CINECA IRIS Institutional Research Information System

SIMORINI, FRANCESCA
 Distribuzione geografica
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Continente #
NA - Nord America 7.853
EU - Europa 3.929
AS - Asia 3.733
SA - Sud America 448
AF - Africa 165
OC - Oceania 26
Continente sconosciuto - Info sul continente non disponibili 1
Totale 16.155
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Nazione #
US - Stati Uniti d'America 7.613
IT - Italia 1.517
CN - Cina 1.128
SG - Singapore 1.106
SE - Svezia 776
HK - Hong Kong 564
DE - Germania 435
BR - Brasile 374
TR - Turchia 330
BG - Bulgaria 274
GB - Regno Unito 246
CA - Canada 200
VN - Vietnam 196
UA - Ucraina 138
RU - Federazione Russa 133
FI - Finlandia 130
IN - India 112
AT - Austria 80
KR - Corea 72
CI - Costa d'Avorio 57
JP - Giappone 50
CH - Svizzera 45
FR - Francia 45
NG - Nigeria 32
BD - Bangladesh 26
AU - Australia 24
BE - Belgio 23
MX - Messico 21
NL - Olanda 21
AR - Argentina 20
PK - Pakistan 19
IQ - Iraq 17
SA - Arabia Saudita 17
ZA - Sudafrica 17
VE - Venezuela 14
EG - Egitto 13
ID - Indonesia 13
SN - Senegal 13
CO - Colombia 10
ES - Italia 10
PL - Polonia 10
UZ - Uzbekistan 10
IE - Irlanda 9
KE - Kenya 9
MY - Malesia 9
AZ - Azerbaigian 8
JO - Giordania 8
EC - Ecuador 7
PE - Perù 7
PY - Paraguay 7
CZ - Repubblica Ceca 6
CL - Cile 5
KZ - Kazakistan 5
LB - Libano 5
LT - Lituania 5
OM - Oman 5
TW - Taiwan 5
AE - Emirati Arabi Uniti 4
AL - Albania 4
DK - Danimarca 4
DZ - Algeria 4
ET - Etiopia 4
IR - Iran 4
JM - Giamaica 4
MA - Marocco 4
BJ - Benin 3
PT - Portogallo 3
QA - Qatar 3
TT - Trinidad e Tobago 3
CY - Cipro 2
DO - Repubblica Dominicana 2
GR - Grecia 2
HU - Ungheria 2
IL - Israele 2
KH - Cambogia 2
MK - Macedonia 2
NZ - Nuova Zelanda 2
PA - Panama 2
PH - Filippine 2
PS - Palestinian Territory 2
SO - Somalia 2
UY - Uruguay 2
AO - Angola 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BN - Brunei Darussalam 1
BO - Bolivia 1
CR - Costa Rica 1
EE - Estonia 1
EU - Europa 1
GA - Gabon 1
GD - Grenada 1
GE - Georgia 1
GL - Groenlandia 1
HN - Honduras 1
HR - Croazia 1
KW - Kuwait 1
LC - Santa Lucia 1
LR - Liberia 1
LU - Lussemburgo 1
Totale 16.139
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Città #
Woodbridge 920
Ann Arbor 847
Ashburn 741
Houston 692
Singapore 611
Serra 564
Hong Kong 562
Chandler 549
Santa Clara 478
Milan 448
Fairfield 437
Sofia 273
Izmir 261
Beijing 252
Shanghai 224
Dallas 210
Jacksonville 195
New York 179
Seattle 179
Ottawa 175
Wilmington 173
Cambridge 147
Los Angeles 135
London 129
Boardman 127
Princeton 121
Nanjing 111
Lawrence 110
Dong Ket 103
Hefei 93
Medford 79
Seoul 71
Vienna 66
Frankfurt am Main 64
Des Moines 61
Abidjan 57
Dearborn 56
Rome 54
Istanbul 53
Buffalo 48
Bern 43
Rho 38
Council Bluffs 34
Jüchen 32
Kunming 31
Lagos 30
Redondo Beach 30
Shenyang 30
Tokyo 30
Nanchang 29
Boulder 28
Bremen 28
Düsseldorf 28
Chicago 26
Pune 26
Fuzhou 25
Munich 25
Redwood City 25
The Dalles 24
Brussels 23
Ogden 22
São Paulo 22
Changsha 21
Columbus 21
San Francisco 21
San Diego 20
Nürnberg 19
Turku 19
Hebei 18
Pisa 17
Tianjin 15
Washington 15
Aversa 13
Dakar 13
Florence 13
San Jose 13
Sydney 13
Norwalk 12
Paris 12
Belo Horizonte 11
Rio de Janeiro 11
Secaucus 11
Toronto 11
Falls Church 10
Ho Chi Minh City 10
Jiaxing 10
Orange 10
Porto Alegre 10
Guangzhou 9
Helsinki 9
Johannesburg 9
Quanzhou 9
Stockholm 9
Tashkent 9
Amman 8
Auburn Hills 8
Dhaka 8
Dublin 8
Hangzhou 8
Lancaster 8
Totale 11.755
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Nome #
1,2-Benzisothiazole Derivatives Bearing 4-, 5-, or 6-Alkyl/arylcarboxamide Moieties Inhibit Carbonic Anhydrase Isoform IX (CAIX) and Cell Proliferation under Hypoxic Conditions 383
N, N-Dialkyl-2-phenylindol-3-ylglyoxylamides.A new class of potent and selective ligands at the Peripheral benzodiazepine receptor 271
Benzofuroxane Derivatives as Multi Effective Agents for the Treatment of Cardiovascular Diabetic Complications. Synthesis, Functional Evaluation, and Molecular Modeling Studies 266
Exploiting the Pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors, 257
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: a New Class of Selective Aldose Reductase Inhibitors 223
