CINECA IRIS Institutional Research Information System

SIMORINI, FRANCESCA
 Distribuzione geografica
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Continente #
NA - Nord America 8.692
AS - Asia 4.305
EU - Europa 4.140
SA - Sud America 489
AF - Africa 178
OC - Oceania 26
Continente sconosciuto - Info sul continente non disponibili 1
Totale 17.831
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Nazione #
US - Stati Uniti d'America 8.427
IT - Italia 1.528
SG - Singapore 1.249
CN - Cina 1.187
SE - Svezia 777
HK - Hong Kong 583
DE - Germania 448
VN - Vietnam 420
BR - Brasile 397
TR - Turchia 332
BG - Bulgaria 275
GB - Regno Unito 257
CA - Canada 214
FI - Finlandia 175
FR - Francia 155
UA - Ucraina 139
IN - India 136
RU - Federazione Russa 135
JP - Giappone 92
AT - Austria 80
KR - Corea 72
CI - Costa d'Avorio 57
CH - Svizzera 50
BD - Bangladesh 34
NG - Nigeria 33
IQ - Iraq 29
PK - Pakistan 28
AU - Australia 24
MX - Messico 24
AR - Argentina 23
BE - Belgio 23
NL - Olanda 23
SA - Arabia Saudita 21
ZA - Sudafrica 21
ID - Indonesia 19
VE - Venezuela 19
EG - Egitto 14
ES - Italia 14
SN - Senegal 14
CO - Colombia 12
JO - Giordania 12
UZ - Uzbekistan 12
IE - Irlanda 10
KE - Kenya 10
PE - Perù 10
PL - Polonia 10
AZ - Azerbaigian 9
EC - Ecuador 9
MY - Malesia 9
LB - Libano 7
PY - Paraguay 7
CL - Cile 6
CZ - Repubblica Ceca 6
JM - Giamaica 6
KZ - Kazakistan 6
MA - Marocco 6
AE - Emirati Arabi Uniti 5
DZ - Algeria 5
LT - Lituania 5
OM - Oman 5
TW - Taiwan 5
AL - Albania 4
DK - Danimarca 4
ET - Etiopia 4
HU - Ungheria 4
IR - Iran 4
PH - Filippine 4
PT - Portogallo 4
TT - Trinidad e Tobago 4
BJ - Benin 3
CR - Costa Rica 3
IL - Israele 3
KH - Cambogia 3
NP - Nepal 3
PA - Panama 3
QA - Qatar 3
UY - Uruguay 3
BO - Bolivia 2
CY - Cipro 2
DO - Repubblica Dominicana 2
GE - Georgia 2
GR - Grecia 2
GT - Guatemala 2
MK - Macedonia 2
NZ - Nuova Zelanda 2
PS - Palestinian Territory 2
RS - Serbia 2
SO - Somalia 2
AM - Armenia 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BN - Brunei Darussalam 1
CG - Congo 1
EE - Estonia 1
EU - Europa 1
GA - Gabon 1
GD - Grenada 1
GL - Groenlandia 1
HN - Honduras 1
Totale 17.810
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Città #
Woodbridge 920
Ann Arbor 847
Ashburn 792
Singapore 727
Houston 693
Hong Kong 573
Serra 564
Chandler 549
San Jose 487
Santa Clara 484
Milan 448
Fairfield 437
Sofia 273
Izmir 261
Beijing 257
Shanghai 224
Dallas 221
Jacksonville 195
New York 185
Seattle 181
Ottawa 175
Wilmington 173
Cambridge 147
Los Angeles 141
Boardman 129
London 129
Princeton 121
Nanjing 111
Lawrence 110
Lauterbourg 105
Dong Ket 103
Hefei 93
Ho Chi Minh City 93
Medford 79
Frankfurt am Main 75
Tokyo 72
Seoul 71
Vienna 66
Council Bluffs 63
Des Moines 61
Abidjan 57
Dearborn 56
Hanoi 55
Rome 55
Helsinki 54
Istanbul 53
Buffalo 48
Bern 43
Rho 38
Jüchen 32
Kunming 31
Chicago 30
Lagos 30
Redondo Beach 30
Shenyang 30
Nanchang 29
Boulder 28
Bremen 28
Düsseldorf 28
Pune 27
Fuzhou 25
Munich 25
Redwood City 25
San Francisco 25
São Paulo 24
The Dalles 24
Brussels 23
Ogden 22
Changsha 21
Columbus 21
Orem 20
San Diego 20
Nürnberg 19
Turku 19
Hebei 18
Pisa 18
Washington 16
Tianjin 15
Da Nang 14
Dakar 14
Florence 14
Toronto 14
Aversa 13
Paris 13
Sydney 13
Johannesburg 12
Norwalk 12
Rio de Janeiro 12
Baghdad 11
Belo Horizonte 11
Secaucus 11
Tashkent 11
Amman 10
Baltimore 10
Falls Church 10
Jiaxing 10
Orange 10
Porto Alegre 10
Chennai 9
Dhaka 9
Totale 12.850
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Nome #
1,2-Benzisothiazole Derivatives Bearing 4-, 5-, or 6-Alkyl/arylcarboxamide Moieties Inhibit Carbonic Anhydrase Isoform IX (CAIX) and Cell Proliferation under Hypoxic Conditions 414
N, N-Dialkyl-2-phenylindol-3-ylglyoxylamides.A new class of potent and selective ligands at the Peripheral benzodiazepine receptor 293
Benzofuroxane Derivatives as Multi Effective Agents for the Treatment of Cardiovascular Diabetic Complications. Synthesis, Functional Evaluation, and Molecular Modeling Studies 278
Exploiting the Pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors, 272
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 243
