CINECA IRIS Institutional Research Information System

SIMORINI, FRANCESCA
 Distribuzione geografica
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Continente #
NA - Nord America 6.190
EU - Europa 3.589
AS - Asia 1.275
AF - Africa 110
OC - Oceania 26
SA - Sud America 9
Continente sconosciuto - Info sul continente non disponibili 1
Totale 11.200
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Nazione #
US - Stati Uniti d'America 6.008
IT - Italia 1.489
SE - Svezia 766
CN - Cina 527
DE - Germania 389
BG - Bulgaria 273
TR - Turchia 265
GB - Regno Unito 203
CA - Canada 181
VN - Vietnam 172
SG - Singapore 160
UA - Ucraina 129
FI - Finlandia 109
AT - Austria 73
IN - India 68
CI - Costa d'Avorio 56
HK - Hong Kong 48
CH - Svizzera 44
NG - Nigeria 30
RU - Federazione Russa 30
AU - Australia 24
FR - Francia 24
BE - Belgio 21
JP - Giappone 15
NL - Olanda 14
SN - Senegal 12
EG - Egitto 9
CZ - Repubblica Ceca 6
BR - Brasile 5
DK - Danimarca 4
IR - Iran 4
BJ - Benin 3
ID - Indonesia 3
IE - Irlanda 3
PK - Pakistan 3
PL - Polonia 3
EC - Ecuador 2
GR - Grecia 2
HU - Ungheria 2
JO - Giordania 2
NZ - Nuova Zelanda 2
AE - Emirati Arabi Uniti 1
AL - Albania 1
AZ - Azerbaigian 1
BD - Bangladesh 1
CL - Cile 1
CO - Colombia 1
EU - Europa 1
GE - Georgia 1
GL - Groenlandia 1
HR - Croazia 1
KR - Corea 1
KZ - Kazakistan 1
LT - Lituania 1
MC - Monaco 1
MY - Malesia 1
PT - Portogallo 1
SA - Arabia Saudita 1
Totale 11.200
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Città #
Woodbridge 920
Ann Arbor 847
Houston 687
Serra 564
Chandler 549
Milan 442
Fairfield 437
Ashburn 319
Sofia 273
Izmir 259
Beijing 202
Jacksonville 193
Seattle 178
Ottawa 173
Wilmington 170
New York 156
Cambridge 147
Boardman 125
London 122
Princeton 121
Nanjing 111
Lawrence 110
Dong Ket 103
Medford 79
Singapore 71
Vienna 62
Des Moines 61
Abidjan 56
Dearborn 56
Rome 54
Frankfurt am Main 51
Hong Kong 47
Bern 43
Rho 38
Los Angeles 36
Jüchen 32
Lagos 30
Kunming 29
Nanchang 29
Boulder 28
Bremen 28
Pune 26
Shenyang 26
Redwood City 25
Düsseldorf 24
Ogden 22
Brussels 21
Chicago 21
San Diego 20
Changsha 19
Nürnberg 19
Hebei 18
Tianjin 15
Aversa 13
Pisa 13
Sydney 13
Washington 13
Dakar 12
Norwalk 12
Florence 11
Hefei 11
Falls Church 10
Jiaxing 10
Orange 10
Dallas 9
Auburn Hills 8
Lancaster 8
Melbourne 8
San Francisco 8
Hangzhou 7
Helsinki 7
Brno 6
Santa Clara 6
Tappahannock 6
Toronto 6
Amsterdam 5
Caserta 5
Cecina 5
Jinan 5
Massa 5
Omaha 5
Vicopisano 5
Ankara 4
Augusta 4
Cascina 4
Indiana 4
Mumbai 4
Paris 4
Phoenix 4
Chiyoda-ku 3
Chongqing 3
Citta 3
Clifton 3
Cotonou 3
Guangzhou 3
Hyderabad 3
Kolkata 3
Lappeenranta 3
Lucca 3
Marseille 3
Totale 8.597
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Nome #
1,2-Benzisothiazole Derivatives Bearing 4-, 5-, or 6-Alkyl/arylcarboxamide Moieties Inhibit Carbonic Anhydrase Isoform IX (CAIX) and Cell Proliferation under Hypoxic Conditions 317
N, N-Dialkyl-2-phenylindol-3-ylglyoxylamides.A new class of potent and selective ligands at the Peripheral benzodiazepine receptor 204
Benzofuroxane Derivatives as Multi Effective Agents for the Treatment of Cardiovascular Diabetic Complications. Synthesis, Functional Evaluation, and Molecular Modeling Studies 200