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 219
TSPO-ligands prevent oxidative damage and inflammatory response in C6 glioma cells by neurosteroid synthesis 211
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: A New Class of Selective Aldose Reductase Inhibitors 209
Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII 198
Identification of Anxiolytic/Nonsedative Agents among Indol-3-ylglyoxylamides Acting as Functionally Selective Agonists at the γ-Aminobutyric Acid-A (GABAA) α2 Benzodiazepine Receptor 196
Geometrically Constrained Analogues N-Benzylindolylglyoxylylamides: [1,2,4]Triazino[4,3-a]benzimidazol-4(10H)-one Derivatives as Potential New Ligands at the Benzodiazepine Receptor. 193
Medicinal chemistry of indolylglyoxylamide TSPO high affinity ligands with anxiolytic-like effects 189
Structure-Based Optimization of Tyrosine Kinase Inhibitor CLM3. Design, Synthesis, Functional Evaluation, and Molecular Modeling Studies. 189
5-Amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a Versatile Scaffold to Obtain Potent and Selective A3 Adenosine Receptor Antagonists 186
Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity 183
Benzothiopyranoindole-Based Antiproliferative Agents: Synthesis, Cytotoxicity, Nucleic Acids Interaction, and Topoisomerases Inhibition Properties. 183
Investigation of new 2-aryl substituted Benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors targeting vascular endothelial growth factor receptor 2 183
Synthesis of a Novel Purine-Containing Heterocyclic Ring System: 8,10-Dimethylindolo[2',3':5,6][1,2,4]triazino[4,3-f]purine-9,11(8H,10H,13H)dione 182
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of non-camptothecin Topoisomerase I (Top1) inhibitors 182
Refinement of Structure-activity Relationships of the Triazinobenzimidazole A1AR Antagonists 181
Benzo[d]isothiazoles and Matrix Metalloproteinases. Searching for Novel and Selective Inhibitors of MMP9 181
Studies in search for selective ligands for GABAA/BzR receptor subtypes: synthesis and biological evaluation of 4'-modified N-(benzyl)indol-3-ylglyoxylamides 177
Medicinal chemistry of indolylglyoxylamide GABAA/BzR high affinity ligands: identification of novel anxiolytic/non sedative agents 175
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A(2B) adenosine receptor antagonists 174
“Synthesis and antiproliferative evaluation of new substituted Benzothiopyrano[4,3-c] condensed ring systems” 173
Novel Pyrazolo[3,4-d]pyrimidine Derivatives as ATP-competitive Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase 172
Novel N(2)-Substituted Pyrazolo[3,4-d]pyrimidine Adenosine A(3) Receptor Antagonists: Inhibition of A(3)-Mediated Human Glioblastoma Cell Proliferation (dagger) 172
Novel, Highly Potent Aldose Reductase Inhibitors:Cyano(2-oxo-2,3-dihydroindol-3-yl)acetic Acid Derivatives 172
Recent Advances in the Development of Dual Topoisomerase I and II Inhibitors as Anticancer Drugs 172
Novel Potent and Selective Human Adenosine A3 Receptor Antagonists Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis and Biological Evaluation 170
FACILE SYNTHESIS OF 3-SUBSTITUTED[1,2,4]TRIAZINO[3,4-F]PURINE-4,6,8-TRIONE DERIVATIVES 170
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: A Novel Template for the Design of Highly Selective A(2B) Adenosine Receptor Antagonists. 169
An approach to novel fused triazole or tetrazole derivatives starting from Benzimidazo[1,2-a]quinazoline-5(7H)-one and 5,7-Dihydro-5-oxopyrido[3',2':5,6]pyrimido[1,2-a]benzimidazole 168
Synthesis of novel pyrido[3',2':5,6]thiopyrano[3,2-b]indol-5(6H)-ones and 6H-pyrido[3',2':5,6]thiopyrano[4,3-b]quinolines,two new heterocyclic systems. 168
Discovery of Pyrido[3′,2′:5,6]thiopyrano[4,3- d]pyrimidine-Based Antiproliferative Multikinase Inhibitors 164
Translocator protein (tspo) ligand residence time: a new parameter to predict neurosteroidogenic efficacy for n,n-dialkyl-2-arylindol-3-ylglyoxylamides (PIGAs) 162
Antitumoral effect by induction of collapse of mitochondrial membrane potential in Glioblastoma Multiforme cells 160
Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: Stimulation of in vitro neurosteroid production affecting GABA(A) receptor activity 158
Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands 158
Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases 156
Tertiary amides with a five-membered heteroaromatic ring as new probes for the translocator protein 155
New fluorescent probes for the pheripheral-type benzodiazepine receptor: synthesis and biological application 154
Acetic acid aldose reductase inhibitors bearing a five-membered heterocyclic core with potent topical activity in a visual impairment rat model 154
PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a new mitochondrial benzodiazepine-receptor ligand, induces apoptosis in C6 glioma cells 153
Synthesis of New Heterocyclic Ring Systems via [1,3,5]Triazino[1,2-a]benzimidazole Derivatives 152
Nuovi derivati acidi acetici quali potenti inibitori dell’Aldoso Reduttasi 151
Synthesis and Biological Evaluation of Pyrido[1,2-d]pyrimidin-4-one Derivatives as Novel Aldose Reductase Inhibitors Exhibiting Antioxidant Activity 151
Pyrazolo[3,4,-d]pyrimidine-4-one Derivatives as Novel and Potent Inhibitors of Adenosine Deaminase 151
Small Molecules Containing the Benzo[d]isotiazole Ring System as Novel ATP-Competitive Inhibitors of Epidermal Growth Factor Receptor protein Tyrosine Kinase 150
Naphtho[1,2-d]isothiazole Acetic Acid Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors 150
N,N-Dialkyl-2-phenylindol-3- ylglyoxylamides. A New Class of Potent and Selective Ligands at the Peripheral Benzodiazepine Receptor 149
Microwave-assisted Suzuki Coupling in Aqueous Media: a Useful Tool for the Synthesis of 3-Arylindazole Derivatives 148
Geometrically Constrained Derivatives of Indolylglyoxylamides as Ligands Binding the GABAA/BzR Complex. 148
Novel Aldose Reductase Acetic acid Inhibitors Bearing a Five Membered heterocyclic core 147
Novel Antitumoral Pyrazolopyrimidines Based on Inhibition of Protein Tyrosine Kinase 143
New antiproliferative agents derived from tricyclic 3,4-dihydrobenzo[4,5]imidazo[1,2-a][1,3,5]triazine scaffold: synthesis and pharmacological effects 142
Synthesis and Benzodiazepine Receptor Affinity of Derivatives of the New Tricyclic Heteroaromatic System Pyrido[3’,2’:5,6]thiopyrano[4,3-c]pyridazin-3(2H,5H)-one 142
Benzisothiazole-1,1-dioxide alkanoic acid derivatives as inhibitors of rat lens aldose reductase 140
Refinement of the Benzodiazepine Receptor Site Topology by Structure-Activity Relationships of New N-(Heteroarylmethyl)indol-3-ylglyoxylamides 138
1-(PHENYLSULPHONAMIDO)-PYRAZOLE DERIVATIVES AS CARBONIC ANHYDRASE INHIBITORS. 137
Synthesis of pyrrolo[3,4-c]pyridine derivatives possessing an acid group and their in vitro and in vivo evaluation as aldose reductase inhibitors 137
A 2-phenylindol-3-ylglyoxylammide derivative, a new-synthesized peripheral benzodiazepine receptor ligand, induces apoptosis in rat C6 glioma cells 137
2-(phenylsulphonamido)-pyrazole derivatives as carbonic anhydrase inhibitors 136
Cell survival/death processes: Role of the mitochondrial Tranlocator Protein (TSPO) ligands 135
New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors 135
Novel Irreversible Fluorescent Probes Targeting the 18 kDa Translocator Protein: Synthesis and Biological Characterization 134
New Fluorescent 2-Phenylindoleglyoxylamide Derivatives as Probes Targeting the Peripheral-Type Benzodiazepine Receptor: Design, Synthesis, and Biological Evaluation 133
EFFECTS OF TSPO-LIGANDS ON MITOCHONDRIAL VOLUME AND MITOCHONDRIAL MEMBRANE POTENTIAL 132
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of noncamptothecin Topoisomerase I (top1) inhibitors 131
Acid derivatives of benzisothiazole-1,1-dioxide as inhibitors of rat lens aldose reductase 129
Synthesis and biological evaluation of Modified 2-Phenylindol-3-ylglyoxylamides as good candidates for the development of radioligands for the visualization of peripheral benzodiazepine receptor 129
Anxiolytic-like Effects of N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides by Modulation of Translocator Protein Promoting Neurosteroid Biosynthesis 129
