MINUTOLO, FILIPPO
 Distribuzione geografica
Continente #
NA - Nord America 22.332
AS - Asia 10.562
EU - Europa 10.213
SA - Sud America 1.473
Continente sconosciuto - Info sul continente non disponibili 579
AF - Africa 403
OC - Oceania 40
Totale 45.602
Nazione #
US - Stati Uniti d'America 21.558
IT - Italia 4.470
SG - Singapore 3.236
CN - Cina 2.911
HK - Hong Kong 1.600
BR - Brasile 1.237
SE - Svezia 1.185
DE - Germania 1.005
VN - Vietnam 832
BG - Bulgaria 727
CA - Canada 607
TR - Turchia 594
FR - Francia 573
GB - Regno Unito 495
FI - Finlandia 434
IN - India 361
RU - Federazione Russa 335
UA - Ucraina 319
JP - Giappone 264
KR - Corea 196
CH - Svizzera 146
AT - Austria 108
NL - Olanda 88
BD - Bangladesh 87
BE - Belgio 78
AR - Argentina 73
CI - Costa d'Avorio 71
NG - Nigeria 71
MX - Messico 66
PL - Polonia 58
IQ - Iraq 56
ZA - Sudafrica 54
ES - Italia 53
ID - Indonesia 45
MA - Marocco 44
SA - Arabia Saudita 42
EC - Ecuador 39
PK - Pakistan 39
UZ - Uzbekistan 36
AU - Australia 32
VE - Venezuela 32
CO - Colombia 31
SN - Senegal 31
IR - Iran 25
EG - Egitto 23
IL - Israele 21
KE - Kenya 21
TN - Tunisia 20
CL - Cile 19
JO - Giordania 19
TW - Taiwan 18
IE - Irlanda 17
MY - Malesia 17
NP - Nepal 17
CZ - Repubblica Ceca 16
JM - Giamaica 16
RO - Romania 16
AZ - Azerbaigian 15
CR - Costa Rica 15
GR - Grecia 15
PH - Filippine 15
PY - Paraguay 15
AE - Emirati Arabi Uniti 13
DO - Repubblica Dominicana 13
OM - Oman 13
TT - Trinidad e Tobago 13
DK - Danimarca 12
DZ - Algeria 12
KZ - Kazakistan 12
GH - Ghana 11
LT - Lituania 11
MO - Macao, regione amministrativa speciale della Cina 11
UY - Uruguay 11
BJ - Benin 9
HU - Ungheria 9
PE - Perù 9
TH - Thailandia 9
BY - Bielorussia 8
ET - Etiopia 8
NZ - Nuova Zelanda 8
AL - Albania 6
AO - Angola 6
BA - Bosnia-Erzegovina 6
HN - Honduras 6
LB - Libano 6
LK - Sri Lanka 6
PA - Panama 6
PR - Porto Rico 6
PS - Palestinian Territory 6
BB - Barbados 5
NI - Nicaragua 5
RS - Serbia 5
AM - Armenia 4
BO - Bolivia 4
GE - Georgia 4
LA - Repubblica Popolare Democratica del Laos 4
PT - Portogallo 4
QA - Qatar 4
SV - El Salvador 4
SY - Repubblica araba siriana 4
Totale 44.952
Città #
Ashburn 2.274
Woodbridge 2.090
Singapore 1.870
Hong Kong 1.573
Ann Arbor 1.419
Fairfield 1.362
Chandler 1.349
Houston 1.248
Serra 1.211
San Jose 1.169
Dallas 951
Milan 911
Santa Clara 898
Sofia 727
Shanghai 634
Beijing 613
Seattle 554
Wilmington 505
New York 483
Cambridge 482
Ottawa 457
Jacksonville 400
Izmir 391
Boardman 349
Princeton 322
Los Angeles 289
Lawrence 275
Nanjing 261
Lauterbourg 257
Medford 257
Hefei 246
Council Bluffs 245
Tokyo 217
Ho Chi Minh City 193
Rome 183
Pisa 177
Seoul 167
Des Moines 148
Helsinki 148
Dearborn 146
Istanbul 141
Florence 139
Dong Ket 136
Hanoi 127
Bern 122
Redondo Beach 121
London 119
Redwood City 119
Marseille 111
Nanchang 111
Boulder 110
Munich 105
Buffalo 100
São Paulo 88
Vienna 87
San Diego 80
Columbus 71
Abidjan 69
Frankfurt am Main 69
Lagos 69
The Dalles 68
Orem 67
Jüchen 60
Livorno 57
Ogden 56
Chicago 52
Lucca 49
Shenyang 49
Brussels 48
Hyderabad 48
San Francisco 48
Hebei 46
Kunming 46
Pune 46
Mumbai 45
Washington 45
Guangzhou 41
Chennai 40
Turku 40
Tianjin 39
Belo Horizonte 38
Nürnberg 37
Phoenix 37
Atlanta 36
Warsaw 36
Norwalk 35
Rio de Janeiro 35
Jiaxing 33
Hangzhou 32
Dakar 31
Nuremberg 30
Toronto 30
Turin 29
Amsterdam 28
Auburn Hills 28
Changsha 28
Bologna 27
Da Nang 27
Denver 27
Jinan 26
Totale 31.165
Nome #
First examples of H2S-releasing glycoconjugates: stereoselective synthesis and anticancer activities 384
Diagnostic probes to detect cells and tissues afflicted with a pathological or metabolic condition by means of infrared spectroscopy 383
COMPOSTO INIBITORE DELL’ENZIMA LATTATO DEIDROGENASI (LDH) E COMPOSIZIONE FARMACEUTICA CHE COMPRENDE TALE COMPOSTO 362
Anticancer agents interacting with membrane glucose transporters 359
4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors 332
Glycoconjugated metal complexes as cancer diagnostic and therapeutic agents 317
GLUT1 and LOX inhibitors as perspective anticancer agents tackling glucose avidity and ECM remodeling in tumors 274
Phenylpropanoids and flavonoids from Phlomis kurdica as inhibitors of human lactate dehydrogenase. 265
Receptor-based virtual screening evaluation for the identification of estrogen receptor β ligands 260
New activators of SIRT1 enzyme for the treatment of cardiovascular and cardiometabolic pathologies 253
