DANESI, ROMANO
 Distribuzione geografica
Continente #
NA - Nord America 51.571
AS - Asia 20.882
EU - Europa 18.965
SA - Sud America 3.124
Continente sconosciuto - Info sul continente non disponibili 1.173
AF - Africa 766
OC - Oceania 62
AN - Antartide 1
Totale 96.544
Nazione #
US - Stati Uniti d'America 50.282
SG - Singapore 6.432
CN - Cina 5.610
IT - Italia 4.709
FI - Finlandia 4.445
HK - Hong Kong 3.845
BR - Brasile 2.597
SE - Svezia 2.468
VN - Vietnam 1.635
DE - Germania 1.557
BG - Bulgaria 1.382
GB - Regno Unito 1.032
CA - Canada 971
TR - Turchia 903
FR - Francia 819
RU - Federazione Russa 666
UA - Ucraina 643
KR - Corea 507
IN - India 424
JP - Giappone 367
CI - Costa d'Avorio 261
CH - Svizzera 239
BD - Bangladesh 218
AR - Argentina 182
AT - Austria 182
NL - Olanda 143
MX - Messico 131
BE - Belgio 122
ZA - Sudafrica 112
PL - Polonia 110
ID - Indonesia 105
IQ - Iraq 105
GR - Grecia 104
SA - Arabia Saudita 95
PK - Pakistan 94
ES - Italia 87
CO - Colombia 79
SN - Senegal 78
NG - Nigeria 69
UZ - Uzbekistan 67
EC - Ecuador 62
VE - Venezuela 62
MA - Marocco 57
AU - Australia 52
MY - Malesia 49
PH - Filippine 48
CL - Cile 43
EG - Egitto 43
PY - Paraguay 42
AE - Emirati Arabi Uniti 39
TT - Trinidad e Tobago 38
JO - Giordania 37
TH - Thailandia 37
IE - Irlanda 35
TW - Taiwan 32
KE - Kenya 30
CZ - Repubblica Ceca 29
JM - Giamaica 28
IL - Israele 27
TN - Tunisia 27
LT - Lituania 26
NP - Nepal 26
IR - Iran 25
CR - Costa Rica 24
RO - Romania 23
UY - Uruguay 23
HU - Ungheria 22
AZ - Azerbaigian 19
DK - Danimarca 18
DO - Repubblica Dominicana 18
DZ - Algeria 18
OM - Oman 18
BO - Bolivia 17
LB - Libano 16
EU - Europa 15
PT - Portogallo 15
BJ - Benin 14
PE - Perù 14
AL - Albania 13
BB - Barbados 13
PS - Palestinian Territory 13
RS - Serbia 13
HN - Honduras 12
KZ - Kazakistan 12
PA - Panama 12
BY - Bielorussia 10
HR - Croazia 10
NI - Nicaragua 10
ET - Etiopia 9
KG - Kirghizistan 9
SV - El Salvador 9
BH - Bahrain 8
LK - Sri Lanka 8
NO - Norvegia 8
NZ - Nuova Zelanda 8
GH - Ghana 7
GT - Guatemala 7
AM - Armenia 6
BA - Bosnia-Erzegovina 6
BW - Botswana 6
Totale 95.254
Città #
Woodbridge 5.734
Ashburn 4.845
Fairfield 4.242
Ann Arbor 4.203
Houston 4.013
Helsinki 3.874
Hong Kong 3.791
Singapore 3.498
Chandler 2.444
Santa Clara 2.097
Dallas 1.985
San Jose 1.917
Seattle 1.797
Wilmington 1.512
Cambridge 1.449
Sofia 1.378
Shanghai 1.270
Serra 1.079
Beijing 1.078
Milan 1.050
New York 1.001
Jacksonville 777
Ottawa 741
Boardman 725
Hefei 639
Princeton 620
Los Angeles 590
Lawrence 562
Izmir 551
Lauterbourg 515
Medford 508
Seoul 478
Nanjing 452
Council Bluffs 430
Ho Chi Minh City 367
Dearborn 361
Des Moines 334
Tokyo 302
London 297
Hanoi 277
Abidjan 261
Istanbul 252
Dong Ket 236
The Dalles 236
Pisa 234
Columbus 231
San Diego 225
Buffalo 224
Florence 213
São Paulo 213
Bern 207
Redondo Beach 201
Munich 183
Frankfurt am Main 179
Nanchang 174
Boulder 159
Vienna 149
Rome 145
Redwood City 144
Falls Church 131
Washington 130
Jüchen 126
Kunming 117
Brussels 110
Chicago 93
Bremen 90
Ogden 90
Hebei 86
Rio de Janeiro 86
Warsaw 84
Düsseldorf 82
Belo Horizonte 78
Dakar 78
Shenyang 78
Changsha 77
Turku 74
Phoenix 71
Lagos 67
Orem 67
Pune 67
Toronto 67
Norwalk 65
Nuremberg 63
Da Nang 61
Tashkent 59
Jiaxing 57
Tianjin 56
Atlanta 55
San Francisco 54
Denver 53
Guangzhou 53
Dhaka 52
Montreal 52
Brooklyn 50
Fuzhou 50
Stockholm 49
Brasília 47
Johannesburg 46
Jakarta 44
Mumbai 42
Totale 70.606
Nome #
Fructose-1,6-diphosphate reduces acute ECG changes due to doxorubicin in isolated rat heart 2.074
The influence of amrinone on cardiac toxicity induced by adriamycin in rats 2.030
Pharmacogenomics in non-small-cell lung cancer chemotherapy 793
Docetaxel plus oral metronomic cyclophosphamide: A phase II study with pharmacodynamic and pharmacogenetic analyses in castration-resistant prostate cancer patients 547
