CINECA IRIS Institutional Research Information System

LAPUCCI, ANNALINA
 Distribuzione geografica
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Continente #
NA - Nord America 7.836
AS - Asia 3.742
EU - Europa 2.946
SA - Sud America 499
Continente sconosciuto - Info sul continente non disponibili 144
AF - Africa 123
OC - Oceania 6
Totale 15.296
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Nazione #
US - Stati Uniti d'America 7.588
SG - Singapore 1.173
CN - Cina 1.106
IT - Italia 787
SE - Svezia 593
HK - Hong Kong 504
BR - Brasile 432
DE - Germania 412
BG - Bulgaria 259
TR - Turchia 258
CA - Canada 194
VN - Vietnam 188
FI - Finlandia 156
GB - Regno Unito 155
FR - Francia 149
KR - Corea 145
UA - Ucraina 141
IN - India 121
RU - Federazione Russa 114
JP - Giappone 71
CH - Svizzera 53
CI - Costa d'Avorio 39
BD - Bangladesh 34
BE - Belgio 23
IQ - Iraq 22
ZA - Sudafrica 21
AR - Argentina 20
PL - Polonia 19
SN - Senegal 17
ID - Indonesia 16
MX - Messico 16
SA - Arabia Saudita 16
CZ - Repubblica Ceca 13
PK - Pakistan 13
VE - Venezuela 13
NL - Olanda 12
EC - Ecuador 10
ES - Italia 10
TW - Taiwan 10
UZ - Uzbekistan 10
AT - Austria 9
GR - Grecia 8
JO - Giordania 7
KE - Kenya 7
LT - Lituania 7
PA - Panama 7
PY - Paraguay 7
CO - Colombia 6
MA - Marocco 6
OM - Oman 6
BJ - Benin 5
CL - Cile 5
DO - Repubblica Dominicana 5
EG - Egitto 5
JM - Giamaica 5
KZ - Kazakistan 5
NG - Nigeria 5
TN - Tunisia 5
TT - Trinidad e Tobago 5
DZ - Algeria 4
IE - Irlanda 4
MY - Malesia 4
PS - Palestinian Territory 4
AE - Emirati Arabi Uniti 3
AU - Australia 3
BY - Bielorussia 3
CR - Costa Rica 3
KH - Cambogia 3
LB - Libano 3
NI - Nicaragua 3
PT - Portogallo 3
RS - Serbia 3
UY - Uruguay 3
AL - Albania 2
AZ - Azerbaigian 2
BB - Barbados 2
GT - Guatemala 2
HN - Honduras 2
HU - Ungheria 2
IL - Israele 2
IR - Iran 2
MG - Madagascar 2
NO - Norvegia 2
NP - Nepal 2
NZ - Nuova Zelanda 2
PH - Filippine 2
QA - Qatar 2
RO - Romania 2
SC - Seychelles 2
SK - Slovacchia (Repubblica Slovacca) 2
BF - Burkina Faso 1
BH - Bahrain 1
BN - Brunei Darussalam 1
BO - Bolivia 1
BZ - Belize 1
DK - Danimarca 1
ET - Etiopia 1
EU - Europa 1
GE - Georgia 1
GY - Guiana 1
Totale 15.138
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Città #
Woodbridge 931
Ann Arbor 730
Ashburn 679
Singapore 640
Houston 540
Santa Clara 512
Hong Kong 492
Chandler 464
Fairfield 426
San Jose 382
Sofia 258
Serra 250
Beijing 218
Shanghai 216
Dallas 214
Izmir 196
Hefei 189
Milan 181
Jacksonville 175
Ottawa 160
Wilmington 159
Seattle 151
Seoul 139
New York 137
Cambridge 127
Princeton 114
Boardman 102
Lawrence 95
Medford 94
Nanjing 91
Lauterbourg 81
Los Angeles 75
Des Moines 71
Dearborn 67
Tokyo 65
Council Bluffs 64
Istanbul 53
Bern 51
Buffalo 47
Boulder 45
Dong Ket 43
Ho Chi Minh City 41
The Dalles 40
Abidjan 39
Columbus 36
Nanchang 33
Redondo Beach 32
Frankfurt am Main 31
São Paulo 31
Hanoi 30
Marseille 30
Helsinki 28
Jüchen 27
Munich 26
Redwood City 26
London 25
Brussels 23
Rome 21
San Diego 21
Florence 20
Ogden 18
Tianjin 18
Changsha 17
Dakar 17
Kunming 17
Norwalk 17
Auburn Hills 16
Bremen 16
Warsaw 16
Grafing 15
Nürnberg 15
Orem 15
Rio de Janeiro 15
Belo Horizonte 14
Manchester 14
Turku 14
Chicago 13
Johannesburg 13
Shenyang 13
Atlanta 12
Baghdad 12
Fuzhou 12
Jakarta 12
Brasília 11
Hebei 11
