TUCCINARDI, TIZIANO
 Distribuzione geografica
Continente #
NA - Nord America 22.935
AS - Asia 11.169
EU - Europa 9.253
SA - Sud America 1.966
AF - Africa 436
OC - Oceania 21
Continente sconosciuto - Info sul continente non disponibili 9
Totale 45.789
Nazione #
US - Stati Uniti d'America 22.289
IT - Italia 3.874
SG - Singapore 3.499
CN - Cina 2.926
HK - Hong Kong 1.784
BR - Brasile 1.630
SE - Svezia 1.091
VN - Vietnam 1.070
DE - Germania 866
BG - Bulgaria 671
FR - Francia 551
CA - Canada 473
GB - Regno Unito 472
TR - Turchia 442
FI - Finlandia 393
RU - Federazione Russa 355
IN - India 308
KR - Corea 247
UA - Ucraina 234
JP - Giappone 202
AT - Austria 196
BD - Bangladesh 114
CH - Svizzera 113
NL - Olanda 99
AR - Argentina 98
IQ - Iraq 86
MX - Messico 77
CI - Costa d'Avorio 71
ID - Indonesia 68
BE - Belgio 67
ZA - Sudafrica 64
MA - Marocco 63
PK - Pakistan 59
CO - Colombia 56
EC - Ecuador 53
UZ - Uzbekistan 52
ES - Italia 49
PL - Polonia 47
SA - Arabia Saudita 46
SN - Senegal 44
VE - Venezuela 41
NG - Nigeria 34
CZ - Repubblica Ceca 31
EG - Egitto 31
PH - Filippine 28
IR - Iran 27
TN - Tunisia 27
KE - Kenya 23
TW - Taiwan 23
DZ - Algeria 22
GR - Grecia 21
PY - Paraguay 21
UY - Uruguay 21
IL - Israele 20
JM - Giamaica 20
TT - Trinidad e Tobago 20
CL - Cile 18
PE - Perù 18
AU - Australia 17
AE - Emirati Arabi Uniti 16
IE - Irlanda 16
JO - Giordania 16
MY - Malesia 16
NP - Nepal 16
KZ - Kazakistan 15
ET - Etiopia 14
RO - Romania 14
HU - Ungheria 11
LB - Libano 11
PT - Portogallo 11
AO - Angola 10
CR - Costa Rica 10
DO - Repubblica Dominicana 9
LT - Lituania 9
AL - Albania 8
AZ - Azerbaigian 8
GE - Georgia 8
TH - Thailandia 8
BB - Barbados 7
BJ - Benin 7
BY - Bielorussia 7
HN - Honduras 7
SY - Repubblica araba siriana 7
BO - Bolivia 6
KW - Kuwait 6
PA - Panama 6
PS - Palestinian Territory 6
BA - Bosnia-Erzegovina 5
KG - Kirghizistan 5
OM - Oman 5
RS - Serbia 5
SK - Slovacchia (Repubblica Slovacca) 5
AM - Armenia 4
BH - Bahrain 4
DK - Danimarca 4
EU - Europa 4
GY - Guiana 4
HR - Croazia 4
LK - Sri Lanka 4
SI - Slovenia 4
Totale 45.704
Città #
Woodbridge 2.308
Ashburn 2.289
Singapore 2.018
Fairfield 1.789
Ann Arbor 1.750
Hong Kong 1.747
Houston 1.483
San Jose 1.260
Dallas 1.196
Chandler 1.018
Serra 1.006
Santa Clara 925
Milan 785
Seattle 764
Sofia 670
Shanghai 665
Beijing 617
Wilmington 612
Cambridge 584
New York 471
Boardman 351
Princeton 337
Ottawa 329
Hefei 327
Los Angeles 325
Jacksonville 287
Lauterbourg 254
Izmir 252
Lawrence 249
Ho Chi Minh City 239
Seoul 223
Medford 217
Council Bluffs 207
Nanjing 184
Tokyo 172
Hanoi 167
Munich 158
Vienna 154
Dong Ket 146
Pisa 145
São Paulo 144
Des Moines 136
Helsinki 133
Redondo Beach 133
Istanbul 130
Rome 130
London 129
Marseille 126
Florence 118
San Diego 103
Buffalo 100
Dearborn 95
Boulder 93
Redwood City 87
Frankfurt am Main 86
Columbus 85
Nanchang 84
Lucca 82
The Dalles 80
Bern 78
Chicago 71
Abidjan 70
Rio de Janeiro 64
Orem 63
Turku 60
Belo Horizonte 55
Ogden 55
Livorno 51
Dakar 44
Brussels 42
Jüchen 42
San Francisco 42
Chennai 41
Tashkent 41
Düsseldorf 37
Casablanca 36
Guangzhou 36
Hebei 36
Kunming 36
Amsterdam 35
Nuremberg 35
Baghdad 34
Lagos 33
Norwalk 33
Falls Church 32
Brasília 31
Dhaka 31
Changsha 30
Pune 30
Shenyang 30
Washington 30
Zurich 30
Bremen 29
Da Nang 28
Denver 28
Hangzhou 28
Hyderabad 28
Jakarta 28
Jiaxing 28
Phoenix 28
Totale 32.393
Nome #
4-Aryliden-2-methyloxazol-5(4H)-one as a new scaffold for selective reversible MAGL inhibitors 329
Anticancer activity of euplotin C, isolated from the marine ciliate euplotes crassus, against human melanoma cells 284