Design, Synthesis, and Biological Evaluation of 3-Arylindazole Acetic Acid Derivatives as Aldose Reductase Inhibitors 127
Exploiting the pyrazolo[3,4-d]pyrimidinone ring system as a useful template for the obtainment of potent adenosine deaminase inhibitors 127
Synthesis and local anaesthetic activity of some 7-amino-2-dialkylaminoalkylpyrrolo[3,4-c]pyridine derivatives 126
New oxazole and 1,2,4-oxadiazole derivatives as selective ligands at the Translocator Protein (TSPO) 126
Refinement of the translocator protein pharmacophore/receptor model via structure-activity relationships of novel N,N-dialkylindolylglyoxylamides 125
Benzoxadiazole Derivatives: Atypical Inhibitors of Aldose Reductase 124
Pyridopyrimidinone Derivatives as Novel Therapeutic Agents for the Topic Treatment of Vessel Walls Subjected to Percutaneous Intervention 123
Novel Highly Potent Adenosine Deaminase Inhibitors Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis, Structure-Activity Relationships and Molecular Modeling Studies 123
2-Phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one derivatives as a new class of adenosine receptor antagonists 122
Design, synthesis, and biological evaluation of novel fluorescent probes targeting the Translocator Protein (18 kDa) (TSPO) 119
Novel Pyrazolopyrimidine Derivatives as Therapeutic Agents for the Treatment of Medullary Thyroid Carcinoma 118
Tricyclic Sulfonamides Incorporating Benzothiopyrano[4,3-c]pyrazole and Pyridothiopyrano[4,3-c]pyrazole Effectively Inhibit a- and ß-Carbonic Anhydrase: X-ray Crystallography and Solution Investigations on 15 Isoforms 118
N,N-dialkyl-2-phenylindol-3-ylglyoxylylamide derivatives: a new class of potent and selective "pheripheral-type" benzodiazepine receptor ligands 117
Novel, Highly Potent Adenosine Deaminase Inhibitors Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synhesis, Structure-Activity Relationships, and Molecular Modeling Studies 116
NOVEL KINASE INHIBITORS IN THYROID CANCER TREATMENT: SYNTHESIS AND BIOLOGICAL EVALUATION 113
Glioblastoma multiforme: antitumoral in vitro effect by induction of collapse of mitochondrial membrane potential 112
3-Aryl-1,2,4-triazino-4,3-abenzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists 111
Targeting the Translocator protein (TSPO) with 2-phenylindol-3-ylglyoxylamide derivatives 110
2-PHENYL[1,2,3]TRIAZOLO[1,2-a]BENZOTRIAZIN-1-ONE DERIVATIVES AS A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS 109
Translocator Protein 18-kDa: a promising target to treat neuroinflammation-related degenerative diseases 108
Progettazione e sintesi di nuovi derivati 2-fenilindol-3-ilgliossilamidici per un approfondimento delle relazioni struttura attività (SAR) di questa classe di ligandi potenti e selettivi per il PBR 107
Substituted 2-Arylindolglyoxylamides as Potent Translocator Protein (18 kDa) TSPO ligands: Synthesis and Biological Evaluation 107
Synthesis and Antiproliferative Activity of New Aminoalkyl Substituted Benzothiopyranoindoles 106
Synthesis and biological evaluation on human glioblastoma cells of novel pyrazolo[3,4-d]pyrimidine adenosine A(3) receptor antagonists. 106
"Sintesi e attività antiproliferativa di sistemi Pirido[3’,2’:5,6]tiopirano[4,3-c]pirazolici 2-aril sostituiti" 104
Synthesis and in vitro Antiproliferative Activity of New Substituted Benzo[3',2':5,6]thiopyrano[4,3-d]pyrimidines 99
"Synthesis of new indolo[3,2-c][1,8]naphthyridine derivatives as antiproliferative agents" 98
Dialkylaminoalkylindolonaphthyridines as potential antitumor agents: synthesis, cytotoxicity and DNA binding properties 98
Totale 15.406
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Categoria #
all - tutte 43.115
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 43.115
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021522 0 0 0 0 0 34 41 71 73 52 55 196
2021/20221.236 24 93 57 88 226 143 18 58 49 24 83 373
2022/20231.847 237 350 121 170 218 219 22 145 278 7 63 17
2023/20241.408 200 184 159 122 222 238 41 28 21 38 37 118
2024/20253.415 28 131 25 211 429 344 196 157 311 447 357 779
2025/20261.765 181 354 320 210 376 324 0 0 0 0 0 0
Totale 16.351