Synthesis and biological evaluation of non-glucose glycoconjugated N-hydroyxindole class LDH inhibitors as anticancer agents 239
Identification of Lactate Dehydrogenase 5 Inhibitors using Pharmacophore- Driven Consensus Docking 236
Sonde diagnostiche per evidenziare all’infrarosso cellule e tessuti affetti da condizioni patologiche o metaboliche 232
Synthesis and Biological Evaluation of New Glycoconjugated LDH Inhibitors as Anticancer Agents 230
Nuovi attivatori dell’enzima SIRT1 per il trattamento delle patologie cardiovascolari e cardiometaboliche 225
Glucose transporters: production, crystallization and inhibition 223
Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor 222
New NO-Releasing Pharmacodynamic Hybrids of Losartan and Its Active Metabolite: Design,Synthesis, and Biopharmacological Properties 221
Structural optimization of 4-chlorobenzoylpiperidine derivatives for the development of potent, reversible and selective monoacylglycerol lipase (MAGL) inhibitors 221
Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors 221
A Virtual Screening Study for Lactate Dehydrogenase 5 Inhibitors by using a Pharmacophore-Based Approach 220
Sirtuin 1-Activating Compounds: Discovery of a Class of Thiazole-Based Derivatives 217
Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors 217
Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors 213
Rational Development of MAGL Inhibitors 211
Synthesis of Anthranylaldoxime Derivatives as Estrogen Receptor Ligands and Computational Prediction of Binding Modes 209
Lactate dehydrogenase-A inhibition induces human glioblastoma multiforme stem cell differentiation and death 208
A role for lactate dehydrogenase in the c-Met/HGF signaling axis 207
A Convenient Three-Component Synthesis of Substituted Cyclopentadienyl Tricarbonyl Rhenium Complexes 205
Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors 204
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 204
Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials 204
Historical perspective of tumor glycolysis: a century with Otto Warburg 203
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 203
Synthesis of stable analogues of geranylgeranyl diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition 203
Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors 202
Identification of new FYN kinase inhibitors using a FLAP-based approach 202
Tackling tumors by exploiting their glucose avidity and high rate of glycolysis 201
Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform a (LDH-A) as Starvation Agents against Cancer Cells 200
Dual Targeting of the Warburg Effect with a Glucose-Conjugated Lactate Dehydrogenase Inhibitor 200
COMPOUNDS INHIBITING THE ENZYME LACTATE DEHYDROGENASE (LDH), PHARMACEUTICAL COMPOSITIONS AND USES THEREOF 200
Reactive Oxygen Species Synergize to Potently and Selectively Induce Cancer Cell Death 199
Antiproliferative oxime derivatives that inhibit glucose transporter 1 (GLUT1) in cancer cells 198
Characterization of the Saffron Derivative Crocetin as an Inhibitor of Human Lactate Dehydrogenase 5 in the Antiglycolytic Approach against Cancer 197
Synthesis and dopaminergic properties of the two enantiomers of 3-(3,4-dimethylphenyl)-1-propylpiperidine, a potent and selective dopamine D4 receptor ligand 195
METAL SALT-PROMOTED ALDOL REACTION OF SILYL ENOL ETHERS WITH ALDEHYDES 195
Phosphonomethylphosphorylmethyl(oxy)-analogues of geranylgeranyl diphosphate as stable and selective geranylgeranyl protein transferase inhibitors 195
Functionalized aliphatic polyketones with germicide activity 195
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors 194
Risks and Benefits Related to Alimentary Exposure to Xenoestrogens 194
Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors 194
A Polymer-Supported Phosphazine as a Stable and Practical Reagent in the Three-Component Synthesis of Substituted (Cyclopentadienyl)tricarbonylrhenium Complexes 193
Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies 193
An Update on Patents Covering Agents That Interfere with the Cancer Glycolytic Cascade 193
4-[6-(dansylamino)hexylamino]-7-methyl-2-phenyl-1,8-naphthyridine as a new potential fluorescent probe for studying A1-adenosine receptor 193
Hypoxia-activated lysyl oxidase (LOX) inhibitors in the treatment of highly invasive and metastatic cancer 191
CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides 191
Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer 191
Estrogen receptor ligands: a patent review update 189
