CINECA IRIS Institutional Research Information System

LAPUCCI, ANNALINA
 Distribuzione geografica
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Continente #
NA - Nord America 6.997
AS - Asia 3.236
EU - Europa 2.784
SA - Sud America 472
AF - Africa 115
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 2
Totale 13.612
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Nazione #
US - Stati Uniti d'America 6.768
CN - Cina 1.061
SG - Singapore 897
IT - Italia 768
SE - Svezia 591
HK - Hong Kong 491
BR - Brasile 414
DE - Germania 402
BG - Bulgaria 259
TR - Turchia 256
CA - Canada 186
GB - Regno Unito 146
KR - Corea 143
UA - Ucraina 140
FI - Finlandia 137
RU - Federazione Russa 114
VN - Vietnam 110
IN - India 104
FR - Francia 61
CH - Svizzera 53
CI - Costa d'Avorio 39
JP - Giappone 30
BD - Bangladesh 25
BE - Belgio 23
IQ - Iraq 20
AR - Argentina 19
PL - Polonia 18
ZA - Sudafrica 18
SN - Senegal 17
SA - Arabia Saudita 15
ID - Indonesia 13
PK - Pakistan 13
MX - Messico 12
CZ - Repubblica Ceca 10
EC - Ecuador 10
NL - Olanda 10
TW - Taiwan 9
VE - Venezuela 9
GR - Grecia 8
UZ - Uzbekistan 8
AT - Austria 7
ES - Italia 7
LT - Lituania 7
PA - Panama 7
KE - Kenya 6
MA - Marocco 6
OM - Oman 6
PY - Paraguay 6
BJ - Benin 5
CO - Colombia 5
DO - Repubblica Dominicana 5
EG - Egitto 5
JO - Giordania 5
NG - Nigeria 5
TT - Trinidad e Tobago 5
CL - Cile 4
IE - Irlanda 4
JM - Giamaica 4
KZ - Kazakistan 4
AE - Emirati Arabi Uniti 3
AU - Australia 3
DZ - Algeria 3
LB - Libano 3
PS - Palestinian Territory 3
RS - Serbia 3
TN - Tunisia 3
AL - Albania 2
BB - Barbados 2
BY - Bielorussia 2
CR - Costa Rica 2
HN - Honduras 2
HU - Ungheria 2
IL - Israele 2
IR - Iran 2
MY - Malesia 2
NI - Nicaragua 2
NO - Norvegia 2
NP - Nepal 2
NZ - Nuova Zelanda 2
PT - Portogallo 2
QA - Qatar 2
RO - Romania 2
SC - Seychelles 2
UY - Uruguay 2
AZ - Azerbaigian 1
BF - Burkina Faso 1
BH - Bahrain 1
BN - Brunei Darussalam 1
BO - Bolivia 1
DK - Danimarca 1
ET - Etiopia 1
EU - Europa 1
GT - Guatemala 1
GY - Guiana 1
HR - Croazia 1
KG - Kirghizistan 1
KW - Kuwait 1
LK - Sri Lanka 1
LU - Lussemburgo 1
LY - Libia 1
Totale 13.603
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Città #
Woodbridge 931
Ann Arbor 730
Ashburn 608
Houston 538
Singapore 506
Santa Clara 502
Hong Kong 481
Chandler 464
Fairfield 426
Sofia 258
Serra 250
Shanghai 216
Beijing 207
Dallas 204
Izmir 196
Hefei 189
Milan 179
Jacksonville 175
Ottawa 160
Wilmington 158
Seattle 150
Seoul 139
New York 131
Cambridge 127
Princeton 113
Boardman 102
Lawrence 95
Medford 94
Nanjing 91
Los Angeles 73
Des Moines 69
Dearborn 67
Bern 51
Istanbul 51
Buffalo 46
Boulder 45
Dong Ket 43
The Dalles 40
Abidjan 39
Columbus 36
Nanchang 33
Redondo Beach 32
São Paulo 31
Council Bluffs 30
Marseille 30
Jüchen 27
Frankfurt am Main 26
Munich 26
Redwood City 26
London 25
Tokyo 25
Brussels 23
San Diego 21
Florence 20
Ogden 18
Tianjin 18
Changsha 17
Dakar 17
Kunming 17
Norwalk 17
Rome 17
Auburn Hills 16
Bremen 16
Grafing 15
Ho Chi Minh City 15
Nürnberg 15
Rio de Janeiro 15
Warsaw 15
Belo Horizonte 14
Turku 14
Shenyang 13
Fuzhou 12
Johannesburg 12
Baghdad 11
Brasília 11
Hebei 11
Hyderabad 11
Jakarta 11
Pune 11
Chicago 10