Corticosteroids in oncology: Use, overuse, indications, contraindications. An Italian Association of Medical Oncology (AIOM)/ Italian Association of Medical Diabetologists (AMD)/ Italian Society of Endocrinology (SIE)/ Italian Society of Pharmacology (SIF) multidisciplinary consensus position paper 515
Mathematical modeling of drug resistance due to KRAS mutation in colorectal cancer 452
A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity 355
PD-L1 mRNA expression in plasma-derived exosomes is associated with response to anti-PD-1 antibodies in melanoma and NSCLC 329
Drug-induced interstitial lung disease during cancer therapies: expert opinion on diagnosis and treatment 320
Pharmacogenomics in non-small-cell lung cancer chemotherapy 309
Pharmacogenetic interaction analysis of VEGFR-2 and IL-8 polymorphisms in advanced breast cancer patients treated with paclitaxel and bevacizumab. 303
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 298
Exogenous doxorubicinol induces cardiotoxic effects in rats 289
Procedimento attuato per mezzo di un elaboratore per la determinazione dei tempi di ritenzione e dei valori di concentrazione di analiti in una miscela 286
Determination of mitotane and principal metabolite by a simple HPLC-UV method and its validation in human plasma sample 285
A rapid high-performance liquid chromatography method to measure linezolid and daptomycin concentrations in human plasma 275
Antiangiogenic and anticolorectal cancer effects of metronomic irinotecan chemotherapy alone and in combination with semaxinib 274
A new validated HPLC-UV method for therapeutic monitoring of daptomycin in comparison with reference LC-MS/MS 269
Antiproliferative and Proapoptotic Activity of Sunitinib on Endothelial and Anaplastic Thyroid Cancer Cells via Inhibition of Akt and ERK1/2 Phosphorylation and by Down-Regulation of Cyclin-D1. 267
Gender, MGMT methylation, and levetiracetam plasma levels correlate with survival benefit in glioblastoma patients treated with adjuvant temozolomide: results from a non-interventional retrospective clinical study 259
VEGF-A polymorphisms predict short-term functional response to intravitreal ranibizumab in exudative age-related macular degeneration 256
Clinical, pharmacokinetic and pharmacodynamic evaluations of metronomic UFT and cyclophosphamide plus celecoxib in patients with advanced refractory gastrointestinal cancers 253
CLM29, a multi-target pyrazolopyrimidine derivative, has anti-neoplastic activity in medullary thyroid cancer in vitro and in vivo 248
First-line metronomic chemotherapy in a metastatic model of spontaneous canine tumours: a pilot study 245
A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients. 244
EGFR ligands as pharmacodynamic biomarkers in metastatic colorectal cancer patients treated with cetuximab and irinotecan 244
Clinical, pharmacodynamic and pharmacokinetic results of a prospective phase II study on oral metronomic vinorelbine and dexamethasone in castration-resistant prostate cancer patients 243
A selective antimuscarinic agent: pirenzepine. Review of its pharmacologic and clinical properties 240
Variable correlation between 6-mercaptopurine metabolites in erythrocytes and hematologic toxicity: implications for drug monitoring in children with acute lymphoblastic leukemia 238
ABCB1 polymorphisms are associated with clozapine plasma levels in psychotic patients. 236
Novel pyrazolopyrimidine derivatives as tyrosine kinase inhibitors with antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer. 231
Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine 227
CLM3, a multitarget tyrosine kinase inhibitor with antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo 227
