CINECA IRIS Institutional Research Information System

SIMORINI, FRANCESCA
 Distribuzione geografica
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Continente #
NA - Nord America 6.720
EU - Europa 3.722
AS - Asia 1.887
AF - Africa 113
SA - Sud America 92
OC - Oceania 26
Continente sconosciuto - Info sul continente non disponibili 1
Totale 12.561
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Nazione #
US - Stati Uniti d'America 6.533
IT - Italia 1.497
CN - Cina 842
SE - Svezia 766
DE - Germania 393
SG - Singapore 334
TR - Turchia 314
BG - Bulgaria 273
GB - Regno Unito 205
CA - Canada 182
VN - Vietnam 172
UA - Ucraina 131
RU - Federazione Russa 127
FI - Finlandia 111
HK - Hong Kong 106
BR - Brasile 80
AT - Austria 77
IN - India 68
CI - Costa d'Avorio 56
CH - Svizzera 44
NG - Nigeria 31
AU - Australia 24
FR - Francia 24
BE - Belgio 23
NL - Olanda 17
JP - Giappone 15
SN - Senegal 12
EG - Egitto 10
PK - Pakistan 7
CZ - Repubblica Ceca 6
IE - Irlanda 6
DK - Danimarca 4
IR - Iran 4
JO - Giordania 4
LT - Lituania 4
AZ - Azerbaigian 3
BJ - Benin 3
EC - Ecuador 3
ID - Indonesia 3
PL - Polonia 3
VE - Venezuela 3
AL - Albania 2
AR - Argentina 2
BD - Bangladesh 2
GR - Grecia 2
HU - Ungheria 2
KZ - Kazakistan 2
MX - Messico 2
NZ - Nuova Zelanda 2
PE - Perù 2
PT - Portogallo 2
AE - Emirati Arabi Uniti 1
BA - Bosnia-Erzegovina 1
CL - Cile 1
CO - Colombia 1
EU - Europa 1
GA - Gabon 1
GE - Georgia 1
GL - Groenlandia 1
HN - Honduras 1
HR - Croazia 1
IQ - Iraq 1
JM - Giamaica 1
KR - Corea 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
MC - Monaco 1
MY - Malesia 1
PS - Palestinian Territory 1
SA - Arabia Saudita 1
TH - Thailandia 1
UZ - Uzbekistan 1
Totale 12.561
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Città #
Woodbridge 920
Ann Arbor 847
Houston 687
Serra 564
Chandler 549
Santa Clara 464
Milan 444
Fairfield 437
Ashburn 338
Sofia 273
Izmir 259
Shanghai 225
Beijing 202
Jacksonville 193
Seattle 178
Ottawa 173
Wilmington 170
New York 156
Cambridge 147
Singapore 144
Boardman 125
London 123
Princeton 121
Nanjing 111
Lawrence 110
Hong Kong 105
Dong Ket 103
Medford 79
Vienna 64
Des Moines 61
Abidjan 56
Dearborn 56
Rome 54
Frankfurt am Main 53
Istanbul 49
Bern 43
Los Angeles 39
Rho 38
Jüchen 32
Lagos 30
Kunming 29
Nanchang 29
Boulder 28
Bremen 28
Shenyang 27
Pune 26
Fuzhou 25
Redwood City 25
Düsseldorf 24
Brussels 23
Ogden 22
Chicago 21
San Diego 20
Changsha 19
Nürnberg 19
Hebei 18
Pisa 16
Tianjin 15
Aversa 13
Florence 13
Sydney 13
Washington 13
Council Bluffs 12
Dakar 12
Norwalk 12
Hefei 11
Falls Church 10
Jiaxing 10
Orange 10
Dallas 9
Helsinki 9
Quanzhou 9
Auburn Hills 8
Hangzhou 8
Lancaster 8
Melbourne 8
San Francisco 8
Guangzhou 7
Toronto 7
Amsterdam 6
Brno 6
Jinan 6
Tappahannock 6
Caserta 5
Cecina 5
Dublin 5
Massa 5
Omaha 5
Vicopisano 5
Amman 4
Ankara 4
Augusta 4
Cascina 4
Indiana 4
Mumbai 4
Paris 4
Phoenix 4
São Paulo 4
Wuhan 4
Belo Horizonte 3
Totale 9.543
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Nome #
1,2-Benzisothiazole Derivatives Bearing 4-, 5-, or 6-Alkyl/arylcarboxamide Moieties Inhibit Carbonic Anhydrase Isoform IX (CAIX) and Cell Proliferation under Hypoxic Conditions 338
Benzofuroxane Derivatives as Multi Effective Agents for the Treatment of Cardiovascular Diabetic Complications. Synthesis, Functional Evaluation, and Molecular Modeling Studies 217
N, N-Dialkyl-2-phenylindol-3-ylglyoxylamides.A new class of potent and selective ligands at the Peripheral benzodiazepine receptor 214
Exploiting the Pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors, 196
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: a New Class of Selective Aldose Reductase Inhibitors 187
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: A New Class of Selective Aldose Reductase Inhibitors 181
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 179
Identification of Anxiolytic/Nonsedative Agents among Indol-3-ylglyoxylamides Acting as Functionally Selective Agonists at the γ-Aminobutyric Acid-A (GABAA) α2 Benzodiazepine Receptor 171
