CINECA IRIS Institutional Research Information System

SIMORINI, FRANCESCA
 Distribuzione geografica
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Continente #
NA - Nord America 7.326
EU - Europa 3.867
AS - Asia 2.782
SA - Sud America 395
AF - Africa 154
OC - Oceania 26
Continente sconosciuto - Info sul continente non disponibili 1
Totale 14.551
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Nazione #
US - Stati Uniti d'America 7.098
IT - Italia 1.504
CN - Cina 917
SE - Svezia 770
SG - Singapore 615
DE - Germania 432
HK - Hong Kong 426
BR - Brasile 336
TR - Turchia 327
BG - Bulgaria 274
GB - Regno Unito 233
CA - Canada 196
VN - Vietnam 173
UA - Ucraina 134
RU - Federazione Russa 131
FI - Finlandia 130
IN - India 106
AT - Austria 79
CI - Costa d'Avorio 57
CH - Svizzera 44
JP - Giappone 43
FR - Francia 38
NG - Nigeria 32
AU - Australia 24
BD - Bangladesh 24
BE - Belgio 23
PK - Pakistan 18
NL - Olanda 17
IQ - Iraq 16
KR - Corea 16
SA - Arabia Saudita 16
MX - Messico 15
AR - Argentina 14
VE - Venezuela 14
SN - Senegal 13
EG - Egitto 12
CO - Colombia 10
UZ - Uzbekistan 10
IE - Irlanda 9
KE - Kenya 9
MY - Malesia 9
AZ - Azerbaigian 8
ES - Italia 8
JO - Giordania 8
ZA - Sudafrica 8
PE - Perù 7
PL - Polonia 7
CZ - Repubblica Ceca 6
ID - Indonesia 5
KZ - Kazakistan 5
LB - Libano 5
LT - Lituania 5
OM - Oman 5
TW - Taiwan 5
AL - Albania 4
DK - Danimarca 4
EC - Ecuador 4
ET - Etiopia 4
IR - Iran 4
JM - Giamaica 4
MA - Marocco 4
PY - Paraguay 4
BJ - Benin 3
DZ - Algeria 3
QA - Qatar 3
TT - Trinidad e Tobago 3
AE - Emirati Arabi Uniti 2
CL - Cile 2
CY - Cipro 2
GR - Grecia 2
HU - Ungheria 2
IL - Israele 2
KH - Cambogia 2
NZ - Nuova Zelanda 2
PA - Panama 2
PH - Filippine 2
PS - Palestinian Territory 2
PT - Portogallo 2
SO - Somalia 2
UY - Uruguay 2
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BN - Brunei Darussalam 1
BO - Bolivia 1
CR - Costa Rica 1
DO - Repubblica Dominicana 1
EE - Estonia 1
EU - Europa 1
GA - Gabon 1
GE - Georgia 1
GL - Groenlandia 1
HN - Honduras 1
HR - Croazia 1
KW - Kuwait 1
LC - Santa Lucia 1
LR - Liberia 1
LU - Lussemburgo 1
LY - Libia 1
MC - Monaco 1
Totale 14.538
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Città #
Woodbridge 920
Ann Arbor 847
Ashburn 688
Houston 688
Serra 564
Chandler 549
Santa Clara 467
Milan 444
Fairfield 437
Hong Kong 424
Singapore 299
Sofia 273
Izmir 261
Shanghai 223
Beijing 208
Jacksonville 195
Seattle 179
Ottawa 175
Wilmington 171
New York 158
Cambridge 147
London 128
Boardman 125
Princeton 121
Nanjing 111
Lawrence 110
Dong Ket 103
Los Angeles 92
Medford 79
Vienna 65
Frankfurt am Main 62
Des Moines 61
Hefei 61
Abidjan 57
Dearborn 56
Rome 54
Istanbul 53
Bern 43
Rho 38
Jüchen 32
Lagos 30
Kunming 29
Nanchang 29
Boulder 28
Bremen 28
Düsseldorf 28
Shenyang 27
Pune 26
Fuzhou 25
Munich 25
Redwood City 25
The Dalles 24
Brussels 23
Tokyo 23
Chicago 22
Ogden 22
Columbus 21
Changsha 20
San Diego 20
San Francisco 20
Nürnberg 19
Turku 19
Hebei 18
São Paulo 18
Pisa 15
Seoul 15
Tianjin 15
Washington 14
Aversa 13
Dakar 13
Florence 13
Sydney 13
Council Bluffs 12
Norwalk 12
Belo Horizonte 11
Toronto 11
Falls Church 10
Jiaxing 10
Orange 10
Porto Alegre 10
Dallas 9
Helsinki 9
Quanzhou 9
Secaucus 9
Tashkent 9
Amman 8
Auburn Hills 8
Dublin 8
Hangzhou 8
Lancaster 8
Melbourne 8
Osaka 8
Rio de Janeiro 8
Baku 7
Dhaka 7
Guangzhou 7
Hyderabad 7
New Delhi 7
Amsterdam 6
Brno 6
Totale 10.690
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Nome #
1,2-Benzisothiazole Derivatives Bearing 4-, 5-, or 6-Alkyl/arylcarboxamide Moieties Inhibit Carbonic Anhydrase Isoform IX (CAIX) and Cell Proliferation under Hypoxic Conditions 362
Benzofuroxane Derivatives as Multi Effective Agents for the Treatment of Cardiovascular Diabetic Complications. Synthesis, Functional Evaluation, and Molecular Modeling Studies 243
N, N-Dialkyl-2-phenylindol-3-ylglyoxylamides.A new class of potent and selective ligands at the Peripheral benzodiazepine receptor 241
Exploiting the Pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors, 217
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: a New Class of Selective Aldose Reductase Inhibitors 209
