DANESI, ROMANO
 Distribuzione geografica
Continente #
NA - Nord America 36.357
EU - Europa 11.849
AS - Asia 4.166
AF - Africa 419
SA - Sud America 57
OC - Oceania 46
Continente sconosciuto - Info sul continente non disponibili 16
AN - Antartide 1
Totale 52.911
Nazione #
US - Stati Uniti d'America 35.568
IT - Italia 4.067
SE - Svezia 2.335
CN - Cina 2.265
BG - Bulgaria 1.379
DE - Germania 1.202
CA - Canada 773
GB - Regno Unito 693
UA - Ucraina 600
TR - Turchia 575
VN - Vietnam 540
FI - Finlandia 502
SG - Singapore 275
CI - Costa d'Avorio 258
CH - Svizzera 221
HK - Hong Kong 164
FR - Francia 148
IN - India 147
RU - Federazione Russa 143
AT - Austria 133
BE - Belgio 111
GR - Grecia 90
SN - Senegal 64
NG - Nigeria 62
PL - Polonia 47
NL - Olanda 42
AU - Australia 38
JP - Giappone 37
BR - Brasile 31
ES - Italia 26
KR - Corea 25
IR - Iran 23
ID - Indonesia 20
TW - Taiwan 20
IE - Irlanda 18
EG - Egitto 17
RO - Romania 17
EU - Europa 15
CZ - Repubblica Ceca 13
DK - Danimarca 13
HU - Ungheria 13
MX - Messico 13
MY - Malesia 11
PH - Filippine 11
TH - Thailandia 11
JO - Giordania 8
NZ - Nuova Zelanda 8
CL - Cile 7
CO - Colombia 7
DZ - Algeria 7
RS - Serbia 7
HR - Croazia 6
PT - Portogallo 6
AR - Argentina 5
IL - Israele 5
SA - Arabia Saudita 5
EC - Ecuador 4
IQ - Iraq 4
LK - Sri Lanka 4
NO - Norvegia 4
PK - Pakistan 4
AE - Emirati Arabi Uniti 3
BF - Burkina Faso 3
LU - Lussemburgo 3
DO - Repubblica Dominicana 2
LT - Lituania 2
LV - Lettonia 2
MA - Marocco 2
TG - Togo 2
UZ - Uzbekistan 2
ZA - Sudafrica 2
A1 - Anonimo 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BD - Bangladesh 1
BN - Brunei Darussalam 1
BO - Bolivia 1
EE - Estonia 1
GS - Georgia del Sud e Isole Sandwich Australi 1
KE - Kenya 1
LA - Repubblica Popolare Democratica del Laos 1
LB - Libano 1
MD - Moldavia 1
MK - Macedonia 1
NP - Nepal 1
OM - Oman 1
PA - Panama 1
PE - Perù 1
SI - Slovenia 1
SK - Slovacchia (Repubblica Slovacca) 1
UG - Uganda 1
UY - Uruguay 1
Totale 52.911
Città #
Woodbridge 5.734
Fairfield 4.246
Ann Arbor 4.203
Houston 3.985
Chandler 2.451
Ashburn 2.082
Seattle 1.779
Wilmington 1.508
Cambridge 1.449
Sofia 1.378
Serra 1.075
Milan 972
New York 852
Beijing 783
Jacksonville 770
Ottawa 730
Princeton 622
Lawrence 564
Izmir 547
Medford 508
Nanjing 448
Dearborn 361
Des Moines 333
Abidjan 258
Dong Ket 237
San Diego 219
Bern 207
Florence 189
Pisa 181
Nanchang 174
Boulder 159
Hong Kong 148
London 147
Redwood City 144
Vienna 130
Falls Church 129
Jüchen 126
Washington 124
Frankfurt am Main 117
Kunming 112
Brussels 101
Rome 96
Bremen 90
Hebei 86
Changsha 73
Los Angeles 73
Shenyang 73
Norwalk 65
Dakar 64
Düsseldorf 63
Lagos 62
Ogden 61
Hefei 58
Jiaxing 57
Pune 56
Tianjin 52
Boardman 49
Warsaw 38
Nürnberg 36
Auburn Hills 35
Marseille 34
Seacroft 34
Guangzhou 33
Indiana 33
Lancaster 33
Jinan 32
Orange 27
Phoenix 27
Shanghai 26
Detroit 25
Chicago 23
San Francisco 23
Lanzhou 22
Grafing 21
Hangzhou 20
Toronto 20
Helsinki 18
Rho 18
Livorno 17
Changchun 15
Tappahannock 15
Zhengzhou 15
Chengdu 14
Kocaeli 14
Singapore 14
Verona 14
Dallas 13
Edinburgh 13
Kilburn 13
Leawood 13
East Setauket 12
Budapest 11
Chiesina Uzzanese 11
Chongqing 11
Jakarta 10
Madrid 10
San Giuliano Terme 10
Stockholm 10
Chiswick 9
Naples 9
Totale 42.211
Nome #
Mathematical modeling of drug resistance due to KRAS mutation in colorectal cancer 375
A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity 302
PD-L1 mRNA expression in plasma-derived exosomes is associated with response to anti-PD-1 antibodies in melanoma and NSCLC 236
A rapid high-performance liquid chromatography method to measure linezolid and daptomycin concentrations in human plasma 206
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 205