Hyderabad 11
Pune 11
Jiaxing 10
Lancaster 10
Phoenix 10
Pisa 10
Tashkent 10
Toronto 10
Orange 9
San Francisco 9
Secaucus 9
Brooklyn 8
Chennai 8
Padova 8
Stockholm 8
Totale 10.788
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Nome #
Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme 304
Synthesis of Novel 3,5-Disubstituted-2-oxindole Derivatives As Antitumor Agents against Human Nonsmall Cell Lung Cancer 299
Synthesis and biological evaluation of (Hetero)aryl-methyloxyphenyl derivatives as potent P-glycoprotein modulating agents. 273
Locking PDK1 in DFG-out conformation through 2-oxo-indole containing molecules: Another tools to fight glioblastoma 239
An approach to the knowledge of the steric requirements for alpha-adrenoreceptor direct activation. alpha-Adrenergic properties of new 3-piperidinols 237
Synthesis and evaluation of multi-functional NO-donor/insulin-secretagogue derivatives for the treatment of type II diabetes and its cardiovascular complications 236
SYNTHESIS AND EVALUATION OF THE PHARMACOLOGICAL ACTIVITY OF RIGID ANALOGUES OF SYMPATHOMIMETIC DERIVED FROM BICYCLO[2.2.1]HEPTANE 225
Role of the acyloxymethyl moiety in eliciting the adrenergic ß-blocking activity of 3-acyloxypropanolamines 216
Inhibition of [125] ET-1 binding to ETA receptors by salicilic acid dimers 211
Synthesis and AT1 affinity evaluation of benzamidophenyl analogs of known AT1 receptor ligands with similar aromatic skeleton 207
3-[(aryl)(4-fluorobenzyloxy)methyl]piperidine derivatives: high-affinity ligands for the serotonin transporter 206
SAR study on arylmethyloxyphenyl scaffold: Looking for a P-gp nanomolar affinity 203
Synthesis and In Vivo Imaging of N-(3-[11C]Methoxybenzyl)-2-(3-Methoxyphenyl)ethylaniline as a Potential Targeting Agent for P-glycoprotein 203
Enantiopure 3-(arylmethylidene)aminoxy-2-methylpropionic acids: synthesis and antiinflammatory properties 202
CONFORMATIONALLY RESTRAINED ANALOGS OF SYMPATHOMIMETIC CATECHOLAMINES - SYNTHESIS AND ADRENERGIC ACTIVITY OF TETRAHYDROBENZOCYCLOHEPTENE DERIVATIVES 201
3-(METHYLENEAMINOXY)METHYLPIPERIDINE DERIVATIVES AS UPTAKE INHIBITORS OF BIOGENIC-AMINES IN THE BRAIN SYNAPTOSOMAL FRACTION 199
Sintesi e proprietà farmacologiche di analoghi semirigidi morfolinici e piperidinici di catecolamine simpatomimetiche. Modelli sterici per l'attivazione diretta dei recettori a- e ß-adrenergici. 197
Structure of 2-hydroxy-3-isopropylaminopropyl 3,4-methylenedioxybenzoate hydrochloride 195
Novel Transthyretin Amyloid Fibril Formation Inhibitors: Synthesis, Biological Evaluation, and X-Ray Structural Analysis 195
(Z)-(Methyloxyiminomethyl)ethanolamines. Effects of the configuration around the iminic double bond on the beta-adrenergic affinity of moim-type beta-adrenergic blocking agents 192
4-ARYLPIPERIDINE DERIVATIVES AND USE THEREOF FOR PREPARING A MEDICAMENT FOR THE TREATMENT OF CNS DISEASE 191
Conformationally Restrained Analogs of Sympathomimetic Catecholamines. Synthesis, Conformational Analysis, and Adrenergic Activity of Isochroman Derivatives 189
MOLECULAR DESIGN, SYNTHESIS, AND ANTIINFLAMMATORY ACTIVITY OF A SERIES OF BETA-AMINOXYPROPIONIC ACIDS 188
SYNTHESIS, ANTIINFLAMMATORY ACTIVITY AND MOLECULAR-ORBITAL STUDIES OF A SERIES OF BENZYLIDENEAMINOXYPROPIONIC ACIDS SUBSTITUTED ON THE PHENYL RING 188