Exploiting the Pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors, 181
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: a New Class of Selective Aldose Reductase Inhibitors 178
[1,2,4]Triazino[4,3-a]benzimidazole Acetic Acid Derivatives: A New Class of Selective Aldose Reductase Inhibitors 169
Deepening the Topology of the Translocator Protein Binding Site by Novel N,N-Dialkyl-2-arylindol-3-ylglyoxylamides 166
Identification of Anxiolytic/Nonsedative Agents among Indol-3-ylglyoxylamides Acting as Functionally Selective Agonists at the γ-Aminobutyric Acid-A (GABAA) α2 Benzodiazepine Receptor 161
Synthesis of a Novel Purine-Containing Heterocyclic Ring System: 8,10-Dimethylindolo[2',3':5,6][1,2,4]triazino[4,3-f]purine-9,11(8H,10H,13H)dione 147
TSPO-ligands prevent oxidative damage and inflammatory response in C6 glioma cells by neurosteroid synthesis 146
Refinement of Structure-activity Relationships of the Triazinobenzimidazole A1AR Antagonists 144
Geometrically Constrained Analogues N-Benzylindolylglyoxylylamides: [1,2,4]Triazino[4,3-a]benzimidazol-4(10H)-one Derivatives as Potential New Ligands at the Benzodiazepine Receptor. 143
5-Amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a Versatile Scaffold to Obtain Potent and Selective A3 Adenosine Receptor Antagonists 143
FACILE SYNTHESIS OF 3-SUBSTITUTED[1,2,4]TRIAZINO[3,4-F]PURINE-4,6,8-TRIONE DERIVATIVES 139
Benzo[d]isothiazoles and Matrix Metalloproteinases. Searching for Novel and Selective Inhibitors of MMP9 138
Recent Advances in the Development of Dual Topoisomerase I and II Inhibitors as Anticancer Drugs 138
Novel, Highly Potent Aldose Reductase Inhibitors:Cyano(2-oxo-2,3-dihydroindol-3-yl)acetic Acid Derivatives 135
“Synthesis and antiproliferative evaluation of new substituted Benzothiopyrano[4,3-c] condensed ring systems” 134
Benzothiopyranoindole-Based Antiproliferative Agents: Synthesis, Cytotoxicity, Nucleic Acids Interaction, and Topoisomerases Inhibition Properties. 134
Sulfonamides incorporating heteropolycyclic scaffolds show potent inhibitory action against carbonic anhydrase isoforms I, II, IX and XII 134
Medicinal chemistry of indolylglyoxylamide TSPO high affinity ligands with anxiolytic-like effects 130
An approach to novel fused triazole or tetrazole derivatives starting from Benzimidazo[1,2-a]quinazoline-5(7H)-one and 5,7-Dihydro-5-oxopyrido[3',2':5,6]pyrimido[1,2-a]benzimidazole 129
Novel N(2)-Substituted Pyrazolo[3,4-d]pyrimidine Adenosine A(3) Receptor Antagonists: Inhibition of A(3)-Mediated Human Glioblastoma Cell Proliferation (dagger) 129
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of non-camptothecin Topoisomerase I (Top1) inhibitors 126
Synthesis of novel pyrido[3',2':5,6]thiopyrano[3,2-b]indol-5(6H)-ones and 6H-pyrido[3',2':5,6]thiopyrano[4,3-b]quinolines,two new heterocyclic systems. 124
Studies in search for selective ligands for GABAA/BzR receptor subtypes: synthesis and biological evaluation of 4'-modified N-(benzyl)indol-3-ylglyoxylamides 124
Novel Potent and Selective Human Adenosine A3 Receptor Antagonists Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis and Biological Evaluation 123
Structure-Based Optimization of Tyrosine Kinase Inhibitor CLM3. Design, Synthesis, Functional Evaluation, and Molecular Modeling Studies. 122