TSPO-ligands prevent oxidative damage and inflammatory response in C6 glioma cells by neurosteroid synthesis 163
Synthesis of a Novel Purine-Containing Heterocyclic Ring System: 8,10-Dimethylindolo[2',3':5,6][1,2,4]triazino[4,3-f]purine-9,11(8H,10H,13H)dione 158
Geometrically Constrained Analogues N-Benzylindolylglyoxylylamides: [1,2,4]Triazino[4,3-a]benzimidazol-4(10H)-one Derivatives as Potential New Ligands at the Benzodiazepine Receptor. 156
Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity 156
Refinement of Structure-activity Relationships of the Triazinobenzimidazole A1AR Antagonists 155
Medicinal chemistry of indolylglyoxylamide TSPO high affinity ligands with anxiolytic-like effects 152
5-Amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a Versatile Scaffold to Obtain Potent and Selective A3 Adenosine Receptor Antagonists 152
Benzo[d]isothiazoles and Matrix Metalloproteinases. Searching for Novel and Selective Inhibitors of MMP9 149
“Synthesis and antiproliferative evaluation of new substituted Benzothiopyrano[4,3-c] condensed ring systems” 148
Recent Advances in the Development of Dual Topoisomerase I and II Inhibitors as Anticancer Drugs 148
Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII 148
FACILE SYNTHESIS OF 3-SUBSTITUTED[1,2,4]TRIAZINO[3,4-F]PURINE-4,6,8-TRIONE DERIVATIVES 147
Benzothiopyranoindole-Based Antiproliferative Agents: Synthesis, Cytotoxicity, Nucleic Acids Interaction, and Topoisomerases Inhibition Properties. 147
Novel, Highly Potent Aldose Reductase Inhibitors:Cyano(2-oxo-2,3-dihydroindol-3-yl)acetic Acid Derivatives 144
Novel N(2)-Substituted Pyrazolo[3,4-d]pyrimidine Adenosine A(3) Receptor Antagonists: Inhibition of A(3)-Mediated Human Glioblastoma Cell Proliferation (dagger) 143
An approach to novel fused triazole or tetrazole derivatives starting from Benzimidazo[1,2-a]quinazoline-5(7H)-one and 5,7-Dihydro-5-oxopyrido[3',2':5,6]pyrimido[1,2-a]benzimidazole 138
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of non-camptothecin Topoisomerase I (Top1) inhibitors 138
Structure-Based Optimization of Tyrosine Kinase Inhibitor CLM3. Design, Synthesis, Functional Evaluation, and Molecular Modeling Studies. 138
Medicinal chemistry of indolylglyoxylamide GABAA/BzR high affinity ligands: identification of novel anxiolytic/non sedative agents 137
Studies in search for selective ligands for GABAA/BzR receptor subtypes: synthesis and biological evaluation of 4'-modified N-(benzyl)indol-3-ylglyoxylamides 136
Novel Potent and Selective Human Adenosine A3 Receptor Antagonists Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis and Biological Evaluation 136
Synthesis of novel pyrido[3',2':5,6]thiopyrano[3,2-b]indol-5(6H)-ones and 6H-pyrido[3',2':5,6]thiopyrano[4,3-b]quinolines,two new heterocyclic systems. 132
Acetic acid aldose reductase inhibitors bearing a five-membered heterocyclic core with potent topical activity in a visual impairment rat model 132
Investigation of new 2-aryl substituted Benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors targeting vascular endothelial growth factor receptor 2 131
Novel Pyrazolo[3,4-d]pyrimidine Derivatives as ATP-competitive Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase 129
Synthesis of New Heterocyclic Ring Systems via [1,3,5]Triazino[1,2-a]benzimidazole Derivatives 129
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A(2B) adenosine receptor antagonists 129
Translocator protein (tspo) ligand residence time: a new parameter to predict neurosteroidogenic efficacy for n,n-dialkyl-2-arylindol-3-ylglyoxylamides (PIGAs) 129
Tertiary amides with a five-membered heteroaromatic ring as new probes for the translocator protein 127
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: A Novel Template for the Design of Highly Selective A(2B) Adenosine Receptor Antagonists. 127
Naphtho[1,2-d]isothiazole Acetic Acid Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors 125