SYNTHESIS AND EVALUATION OF THE PHARMACOLOGICAL ACTIVITY OF RIGID ANALOGS OF SYMPATHOMIMETIC CATECHOLAMINES DERIVED FROM BICYCLO[2.2.1]HEPTANE 185
3-(Methyleneaminoxy)methylpiperidine derivatives as uptake inhibitors of biogenic amines in the brain synaptosomal fraction 181
Synthesis and in-vitro antitumour activity of new naphthyridine derivatives on human pancreatic cancer cells 180
2-(Methyleneaminoxy)methylmorpholine derivatives. Synthesis and antidepressant activity 178
Conformational effects on the activity of drugs. 7. Synthesis and pharmacological properties of 2-(p-nitrophenyl)-substituted morpholines 178
Targeting the upregulated PI3K-PDK1-Akt pathway: a drug discovery approach of treating cancer. 177
An interdisciplinary approach to the design of new structures active at the beta-adrenergic receptor. Aliphatic oxime ether derivatives 177
Synthesis and adrenergic ß-blocking activity of (oxypropanolamino)-substituted [(benzylideneamino)oxy]propanolamines 176
1-(1-pirril)-3- ammino-2-propanoli N-sostituiti: sintesi e proprietà ß-adrenergiche 175
Conformationally restrained analogues of sympathomimetic catecholamines: Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro[naphthalen-1(2H)-2′,5′- morpholines] 174
3-[(2-Ethoxyphenoxy)methyl]piperidine derivatives. Synthesis and antidepressant activity 174
Synthesis and β-adrenergic properties of tetrahydronaphthalene analogs of dichloroisoproterenol 171
Synthesis and ß-Adrenergic Properties Of (Z)-N-[3-(Alkylamino)-2-hydroxypropilidene](aryl-methyloxy)amines: Effects Of The Configuration Around The Methyloxyiminomethyl(MOIM) Double Bond On The Biopharmacological Properties Of MOIM-type ß-Blocking Agents 169
Nuovi agenti ß-bloccanti: Derivati propanolamminici di eteri di ossime completamente alifatiche 165
Sintesi e proprietà beta-adrenergiche di [(benzilideneammino)ossi] propanolammine orto-ossipropanolammine sostituite chirali, 165
Therapeutic potential of sulindac hydroxamic acid against human pancreatic and colonic cancer cells 165
Conformational effects on the activity of drugs. Synthesis and adrenergic properties of 2-methyl-substituted 3-(3,4- dihydroxyphenyl)-3-piperidinols 163
Aryl-substituted methyleneaminoxymethyl (MAOM) analogues of diarylcyclopentenyl cyclooxygenase-2 inhibitors: effects of some structural modifications on their biological properties 163
Synthesis and adrenergic beta-blocking activity of diastereoisomeric 3-(p-nitrophenyl)-6-methyl-3-piperidinols 159
Synthesis and pharmacological evaluation of multifunctional tacrine derivatives against several disease pathways of AD 159
Synthesis and adrenergic beta-blocking activity of ortho-, meta- and para-oxypropanolamino-substituted [(benzylideneamino)oxy]propanolamines. 158
Allosteric inhibition of ET-1 binding to ETA receptors by aldoxime derivatives 157
In vitro investigation of sulindac derivatives as potential anticancer agents 152
Synthesis and affinity for serotonin and dopamine transporters of some benzophenone oxime ether derivatives 151
Sintesi e attività recettoriale adrenergica di analoghi tetraidronaftalenici di catecolamine simpatomimetiche 150
Synthesis, Antifungal Activity, and Molecular Modeling Studies of New Inverted Oxime Ethers of Oxiconazole 149