Hanoi 10
Jiaxing 10
Helsinki 9
Lancaster 9
Manchester 9
Orange 9
Phoenix 9
Brooklyn 8
Padova 8
Pisa 8
San Francisco 8
Tashkent 8
Toronto 8
Curitiba 7
Guangzhou 7
Hangzhou 7
Panama City 7
Taipei 7
Düsseldorf 6
Falkenstein 6
Totale 9.884
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Nome #
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 278
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 276
An approach to the knowledge of the steric requirements for alpha-adrenoreceptor direct activation. alpha-Adrenergic properties of new 3-piperidinols 219
Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications 212
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 212
SYNTHESIS AND EVALUATION OF THE PHARMACOLOGICAL ACTIVITY OF RIGID ANALOGUES OF SYMPATHOMIMETIC DERIVED FROM BICYCLO[2.2.1]HEPTANE 209
Role of the acyloxymethyl moiety in eliciting the adrenergic ß-blocking activity of 3-acyloxypropanolamines 194
Inhibition of [125] ET-1 binding to ETA receptors by salicilic acid dimers 194
Synthesis and AT1 affinity evaluation of benzamidophenyl analogs of known AT1 receptor ligands with similar aromatic skeleton 194
3-[(aryl)(4-fluorobenzyloxy)methyl]piperidine derivatives: high-affinity ligands for the serotonin transporter 193
Enantiopure 3-(arylmethylidene)aminoxy-2-methylpropionic acids: synthesis and antiinflammatory properties 190
CONFORMATIONALLY RESTRAINED ANALOGS OF SYMPATHOMIMETIC CATECHOLAMINES - SYNTHESIS AND ADRENERGIC ACTIVITY OF TETRAHYDROBENZOCYCLOHEPTENE DERIVATIVES 190
Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein 189
SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity 184
Structure of 2-hydroxy-3-isopropylaminopropyl 3,4-methylenedioxybenzoate hydrochloride 183
Sintesi e proprietà farmacologiche di analoghi semirigidi morfolinici e piperidinici di catecolamine simpatomimetiche. Modelli sterici per l'attivazione diretta dei recettori a- e ß-adrenergici. 182
3-(METHYLENEAMINOXY)METHYLPIPERIDINE DERIVATIVES AS UPTAKE INHIBITORS OF BIOGENIC-AMINES IN THE BRAIN SYNAPTOSOMAL FRACTION 181
Conformationally Restrained Analogs of Sympathomimetic Catecholamines. Synthesis, Conformational Analysis, and Adrenergic Activity of Isochroman Derivatives 180
SYNTHESIS, ANTIINFLAMMATORY ACTIVITY AND MOLECULAR-ORBITAL STUDIES OF A SERIES OF BENZYLIDENEAMINOXYPROPIONIC ACIDS SUBSTITUTED ON THE PHENYL RING 179
Novel Transthyretin Amyloid Fibril Formation Inhibitors: Synthesis, Biological Evaluation, and X-Ray Structural Analysis 173
MOLECULAR DESIGN, SYNTHESIS, AND ANTIINFLAMMATORY ACTIVITY OF A SERIES OF BETA-AMINOXYPROPIONIC ACIDS 171
(Z)-(Methyloxyiminomethyl)ethanolamines. Effects of the configuration around the iminic double bond on the beta-adrenergic affinity of moim-type beta-adrenergic blocking agents 170
2-(Methyleneaminoxy)methylmorpholine derivatives. Synthesis and antidepressant activity 169
Synthesis and in-vitro antitumour activity of new naphthyridine derivatives on human pancreatic cancer cells 169
3-(Methyleneaminoxy)methylpiperidine derivatives as uptake inhibitors of biogenic amines in the brain synaptosomal fraction 166