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: a New Class of Selective Aldose Reductase Inhibitors 236
TSPO-ligands prevent oxidative damage and inflammatory response in C6 glioma cells by neurosteroid synthesis 232
Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII 231
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: A New Class of Selective Aldose Reductase Inhibitors 223
Investigation of new 2-aryl substituted Benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors targeting vascular endothelial growth factor receptor 2 212
Identification of Anxiolytic/Nonsedative Agents among Indol-3-ylglyoxylamides Acting as Functionally Selective Agonists at the γ-Aminobutyric Acid-A (GABAA) α2 Benzodiazepine Receptor 210
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of non-camptothecin Topoisomerase I (Top1) inhibitors 208
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: A Novel Template for the Design of Highly Selective A(2B) Adenosine Receptor Antagonists. 207
Structure-Based Optimization of Tyrosine Kinase Inhibitor CLM3. Design, Synthesis, Functional Evaluation, and Molecular Modeling Studies. 205
Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases 205
Geometrically Constrained Analogues N-Benzylindolylglyoxylylamides: [1,2,4]Triazino[4,3-a]benzimidazol-4(10H)-one Derivatives as Potential New Ligands at the Benzodiazepine Receptor. 202
Medicinal chemistry of indolylglyoxylamide TSPO high affinity ligands with anxiolytic-like effects 201
Discovery of Pyrido[3′,2′:5,6]thiopyrano[4,3- d]pyrimidine-Based Antiproliferative Multikinase Inhibitors 200
New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors 198
Studies in search for selective ligands for GABAA/BzR receptor subtypes: synthesis and biological evaluation of 4'-modified N-(benzyl)indol-3-ylglyoxylamides 197
Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity 197
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A(2B) adenosine receptor antagonists 195
5-Amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a Versatile Scaffold to Obtain Potent and Selective A3 Adenosine Receptor Antagonists 194
Benzothiopyranoindole-Based Antiproliferative Agents: Synthesis, Cytotoxicity, Nucleic Acids Interaction, and Topoisomerases Inhibition Properties. 194
Medicinal chemistry of indolylglyoxylamide GABAA/BzR high affinity ligands: identification of novel anxiolytic/non sedative agents 194
Refinement of Structure-activity Relationships of the Triazinobenzimidazole A1AR Antagonists 193
Translocator protein (tspo) ligand residence time: a new parameter to predict neurosteroidogenic efficacy for n,n-dialkyl-2-arylindol-3-ylglyoxylamides (PIGAs) 193
Synthesis of a Novel Purine-Containing Heterocyclic Ring System: 8,10-Dimethylindolo[2',3':5,6][1,2,4]triazino[4,3-f]purine-9,11(8H,10H,13H)dione 191
Benzo[d]isothiazoles and Matrix Metalloproteinases. Searching for Novel and Selective Inhibitors of MMP9 190
“Synthesis and antiproliferative evaluation of new substituted Benzothiopyrano[4,3-c] condensed ring systems” 188
Recent Advances in the Development of Dual Topoisomerase I and II Inhibitors as Anticancer Drugs 185
Novel N(2)-Substituted Pyrazolo[3,4-d]pyrimidine Adenosine A(3) Receptor Antagonists: Inhibition of A(3)-Mediated Human Glioblastoma Cell Proliferation (dagger) 184
Novel Pyrazolo[3,4-d]pyrimidine Derivatives as ATP-competitive Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase 183
New antiproliferative agents derived from tricyclic 3,4-dihydrobenzo[4,5]imidazo[1,2-a][1,3,5]triazine scaffold: synthesis and pharmacological effects 181
Novel, Highly Potent Aldose Reductase Inhibitors:Cyano(2-oxo-2,3-dihydroindol-3-yl)acetic Acid Derivatives 181
Novel Potent and Selective Human Adenosine A3 Receptor Antagonists Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis and Biological Evaluation 179
FACILE SYNTHESIS OF 3-SUBSTITUTED[1,2,4]TRIAZINO[3,4-F]PURINE-4,6,8-TRIONE DERIVATIVES 179
Synthesis of novel pyrido[3',2':5,6]thiopyrano[3,2-b]indol-5(6H)-ones and 6H-pyrido[3',2':5,6]thiopyrano[4,3-b]quinolines,two new heterocyclic systems. 178