Determination of mitotane and principal metabolite by a simple HPLC-UV method and its validation in human plasma sample 196
Exogenous doxorubicinol induces cardiotoxic effects in rats 191
VEGF-A polymorphisms predict short-term functional response to intravitreal ranibizumab in exudative age-related macular degeneration 190
A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients. 186
Antiproliferative and Proapoptotic Activity of Sunitinib on Endothelial and Anaplastic Thyroid Cancer Cells via Inhibition of Akt and ERK1/2 Phosphorylation and by Down-Regulation of Cyclin-D1. 182
Pharmacogenetic interaction analysis of VEGFR-2 and IL-8 polymorphisms in advanced breast cancer patients treated with paclitaxel and bevacizumab. 165
In vitro studies on gemcitabine combinations with other antiblastics 164
Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine 164
Variable correlation between 6-mercaptopurine metabolites in erythrocytes and hematologic toxicity: implications for drug monitoring in children with acute lymphoblastic leukemia 164
CLM29, a multi-target pyrazolopyrimidine derivative, has anti-neoplastic activity in medullary thyroid cancer in vitro and in vivo 160
Protein kinase inhibitors for the treatment of advanced and progressive radiorefractory thyroid tumors: From the clinical trials to the real life 160
Clinical, pharmacodynamic and pharmacokinetic results of a prospective phase II study on oral metronomic vinorelbine and dexamethasone in castration-resistant prostate cancer patients 159
First-line metronomic chemotherapy in a metastatic model of spontaneous canine tumours: a pilot study 157
Association of KRAS mutations in cell-free circulating tumor DNA with occurrence of resistance to TKIs in NSCLC 157
Antineoplastic activity of the multitarget tyrosine kinase inhibitors CLM3 and CLM94 in medullary thyroid cancer in vitro 156
Effect of SLCO1B3 haplotype on testosterone transport and clinical outcome in caucasian patients with androgen-independent prostatic cancer 155
An exploratory study on pharmacogenetics of inosine-monophosphate dehydrogenase II in peripheral mononuclear cells from liver-transplant recipients 155
Pharmacogenetics in Oncology 152
CLM3, a multitarget tyrosine kinase inhibitor with antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo 152
ABCB1 polymorphisms are associated with clozapine plasma levels in psychotic patients. 150
Embryonic stem cell pathways and chemotherapy response: an unexplored route. 150
Pharmacogenomics of gemcitabine in non-small-cell lung cancer and other solid tumors 149
Cancer stem cell epigenetics and chemoresistance 148
EGFR ligands as pharmacodynamic biomarkers in metastatic colorectal cancer patients treated with cetuximab and irinotecan 148
5-Fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer 146
Novel pyrazolopyrimidine derivatives as tyrosine kinase inhibitors with antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer. 146
Effects of Amiodarone, Thyroid Hormones and CYP2C9 and VKORC1 Polymorphisms on Warfarin Metabolism: A Review of the Literature. 145
Molecular and pathological characterization of the EZH2 rs3757441 single nucleotide polymorphism in colorectal cancer 145
Association of the CYP1B1*3 allele with survival in patients with prostate cancer receiving docetaxel 144
Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA 144
Cytochrome 450 1B1 (CYP1B1) polymorphisms associated with response to docetaxel in Castration-Resistant Prostate Cancer (CRPC) patients 144
Fructose-1,6-diphosphate reduces acute ECG changes due to doxorubicin in isolated rat heart 143
Clinical, pharmacokinetic and pharmacodynamic evaluations of metronomic UFT and cyclophosphamide plus celecoxib in patients with advanced refractory gastrointestinal cancers 143