Synthesis and adrenergic ß-blocking activity of (oxypropanolamino)-substituted [(benzylideneamino)oxy]propanolamines 165
Conformationally restrained analogues of sympathomimetic catecholamines: Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro[naphthalen-1(2H)-2′,5′- morpholines] 163
Conformational effects on the activity of drugs. 7. Synthesis and pharmacological properties of 2-(p-nitrophenyl)-substituted morpholines 163
3-[(2-Ethoxyphenoxy)methyl]piperidine derivatives. Synthesis and antidepressant activity 162
1-(1-pirril)-3- ammino-2-propanoli N-sostituiti: sintesi e proprietà ß-adrenergiche 160
An interdisciplinary approach to the design of new structures active at the beta-adrenergic receptor. Aliphatic oxime ether derivatives 159
Synthesis and ß-Adrenergic Properties Of (Z)-N-[3-(Alkylamino)-2-hydroxypropilidene](aryl-methyloxy)amines: Effects Of The Configuration Around The Methyloxyiminomethyl(MOIM) Double Bond On The Biopharmacological Properties Of MOIM-type ß-Blocking Agents 158
4-ARYLPIPERIDINE DERIVATIVES AND USE THEREOF FOR PREPARING A MEDICAMENT FOR THE TREATMENT OF CNS DISEASE 158
Synthesis and β-adrenergic properties of tetrahydronaphthalene analogs of dichloroisoproterenol 156
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. 154
SYNTHESIS AND EVALUATION OF THE PHARMACOLOGICAL ACTIVITY OF RIGID ANALOGS OF SYMPATHOMIMETIC CATECHOLAMINES DERIVED FROM BICYCLO[2.2.1]HEPTANE 154
Conformational effects on the activity of drugs. Synthesis and adrenergic properties of 2-methyl-substituted 3-(3,4- dihydroxyphenyl)-3-piperidinols 151
Nuovi agenti ß-bloccanti: Derivati propanolamminici di eteri di ossime completamente alifatiche 149
Sintesi e proprietà beta-adrenergiche di [(benzilideneammino)ossi] propanolammine orto-ossipropanolammine sostituite chirali, 147
Therapeutic potential of sulindac hydroxamic acid against human pancreatic and colonic cancer cells 147
Synthesis and adrenergic beta-blocking activity of diastereoisomeric 3-(p-nitrophenyl)-6-methyl-3-piperidinols 145
Synthesis and affinity for serotonin and dopamine transporters of some benzophenone oxime ether derivatives 144
Synthesis and biological evaluation of (Hetero)aryl-methyloxyphenyl derivatives as potent P-glycoprotein modulating agents. 142
Allosteric inhibition of ET-1 binding to ETA receptors by aldoxime derivatives 141
Synthesis and adrenergic beta-blocking activity of ortho-, meta- and para-oxypropanolamino-substituted [(benzylideneamino)oxy]propanolamines. 140
Synthesis, Antifungal Activity, and Molecular Modeling Studies of New Inverted Oxime Ethers of Oxiconazole 140
Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD 140
Sintesi e attività recettoriale adrenergica di analoghi tetraidronaftalenici di catecolamine simpatomimetiche 139
Aryl-substituted methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: effects of some structural modifications on their biological properties 139
In vitro investigation of sulindac derivatives as potential anticancer agents 138
ROLE OF THE (ACYLOXY)METHYL MOIETY IN ELICITING THE ADRENERGIC BETA-BLOCKING ACTIVITY OF 3-(ACYLOXY)PROPANOLAMINES 138
CONFORMATIONAL EFFECTS ON THE ACTIVITY OF DRUGS .13. A REVISION OF PREVIOUSLY PROPOSED MODELS FOR THE ACTIVATION OF ALPHA-ADRENERGIC AND BETA-ADRENERGIC RECEPTORS 135