Small Molecules Containing the Benzo[d]isotiazole Ring System as Novel ATP-Competitive Inhibitors of Epidermal Growth Factor Receptor protein Tyrosine Kinase 123
Pyrazolo[3,4,-d]pyrimidine-4-one Derivatives as Novel and Potent Inhibitors of Adenosine Deaminase 123
Antitumoral effect by induction of collapse of mitochondrial membrane potential in Glioblastoma Multiforme cells 123
Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: Stimulation of in vitro neurosteroid production affecting GABA(A) receptor activity 123
Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands 123
Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases 122
Microwave-assisted Suzuki Coupling in Aqueous Media: a Useful Tool for the Synthesis of 3-Arylindazole Derivatives 120
PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a new mitochondrial benzodiazepine-receptor ligand, induces apoptosis in C6 glioma cells 120
Synthesis and Biological Evaluation of Pyrido[1,2-d]pyrimidin-4-one Derivatives as Novel Aldose Reductase Inhibitors Exhibiting Antioxidant Activity 118
Novel Aldose Reductase Acetic acid Inhibitors Bearing a Five Membered heterocyclic core 117
Novel Irreversible Fluorescent Probes Targeting the 18 kDa Translocator Protein: Synthesis and Biological Characterization 117
Geometrically Constrained Derivatives of Indolylglyoxylamides as Ligands Binding the GABAA/BzR Complex. 117
New fluorescent probes for the pheripheral-type benzodiazepine receptor: synthesis and biological application 114
Cell survival/death processes: Role of the mitochondrial Tranlocator Protein (TSPO) ligands 114
Refinement of the Benzodiazepine Receptor Site Topology by Structure-Activity Relationships of New N-(Heteroarylmethyl)indol-3-ylglyoxylamides 114
N,N-Dialkyl-2-phenylindol-3- ylglyoxylamides. A New Class of Potent and Selective Ligands at the Peripheral Benzodiazepine Receptor 114
1-(PHENYLSULPHONAMIDO)-PYRAZOLE DERIVATIVES AS CARBONIC ANHYDRASE INHIBITORS. 112
Benzisothiazole-1,1-dioxide alkanoic acid derivatives as inhibitors of rat lens aldose reductase 111
Synthesis and Benzodiazepine Receptor Affinity of Derivatives of the New Tricyclic Heteroaromatic System Pyrido[3’,2’:5,6]thiopyrano[4,3-c]pyridazin-3(2H,5H)-one 111
Novel Antitumoral Pyrazolopyrimidines Based on Inhibition of Protein Tyrosine Kinase 110
A 2-phenylindol-3-ylglyoxylammide derivative, a new-synthesized peripheral benzodiazepine receptor ligand, induces apoptosis in rat C6 glioma cells 108
Discovery of Pyrido[3′,2′:5,6]thiopyrano[4,3- d]pyrimidine-Based Antiproliferative Multikinase Inhibitors 108
Acid derivatives of benzisothiazole-1,1-dioxide as inhibitors of rat lens aldose reductase 106
Synthesis of pyrrolo[3,4-c]pyridine derivatives possessing an acid group and their in vitro and in vivo evaluation as aldose reductase inhibitors 105
Synthesis and biological evaluation of Modified 2-Phenylindol-3-ylglyoxylamides as good candidates for the development of radioligands for the visualization of peripheral benzodiazepine receptor 105
EFFECTS OF TSPO-LIGANDS ON MITOCHONDRIAL VOLUME AND MITOCHONDRIAL MEMBRANE POTENTIAL 104
Exploiting the pyrazolo[3,4-d]pyrimidinone ring system as a useful template for the obtainment of potent adenosine deaminase inhibitors 104
New Fluorescent 2-Phenylindoleglyoxylamide Derivatives as Probes Targeting the Peripheral-Type Benzodiazepine Receptor: Design, Synthesis, and Biological Evaluation 104
Nuovi derivati acidi acetici quali potenti inibitori dell’Aldoso Reduttasi 103
2-Phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one derivatives as a new class of adenosine receptor antagonists 103
New oxazole and 1,2,4-oxadiazole derivatives as selective ligands at the Translocator Protein (TSPO) 102
Design, Synthesis, and Biological Evaluation of 3-Arylindazole Acetic Acid Derivatives as Aldose Reductase Inhibitors 100
Pyridopyrimidinone Derivatives as Novel Therapeutic Agents for the Topic Treatment of Vessel Walls Subjected to Percutaneous Intervention 100