CONFORMATIONAL EFFECTS ON THE ACTIVITY OF DRUGS .13. A REVISION OF PREVIOUSLY PROPOSED MODELS FOR THE ACTIVATION OF ALPHA-ADRENERGIC AND BETA-ADRENERGIC RECEPTORS 149
Effetti conformazionali sull'attività dei farmaci. Sintesi e proprietà farmacologiche di cis-2-aril-3-metilmorfoline 148
Conformational effects on the activity of drugs. Synthesis and a and ß-adrenergic receptor activity of new terahydronaphthalene analogs of sympathomimetic catecholamines 148
Sintesi ed attività adrenergica di analoghi ciclici dell’1-(2,5-dimetossifenil)-2-amminoetanolo 147
ROLE OF THE (ACYLOXY)METHYL MOIETY IN ELICITING THE ADRENERGIC BETA-BLOCKING ACTIVITY OF 3-(ACYLOXY)PROPANOLAMINES 147
Conformational effects on the activity of drugs. 13. A revision of previously proposed models for the activation of a- and ß-adrenergic receptors 146
Effetti conformazionali sull'attività dei farmaci. Sintesi e valutazione dell'attività farmacologica di analoghi rigidi di catecolamine simpatomimetiche derivati dal norbornano 145
Synthesis and COX2 inhibitory properties of N-Phenyl-and N-benzyl-substituted amides of 2-(4-methylsulfonylphenyl)cyclopent-1-ene-1-carboxylic acid and of their pyrazole, thiophene, and isoxazole analogs 145
Uncommon formation of spiro orthoesters in the bromomethoxylation reaction of a 4-[(aroyloxy)methyl]-3-cephem derivative 143
Conformationally restrained analogs of sympathomimetic catecholamine. Synthesis and adrenergic activity of tetrahydrobenzocycloheptene derivatives 140
Synthesis and pharmacological activity of 1-phenyl-2-oxa-5-azabicyclo[4.4.0]decane derivatives 140
SYNTHESIS AND BETA-ADRENERGIC ACTIVITY OF NEW COMPLETELY ALIPHATIC 3-(METHYLENEAMINOXY)PROPANOLAMINE DERIVATIVES 138
Monoaryl-substituted Salicylaldoximes as Ligands for Estrogen Receptor Beta 138
Synthesis and Biological Evaluation of 2'-Oxo-2,3-dihydro-3'H-spiro[chromene-4,5'-[1,3]oxazolidin]3'il]acetic Acid Derivatives as Aldose reductase Inhibitors 138
SYNTHESIS AND BETA-ADRENERGIC ACTIVITY OF A SERIES OF 3-(SUBSTITUTED-BENZYLIDENEAMINOXY)PROPANOLAMINE DERIVATIVES 137
Sintesi ed attività α- e ß-adrenergica di analoghi benzocicloeptanici di catecolamine simpatomimetiche 132
Synthesis and antimicrobial properties of substituted ß-aminoxypropionyl penicillins and cephalosporins 131
Synthesis and inhibitory activity towards human leukocyte elastase of new 7 alpha-methoxy and 7 alpha-chloro (2-acyloxymethyl) cephem derivatives 130
Structure-activity relationship in cinnamamides. 3. Synthesis and anticonvulsant activity evaluation of some derivatives of (E)- and (Z)-m-(trifluoromethyl)cinnamamide 130
Chemistry of the Dihydrothiazine Ring Moiety of Cephalosporins. A Route to 3-Formoxymethyl-3-Cephem Derivatives 129
(E)-(methyloxyimino)acetamides as analogues of neuroleptic benzamides: Synthesis and D-2-dopaminergic binding affinity 125
Antiherpes virus agents: A review 124
Allosteric inhibition of (125I) ET-1 binding to ET(A) receptors by aldoxime and hydroxamic acid derivatives 123
Synthesis and evaluation of beta3-adrenergic affinity of new oximethereal derivative 122
Oximethereal piperidinic derivatives: synthesis and affinity for serotonin and dopamine transporters 122
Conformational effects on the activity of drugs. 11. Stereostructural models for the direct activation of the a- and ß-adrenergic receptor 122