Effetti conformazionali sull'attività dei farmaci. Sintesi e proprietà farmacologiche di cis-2-aril-3-metilmorfoline 133
Uncommon formation of spiro orthoesters in the bromomethoxylation reaction of a 4-[(aroyloxy)methyl]-3-cephem derivative 133
Conformational effects on the activity of drugs. Synthesis and a and ß-adrenergic receptor activity of new terahydronaphthalene analogs of sympathomimetic catecholamines 132
Conformationally restrained analogs of sympathomimetic catecholamine. Synthesis and adrenergic activity of tetrahydrobenzocycloheptene derivatives 131
Synthesis and COX2 inhibitory properties of N-Phenyl-and N-benzyl-substituted amides of 2-(4-methylsulfonylphenyl)cyclopent-1-ene-1-carboxylic acid and of their pyrazole, thiophene, and isoxazole analogs 131
Conformational effects on the activity of drugs. 13. A revision of previously proposed models for the activation of a- and ß-adrenergic receptors 130
Effetti conformazionali sull'attività dei farmaci. Sintesi e valutazione dell'attività farmacologica di analoghi rigidi di catecolamine simpatomimetiche derivati dal norbornano 129
SYNTHESIS AND BETA-ADRENERGIC ACTIVITY OF A SERIES OF 3-(SUBSTITUTED-BENZYLIDENEAMINOXY)PROPANOLAMINE DERIVATIVES 127
Sintesi ed attività adrenergica di analoghi ciclici dell’1-(2,5-dimetossifenil)-2-amminoetanolo 125
Monoaryl-substituted Salicylaldoximes as Ligands for Estrogen Receptor Beta 124
SYNTHESIS AND BETA-ADRENERGIC ACTIVITY OF NEW COMPLETELY ALIPHATIC 3-(METHYLENEAMINOXY)PROPANOLAMINE DERIVATIVES 123
Chemistry of the Dihydrothiazine Ring Moiety of Cephalosporins. A Route to 3-Formoxymethyl-3-Cephem Derivatives 120
Synthesis and pharmacological activity of 1-phenyl-2-oxa-5-azabicyclo[4.4.0]decane derivatives 120
Synthesis and Biological Evaluation of 2'-Oxo-2,3-dihydro-3'H-spiro[chromene-4,5'-[1,3]oxazolidin]3'il]acetic Acid Derivatives as Aldose reductase Inhibitors 120
Sintesi ed attività α- e ß-adrenergica di analoghi benzocicloeptanici di catecolamine simpatomimetiche 117
Synthesis and antimicrobial properties of substituted ß-aminoxypropionyl penicillins and cephalosporins 117
Synthesis and inhibitory activity towards human leukocyte elastase of new 7 alpha-methoxy and 7 alpha-chloro (2-acyloxymethyl) cephem derivatives 116
Structure-activity relationship in cinnamamides. 3. Synthesis and anticonvulsant activity evaluation of some derivatives of (E)- and (Z)-m-(trifluoromethyl)cinnamamide 116
(E)-(methyloxyimino)acetamides as analogues of neuroleptic benzamides: Synthesis and D-2-dopaminergic binding affinity 115
Conformational effects on the activity of drugs. 11. Stereostructural models for the direct activation of the a- and ß-adrenergic receptor 112
Synthesis and evaluation of beta3-adrenergic affinity of new oximethereal derivative 111
Antiherpes virus agents: A review 111
Allosteric inhibition of (125I) ET-1 binding to ET(A) receptors by aldoxime and hydroxamic acid derivatives 110
Oximethereal piperidinic derivatives: synthesis and affinity for serotonin and dopamine transporters 108