Medicinal chemistry of indolylglyoxylamide GABAA/BzR high affinity ligands: identification of novel anxiolytic/non sedative agents 121
Synthesis of New Heterocyclic Ring Systems via [1,3,5]Triazino[1,2-a]benzimidazole Derivatives 119
Acetic acid aldose reductase inhibitors bearing a five-membered heterocyclic core with potent topical activity in a visual impairment rat model 119
Novel Pyrazolo[3,4-d]pyrimidine Derivatives as ATP-competitive Inhibitors of the Epidermal Growth Factor Receptor Protein Tyrosine Kinase 117
Tertiary amides with a five-membered heteroaromatic ring as new probes for the translocator protein 117
Pyrido[1,2-a]pyrimidin-4-one derivatives as a novel class of selective aldose reductase inhibitors exhibiting antioxidant activity 116
Naphtho[1,2-d]isothiazole Acetic Acid Derivatives as a Novel Class of Selective Aldose Reductase Inhibitors 115
Investigation of new 2-aryl substituted Benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors targeting vascular endothelial growth factor receptor 2 115
Pyrazolo[3,4,-d]pyrimidine-4-one Derivatives as Novel and Potent Inhibitors of Adenosine Deaminase 111
Small Molecules Containing the Benzo[d]isotiazole Ring System as Novel ATP-Competitive Inhibitors of Epidermal Growth Factor Receptor protein Tyrosine Kinase 110
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A(2B) adenosine receptor antagonists 110
Translocator protein (tspo) ligand residence time: a new parameter to predict neurosteroidogenic efficacy for n,n-dialkyl-2-arylindol-3-ylglyoxylamides (PIGAs) 110
Microwave-assisted Suzuki Coupling in Aqueous Media: a Useful Tool for the Synthesis of 3-Arylindazole Derivatives 109
Antitumoral effect by induction of collapse of mitochondrial membrane potential in Glioblastoma Multiforme cells 109
PIGA (N,N-Di-n-butyl-5-chloro-2-(4-chlorophenyl)indol-3-ylglyoxylamide), a new mitochondrial benzodiazepine-receptor ligand, induces apoptosis in C6 glioma cells 109
Novel N-substituted indol-3-ylglyoxylamides probing the LDi and L1L2 lipophilic regions of the benzodiazepine receptor site in search for subtype-selective ligands 109
Anxiolytic properties of a 2-phenylindolglyoxylamide TSPO ligand: Stimulation of in vitro neurosteroid production affecting GABA(A) receptor activity 108
Novel Irreversible Fluorescent Probes Targeting the 18 kDa Translocator Protein: Synthesis and Biological Characterization 106
Synthesis and Biological Evaluation of Pyrido[1,2-d]pyrimidin-4-one Derivatives as Novel Aldose Reductase Inhibitors Exhibiting Antioxidant Activity 105
Novel Aldose Reductase Acetic acid Inhibitors Bearing a Five Membered heterocyclic core 105
3-Aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: A Novel Template for the Design of Highly Selective A(2B) Adenosine Receptor Antagonists. 105
Benzothiopyranoindole- and pyridothiopyranoindole-based antiproliferative agents targeting topoisomerases 105
Refinement of the Benzodiazepine Receptor Site Topology by Structure-Activity Relationships of New N-(Heteroarylmethyl)indol-3-ylglyoxylamides 103
1-(PHENYLSULPHONAMIDO)-PYRAZOLE DERIVATIVES AS CARBONIC ANHYDRASE INHIBITORS. 102