An approach to novel fused triazole or tetrazole derivatives starting from Benzimidazo[1,2-a]quinazoline-5(7H)-one and 5,7-Dihydro-5-oxopyrido[3',2':5,6]pyrimido[1,2-a]benzimidazole 177
Antitumoral effect by induction of collapse of mitochondrial membrane potential in Glioblastoma Multiforme cells 176
Nuovi derivati acidi acetici quali potenti inibitori dell’Aldoso Reduttasi 171
Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: Stimulation of in vitro neurosteroid production affecting GABA(A) receptor activity 170
New fluorescent probes for the pheripheral-type benzodiazepine receptor: synthesis and biological application 169
Geometrically Constrained Derivatives of Indolylglyoxylamides as Ligands Binding the GABAA/BzR Complex. 169
Synthesis and Biological Evaluation of Pyrido[1,2-d]pyrimidin-4-one Derivatives as Novel Aldose Reductase Inhibitors Exhibiting Antioxidant Activity 167
PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a new mitochondrial benzodiazepine-receptor ligand, induces apoptosis in C6 glioma cells 166
Acetic acid aldose reductase inhibitors bearing a five-membered heterocyclic core with potent topical activity in a visual impairment rat model 166
Small Molecules Containing the Benzo[d]isotiazole Ring System as Novel ATP-Competitive Inhibitors of Epidermal Growth Factor Receptor protein Tyrosine Kinase 165
Pyrazolo[3,4,-d]pyrimidine-4-one Derivatives as Novel and Potent Inhibitors of Adenosine Deaminase 165
Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands 165
Tertiary amides with a five-membered heteroaromatic ring as new probes for the translocator protein 162
Naphtho[1,2-d]isothiazole Acetic Acid Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors 161
Refinement of the translocator protein pharmacophore/receptor model via structure-activity relationships of novel N,N-dialkylindolylglyoxylamides 159
Synthesis of New Heterocyclic Ring Systems via [1,3,5]Triazino[1,2-a]benzimidazole Derivatives 159
N,N-Dialkyl-2-phenylindol-3- ylglyoxylamides. A New Class of Potent and Selective Ligands at the Peripheral Benzodiazepine Receptor 159
2-(phenylsulphonamido)-pyrazole derivatives as carbonic anhydrase inhibitors 158
Microwave-assisted Suzuki Coupling in Aqueous Media: a Useful Tool for the Synthesis of 3-Arylindazole Derivatives 156
Novel Aldose Reductase Acetic acid Inhibitors Bearing a Five Membered heterocyclic core 156
Novel Antitumoral Pyrazolopyrimidines Based on Inhibition of Protein Tyrosine Kinase 154
Synthesis and Benzodiazepine Receptor Affinity of Derivatives of the New Tricyclic Heteroaromatic System Pyrido[3’,2’:5,6]thiopyrano[4,3-c]pyridazin-3(2H,5H)-one 154
Synthesis of pyrrolo[3,4-c]pyridine derivatives possessing an acid group and their in vitro and in vivo evaluation as aldose reductase inhibitors 151
A 2-phenylindol-3-ylglyoxylammide derivative, a new-synthesized peripheral benzodiazepine receptor ligand, induces apoptosis in rat C6 glioma cells 151
Benzisothiazole-1,1-dioxide alkanoic acid derivatives as inhibitors of rat lens aldose reductase 150
Refinement of the Benzodiazepine Receptor Site Topology by Structure-Activity Relationships of New N-(Heteroarylmethyl)indol-3-ylglyoxylamides 150
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of noncamptothecin Topoisomerase I (top1) inhibitors 149
1-(PHENYLSULPHONAMIDO)-PYRAZOLE DERIVATIVES AS CARBONIC ANHYDRASE INHIBITORS. 146
3-Aryl-1,2,4-triazino-4,3-abenzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists 144
Cell survival/death processes: Role of the mitochondrial Tranlocator Protein (TSPO) ligands 143
EFFECTS OF TSPO-LIGANDS ON MITOCHONDRIAL VOLUME AND MITOCHONDRIAL MEMBRANE POTENTIAL 142
New oxazole and 1,2,4-oxadiazole derivatives as selective ligands at the Translocator Protein (TSPO) 142
Anxiolytic-like Effects of N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides by Modulation of Translocator Protein Promoting Neurosteroid Biosynthesis 142
New Fluorescent 2-Phenylindoleglyoxylamide Derivatives as Probes Targeting the Peripheral-Type Benzodiazepine Receptor: Design, Synthesis, and Biological Evaluation 141