ABCB1 polymorphisms are associated with clozapine plasma levels in psychotic patients 226
A new validated HPLC-UV method for therapeutic monitoring of daptomycin in comparison with reference Mass Spectrometry 225
Determination of mitotane and metabolite by a simple HPLC-UV method and application in plasma samples 221
In vitro studies on gemcitabine combinations with other antiblastics 221
Suramin, a novel antitumor compound 219
Molecular and pathological characterization of the EZH2 rs3757441 single nucleotide polymorphism in colorectal cancer 219
Association of the hOCT1/ABCB1 genotype with efficacy and tolerability of imatinib in patients affected by chronic myeloid leukemia 217
The hOCT1 and ABCB1 polymorphisms do not influence the pharmacodynamics of nilotinib in chronic myeloid leukemia 216
Periodontal tissue disposition of azithromycin 213
Effects of Amiodarone, Thyroid Hormones and CYP2C9 and VKORC1 Polymorphisms on Warfarin Metabolism: A Review of the Literature. 213
The effect of rhGM-CSF on the proliferation of osteogenic sarcoma cells 211
The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors 211
Pharmacogenetics in Oncology 210
Protein kinase inhibitors for the treatment of advanced and progressive radiorefractory thyroid tumors: From the clinical trials to the real life 210
A pilot study of suramin in the treatment of metastatic renal cell carcinoma 209
Carbogen and nicotinamide combined with unconventional radiotherapy in glioblastoma multiforme: a new modality treatment 209
CLM94, a novel cyclic amide with anti-VEGFR-2 and antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo 209
The rs2071559 AA VEGFR-2 genotype frequency is significantly lower in neovascular age-related macular degeneration patients. 209
Association of KRAS mutations in cell-free circulating tumor DNA with occurrence of resistance to TKIs in NSCLC 209
Effect of SLCO1B3 haplotype on testosterone transport and clinical outcome in caucasian patients with androgen-independent prostatic cancer 208
5-Fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer 208
Doxorubicin cardiotoxicity in the dog: A morphofunctional study 206
Pharmacokinetics and tolerance of nicotinamide combined with radiation therapy in patients with glioblastoma multiforme 206
4'-Epidoxorubicin cardiotoxicity 205
Population pharmacokinetic analysis of 5-FU and 5-FDHU in colorectal cancer patients: search for biomarkers associated with gastro-intestinal toxicity 205
Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA 204
The amount of activating EGFR mutations in circulating cell-free DNA is a marker to monitor osimertinib response 204
DPYD*6 plays an important role in fluoropyrimidine toxicity in addition to DPYD*2A and c.2846A>T: a comprehensive analysis in 1254 patients 204
A polymorphism in a transporter of testosterone is a determinant of androgen independence in prostate cancer 203
Synthesis of stable analogues of geranylgeranyl diphosphate possessing a (Z,E,E)-geranylgeranyl side chain, docking analysis, and biological assays for prenyl protein transferase inhibition 203
The c.480C>G polymorphism of hOCT1 influences imatinib clearance in patients affected by chronic myeloid leukemia. 203
Cancer stem cell epigenetics and chemoresistance 202
Pharmacogenomics of gemcitabine in non-small-cell lung cancer and other solid tumors 201
Pharmacogenetics of antiangiogenic and antineovascular therapies of age-related macular degeneration. 201
Early changes in plasma DNA levels of mutant KRAS as a sensitive marker of response to chemotherapy in pancreatic cancer 200
Overexpression of TK1 and CDK9 in plasma-derived exosomes is associated with clinical resistance to CDK4/6 inhibitors in metastatic breast cancer patients 200
