual Targeting of the Warburg Effect with a Glucose-Conjugated Lactate Dehydrogenase Inhibitor 200
COMPOUNDS INHIBITING THE ENZYME LACTATE DEHYDROGENASE (LDH), PHARMACEUTICAL COMPOSITIONS AND USES THEREOF 200
ATP citrate lyase (ACLY) inhibitors: An anti-cancer strategy at the crossroads of glucose and lipid metabolism 199
Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors 198
Reactive Oxygen Species Synergize to Potently and Selectively Induce Cancer Cell Death 198
Antiproliferative oxime derivatives that inhibit glucose transporter 1 (GLUT1) in cancer cells 197
Identification of new FYN kinase inhibitors using a FLAP-based approach 197
Characterization of the Saffron Derivative Crocetin as an Inhibitor of Human Lactate Dehydrogenase 5 in the Antiglycolytic Approach against Cancer 195
Anticancer agents interacting with membrane glucose transporters 194
Risks and Benefits Related to Alimentary Exposure to Xenoestrogens 194
An Update on Patents Covering Agents That Interfere with the Cancer Glycolytic Cascade 193
Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors 193
Functionalized aliphatic polyketones with germicide activity 193
Hypoxia-activated lysyl oxidase (LOX) inhibitors in the treatment of highly invasive and metastatic cancer 191
Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer 191
Phenylethanoid glycosides from Cistanche phelypaea acting as monoacylglycerol lipase inhibitors 190
Estrogen receptor ligands: a patent review update 188
Nuovi agenti antivirali a struttura N-idrossiindrol-carbossamidica 186
Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model 186
Cyclic Ketoximes as Estrogen Receptorβ Selective Agonists 185
Anticancer Agents That Counteract Tumor Glycolysis 183
An update on therapeutic opportunities offered by cancer glycolytic metabolism 183
Design, Synthesis, and Evaluation of GLUT Inhibitors 183
Liposomal delivery of a Pin1 inhibitor complexed with cyclodextrins as new therapy for high-grade serous ovarian cancer 183
Selective and potent agonists for estrogen receptor beta derived from molecular refinements of salicylaldoximes 182
Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds 181
Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways 181
Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia 180
N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation 179
VenomPred 2.0: A Novel In Silico Platform for an Extended and Human Interpretable Toxicological Profiling of Small Molecules 176
Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives 175
Clerodanes from Salvia pseudorosmarinus and their activity as inhibitors of monoacylglycerol lipase (MAGL) 175
Oxime-based inhibitors of glucose transporter 1 displaying antiproliferative effects in cancer cells 174
Natural compounds as inhibitors of lactate dehydrogenase 173
Synthesis of sulfonamide-containing N-hydroxyindole-2-carboxylates as inhibitors of human lactate dehydrogenase-isoform 5 172
Salicylketoximes as inhibitors of Glucose Transporters 172
Salicylketoximes that target glucose transporter 1 restrict energy supply to lung cancer cells 172
Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors 170
Preclinical emergence of novel lactate dehydrogenase inhibitors as potent antitumor agents in hypoxic models of pancreatic cancer: molecular mechanisms underlying their synergistic interaction with gemcitabine 168
Biphenyl-Derivatives Possessing Tertiary Amino Groups as ß-Secretase (BACE1) Inhibitors 168
Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors 167
The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: Interplay with the complex tumor microenvironment and novel therapeutic strategies 166
Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia. 166
BACE1 inhibitory activities of enantiomerically pure, variously substituted N-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl) arylsulfonamides 165
Bioactive heterocycles containing endocyclic N-hydroxy groups 165
Triazole-substituted N-hydroxyindol-2-carboxylates as inhibitors of isoform 5 of human lactate dehydrogenase (hLDH5) 164
Effect of Tumor Relevant Acidic Environment in the Interaction of a N-hydroxyindole-2-Carboxylic Derivative with the Phospholipid Bilayer 163
Nuovi inibitori reversibili della monoacilglicerolo lipasi (MAGL) quali potenziali agenti antitumorali, antiinfiammatori e neuroprotettivi. 163
N-Hydoxyindoles: novel, selective, and efficient inhibitors of isoform 5 of human lactate dehydrogenase (hLDH-5) 162
Small-molecule inhibitors of human LDH5 160
Combined inhibition of pyruvate dehydrogenase kinase 1 and lactate dehydrogenase a induces metabolic and signaling reprogramming and enhances lung adenocarcinoma cell killing 159
Abstract 3082: Targeting hypoxic pancreatic cancer cells with glucose conjugated lactate dehydrogenase inhibitor NHI-Glc-2 159
Application of MM-PBSA methods in virtual screening 158
Bioreductively Activated Lysyl Oxidase Inhibitors against Hypoxic Tumours 156
First-of-its-kind STARD 3 Inhibitor: In Silico Identification and Biological Evaluation as Anticancer Agent 155
Synergistic Interaction of Novel Lactate Dehydrogenase Inhibitors with Gemcitabine in Hypoxic Models of Pancreatic Cancer 154
AGENTI TERAPEUTICI IN GRADO DI RIDURRE LA PRODUZIONE CELLULARE DI ACIDO LATTICO E COMPOSIZIONI FARMACEUTICHE CHE COMPRENDONO TALI COMPOSTI 154
Constituents of Polygala flavescens ssp. flavescens and their activity as inhibitors of human lactate dehydrogenase 154
A patent review of Monoacylglycerol Lipase (MAGL) inhibitors (2013-2017) 154
Carbazole-containing arylcarboxamides as BACE1 inhibitors 152
Activators of Sirtuin-1 and their Involvement in Cardioprotection 152
The Benzoylpiperidine Fragment as a Privileged Structure in Medicinal Chemistry: A Comprehensive Review 151
Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives 151
Metabolic Effects of New Glucose Transporter (GLUT-1) and Lactate Dehydrogenase-A (LDH-A) Inhibitors against Chemoresistant Malignant Mesothelioma 150
Development and validation of a docking-based virtual screening platform for the identification of new lactate dehydrogenase inhibitors 149
New phenylethanoid glycosides from Cistanche phelypaea and their activity as inhibitors of monoacylglycerol lipase (MAGL) 149
An updated patent review of monoacylglycerol lipase (MAGL) inhibitors (2018-present) 149
WaSPred: A reliable AI-based water solubility predictor for small molecules 147
Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds 147
Inhibitors of lactate dehydrogenase (hLDH5) from Polygala flavescens subsp. flavescens 146
Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies 146
First-in-Class Dual Targeting Compounds for the Management of Seizures in Glucose Transporter Type 1 Deficiency Syndrome 145
New diterpenes from Salvia pseudorosmarinus and their activity as inhibitors of monoacylglycerol lipase (MAGL) 144
Totale 18.910
Categoria #
all - tutte 67.404
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 67.404


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.769 88 114 57 103 229 274 72 100 62 76 94 500
2022/20232.120 231 291 169 173 234 281 33 155 355 19 144 35
2023/20241.536 129 122 127 96 203 251 113 67 31 54 116 227
2024/20255.199 69 182 147 281 419 502 400 264 496 605 624 1.210
2025/20266.836 373 818 919 688 605 526 997 333 519 502 378 178
2026/202725 25 0 0 0 0 0 0 0 0 0 0 0
Totale 25.420