Novel Irreversible Fluorescent Probes Targeting the 18 kDa Translocator Protein: Synthesis and Biological Characterization 141
Design, Synthesis, and Biological Evaluation of 3-Arylindazole Acetic Acid Derivatives as Aldose Reductase Inhibitors 139
Acid derivatives of benzisothiazole-1,1-dioxide as inhibitors of rat lens aldose reductase 139
Synthesis and biological evaluation of Modified 2-Phenylindol-3-ylglyoxylamides as good candidates for the development of radioligands for the visualization of peripheral benzodiazepine receptor 139
Exploiting the pyrazolo[3,4-d]pyrimidinone ring system as a useful template for the obtainment of potent adenosine deaminase inhibitors 138
Benzoxadiazole Derivatives: Atypical Inhibitors of Aldose Reductase 135
Design, synthesis, and biological evaluation of novel fluorescent probes targeting the Translocator Protein (18 kDa) (TSPO) 134
2-Phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one derivatives as a new class of adenosine receptor antagonists 133
Novel Highly Potent Adenosine Deaminase Inhibitors Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis, Structure-Activity Relationships and Molecular Modeling Studies 131
Pyridopyrimidinone Derivatives as Novel Therapeutic Agents for the Topic Treatment of Vessel Walls Subjected to Percutaneous Intervention 130
Synthesis and local anaesthetic activity of some 7-amino-2-dialkylaminoalkylpyrrolo[3,4-c]pyridine derivatives 130
Tricyclic Sulfonamides Incorporating Benzothiopyrano[4,3-c]pyrazole and Pyridothiopyrano[4,3-c]pyrazole Effectively Inhibit a- and ß-Carbonic Anhydrase: X-ray Crystallography and Solution Investigations on 15 Isoforms 130
N,N-dialkyl-2-phenylindol-3-ylglyoxylylamide derivatives: a new class of potent and selective "pheripheral-type" benzodiazepine receptor ligands 129
Novel Pyrazolopyrimidine Derivatives as Therapeutic Agents for the Treatment of Medullary Thyroid Carcinoma 129
Targeting the Translocator protein (TSPO) with 2-phenylindol-3-ylglyoxylamide derivatives 128
Translocator Protein 18-kDa: a promising target to treat neuroinflammation-related degenerative diseases 128
NOVEL KINASE INHIBITORS IN THYROID CANCER TREATMENT: SYNTHESIS AND BIOLOGICAL EVALUATION 126
Development of novel indole-based tdp1 inhibitors for anticancer therapy 125
Synthesis and biological evaluation on human glioblastoma cells of novel pyrazolo[3,4-d]pyrimidine adenosine A(3) receptor antagonists. 123
Novel, Highly Potent Adenosine Deaminase Inhibitors Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synhesis, Structure-Activity Relationships, and Molecular Modeling Studies 122
2-PHENYL[1,2,3]TRIAZOLO[1,2-a]BENZOTRIAZIN-1-ONE DERIVATIVES AS A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS 121
Synthesis and Antiproliferative Activity of New Aminoalkyl Substituted Benzothiopyranoindoles 121
Substituted 2-Arylindolglyoxylamides as Potent Translocator Protein (18 kDa) TSPO ligands: Synthesis and Biological Evaluation 121
Glioblastoma multiforme: antitumoral in vitro effect by induction of collapse of mitochondrial membrane potential 119
Progettazione e sintesi di nuovi derivati 2-fenilindol-3-ilgliossilamidici per un approfondimento delle relazioni struttura attività (SAR) di questa classe di ligandi potenti e selettivi per il PBR 117
"Sintesi e attività antiproliferativa di sistemi Pirido[3’,2’:5,6]tiopirano[4,3-c]pirazolici 2-aril sostituiti" 115
Synthesis and benzodiazepine receptor activity of some 4,5-dihydro-1H-pyrazolo[4,3-c][1,8]naphthyridine derivatives. 111
"Synthesis of new indolo[3,2-c][1,8]naphthyridine derivatives as antiproliferative agents" 110
Totale 16.965
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Categoria #
all - tutte 47.335
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 47.335
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021196 0 0 0 0 0 0 0 0 0 0 0 196
2021/20221.236 24 93 57 88 226 143 18 58 49 24 83 373
2022/20231.847 237 350 121 170 218 219 22 145 278 7 63 17
2023/20241.408 200 184 159 122 222 238 41 28 21 38 37 118
2024/20253.415 28 131 25 211 429 344 196 157 311 447 357 779
2025/20263.442 181 354 320 210 376 333 739 175 250 343 136 25
Totale 18.028