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: A New Class of Selective Aldose Reductase Inhibitors 199
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 198
TSPO-ligands prevent oxidative damage and inflammatory response in C6 glioma cells by neurosteroid synthesis 190
Identification of Anxiolytic/Nonsedative Agents among Indol-3-ylglyoxylamides Acting as Functionally Selective Agonists at the γ-Aminobutyric Acid-A (GABAA) α2 Benzodiazepine Receptor 188
5-Amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a Versatile Scaffold to Obtain Potent and Selective A3 Adenosine Receptor Antagonists 178
Geometrically Constrained Analogues N-Benzylindolylglyoxylylamides: [1,2,4]Triazino[4,3-a]benzimidazol-4(10H)-one Derivatives as Potential New Ligands at the Benzodiazepine Receptor. 177
Benzothiopyranoindole-Based Antiproliferative Agents: Synthesis, Cytotoxicity, Nucleic Acids Interaction, and Topoisomerases Inhibition Properties. 176
Medicinal chemistry of indolylglyoxylamide TSPO high affinity ligands with anxiolytic-like effects 175
Synthesis of a Novel Purine-Containing Heterocyclic Ring System: 8,10-Dimethylindolo[2',3':5,6][1,2,4]triazino[4,3-f]purine-9,11(8H,10H,13H)dione 171
Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity 170
Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII 170
Refinement of Structure-activity Relationships of the Triazinobenzimidazole A1AR Antagonists 168
Benzo[d]isothiazoles and Matrix Metalloproteinases. Searching for Novel and Selective Inhibitors of MMP9 166
“Synthesis and antiproliferative evaluation of new substituted Benzothiopyrano[4,3-c] condensed ring systems” 165
Recent Advances in the Development of Dual Topoisomerase I and II Inhibitors as Anticancer Drugs 164
Novel N(2)-Substituted Pyrazolo[3,4-d]pyrimidine Adenosine A(3) Receptor Antagonists: Inhibition of A(3)-Mediated Human Glioblastoma Cell Proliferation (dagger) 162
FACILE SYNTHESIS OF 3-SUBSTITUTED[1,2,4]TRIAZINO[3,4-F]PURINE-4,6,8-TRIONE DERIVATIVES 162
Structure-Based Optimization of Tyrosine Kinase Inhibitor CLM3. Design, Synthesis, Functional Evaluation, and Molecular Modeling Studies. 162
Studies in search for selective ligands for GABAA/BzR receptor subtypes: synthesis and biological evaluation of 4'-modified N-(benzyl)indol-3-ylglyoxylamides 161
Novel Pyrazolo[3,4-d]pyrimidine Derivatives as ATP-competitive Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase 159
Novel Potent and Selective Human Adenosine A3 Receptor Antagonists Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis and Biological Evaluation 159
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of non-camptothecin Topoisomerase I (Top1) inhibitors 159
Novel, Highly Potent Aldose Reductase Inhibitors:Cyano(2-oxo-2,3-dihydroindol-3-yl)acetic Acid Derivatives 158
An approach to novel fused triazole or tetrazole derivatives starting from Benzimidazo[1,2-a]quinazoline-5(7H)-one and 5,7-Dihydro-5-oxopyrido[3',2':5,6]pyrimido[1,2-a]benzimidazole 157
Medicinal chemistry of indolylglyoxylamide GABAA/BzR high affinity ligands: identification of novel anxiolytic/non sedative agents 157
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A(2B) adenosine receptor antagonists 156
Investigation of new 2-aryl substituted Benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors targeting vascular endothelial growth factor receptor 2 155
Synthesis of novel pyrido[3',2':5,6]thiopyrano[3,2-b]indol-5(6H)-ones and 6H-pyrido[3',2':5,6]thiopyrano[4,3-b]quinolines,two new heterocyclic systems. 149
Translocator protein (tspo) ligand residence time: a new parameter to predict neurosteroidogenic efficacy for n,n-dialkyl-2-arylindol-3-ylglyoxylamides (PIGAs) 149
Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: Stimulation of in vitro neurosteroid production affecting GABA(A) receptor activity 146
Antitumoral effect by induction of collapse of mitochondrial membrane potential in Glioblastoma Multiforme cells 145
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: A Novel Template for the Design of Highly Selective A(2B) Adenosine Receptor Antagonists. 145