An anomalous effect of N-isopropyl substitution in determining beta-adrenergic activity 120
Conformational effects on the activity of drugs. 10. Synthesis, conformation, and pharmacological properties of 1-(2,5-dimethoxyphenyl)-2-aminoethanols and their morpholine analogues 119
SYNTHESIS AND AFFINITY FOR SEROTONIN TRANSPORTER OF NEW PIPERIDINE BASED BIVALENT LIGANDS 115
Sintesi e proprietà alfa-adrenergiche di derivati cromanici, quali analoghi conformazionalmente ristretti dell’1-(2,5-dimetossifenil)-2-amminoetanolo 114
Synthesis and binding affinity at beta-adrenergic receptors of semirigid dichloroisoproterenol analogues, 114
Sintesi e affinità per il trasportatore della serotonina di nuovi derivati piperidinici ossimeterei 111
Synthesis and pharmacological properties of cis-2-(2,5-dimethoxyphenyl)-3-methylmorpholine and its N-isopropyl derivative 110
Conformationally restrained analogues of sympathomimetic catecholamines. Synthesis and adrenergic activity of 5,6- and 6,7-dihydroxy-3,4-dihydrospiro[naphthalen-1(2H)-2',5'-morpholines] 107
Synthesis and ß-adrenergic properties of tetrahydronaphthalene analogs of dichloroisoproterenol 106
CONFORMATIONAL EFFECTS ON DRUG ACTIVITY .6. SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF 2-(PARANITROPHENYL) SUBSTITUTED MORPHOLINES 106
Acidi benzilideneamminossipropionici sostituiti sul fenile. Sintesi e proprietà antiinfiammatorie. 104
null 103
Sintesi e proprietà inibitrici nei confronti delle cicloossigenasi di ammidi dell'acido 2-(4-metilsulfonilfenil)-1-ciclopentenico e di suoi analoghi eteroaromatici 98
Derivati della 3-imminossimetilpiperidina inibitori dell’uptake delle monoammine nelle frazioni sinaptosomiali cerebrali. 98
Synthesis and stereochemistry of (Z)- and (E)-(3,4,5-trimethoxy)-a,ß-dimethylcinnamic acids and diastereoisomeric intermediate ß-hydroxy esters 97
Derivati 4-arilpiperidinici e loro uso per la preparazione di un medicamento per il trattamento di disordini del SNC 96
Synthesis and biological evaluation of sulindac derivatives as potential anticancer agents 93
Sintesi e stereochimica degli acidi (Z)- e (E)-(3,4,5-trimetossi)-alfa,beta-dimetilcinnamico e dei beta-idrossiesteri diastereoisomeri intermedi. 84
2-Imminossimetil morfoline attive sul sistema nervoso centrale. Sintesi e proprietà antidepressive. 84
Sintesi, conformazione e proprietà farmacologiche di 1-(2,5-dimetossi fenil)-2-amminoetanoli e dei loro analoghi morfolinici. Un contributo alla conoscenza delle richieste steriche del recettore a-adrenergico 82
Synthesis, molecular docking and binding studies of selective serotonin transporter inhibitors 79
Nuovi derivati piperidinici: sintesi e proprietà biologiche 70
Totale 15.296
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Categoria #
all - tutte 41.468
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 41.468
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.138 0 80 17 91 227 135 26 52 49 42 77 342
2022/20231.328 195 154 105 142 136 194 16 83 210 11 70 12
2023/2024848 128 91 113 47 95 155 38 30 13 21 24 93
2024/20253.124 14 119 45 196 384 324 294 196 275 371 352 554
2025/20262.880 259 390 377 234 253 251 490 119 139 228 99 41
2026/2027239 56 183 0 0 0 0 0 0 0 0 0 0
Totale 15.296