Nuovi agenti antivirali a struttura N-idrossiindrol-carbossamidica 188
Liposomal delivery of a Pin1 inhibitor complexed with cyclodextrins as new therapy for high-grade serous ovarian cancer 187
Pharmacological study on the cardiovascular activity of no-sartans, pharmacodynamic hybridsexhibiting at1-antagonist and no-donor properties 186
Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model 186
Cyclic Ketoximes as Estrogen Receptorβ Selective Agonists 186
Spirocyclic Benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel 186
Design, Synthesis, and Evaluation of GLUT Inhibitors 185
Anticancer Agents That Counteract Tumor Glycolysis 183
QSAR models for predicting enzymatic hydrolysis of new chemical entities in 'soft-drug' design 183
An update on therapeutic opportunities offered by cancer glycolytic metabolism 183
Variously substituted (phosphonoacetamido)oxy analogues of geranylgeranyl diphosphate (GGdP) as GGdP-transferase (GGTase) inhibitors and antiproliferative agents 183
Boronic Acids in the Three-Component Synthesis of Carbon-Substituted Cyclopentadienyl Tricarbonyl Rhenium Complexes 182
Selective and potent agonists for estrogen receptor beta derived from molecular refinements of salicylaldoximes 182
Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds 182
Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways 182
N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation 181
Diaryl-substituted salicyl- and anthranyl-ketoximes as potential estrogen receptor ligands 180
7-Nitrobenzofurazan (NBD)-Derivatives Of 5'-N-Ethylcarboxamidoadenosine (NECA) As New Fluorescent Probes For Human A3 Adenosine Receptors 180
Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia 180
New Benzopyran-Based Openers of the Mitochondrial ATP-Sensitive Potassium Channel with Potent Anti-Ischemic Properties 179
Selective activators of estrogen receptor beta based on the aldoxime and ketoxime scaffolds 178
Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives 176
NO-Sartans: A New Class of Pharmacodynamic Hybrids as Cardiovascular Drugs 176
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2) 176
Curaxins: A New Family of Non-genotoxic Multitargeted Anticancer Agents 176
Synthesis of sulfonamide-containing N-hydroxyindole-2-carboxylates as inhibitors of human lactate dehydrogenase-isoform 5 175
Salicylketoximes as inhibitors of Glucose Transporters 175
Radiosensitizing potentialof small organic molecules toward hypoxic tumor cells in the radiotherapy 174
Natural compounds as inhibitors of lactate dehydrogenase 174
Synthesis of aniline-type analogues of farnesyl diphosphate and their biological assays for prenyl protein transferase inhibitory activity 174
Oxime-based inhibitors of glucose transporter 1 displaying antiproliferative effects in cancer cells 174
a) Analgesici "pesanti": i Dramadoli; b) Ombrelli molecolari 173
Drug-likeness of multiple-binding drugs 173
Salicylketoximes that target glucose transporter 1 restrict energy supply to lung cancer cells 172
Preclinical emergence of novel lactate dehydrogenase inhibitors as potent antitumor agents in hypoxic models of pancreatic cancer: molecular mechanisms underlying their synergistic interaction with gemcitabine 171
Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors 171
Biphenyl-Derivatives Possessing Tertiary Amino Groups as ß-Secretase (BACE1) Inhibitors 169
Synthesis of a Resveratrol Analogue with High Ceramide-Mediated Proapoptotic Activity on Human Breast Cancer Cells 168
New N-n-propyl-substituted 3-Aryl and 3-Cyclohexyl piperidines as partial agonists at the D4 dopamine receptor 167
The dichotomous role of the glycolytic metabolism pathway in cancer metastasis: Interplay with the complex tumor microenvironment and novel therapeutic strategies 167
BACE1 inhibitory activities of enantiomerically pure, variously substituted N-(3-(4-benzhydrylpiperazin-1-yl)-2-hydroxypropyl) arylsulfonamides 166
Totale 20.571
Categoria #
all - tutte 124.490
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 124.490


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20223.285 0 293 80 199 521 490 129 194 84 120 180 995
2022/20233.837 489 497 260 395 467 506 41 296 606 29 205 46
2023/20243.378 446 423 353 261 486 585 126 102 57 74 121 344
2024/20258.764 84 391 254 525 671 784 644 498 927 1.167 932 1.887
2025/20269.629 527 1.164 1.130 741 846 926 1.585 482 701 862 447 218
2026/2027914 330 584 0 0 0 0 0 0 0 0 0 0
Totale 45.602