General and cardiac toxicity of adriamycinol in rats 199
The effects of the somatostatin analog octreotide on angiogenesis in vitro 198
Linezolid in the central nervous system: Comparison between cerebrospinal fluid and plasma pharmacokinetics 198
An exploratory study on pharmacogenetics of inosine-monophosphate dehydrogenase II in peripheral mononuclear cells from liver-transplant recipients 198
Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer. 197
Antineoplastic activity of the multitarget tyrosine kinase inhibitors CLM3 and CLM94 in medullary thyroid cancer in vitro 197
Doxorubicin modifies plasma levels of immunoreactive atrial natriuretic factor 196
Molecular basis of resistance to azole antifungals. 196
Melanocortin Receptor-4 Gene Polymorphisms in Glioblastoma Patients Treated with Concomitant Radio-Chemotherapy 196
Population pharmacokinetics and probability of target attainment of meropenem in critically ill patients 196
DPYD IVS14+1G>A and 2846A>T genotyping for the prediction of severe fluoropyrimidine-related toxicity: a meta-analysis. 196
Impact of locoregional approaches to liver metastases in patients with colorectal cancer 195
5-Fluorouracil exposure in adjuvant chemotherapy regimens is significantly related to disease free survival in colorectal cancer patients 195
The emerging role of liquid biopsy in diagnosis, prognosis and treatment monitoring of pancreatic cancer 195
Polycomb genes are associated with response to imatinib in chronic myeloid leukemia 195
Phosphonomethylphosphorylmethyl(oxy)-analogues of geranylgeranyl diphosphate as stable and selective geranylgeranyl protein transferase inhibitors 194
Methods: For studying pharmacogenetic profiles of combination chemotherapeutic drugs 194
Therapeutic monitoring of Piperacillin in ICU patients 194
Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer 194
CYP2D6 polymorphisms and the impact on tamoxifen therapy 193
The heparan sulfate suleparoide inhibits rat corneal angiogenesis and in vitro neovascularization 193
PERIODONTAL TISSUE DISTRIBUTION OF CEFPODOXIME PROXETIL AND EFFICACY IN ACUTE ODONTOGENIC INFECTIONS 193
An aromatase polymorphism (g.132810C>T) predicts risk of bisphosphonate-related osteonecrosis of the jaw 193
A single nucleotide polymorphism in EZH2 predicts overall survival rate in patients with cholangiocarcinoma 193
Cytochrome 450 1B1 (CYP1B1) polymorphisms associated with response to docetaxel in Castration-Resistant Prostate Cancer (CRPC) patients 193
Chronic administration of suramin induces neurotoxicity in rats 192
Lung tissue penetration and plasma pharmacokinetics of azithromycin after multiple oral doses of 500 and 1000 mg in adults 191
Antimicrobial peptides: therapeutic potential for the treatment of Candida infections. 191
AR-V7 and AR-FL expression is associated with clinical outcome: a translational study in patients with castrate resistant prostate cancer 191
Antiangiogenic versus cytotoxic therapeutic approaches to human pancreas cancer: an experimental study with a vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor and gemcitabine 191
Embryonic stem cell pathways and chemotherapy response: an unexplored route. 189
Totale 27.227
Categoria #
all - tutte 268.702
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 268.702


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20226.296 0 395 247 391 1.027 1.006 228 332 262 244 347 1.817
2022/20237.336 1.005 840 474 693 833 1.022 61 565 1.253 48 478 64
2023/20245.397 658 583 710 326 747 1.031 150 263 91 111 183 544
2024/202517.549 112 680 122 965 1.702 1.795 1.332 1.063 1.794 2.287 1.962 3.735
2025/202622.801 1.228 2.950 2.339 1.717 1.745 1.675 2.737 895 4.714 1.416 932 453
2026/20271.605 872 733 0 0 0 0 0 0 0 0 0 0
Totale 96.544