An anomalous effect of N-isopropyl substitution in determining beta-adrenergic activity 106
SYNTHESIS AND AFFINITY FOR SEROTONIN TRANSPORTER OF NEW PIPERIDINE BASED BIVALENT LIGANDS 105
Conformational effects on the activity of drugs. 10. Synthesis, conformation, and pharmacological properties of 1-(2,5-dimethoxyphenyl)-2-aminoethanols and their morpholine analogues 105
null 103
Sintesi e affinità per il trasportatore della serotonina di nuovi derivati piperidinici ossimeterei 100
CONFORMATIONAL EFFECTS ON DRUG ACTIVITY .6. SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF 2-(PARANITROPHENYL) SUBSTITUTED MORPHOLINES 100
Synthesis and binding affinity at beta-adrenergic receptors of semirigid dichloroisoproterenol analogues, 98
Sintesi e proprietà alfa-adrenergiche di derivati cromanici, quali analoghi conformazionalmente ristretti dell’1-(2,5-dimetossifenil)-2-amminoetanolo 97
Synthesis and ß-adrenergic properties of tetrahydronaphthalene analogs of dichloroisoproterenol 95
Acidi benzilideneamminossipropionici sostituiti sul fenile. Sintesi e proprietà antiinfiammatorie. 95
Conformationally restrained analogues of sympathomimetic catecholamines. Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro[naphthalen-1(2H)-2',5'-morpholines] 94
Synthesis and pharmacological properties of cis-2-(2,5-dimethoxyphenyl)-3-methylmorpholine and its N-isopropyl derivative 92
Sintesi e proprietà inibitrici nei confronti delle cicloossigenasi di ammidi dell'acido 2-(4-metilsulfonilfenil)-1-ciclopentenico e di suoi analoghi eteroaromatici 87
Derivati della 3-imminossimetilpiperidina inibitori dell’uptake delle monoammine nelle frazioni sinaptosomiali cerebrali. 84
Synthesis and stereochemistry of (Z)- and (E)-(3,4,5-trimethoxy)-a,ß-dimethylcinnamic acids and diastereoisomeric intermediate ß-hydroxy esters 84
Derivati 4-arilpiperidinici e loro uso per la preparazione di un medicamento per il trattamento di disordini del SNC 81
Synthesis and biological evaluation of sulindac derivatives as potential anticancer agents 81
Sintesi, conformazione e proprietà farmacologiche di 1-(2,5-dimetossi fenil)-2-amminoetanoli e dei loro analoghi morfolinici. Un contributo alla conoscenza delle richieste steriche del recettore a-adrenergico 76
Sintesi e stereochimica degli acidi (Z)- e (E)-(3,4,5-trimetossi)-alfa,beta-dimetilcinnamico e dei beta-idrossiesteri diastereoisomeri intermedi. 75
2-Imminossimetil morfoline attive sul sistema nervoso centrale. Sintesi e proprietà antidepressive. 75
Synthesis, molecular docking and binding studies of selective serotonin transporter inhibitors 67
Nuovi derivati piperidinici: sintesi e proprietà biologiche 59
Totale 13.754
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Categoria #
all - tutte 35.920
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 35.920
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021384 0 0 0 0 0 32 52 80 54 51 24 91
2021/20221.160 22 80 17 91 227 135 26 52 49 42 77 342
2022/20231.328 195 154 105 142 136 194 16 83 210 11 70 12
2023/2024848 128 91 113 47 95 155 38 30 13 21 24 93
2024/20253.124 14 119 45 196 384 324 294 196 275 371 352 554
2025/20261.577 259 390 377 234 253 64 0 0 0 0 0 0
Totale 13.754