Population pharmacokinetic analysis of 5-FU and 5-FDHU in colorectal cancer patients: search for biomarkers associated with gastro-intestinal toxicity 143
Doxorubicin cardiotoxicity in the dog: A morphofunctional study 142
Laser microdissection and primary cell cultures improve pharmacogenetic analysis in pancreatic adenocarcinoma. 142
null 142
A polymorphism in a transporter of testosterone is a determinant of androgen independence in prostate cancer 140
Antimicrobial peptides: therapeutic potential for the treatment of Candida infections. 140
Pharmacologic rationale for early G-CSF prophylaxis in cancer patients and role of pharmacogenetics in treatment optimization 139
The rs2071559 AA VEGFR-2 genotype frequency is significantly lower in neovascular age-related macular degeneration patients. 139
Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer. 139
The effects of the somatostatin analog octreotide on angiogenesis in vitro 138
The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors 138
The emerging role of histone lysine demethylases in prostate cancer. 137
Phosphonomethylphosphorylmethyl(oxy)-analogues of geranylgeranyl diphosphate as stable and selective geranylgeranyl protein transferase inhibitors 136
Carbogen and nicotinamide combined with unconventional radiotherapy in glioblastoma multiforme: a new modality treatment 135
Docetaxel plus oral metronomic cyclophosphamide: A phase II study with pharmacodynamic and pharmacogenetic analyses in castration-resistant prostate cancer patients 135
Antiangiogenic versus cytotoxic therapeutic approaches to human pancreas cancer: an experimental study with a vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor and gemcitabine 135
The effect of rhGM-CSF on the proliferation of osteogenic sarcoma cells 134
Association of a CYP17 polymorphism with overall survival in Caucasian patients with androgen-independent prostate cancer 134
Clinical and experimental evidence of inhibition of testosterone production by suramin 134
Oral and intravenously administered mTOR inhibitors for metastatic renal cell carcinoma: pharmacokinetic considerations and clinical implications 134
4'-Epidoxorubicin cardiotoxicity 133
A pilot study of suramin in the treatment of metastatic renal cell carcinoma 133
Pharmacokinetics, a main actor in a many-sided approach to severe 5-FU toxicity prediction 133
Pharmacogenetics of antiangiogenic and antineovascular therapies of age-related macular degeneration. 133
A PRACTICAL APPROACH TO THERAPEUTIC DRUG MONITORING OF IMATINIB IN PATIENTS AFFECTED BY CHRONIC MYELOID ELEUKEMIA. THE TIKLET PROTOCOL. 132
Chronic administration of suramin induces neurotoxicity in rats 131
Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines 131
Association of the hOCT1/ABCB1 genotype with efficacy and tolerability of imatinib in patients affected by chronic myeloid leukemia 131
DPYD IVS14+1G>A and 2846A>T genotyping for the prediction of severe fluoropyrimidine-related toxicity: a meta-analysis. 131
Suramin, a novel antitumor compound 130
Genetic analysis of cytidine deaminase (CDA) for the prediction of response to chemotherapy and survival in advanced non-small-cell lung cancer (NSCLC) patients treated with gemcitabine 130
Efficacy and safety of basiliximab in kidney transplantation 130
An aromatase polymorphism (g.132810C>T) predicts risk of bisphosphonate-related osteonecrosis of the jaw 130
Doxorubicin modifies plasma levels of immunoreactive atrial natriuretic factor 129
Pharmacokinetics and tolerance of nicotinamide combined with radiation therapy in patients with glioblastoma multiforme 129