Synthesis of New Heterocyclic Ring Systems via [1,3,5]Triazino[1,2-a]benzimidazole Derivatives 144
Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands 144
Tertiary amides with a five-membered heteroaromatic ring as new probes for the translocator protein 142
Acetic acid aldose reductase inhibitors bearing a five-membered heterocyclic core with potent topical activity in a visual impairment rat model 142
Pyrazolo[3,4,-d]pyrimidine-4-one Derivatives as Novel and Potent Inhibitors of Adenosine Deaminase 138
PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a new mitochondrial benzodiazepine-receptor ligand, induces apoptosis in C6 glioma cells 138
Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases 138
New fluorescent probes for the pheripheral-type benzodiazepine receptor: synthesis and biological application 136
Small Molecules Containing the Benzo[d]isotiazole Ring System as Novel ATP-Competitive Inhibitors of Epidermal Growth Factor Receptor protein Tyrosine Kinase 136
Synthesis and Biological Evaluation of Pyrido[1,2-d]pyrimidin-4-one Derivatives as Novel Aldose Reductase Inhibitors Exhibiting Antioxidant Activity 136
Novel Aldose Reductase Acetic acid Inhibitors Bearing a Five Membered heterocyclic core 136
Naphtho[1,2-d]isothiazole Acetic Acid Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors 134
Microwave-assisted Suzuki Coupling in Aqueous Media: a Useful Tool for the Synthesis of 3-Arylindazole Derivatives 133
N,N-Dialkyl-2-phenylindol-3- ylglyoxylamides. A New Class of Potent and Selective Ligands at the Peripheral Benzodiazepine Receptor 132
Benzisothiazole-1,1-dioxide alkanoic acid derivatives as inhibitors of rat lens aldose reductase 131
Discovery of Pyrido[3′,2′:5,6]thiopyrano[4,3- d]pyrimidine-Based Antiproliferative Multikinase Inhibitors 131
Refinement of the Benzodiazepine Receptor Site Topology by Structure-Activity Relationships of New N-(Heteroarylmethyl)indol-3-ylglyoxylamides 129
Geometrically Constrained Derivatives of Indolylglyoxylamides as Ligands Binding the GABAA/BzR Complex. 129
Novel Antitumoral Pyrazolopyrimidines Based on Inhibition of Protein Tyrosine Kinase 128
Synthesis and Benzodiazepine Receptor Affinity of Derivatives of the New Tricyclic Heteroaromatic System Pyrido[3’,2’:5,6]thiopyrano[4,3-c]pyridazin-3(2H,5H)-one 128
Cell survival/death processes: Role of the mitochondrial Tranlocator Protein (TSPO) ligands 126
Novel Irreversible Fluorescent Probes Targeting the 18 kDa Translocator Protein: Synthesis and Biological Characterization 126
1-(PHENYLSULPHONAMIDO)-PYRAZOLE DERIVATIVES AS CARBONIC ANHYDRASE INHIBITORS. 125
Synthesis of pyrrolo[3,4-c]pyridine derivatives possessing an acid group and their in vitro and in vivo evaluation as aldose reductase inhibitors 124
EFFECTS OF TSPO-LIGANDS ON MITOCHONDRIAL VOLUME AND MITOCHONDRIAL MEMBRANE POTENTIAL 122
A 2-phenylindol-3-ylglyoxylammide derivative, a new-synthesized peripheral benzodiazepine receptor ligand, induces apoptosis in rat C6 glioma cells 122
Nuovi derivati acidi acetici quali potenti inibitori dell’Aldoso Reduttasi 121
New Fluorescent 2-Phenylindoleglyoxylamide Derivatives as Probes Targeting the Peripheral-Type Benzodiazepine Receptor: Design, Synthesis, and Biological Evaluation 120
Synthesis and biological evaluation of Modified 2-Phenylindol-3-ylglyoxylamides as good candidates for the development of radioligands for the visualization of peripheral benzodiazepine receptor 120
Exploiting the pyrazolo[3,4-d]pyrimidinone ring system as a useful template for the obtainment of potent adenosine deaminase inhibitors 119
Refinement of the translocator protein pharmacophore/receptor model via structure-activity relationships of novel N,N-dialkylindolylglyoxylamides 119
2-(phenylsulphonamido)-pyrazole derivatives as carbonic anhydrase inhibitors 119
Benzoxadiazole Derivatives: Atypical Inhibitors of Aldose Reductase 118
Pyridopyrimidinone Derivatives as Novel Therapeutic Agents for the Topic Treatment of Vessel Walls Subjected to Percutaneous Intervention 118
Novel Highly Potent Adenosine Deaminase Inhibitors Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis, Structure-Activity Relationships and Molecular Modeling Studies 118