GLUT1 and LOX inhibitors as perspective anticancer agents tackling glucose avidity and ECM remodeling in tumors 270
Phenylpropanoids and flavonoids from Phlomis kurdica as inhibitors of human lactate dehydrogenase. 265
Tenebrio molitor reared on different substrates: is it gluten free? 263
Human carbonyl reductase 1 as efficient catalyst for the reduction of glutathionylated aldehydes derived from lipid peroxidation 261
Receptor-based virtual screening evaluation for the identification of estrogen receptor β ligands 260
New activators of SIRT1 enzyme for the treatment of cardiovascular and cardiometabolic pathologies 249
The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives 248
Synthesis and biological evaluation of non-glucose glycoconjugated N-hydroyxindole class LDH inhibitors as anticancer agents 238
Aldose reductase differential inhibitors in green tea 237
Identification of Lactate Dehydrogenase 5 Inhibitors using Pharmacophore- Driven Consensus Docking 234
1,8-Naphthyridin-4-one derivatives as new ligands of A2A adenosine receptors. 230
Synthesis and Biological Evaluation of New Glycoconjugated LDH Inhibitors as Anticancer Agents 230
Nuovi attivatori dell’enzima SIRT1 per il trattamento delle patologie cardiovascolari e cardiometaboliche 224
Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system 224
Reliability analysis and optimization of the consensus docking approach for the development of virtual screening studies 224
Synthesis and antitumor evaluation of 1,8-naphthyridine-2-(1H)-on-3carboxamide derivatives as CB2 selective agonists 221
Identification of the first synthetic allosteric modulator of the CB2receptors and evidence of its efficacy for neuropathic pain relief 221
Growth performances, chemical composition, and microbiological loads of mealworm reared with brewery spent grains and bread leftovers 220
Development of terphenyl-2-methyloxazol-5(4H)-one derivatives as selective reversible MAGL inhibitors 220
A Virtual Screening Study for Lactate Dehydrogenase 5 Inhibitors by using a Pharmacophore-Based Approach 219
Structural optimization of 4-chlorobenzoylpiperidine derivatives for the development of potent, reversible and selective monoacylglycerol lipase (MAGL) inhibitors 219
Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor 216
Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors 215
Bifunctional Inhibitors as a New Tool To Reduce Cancer Cell Invasion by Impairing MMP-9 Homodimerization 214
Rational Development of MAGL Inhibitors 210
Synthesis of Anthranylaldoxime Derivatives as Estrogen Receptor Ligands and Computational Prediction of Binding Modes 209
Discovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitors 207
Identification of a new STAT3 dimerization inhibitor through a pharmacophore-based virtual screening approach 206
Synthesis and AT1 affinity evaluation of benzamidophenyl analogs of known AT1 receptor ligands with similar aromatic skeleton 205
Salicylaldoxime derivatives as new leads for the development of carbonic anhydrase inhibitors 203
Exosite inhibition of ADAMTS-5 by a glycoconjugated arylsulfonamide 202
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 202
Synthesis of stable analogues of geranylgeranyl diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition 202
Salicylaldoximes and anthranylaldoximes as alternatives to phenol-based estrogen receptor ligands 201
Rational design, synthesis, biological evaluation and labelling of selective cannabinoid CB2 receptor agonists as anticancer agents 201
Historical perspective of tumor glycolysis: a century with Otto Warburg 200
Dual Targeting of the Warburg Effect with a Glucose-Conjugated Lactate Dehydrogenase Inhibitor 200