Exploratory analysis of circulating pro-and anti-angiogenic factors in metastatic colorectal cancer (MCRC) patients, treated with GONO-folfoxiri plus bevacizumab (BV) 129
Case report of a successful treatment of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and MRSA/vancomycin-resistant Enterococcus faecium cholecystitis by daptomycin 129
Histone lysine demethylases in breast cancer. 129
CYP2D6 polymorphisms and the impact on tamoxifen therapy 128
Durable complete response to frontline docetaxel in an advanced prostate cancer patient with favourable CYP1B1 isoforms: suggestion for changing paradigms? 128
Optimized granulocyte colony-stimulating factor prophylaxis in adult cancer patients: from biological principles to clinical guidelines 128
Cholinergic toxic syndrome by the anticancer drug irinotecan: acetylcholinesterase does not play a major role 128
Inhibition of protein farnesylation enhances the chemotherapeutic efficacy of the novel geranylgeranyltransferase inhibitor BAL9611 in human colon cancer cells 128
A phase I study of continuous hepatic arterial infusion of Irinotecan in patients with locally advanced hepatocellular carcinoma 128
An improved HPLC method for therapeutic drug monitoring of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites in human plasma. 128
A new validated HPLC-UV method for therapeutic monitoring of daptomycin in comparison with reference Mass Spectrometry 128
The pharmacological bases of the antiangiogenic activity of paclitaxel 127
null 127
Methods: For studying pharmacogenetic profiles of combination chemotherapeutic drugs 127
General and cardiac toxicity of adriamycinol in rats 126
Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells 126
Administration interval and daptomycin toxicity: a case report of rhabdomyolysis 126
Molecular analysis of cell-free circulating DNA for the diagnosis of somatic mutations associated with resistance to tyrosine kinase inhibitors in non-small-cell lung cancer. 126
Polycomb genes are associated with response to imatinib in chronic myeloid leukemia 126
Impact of locoregional approaches to liver metastases in patients with colorectal cancer 125
Circulating amphiregulin (AR) plasma levels as surrogate pharmacodynamic markers of EGFR inhibition with cetuximab in metastatic colorectal cancer (MCRC) patients 125
5-fluorouracil administered as a 48-hour chronomodulated infusion in combination with leucovorin and cisplatin: a randomized phase II study in metastatic colorectal cancer 125
Exploratory analysis of circulating pro-and anti-angiogenic factors in metastatic colorectal cancer (MCRC) patients, treated with GONO-folfoxiri plus bevacizumab (BV) 124
Periodontal tissue disposition of azithromycin 124
Early changes in plasma DNA levels of mutant KRAS as a sensitive marker of response to chemotherapy in pancreatic cancer 124
Key concepts and critical issues on epoetin and filgrastim biosimilars. A position paper from the Italian Society of Hematology, Italian Society of Experimental Hematology, and Italian Group for Bone Marrow Transplantation 123
ABCB1 polymorphisms are associated with clozapine plasma levels in psychotic patients 123
Totale 14.671
Categoria #
all - tutte 134.589
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 134.589


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20192.765 0 0 0 0 0 0 0 0 0 0 1.549 1.216
2019/202011.178 1.232 911 1.007 764 1.076 1.356 1.280 918 1.072 638 718 206
2020/20215.148 416 359 366 249 542 252 335 613 509 438 335 734
2021/20226.462 150 395 247 391 1.028 1.012 228 333 262 246 348 1.822
2022/20237.361 1.009 844 475 696 834 1.026 61 566 1.258 48 480 64
2023/20244.755 658 584 712 327 747 1.033 150 264 92 111 77 0
Totale 53.995