Benzisothiazole-1,1-dioxide alkanoic acid derivatives as inhibitors of rat lens aldose reductase 102
Cell survival/death processes: Role of the mitochondrial Tranlocator Protein (TSPO) ligands 102
Geometrically Constrained Derivatives of Indolylglyoxylamides as Ligands Binding the GABAA/BzR Complex. 101
New fluorescent probes for the pheripheral-type benzodiazepine receptor: synthesis and biological application 100
N,N-Dialkyl-2-phenylindol-3- ylglyoxylamides. A New Class of Potent and Selective Ligands at the Peripheral Benzodiazepine Receptor 100
Synthesis and Benzodiazepine Receptor Affinity of Derivatives of the New Tricyclic Heteroaromatic System Pyrido[3’,2’:5,6]thiopyrano[4,3-c]pyridazin-3(2H,5H)-one 100
Novel Antitumoral Pyrazolopyrimidines Based on Inhibition of Protein Tyrosine Kinase 98
Acid derivatives of benzisothiazole-1,1-dioxide as inhibitors of rat lens aldose reductase 97
Nuovi derivati acidi acetici quali potenti inibitori dell’Aldoso Reduttasi 96
Synthesis of pyrrolo[3,4-c]pyridine derivatives possessing an acid group and their in vitro and in vivo evaluation as aldose reductase inhibitors 96
EFFECTS OF TSPO-LIGANDS ON MITOCHONDRIAL VOLUME AND MITOCHONDRIAL MEMBRANE POTENTIAL 95
A 2-phenylindol-3-ylglyoxylammide derivative, a new-synthesized peripheral benzodiazepine receptor ligand, induces apoptosis in rat C6 glioma cells 95
Synthesis and biological evaluation of Modified 2-Phenylindol-3-ylglyoxylamides as good candidates for the development of radioligands for the visualization of peripheral benzodiazepine receptor 95
Discovery of Pyrido[3′,2′:5,6]thiopyrano[4,3- d]pyrimidine-Based Antiproliferative Multikinase Inhibitors 94
2-Phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one derivatives as a new class of adenosine receptor antagonists 93
New oxazole and 1,2,4-oxadiazole derivatives as selective ligands at the Translocator Protein (TSPO) 92
Design, Synthesis, and Biological Evaluation of 3-Arylindazole Acetic Acid Derivatives as Aldose Reductase Inhibitors 91
New Fluorescent 2-Phenylindoleglyoxylamide Derivatives as Probes Targeting the Peripheral-Type Benzodiazepine Receptor: Design, Synthesis, and Biological Evaluation 91
Pyridopyrimidinone Derivatives as Novel Therapeutic Agents for the Topic Treatment of Vessel Walls Subjected to Percutaneous Intervention 90
Synthesis and local anaesthetic activity of some 7-amino-2-dialkylaminoalkylpyrrolo[3,4-c]pyridine derivatives 90
Exploiting the pyrazolo[3,4-d]pyrimidinone ring system as a useful template for the obtainment of potent adenosine deaminase inhibitors 89
Anxiolytic-like Effects of N,N-Dialkyl-2-phenylindol-3-ylglyoxylamides by Modulation of Translocator Protein Promoting Neurosteroid Biosynthesis 88
Design, synthesis, and biological evaluation of novel fluorescent probes targeting the Translocator Protein (18 kDa) (TSPO) 85
Glioblastoma multiforme: antitumoral in vitro effect by induction of collapse of mitochondrial membrane potential 80
Novel Pyrazolopyrimidine Derivatives as Therapeutic Agents for the Treatment of Medullary Thyroid Carcinoma 79
Tricyclic Sulfonamides Incorporating Benzothiopyrano[4,3-c]pyrazole and Pyridothiopyrano[4,3-c]pyrazole Effectively Inhibit a- and ß-Carbonic Anhydrase: X-ray Crystallography and Solution Investigations on 15 Isoforms 79