Anxiolytic-like Effects of N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides by Modulation of Translocator Protein Promoting Neurosteroid Biosynthesis 117
Synthesis and local anaesthetic activity of some 7-amino-2-dialkylaminoalkylpyrrolo[3,4-c]pyridine derivatives 116
Acid derivatives of benzisothiazole-1,1-dioxide as inhibitors of rat lens aldose reductase 115
New oxazole and 1,2,4-oxadiazole derivatives as selective ligands at the Translocator Protein (TSPO) 115
2-Phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one derivatives as a new class of adenosine receptor antagonists 111
Design, Synthesis, and Biological Evaluation of 3-Arylindazole Acetic Acid Derivatives as Aldose Reductase Inhibitors 110
New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors 109
Novel, Highly Potent Adenosine Deaminase Inhibitors Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synhesis, Structure-Activity Relationships, and Molecular Modeling Studies 108
Design, synthesis, and biological evaluation of novel fluorescent probes targeting the Translocator Protein (18 kDa) (TSPO) 108
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of noncamptothecin Topoisomerase I (top1) inhibitors 106
Tricyclic Sulfonamides Incorporating Benzothiopyrano[4,3-c]pyrazole and Pyridothiopyrano[4,3-c]pyrazole Effectively Inhibit a- and ß-Carbonic Anhydrase: X-ray Crystallography and Solution Investigations on 15 Isoforms 105
Glioblastoma multiforme: antitumoral in vitro effect by induction of collapse of mitochondrial membrane potential 103
Novel Pyrazolopyrimidine Derivatives as Therapeutic Agents for the Treatment of Medullary Thyroid Carcinoma 102
NOVEL KINASE INHIBITORS IN THYROID CANCER TREATMENT: SYNTHESIS AND BIOLOGICAL EVALUATION 101
3-Aryl-1,2,4-triazino-4,3-abenzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists 101
N,N-dialkyl-2-phenylindol-3-ylglyoxylylamide derivatives: a new class of potent and selective "pheripheral-type" benzodiazepine receptor ligands 100
Synthesis and Antiproliferative Activity of New Aminoalkyl Substituted Benzothiopyranoindoles 99
Targeting the Translocator protein (TSPO) with 2-phenylindol-3-ylglyoxylamide derivatives 96
Substituted 2-Arylindolglyoxylamides as Potent Translocator Protein (18 kDa) TSPO ligands: Synthesis and Biological Evaluation 95
"Sintesi e attività antiproliferativa di sistemi Pirido[3’,2’:5,6]tiopirano[4,3-c]pirazolici 2-aril sostituiti" 94
2-PHENYL[1,2,3]TRIAZOLO[1,2-a]BENZOTRIAZIN-1-ONE DERIVATIVES AS A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS 94
Synthesis and biological evaluation on human glioblastoma cells of novel pyrazolo[3,4-d]pyrimidine adenosine A(3) receptor antagonists. 94
New antiproliferative agents derived from tricyclic 3,4-dihydrobenzo[4,5]imidazo[1,2-a][1,3,5]triazine scaffold: synthesis and pharmacological effects 93
Dialkylaminoalkylindolonaphthyridines as potential antitumor agents: synthesis, cytotoxicity and DNA binding properties 93
Progettazione e sintesi di nuovi derivati 2-fenilindol-3-ilgliossilamidici per un approfondimento delle relazioni struttura attività (SAR) di questa classe di ligandi potenti e selettivi per il PBR 91
Synthesis and in vitro Antiproliferative Activity of New Substituted Benzo[3',2':5,6]thiopyrano[4,3-d]pyrimidines 91
"Synthesis of new indolo[3,2-c][1,8]naphthyridine derivatives as antiproliferative agents" 90
Synthesis and biological evaluation on human glioblastoma cells of novel pyrazolo3,4-Dpyrimidine adenosine A3 receptor antagonists 86
Totale 13.933
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Categoria #
all - tutte 37.745
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 37.745
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021917 175 33 54 44 89 34 41 71 73 52 55 196
2021/20221.236 24 93 57 88 226 143 18 58 49 24 83 373
2022/20231.847 237 350 121 170 218 219 22 145 278 7 63 17
2023/20241.408 200 184 159 122 222 238 41 28 21 38 37 118
2024/20253.415 28 131 25 211 429 344 196 157 311 447 357 779
2025/2026161 161 0 0 0 0 0 0 0 0 0 0 0
Totale 14.747