COMPOUNDS INHIBITING THE ENZYME LACTATE DEHYDROGENASE (LDH), PHARMACEUTICAL COMPOSITIONS AND USES THEREOF 200
Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform a (LDH-A) as Starvation Agents against Cancer Cells 199
Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors 198
D3 dopamine receptor subtype: which binding modes for such different ligands?, 198
An overview of recent developments in GPCR modelling: methods and validation 197
Identification of new FYN kinase inhibitors using a FLAP-based approach 196
The Extra-Virgin Olive Oil Polyphenols Oleocanthal and Oleacein Counteract Inflammation-Related Gene and miRNA Expression in Adipocytes by Attenuating NF-κB Activation 196
Antiproliferative oxime derivatives that inhibit glucose transporter 1 (GLUT1) in cancer cells 195
Characterization of the Saffron Derivative Crocetin as an Inhibitor of Human Lactate Dehydrogenase 5 in the Antiglycolytic Approach against Cancer 195
Stereoselectivity of aldose reductase in the reduction of glutathionyl-hydroxynonanal adduct 195
5-Amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a Versatile Scaffold to Obtain Potent and Selective A3 Adenosine Receptor Antagonists 194
Dual Inhibitors of Matrix Metalloproteinases and Carbonic Anhydrases: Iminodiacetyl-Based Hydroxamate-Benzenesulfonamide Conjugates 194
Design, Synthesis, Biological Evaluation, and NMR Studies of a New Series of Arylsulfones As Selective and Potent Matrix Metalloproteinase-12 Inhibitors 192
Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors 192
Modification on the 1,2-dihydro-2-oxo-pyridine-3-carboxamide core to obtain multi-target modulators of endocannabinoid system 192
Computational studies of EGFR inhibitors: Docking, 3D-QSAR analysis and virtual screening evaluation 189
Development of a receptor-based 3D-QSAR study for the analysis of MMP2, MMP3, and MMP9 inhibitors 189
N-O-Isopropyl Sulfonamido-Based Hydroxamates as Matrix Metalloproteinase Inhibitors: Hit Selection and in Vivo Antiangiogenic Activity 188
D3 dopamine receptor subtype: which binding modes for such different ligands? 187
Nuovi agenti antivirali a struttura N-idrossiindrol-carbossamidica 186
MolBook UNIPI─Create, Manage, Analyze, and Share Your Chemical Data for Free 186
Highly Selective Salicylketoxime-Based Estrogen Receptor β Agonists Display Antiproliferative Activities in a Glioma Model 186
Former foodstuff products in Tenebrio molitor rearing: Effects on growth, chemical composition, microbiological load, and antioxidant status 186
Amber force field implementation, molecular modelling study, synthesis and MMP-1/MMP-2 inhibition profile of (R)- and (S)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamides 185
Dissecting the Activity of Catechins as Incomplete Aldose Reductase Differential Inhibitors through Kinetic and Computational Approaches 184
Cyclic Ketoximes as Estrogen Receptorβ Selective Agonists 184
Design, Synthesis, and Evaluation of GLUT Inhibitors 183
Design, synthesis and biological evaluation of bifunctional inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP) 183
Selective and potent agonists for estrogen receptor beta derived from molecular refinements of salicylaldoximes 182
Effects of different blanching treatments on microbiological profile and quality of the mealworm (Tenebrio molitor) 182
Olivetol- and Resorcinol-Anandamide “hybrids”: design, synthesis, binding and molecular modeling of potent cannabinoid receptor ligands 181
Assessing the differential action on cancer cells of LDH-A inhibitors based on the N-hydroxyindole-2-carboxylate (NHI) and malonic (Mal) scaffolds 181