Anxiolytic-like Effects of N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides by Modulation of Translocator Protein Promoting Neurosteroid Biosynthesis 99
Synthesis and local anaesthetic activity of some 7-amino-2-dialkylaminoalkylpyrrolo[3,4-c]pyridine derivatives 98
Design, synthesis, and biological evaluation of novel fluorescent probes targeting the Translocator Protein (18 kDa) (TSPO) 97
2-(phenylsulphonamido)-pyrazole derivatives as carbonic anhydrase inhibitors 94
Novel Pyrazolopyrimidine Derivatives as Therapeutic Agents for the Treatment of Medullary Thyroid Carcinoma 92
Tricyclic Sulfonamides Incorporating Benzothiopyrano[4,3-c]pyrazole and Pyridothiopyrano[4,3-c]pyrazole Effectively Inhibit a- and ß-Carbonic Anhydrase: X-ray Crystallography and Solution Investigations on 15 Isoforms 91
New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors 91
NOVEL KINASE INHIBITORS IN THYROID CANCER TREATMENT: SYNTHESIS AND BIOLOGICAL EVALUATION 90
Glioblastoma multiforme: antitumoral in vitro effect by induction of collapse of mitochondrial membrane potential 89
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of noncamptothecin Topoisomerase I (top1) inhibitors 89
Novel Highly Potent Adenosine Deaminase Inhibitors Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis, Structure-Activity Relationships and Molecular Modeling Studies 85
N,N-dialkyl-2-phenylindol-3-ylglyoxylylamide derivatives: a new class of potent and selective "pheripheral-type" benzodiazepine receptor ligands 84
Synthesis and Antiproliferative Activity of New Aminoalkyl Substituted Benzothiopyranoindoles 84
Targeting the Translocator protein (TSPO) with 2-phenylindol-3-ylglyoxylamide derivatives 84
Novel, Highly Potent Adenosine Deaminase Inhibitors Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synhesis, Structure-Activity Relationships, and Molecular Modeling Studies 84
Benzoxadiazole Derivatives: Atypical Inhibitors of Aldose Reductase 83
"Sintesi e attività antiproliferativa di sistemi Pirido[3’,2’:5,6]tiopirano[4,3-c]pirazolici 2-aril sostituiti" 82
Dialkylaminoalkylindolonaphthyridines as potential antitumor agents: synthesis, cytotoxicity and DNA binding properties 82
Synthesis and biological evaluation on human glioblastoma cells of novel pyrazolo[3,4-d]pyrimidine adenosine A(3) receptor antagonists. 82
Substituted 2-Arylindolglyoxylamides as Potent Translocator Protein (18 kDa) TSPO ligands: Synthesis and Biological Evaluation 82
Synthesis and in vitro Antiproliferative Activity of New Substituted Benzo[3',2':5,6]thiopyrano[4,3-d]pyrimidines 81
Refinement of the translocator protein pharmacophore/receptor model via structure-activity relationships of novel N,N-dialkylindolylglyoxylamides 79
Progettazione e sintesi di nuovi derivati 2-fenilindol-3-ilgliossilamidici per un approfondimento delle relazioni struttura attività (SAR) di questa classe di ligandi potenti e selettivi per il PBR 77
"Synthesis of new indolo[3,2-c][1,8]naphthyridine derivatives as antiproliferative agents" 77
3-Aryl-1,2,4-triazino-4,3-abenzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists 77
Synthesis and benzodiazepine receptor activity of some 4,5-dihydro-1H-pyrazolo[4,3-c][1,8]naphthyridine derivatives. 72
"Facile sintesi di nuove molecole polieterocicliche a partire dal 2-guanidinobenzimidazolo" 71
2-PHENYL[1,2,3]TRIAZOLO[1,2-a]BENZOTRIAZIN-1-ONE DERIVATIVES AS A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS 70
Totale 12.126
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Categoria #
all - tutte 32.792
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 32.792
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020394 0 0 0 0 0 0 0 0 130 90 159 15
2020/2021917 175 33 54 44 89 34 41 71 73 52 55 196
2021/20221.236 24 93 57 88 226 143 18 58 49 24 83 373
2022/20231.847 237 350 121 170 218 219 22 145 278 7 63 17
2023/20241.408 200 184 159 122 222 238 41 28 21 38 37 118
2024/20251.584 28 131 25 211 429 346 201 158 55 0 0 0
Totale 12.755