NOVEL KINASE INHIBITORS IN THYROID CANCER TREATMENT: SYNTHESIS AND BIOLOGICAL EVALUATION 77
Synthesis and Antiproliferative Activity of New Aminoalkyl Substituted Benzothiopyranoindoles 77
New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors 77
Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of noncamptothecin Topoisomerase I (top1) inhibitors 76
Targeting the Translocator protein (TSPO) with 2-phenylindol-3-ylglyoxylamide derivatives 74
2-(phenylsulphonamido)-pyrazole derivatives as carbonic anhydrase inhibitors 74
Novel Highly Potent Adenosine Deaminase Inhibitors Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synthesis, Structure-Activity Relationships and Molecular Modeling Studies 74
"Sintesi e attività antiproliferativa di sistemi Pirido[3’,2’:5,6]tiopirano[4,3-c]pirazolici 2-aril sostituiti" 73
Benzoxadiazole Derivatives: Atypical Inhibitors of Aldose Reductase 73
N,N-dialkyl-2-phenylindol-3-ylglyoxylylamide derivatives: a new class of potent and selective "pheripheral-type" benzodiazepine receptor ligands 72
Synthesis and biological evaluation on human glioblastoma cells of novel pyrazolo[3,4-d]pyrimidine adenosine A(3) receptor antagonists. 72
Substituted 2-Arylindolglyoxylamides as Potent Translocator Protein (18 kDa) TSPO ligands: Synthesis and Biological Evaluation 71
Novel, Highly Potent Adenosine Deaminase Inhibitors Containing the Pyrazolo[3,4-d]pyrimidine Ring System. Synhesis, Structure-Activity Relationships, and Molecular Modeling Studies 71
Dialkylaminoalkylindolonaphthyridines as potential antitumor agents: synthesis, cytotoxicity and DNA binding properties 70
Progettazione e sintesi di nuovi derivati 2-fenilindol-3-ilgliossilamidici per un approfondimento delle relazioni struttura attività (SAR) di questa classe di ligandi potenti e selettivi per il PBR 69
Refinement of the translocator protein pharmacophore/receptor model via structure-activity relationships of novel N,N-dialkylindolylglyoxylamides 69
"Synthesis of new indolo[3,2-c][1,8]naphthyridine derivatives as antiproliferative agents" 68
3-Aryl-1,2,4-triazino-4,3-abenzimidazol-4(10H)-one: a novel template for the design of highly selective A2B adenosine receptor antagonists 67
Synthesis and in vitro Antiproliferative Activity of New Substituted Benzo[3',2':5,6]thiopyrano[4,3-d]pyrimidines 66
Synthesis and benzodiazepine receptor activity of some 4,5-dihydro-1H-pyrazolo[4,3-c][1,8]naphthyridine derivatives. 65
"Facile sintesi di nuove molecole polieterocicliche a partire dal 2-guanidinobenzimidazolo" 63
2-PHENYL[1,2,3]TRIAZOLO[1,2-a]BENZOTRIAZIN-1-ONE DERIVATIVES AS A NEW CLASS OF ADENOSINE RECEPTOR ANTAGONISTS 60
Totale 10.889
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Categoria #
all - tutte 28.170
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 28.170
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.044 0 0 0 90 133 147 187 93 130 90 159 15
2020/2021917 175 33 54 44 89 34 41 71 73 52 55 196
2021/20221.236 24 93 57 88 226 143 18 58 49 24 83 373
2022/20231.847 237 350 121 170 218 219 22 145 278 7 63 17
2023/20241.408 200 184 159 122 222 238 41 28 21 38 37 118
2024/2025219 28 131 25 35 0 0 0 0 0 0 0 0
Totale 11.390