Design of transthyretin amyloidosis inhibitors: A docking and virtual screening approach 180
Design, Synthesis and biological evaluation of new 1,8-naphthyridin-4(1h)-on-3-carboxamide and quinolin-4(1h)-on-3-carboxamide derivatives as CB2 selective agonists 179
Cannabinoid CB2/CB1 Selectivity. Receptor Modeling and Automated Docking Analysis 179
N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation 179
Liposomal delivery of a Pin1 inhibitor complexed with cyclodextrins as new therapy for high-grade serous ovarian cancer 179
Selective activators of estrogen receptor beta based on the aldoxime and ketoxime scaffolds 178
N-O-Isopropyl Sulfonamido-Based Hydroxamates: Design, Synthesis and Biological Evaluation of Selective Matrix Metalloproteinase-13 Inhibitors as Potential Therapeutic Agents for Osteoarthritis 178
Immunomodulatory properties of 1,2-dihydro-4-hydroxy-2-oxo-1,8-naphthyridine-3-carboxamide derivative VL15 178
Development of a Fingerprint-Based Scoring Function for the Prediction of the Binding Mode of Carbonic Anhydrase II Inhibitors 178
VenomPred 2.0: A Novel In Silico Platform for an Extended and Human Interpretable Toxicological Profiling of Small Molecules 176
Antibacterial and Hypoglycemic Diterpenoids from Salvia chamaedryoides 176
Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives 175
Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors 175
Different Binding Modes of Structurally Diverse Ligands for Human D3DAR 175
Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment 175
Computational Studies on Translocator Protein (TSPO) and its Ligands 174
Oxime-based inhibitors of glucose transporter 1 displaying antiproliferative effects in cancer cells 174
Natural compounds as inhibitors of lactate dehydrogenase 173
Novel aminopteroil-sulfonamide derivatives as inhibitors of dihydrofolate reductase and carbonic anhydrase, with potential anti tumor activity 172
A new development of matrix metalloproteinase inhibitors: twin hydroxamic acids as potent inhibitors of MMPs 172
Synthesis of sulfonamide-containing N-hydroxyindole-2-carboxylates as inhibitors of human lactate dehydrogenase-isoform 5 172
Salicylketoximes that target glucose transporter 1 restrict energy supply to lung cancer cells 172
Structure-Activity Relationship Studies of a New Series of Imidazo2,1-fpurinones as Potent and Selective A3 Adenosine Receptor Antagonists 171
Aryl-sulphonamidic dimers as metalloproteases inhibitors 170
Interactions of the carrier ligands of antidiabetic metal complexes with human serum albumin: A combined spectroscopic and separation approach with molecular modeling studies 170
Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors 170
Arylsulfonamide derivatives as metalloproteases inhibitors and their preparation, pharmaceutical compositions and use in the treatment of degenerative disorders 168
New Resorcinol-Anandamide "Hybrids" as Potent Cannabinoid Receptor Ligands Endowed with Antinociceptive Activity in Vivo 168
Analysis of Human Carbonic Anhydrase II: Docking Reliability and Receptor-Based 3D-QSAR Study 167
Totale 20.011
Categoria #
all - tutte 127.499
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 127.499


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021458 0 0 0 0 0 0 0 0 0 0 0 458
2021/20223.181 103 252 104 182 486 486 108 173 108 102 180 897
2022/20233.503 438 453 289 308 368 478 50 233 593 35 186 72
2023/20243.058 355 327 339 217 470 492 181 78 53 76 121 349
2024/20259.510 82 342 158 508 771 823 794 532 997 1.228 1.098 2.177
2025/202611.609 685 1.488 1.585 1.281 985 942 1.593 616 708 876 557 293
Totale 46.505